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The map label for this gene is mntH [H]

Identifier: 157370158

GI number: 157370158

Start: 2099464

End: 2100768

Strand: Direct

Name: mntH [H]

Synonym: Spro_1916

Alternate gene names: 157370158

Gene position: 2099464-2100768 (Clockwise)

Preceding gene: 157370156

Following gene: 157370160

Centisome position: 38.53

GC content: 57.85

Gene sequence:

>1305_bases
ATGCGTGATGCGGCAACCACCACATCGTTAACCGAACGAACCAATACGGCAATTGGTAACGCACTTGCCGGGCGTAAGCG
TGGTGCATTCACGCCGCTACTGTTCGCCGGCCCTGCAGTGATTGCCTCTATTGCTTATATGGACCCCGGTAATTTCGCCA
CCAATATTCAGGCCGGTTCGAAATACGGCTACAGCCTGTTATGGGTGGTGGTGATGGCGAACCTGATCGCCATGCTGTTT
CAGGCGCTGTCGGCCAAGCTGGGTATCGTCACCAACCGCAATCTGGCGGAAATGTGCCGCGATCAATTTTCTCGTCCGGT
GGTCATTGGCATGTGGTTGCTCAGTGAGGTGGCGGCAATGGCTACCGATCTGGCGGAGTTTCTCGGCGGTGCGATAGCGC
TGGCGTTACTGTTCAATATGCCGCTGCTGCCAGGCATGGGGGTGACGGCGGTGATCACCTATGCCTTGCTGATGGTGGAG
AAGAAAGGTTTCCGTCCGGTAGAACTGATGATCGGCGGCTTGGTCGCGGTGATTGCCCTGTGTTATCTGGTCGAGATGTT
TATCGTGCCGGTCGATTGGGCGGCAGCGGGCATGGGCATGGTCACGCCGCAGTTGCCGGATGCACAGGCGCTGACCATTG
CCGTCGGTATCATTGGTGCCACCGTGATGCCGCACGCCATCTTCCTGCACTCGGGGCTGACCCAGCACCGTGCGCCGGCC
AGTGACAGCGGCGAGCGCCGTAAACTGCTGCGTTTTTCCAATATTGAAGTGGTGATTGCGCTATCTATCGCCGGGATGGT
GAATATCGCCATGGTGATTATGGCCTCCAGCGCCTTCCATGCCGGTAATAGCGATGTGGCTGAGATCGGTACCGCTTATC
ATACGCTGACGCCACTGTTTGGTGCCGCCGCCGCCGGTATCTTCCTGATGTCGCTGATTGCCTCCGGGATTTCCAGTTCG
GTGGTGGGTACCATGGCGGGCCAGATGATCATGCAGGGCTTTGTCGGTTTCCGCATTCCGGTATGGGTCCGCCGCATGGT
GACCATGATCCCGGCGTTCATCGTGGTCGCGTTAGGGGTTAATGCCACGGATGCACTGGTTTACAGCCAGGTGGTGCTGA
GCCTGGCGCTGCCGGCGCCGATGATTGCTCTGGTGATGTTCACCCGCCGTCGCGACATTATGGGCGAATTTGTCAACGGT
CGCCTGACCAGCCTGGTGTCAATCATCGGAACGGTGATTATTATCCTGCTCAATATGGTGTTGCTGCTGCAGACTTTCGG
CGTTGCTATCCCCGGTCTGGGTTAA

Upstream 100 bases:

>100_bases
ACAAAGGCAGTGAATCTTCCATTTTGCATAAAGTGTAGCCGATGCTACATTGCTGTGAGTGTTGGGTGAAAAATAACCAG
AAAAAGATTGAGGGTAAATC

Downstream 100 bases:

>100_bases
CTGACAAGCCGTGCAGTCGTTGCTGTCACGGCTTGACGTCCAAACCATCACTGCTACAAATTCCCCACGCCGCCGTCGAT
CAACAACTCACTGCCGACCA

Product: Mn2+/Fe2+ transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRDAATTTSLTERTNTAIGNALAGRKRGAFTPLLFAGPAVIASIAYMDPGNFATNIQAGSKYGYSLLWVVVMANLIAMLF
QALSAKLGIVTNRNLAEMCRDQFSRPVVIGMWLLSEVAAMATDLAEFLGGAIALALLFNMPLLPGMGVTAVITYALLMVE
KKGFRPVELMIGGLVAVIALCYLVEMFIVPVDWAAAGMGMVTPQLPDAQALTIAVGIIGATVMPHAIFLHSGLTQHRAPA
SDSGERRKLLRFSNIEVVIALSIAGMVNIAMVIMASSAFHAGNSDVAEIGTAYHTLTPLFGAAAAGIFLMSLIASGISSS
VVGTMAGQMIMQGFVGFRIPVWVRRMVTMIPAFIVVALGVNATDALVYSQVVLSLALPAPMIALVMFTRRRDIMGEFVNG
RLTSLVSIIGTVIIILLNMVLLLQTFGVAIPGLG

Sequences:

>Translated_434_residues
MRDAATTTSLTERTNTAIGNALAGRKRGAFTPLLFAGPAVIASIAYMDPGNFATNIQAGSKYGYSLLWVVVMANLIAMLF
QALSAKLGIVTNRNLAEMCRDQFSRPVVIGMWLLSEVAAMATDLAEFLGGAIALALLFNMPLLPGMGVTAVITYALLMVE
KKGFRPVELMIGGLVAVIALCYLVEMFIVPVDWAAAGMGMVTPQLPDAQALTIAVGIIGATVMPHAIFLHSGLTQHRAPA
SDSGERRKLLRFSNIEVVIALSIAGMVNIAMVIMASSAFHAGNSDVAEIGTAYHTLTPLFGAAAAGIFLMSLIASGISSS
VVGTMAGQMIMQGFVGFRIPVWVRRMVTMIPAFIVVALGVNATDALVYSQVVLSLALPAPMIALVMFTRRRDIMGEFVNG
RLTSLVSIIGTVIIILLNMVLLLQTFGVAIPGLG
>Mature_434_residues
MRDAATTTSLTERTNTAIGNALAGRKRGAFTPLLFAGPAVIASIAYMDPGNFATNIQAGSKYGYSLLWVVVMANLIAMLF
QALSAKLGIVTNRNLAEMCRDQFSRPVVIGMWLLSEVAAMATDLAEFLGGAIALALLFNMPLLPGMGVTAVITYALLMVE
KKGFRPVELMIGGLVAVIALCYLVEMFIVPVDWAAAGMGMVTPQLPDAQALTIAVGIIGATVMPHAIFLHSGLTQHRAPA
SDSGERRKLLRFSNIEVVIALSIAGMVNIAMVIMASSAFHAGNSDVAEIGTAYHTLTPLFGAAAAGIFLMSLIASGISSS
VVGTMAGQMIMQGFVGFRIPVWVRRMVTMIPAFIVVALGVNATDALVYSQVVLSLALPAPMIALVMFTRRRDIMGEFVNG
RLTSLVSIIGTVIIILLNMVLLLQTFGVAIPGLG

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=439, Percent_Identity=32.8018223234624, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI295293167, Length=442, Percent_Identity=32.1266968325792, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI295293178, Length=442, Percent_Identity=32.1266968325792, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI295293171, Length=441, Percent_Identity=31.5192743764172, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI295293169, Length=441, Percent_Identity=31.5192743764172, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI295293175, Length=442, Percent_Identity=32.1266968325792, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI295293173, Length=442, Percent_Identity=32.1266968325792, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI10835169, Length=442, Percent_Identity=32.1266968325792, Blast_Score=176, Evalue=5e-44,
Organism=Escherichia coli, GI1788736, Length=390, Percent_Identity=49.2307692307692, Blast_Score=370, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI193210616, Length=451, Percent_Identity=29.490022172949, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17569473, Length=395, Percent_Identity=31.6455696202532, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI71999499, Length=481, Percent_Identity=29.5218295218295, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI71993856, Length=246, Percent_Identity=33.739837398374, Blast_Score=142, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6323062, Length=389, Percent_Identity=34.9614395886889, Blast_Score=214, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6324450, Length=446, Percent_Identity=31.390134529148, Blast_Score=206, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6321841, Length=399, Percent_Identity=32.3308270676692, Blast_Score=185, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24648607, Length=455, Percent_Identity=33.1868131868132, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI281362176, Length=455, Percent_Identity=33.1868131868132, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24648609, Length=455, Percent_Identity=33.1868131868132, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI45553443, Length=435, Percent_Identity=33.1034482758621, Blast_Score=208, Evalue=7e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 45779; Mature: 45779

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCCCCC
>Mature Secondary Structure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HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA