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The map label for this gene is fabD [H]

Identifier: 157370147

GI number: 157370147

Start: 2089107

End: 2090036

Strand: Direct

Name: fabD [H]

Synonym: Spro_1905

Alternate gene names: 157370147

Gene position: 2089107-2090036 (Clockwise)

Preceding gene: 157370146

Following gene: 157370148

Centisome position: 38.34

GC content: 59.03

Gene sequence:

>930_bases
ATGACGCAATTTGCTTTTGTTTTTCCAGGCCAGGGTTCACAGACTCTGGGCATGCTGGCCGATTTGGCCACTCAATATCC
GATCGTTGAAGCGACCTTCAGCGAAGCCTCTTCCGTCCTGGGTTACGACCTATGGCAGCTGGTGCAGCAAGGGCCGGCGG
AAGAACTGAATAAAACCTGGCAGACGCAGCCGGCATTGCTGGCCGCTTCCGTAGCCATTTTCCGCGTCTGGCAGCAGCAG
GGCGGTAAAGCACCTGCCATCATGGCTGGCCATAGCCTGGGTGAATACTCGGCGCTGGTGTGTGCGGGCGTGCTGGATTT
CCAGGCGGCAATCCGTCTGGTTGAGCTGCGCGGCAAACTGATGCAGGAAGCGGTGCCGGAAGGCACTGGCGCGATGTCCG
CCATTATCGGCCTGGACAACGCCGCCATCGCCAAGGCTTGTGAAGAGTCTGCCCAGGGGCAGGTTGTTTCACCGGTGAAC
TTTAACTCACCGGGCCAGGTGGTGATCGCCGGCAATAAAGAAGCGGTTGAACGTGCTGGTGCGGCCTGTAAAGCCGCTGG
CGCCAAGCGTGCGTTGCCATTGCCGGTGAGCGTGCCTTCGCACTGCGCACTGATGAAACCGGCCGCAGACAAGCTGGCTG
TGGCGTTGCAGGAGATTACCTTCAACGCACCGCAGGTCCCGGTGGTGAATAACGTCGACGTGAGCACCGAAACCGATCCA
GAAGCGATCCGCAGTGCACTGGTGCGTCAGTTGTACAGCCCGGTACGTTGGACCGAAAGCGTAGAGTTTATGGCAGCACA
GGGCGTTACCTTGCTGCTAGAGGTTGGTCCGGGTAAAGTTCTGACCGGTCTGACTAAACGTATTGTTGACACCCTGACGG
CGGCGGCGGTTAATGACGCAGCCAGCCTGACAGCGGCGCTTGAACAATAA

Upstream 100 bases:

>100_bases
GGCGGATCCAACGCGGCCAACTGGTGCTGCTGGAAGCCTTTGGCGGCGGCTTTACCTGGGGCTCGGCGCTGGTTCGTTTC
TGATATAACAGGAAGAAAAA

Downstream 100 bases:

>100_bases
AGAGGAAAACAATGAGCTTCGAAGGTAAAGTTGTTCTGGTCACCGGCGCCAGCCGGGGTATTGGCCGGGCTATTGCAGAA
ACGTTTGTGGCACGTGGCGC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTQFAFVFPGQGSQTLGMLADLATQYPIVEATFSEASSVLGYDLWQLVQQGPAEELNKTWQTQPALLAASVAIFRVWQQQ
GGKAPAIMAGHSLGEYSALVCAGVLDFQAAIRLVELRGKLMQEAVPEGTGAMSAIIGLDNAAIAKACEESAQGQVVSPVN
FNSPGQVVIAGNKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADKLAVALQEITFNAPQVPVVNNVDVSTETDP
EAIRSALVRQLYSPVRWTESVEFMAAQGVTLLLEVGPGKVLTGLTKRIVDTLTAAAVNDAASLTAALEQ

Sequences:

>Translated_309_residues
MTQFAFVFPGQGSQTLGMLADLATQYPIVEATFSEASSVLGYDLWQLVQQGPAEELNKTWQTQPALLAASVAIFRVWQQQ
GGKAPAIMAGHSLGEYSALVCAGVLDFQAAIRLVELRGKLMQEAVPEGTGAMSAIIGLDNAAIAKACEESAQGQVVSPVN
FNSPGQVVIAGNKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADKLAVALQEITFNAPQVPVVNNVDVSTETDP
EAIRSALVRQLYSPVRWTESVEFMAAQGVTLLLEVGPGKVLTGLTKRIVDTLTAAAVNDAASLTAALEQ
>Mature_308_residues
TQFAFVFPGQGSQTLGMLADLATQYPIVEATFSEASSVLGYDLWQLVQQGPAEELNKTWQTQPALLAASVAIFRVWQQQG
GKAPAIMAGHSLGEYSALVCAGVLDFQAAIRLVELRGKLMQEAVPEGTGAMSAIIGLDNAAIAKACEESAQGQVVSPVNF
NSPGQVVIAGNKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADKLAVALQEITFNAPQVPVVNNVDVSTETDPE
AIRSALVRQLYSPVRWTESVEFMAAQGVTLLLEVGPGKVLTGLTKRIVDTLTAAAVNDAASLTAALEQ

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=300, Percent_Identity=33.6666666666667, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=41.2844036697248, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1787334, Length=308, Percent_Identity=83.4415584415584, Blast_Score=503, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI71984332, Length=294, Percent_Identity=30.6122448979592, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=297, Percent_Identity=30.976430976431, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24665753, Length=298, Percent_Identity=33.5570469798658, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32295; Mature: 32164

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQFAFVFPGQGSQTLGMLADLATQYPIVEATFSEASSVLGYDLWQLVQQGPAEELNKTW
CCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QTQPALLAASVAIFRVWQQQGGKAPAIMAGHSLGEYSALVCAGVLDFQAAIRLVELRGKL
CCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQEAVPEGTGAMSAIIGLDNAAIAKACEESAQGQVVSPVNFNSPGQVVIAGNKEAVERAG
HHHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCEECCCCCCCCCCEEEECCHHHHHHHC
AACKAAGAKRALPLPVSVPSHCALMKPAADKLAVALQEITFNAPQVPVVNNVDVSTETDP
CHHHHCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
EAIRSALVRQLYSPVRWTESVEFMAAQGVTLLLEVGPGKVLTGLTKRIVDTLTAAAVNDA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
ASLTAALEQ
HHHHHHHCC
>Mature Secondary Structure 
TQFAFVFPGQGSQTLGMLADLATQYPIVEATFSEASSVLGYDLWQLVQQGPAEELNKTW
CEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QTQPALLAASVAIFRVWQQQGGKAPAIMAGHSLGEYSALVCAGVLDFQAAIRLVELRGKL
CCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQEAVPEGTGAMSAIIGLDNAAIAKACEESAQGQVVSPVNFNSPGQVVIAGNKEAVERAG
HHHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCEECCCCCCCCCCEEEECCHHHHHHHC
AACKAAGAKRALPLPVSVPSHCALMKPAADKLAVALQEITFNAPQVPVVNNVDVSTETDP
CHHHHCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
EAIRSALVRQLYSPVRWTESVEFMAAQGVTLLLEVGPGKVLTGLTKRIVDTLTAAAVNDA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
ASLTAALEQ
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]