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The map label for this gene is pgsA [H]

Identifier: 157370092

GI number: 157370092

Start: 2034203

End: 2034751

Strand: Direct

Name: pgsA [H]

Synonym: Spro_1850

Alternate gene names: 157370092

Gene position: 2034203-2034751 (Clockwise)

Preceding gene: 157370091

Following gene: 157370093

Centisome position: 37.33

GC content: 54.1

Gene sequence:

>549_bases
ATGCAATTGAATATACCGACTTGGCTTACTCTGTTTCGCGTAGTTCTGATCCCATTCTTTGTTCTGGCATTTTATCTGCC
GTTCACCTGGGCTCCGATGGTTTGTGCCGTCATCTTTGTGTTTGCTGCCATAACCGACTGGTTTGATGGTTTCCTCGCCC
GTCGCTGGAAGCAAACTACCCGTTTCGGGGCCTTCCTCGACCCGGTTGCGGACAAGGTGATGGTCGCGGTGGCACTGGTG
CTGGTGGCTGAACACTACCACGCTTGGTGGATCACGCTACCGGCGGCGACCATGATTGCTCGTGAAATTATCATCTCGTC
ACTGCGTGAGTGGATGGCGGAGATTGGTAAGCGCAGCAGTGTCGCGGTGTCCTGGATTGGCAAGGTAAAAACCATGGCGC
AGATGATGTCGCTGGTCGGCCTGCTGTGGCGCCCGGACCGTACCGTTGAGTATGTGTCCTTTGGTTTGTTGTACATCGCT
GCGGTGCTGACTTTCTGGTCAATGTTCCAATATTTGAACGCTGCCCGCAGAGATTTGCTGGAACCCTGA

Upstream 100 bases:

>100_bases
CAAGCATTGGCAGAAAAGATCTACAATGCATTGAAACACTGAGGGCAATGTAGCAACATACTCTTAATTCCCACTCCAGC
CAGATAGTTACCCTAGCATT

Downstream 100 bases:

>100_bases
TCAAAGCGCTGCAAAAATCGTCAAACAAACGTAATGAGCCAACAATTTTATTGACTCATTACGTCAGGTAAGTAGAATGC
ATCGCATCAGACGGCAGCAG

Product: phosphatidylglycerophosphate synthetase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MQLNIPTWLTLFRVVLIPFFVLAFYLPFTWAPMVCAVIFVFAAITDWFDGFLARRWKQTTRFGAFLDPVADKVMVAVALV
LVAEHYHAWWITLPAATMIAREIIISSLREWMAEIGKRSSVAVSWIGKVKTMAQMMSLVGLLWRPDRTVEYVSFGLLYIA
AVLTFWSMFQYLNAARRDLLEP

Sequences:

>Translated_182_residues
MQLNIPTWLTLFRVVLIPFFVLAFYLPFTWAPMVCAVIFVFAAITDWFDGFLARRWKQTTRFGAFLDPVADKVMVAVALV
LVAEHYHAWWITLPAATMIAREIIISSLREWMAEIGKRSSVAVSWIGKVKTMAQMMSLVGLLWRPDRTVEYVSFGLLYIA
AVLTFWSMFQYLNAARRDLLEP
>Mature_182_residues
MQLNIPTWLTLFRVVLIPFFVLAFYLPFTWAPMVCAVIFVFAAITDWFDGFLARRWKQTTRFGAFLDPVADKVMVAVALV
LVAEHYHAWWITLPAATMIAREIIISSLREWMAEIGKRSSVAVSWIGKVKTMAQMMSLVGLLWRPDRTVEYVSFGLLYIA
AVLTFWSMFQYLNAARRDLLEP

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=181, Percent_Identity=76.2430939226519, Blast_Score=285, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20989; Mature: 20989

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNIPTWLTLFRVVLIPFFVLAFYLPFTWAPMVCAVIFVFAAITDWFDGFLARRWKQTT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGAFLDPVADKVMVAVALVLVAEHYHAWWITLPAATMIAREIIISSLREWMAEIGKRSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VAVSWIGKVKTMAQMMSLVGLLWRPDRTVEYVSFGLLYIAAVLTFWSMFQYLNAARRDLL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EP
CC
>Mature Secondary Structure
MQLNIPTWLTLFRVVLIPFFVLAFYLPFTWAPMVCAVIFVFAAITDWFDGFLARRWKQTT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGAFLDPVADKVMVAVALVLVAEHYHAWWITLPAATMIAREIIISSLREWMAEIGKRSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VAVSWIGKVKTMAQMMSLVGLLWRPDRTVEYVSFGLLYIAAVLTFWSMFQYLNAARRDLL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA