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The map label for this gene is hexR [H]

Identifier: 157370096

GI number: 157370096

Start: 2036766

End: 2037908

Strand: Reverse

Name: hexR [H]

Synonym: Spro_1854

Alternate gene names: 157370096

Gene position: 2037908-2036766 (Counterclockwise)

Preceding gene: 157370102

Following gene: 157370095

Centisome position: 37.4

GC content: 56.87

Gene sequence:

>1143_bases
ATGGATCTCGTTTACCACATTCAATTCCGTCAGGATCCGTTCAACCGGCAGGAGGCAAAAATTGCCCGAACCATCCTGGA
CAATCCCGGATTCACTTCAACCGCGACTATTGAACAGTTGGCTGAACGGGCCGGCGTCAGTACCGAGATAGTCGCCCATT
TTGCCCAATCTCTTGGTTGTCAGGATCTTAACGACTTTATCTCGTTGATGCGCACTCAGCCTGTGCCGGTAAACCCGCCG
GCAGCCGTGGCGCAACCGGTTCTGGGCGGCATGGATATCGCCTTCGCTTCCGCCGCCGGTATCGGCAAACTGCCCGGTGT
CAGCCCCACGACTTTGAGTCGCTTCGCCAAATCCATCGGTTGTGAAGATATTGGCGACATCGTCTATCAAATCCGCGCGC
GGCAAAACCAACTCAGTCAGCAGGAAGCCAAGGTTGCACAGACCATTCTGGACGATATCGCCTTTGCCTCTTCCGCTACC
ATAGAGCTGCTGGCCAGTCAGGCAGGGGTCAGCCCGGCGACTATCACCCGTTTCGCCAAAACCATAGGTTGTGATGATAT
TCGCGATCTGCGCATGAAGCTGGCACAGGCCAGCGTCAGTGGATCACGCTATTTGACTGCCCAAACGACGCCCAATGGGC
CACCTCGTTTGTGGCTGCAACGCGTCAACGACGTGGAAACCACGCTGCATCAACAGCTGCAACAGGTAGAACATTCGGCA
TTAATCGACGCCAGCCAACAGGTAAGCCAGTGCAAAAGCGTGCATATTTTTGGCGTAAACAGCATGGGGTTGTACGTCAA
CGAGCTGCAACAACGCCTGGTGGGTTTGGGCTATCCCGCTTTTGCCTGCCAGGATGCGGCACTGATGCGCATGACGGCCT
CCACCCTGAGTACGCAACAGTGTGTGATACTGCTCTCGCTGAGTGGAGAAAATACCGACTTGCTCAATGCCGCCAGGCTG
GCCGGCGCCACTGGCGCTTATCGCATCGCGTTGGCCCCAGCAGGCAGCACTCTGGCATCACTGGCCGATAAGGTCTTGCC
CCTGAGTGGTGGGAGTGCCGCACGCTACGGGCTGATGCTGACGCTGGACCTATTGCTGGCGCAGTTGCTGCCAGAAAGCC
TCGGTGCGCAAGCGGAAGATTAA

Upstream 100 bases:

>100_bases
CATTGGTTTATTCTGCCGGTCAGGGCTTTATAGCGTGCGAAAAACAGGCTAGTTTGAAGCACCGGGCATCGGTTGGCATA
ACAGAAGGGACACTGCAGTT

Downstream 100 bases:

>100_bases
ATCCACAAAACAACCCTTAACTATGGCGAACACCTGAGGTTTTTCCTAATTAGCCATCCAGATTGCCACTCCCTATTGAT
AGGAATATTCTTACTACGTT

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MDLVYHIQFRQDPFNRQEAKIARTILDNPGFTSTATIEQLAERAGVSTEIVAHFAQSLGCQDLNDFISLMRTQPVPVNPP
AAVAQPVLGGMDIAFASAAGIGKLPGVSPTTLSRFAKSIGCEDIGDIVYQIRARQNQLSQQEAKVAQTILDDIAFASSAT
IELLASQAGVSPATITRFAKTIGCDDIRDLRMKLAQASVSGSRYLTAQTTPNGPPRLWLQRVNDVETTLHQQLQQVEHSA
LIDASQQVSQCKSVHIFGVNSMGLYVNELQQRLVGLGYPAFACQDAALMRMTASTLSTQQCVILLSLSGENTDLLNAARL
AGATGAYRIALAPAGSTLASLADKVLPLSGGSAARYGLMLTLDLLLAQLLPESLGAQAED

Sequences:

>Translated_380_residues
MDLVYHIQFRQDPFNRQEAKIARTILDNPGFTSTATIEQLAERAGVSTEIVAHFAQSLGCQDLNDFISLMRTQPVPVNPP
AAVAQPVLGGMDIAFASAAGIGKLPGVSPTTLSRFAKSIGCEDIGDIVYQIRARQNQLSQQEAKVAQTILDDIAFASSAT
IELLASQAGVSPATITRFAKTIGCDDIRDLRMKLAQASVSGSRYLTAQTTPNGPPRLWLQRVNDVETTLHQQLQQVEHSA
LIDASQQVSQCKSVHIFGVNSMGLYVNELQQRLVGLGYPAFACQDAALMRMTASTLSTQQCVILLSLSGENTDLLNAARL
AGATGAYRIALAPAGSTLASLADKVLPLSGGSAARYGLMLTLDLLLAQLLPESLGAQAED
>Mature_380_residues
MDLVYHIQFRQDPFNRQEAKIARTILDNPGFTSTATIEQLAERAGVSTEIVAHFAQSLGCQDLNDFISLMRTQPVPVNPP
AAVAQPVLGGMDIAFASAAGIGKLPGVSPTTLSRFAKSIGCEDIGDIVYQIRARQNQLSQQEAKVAQTILDDIAFASSAT
IELLASQAGVSPATITRFAKTIGCDDIRDLRMKLAQASVSGSRYLTAQTTPNGPPRLWLQRVNDVETTLHQQLQQVEHSA
LIDASQQVSQCKSVHIFGVNSMGLYVNELQQRLVGLGYPAFACQDAALMRMTASTLSTQQCVILLSLSGENTDLLNAARL
AGATGAYRIALAPAGSTLASLADKVLPLSGGSAARYGLMLTLDLLLAQLLPESLGAQAED

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=215, Percent_Identity=26.046511627907, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 40466; Mature: 40466

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLVYHIQFRQDPFNRQEAKIARTILDNPGFTSTATIEQLAERAGVSTEIVAHFAQSLGC
CCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCC
QDLNDFISLMRTQPVPVNPPAAVAQPVLGGMDIAFASAAGIGKLPGVSPTTLSRFAKSIG
CCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCC
CEDIGDIVYQIRARQNQLSQQEAKVAQTILDDIAFASSATIELLASQAGVSPATITRFAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHH
TIGCDDIRDLRMKLAQASVSGSRYLTAQTTPNGPPRLWLQRVNDVETTLHQQLQQVEHSA
HHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIDASQQVSQCKSVHIFGVNSMGLYVNELQQRLVGLGYPAFACQDAALMRMTASTLSTQQ
HHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
CVILLSLSGENTDLLNAARLAGATGAYRIALAPAGSTLASLADKVLPLSGGSAARYGLML
EEEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHH
TLDLLLAQLLPESLGAQAED
HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDLVYHIQFRQDPFNRQEAKIARTILDNPGFTSTATIEQLAERAGVSTEIVAHFAQSLGC
CCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCC
QDLNDFISLMRTQPVPVNPPAAVAQPVLGGMDIAFASAAGIGKLPGVSPTTLSRFAKSIG
CCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCC
CEDIGDIVYQIRARQNQLSQQEAKVAQTILDDIAFASSATIELLASQAGVSPATITRFAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHH
TIGCDDIRDLRMKLAQASVSGSRYLTAQTTPNGPPRLWLQRVNDVETTLHQQLQQVEHSA
HHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIDASQQVSQCKSVHIFGVNSMGLYVNELQQRLVGLGYPAFACQDAALMRMTASTLSTQQ
HHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
CVILLSLSGENTDLLNAARLAGATGAYRIALAPAGSTLASLADKVLPLSGGSAARYGLML
EEEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHH
TLDLLLAQLLPESLGAQAED
HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 1704005; 7567469 [H]