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The map label for this gene is trkG [H]

Identifier: 157370053

GI number: 157370053

Start: 1995785

End: 1997245

Strand: Reverse

Name: trkG [H]

Synonym: Spro_1811

Alternate gene names: 157370053

Gene position: 1997245-1995785 (Counterclockwise)

Preceding gene: 157370054

Following gene: 157370052

Centisome position: 36.65

GC content: 53.18

Gene sequence:

>1461_bases
ATGGTCAAGAATAAGCAGATTCTGGTCGTTATTCATCTTTGCAGTTTTTTAGTTTTCCTTTACAGCCTGTCAATGATTCC
CCCTCTGTTGGTGGCATTGTTGTATAAAGAAAAAAGCGTTTTTTCTTTCTTCTATACGCTGGTGATTGCCGGTTCGCTCG
GCGGTTTGGGCTGGTTTAGCACCCGTCAGTCCAGGGTACAGCTGCGCACGCAGGACGGTTTTTTAATCATTGTGCTGTTC
TGGCTGCTGTTTTCCATGGTCAGCGCCCTGCCATTATGGATGGACGACACGCTAAACATCAGCCTGACCGATGCCATGTT
CGAAGGCGTTTCCGGTATTACCACCACCGGCGCTTCGGTGCTCAATGATGTTTCCGGCCTGCCTAAATCTTTCCTCTACT
ACCGCTCCCAGCTCAATTTTATCGGCGGCCTCGGCGTCATTGTGTTGGCCGTGGCGGTACTGCCGTTGCTCGGCATTGGT
GGCGCCAAGCTTTATCAGTCGGAAATGCCCGGCCCGTTCAAGGAAGAACGCCTGACCCCGCGACTGGCCGACACTTCAAA
AAACCTGTGGCTGATTTATCTCGGTCTGGGATTGGCCTGCACGGTGGCGTTCCGCATTGCCGGCATGCAGTGGTTTGATG
CCCTCTGCCACGGAATTTCCACCGTTTCACTCGGGGGGTTTTCCACCCGCAATGAGAGCCTGGGCTTTTACGATAGCTCG
GCGGTGGAAATGGTCGGCGGGATTTTCTCTATCCTGGCGGCGGTGAACTTCACCCTGTATTTCGTCGTCGTAGGCCGCCG
CAGCCTGAAGCCACTCTACAGAAACCCGGAACTGCGCTTTTTCCTGCTGGTGCTGTCAATTATCGTGGCGATTGTCTGCT
TTGAGCTGTACCGCTCTGGCATGTACGGTGCCAAAGACTCCTTCGTACACGGCTTTTTCCTCACCAGTTCGATGATGACC
GATAACGGGCTGGCCACCGCCGACTATGCCAAAATGCCCTCTCACACCATTATGTTGCTGTTGGCGGCAAGCTTTTTCGG
CGGTTGTGTCGGTTCTACCTGCGGCGGTATCAAGGCACTGCGTTTTCTGATCATGTACAAGCAGAGCCGGCATGAGATTA
ACCAACTGGTTCATCCCAACGCCATTTTCACCATCAAGGTTGGCAATGCGCCTATTCAGGATCGCGTGTTGCGTTCGGTC
TGGAGCTTCTTCTTTCTGTATGTCTTCTTCAGCTGTTTCTTCGTTTGGCTGCTGAACCTGATGGGCTATGACCTGGTTAC
TTCCTTCGCCACCGTCGCCGCCTGTATCAATAATATGGGATTAGGCTTTGGTGAAACCGCCGCCGGGTTTGGTACGCTCA
GCGATGCGGCCAAATGGCTGATGTGCTCGGCGATGCTGCTTGGCCGCCTTGAGATTTACCCTATGTTGATTTTGTGCTCA
CGCGCCTTTTGGCGTTTTTGA

Upstream 100 bases:

>100_bases
ACGATATGAATTTTTACGCCTTTTTTATATCGTCTGCCTTATTCTTTATATACTTAAAGAATAAATTGACTCATTGCCGA
CAGGCAACTCGGGCGCAAGT

Downstream 100 bases:

>100_bases
TACCTCGGCCCTGTCGCCGCACTGCCTGTTTTCATCAACTTTGCTGTACCAACGCTGACACATTCATAACGTGAATGTGT
TGCATTGTTGTATTCGTTTC

Product: TrkH family potassium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MVKNKQILVVIHLCSFLVFLYSLSMIPPLLVALLYKEKSVFSFFYTLVIAGSLGGLGWFSTRQSRVQLRTQDGFLIIVLF
WLLFSMVSALPLWMDDTLNISLTDAMFEGVSGITTTGASVLNDVSGLPKSFLYYRSQLNFIGGLGVIVLAVAVLPLLGIG
GAKLYQSEMPGPFKEERLTPRLADTSKNLWLIYLGLGLACTVAFRIAGMQWFDALCHGISTVSLGGFSTRNESLGFYDSS
AVEMVGGIFSILAAVNFTLYFVVVGRRSLKPLYRNPELRFFLLVLSIIVAIVCFELYRSGMYGAKDSFVHGFFLTSSMMT
DNGLATADYAKMPSHTIMLLLAASFFGGCVGSTCGGIKALRFLIMYKQSRHEINQLVHPNAIFTIKVGNAPIQDRVLRSV
WSFFFLYVFFSCFFVWLLNLMGYDLVTSFATVAACINNMGLGFGETAAGFGTLSDAAKWLMCSAMLLGRLEIYPMLILCS
RAFWRF

Sequences:

>Translated_486_residues
MVKNKQILVVIHLCSFLVFLYSLSMIPPLLVALLYKEKSVFSFFYTLVIAGSLGGLGWFSTRQSRVQLRTQDGFLIIVLF
WLLFSMVSALPLWMDDTLNISLTDAMFEGVSGITTTGASVLNDVSGLPKSFLYYRSQLNFIGGLGVIVLAVAVLPLLGIG
GAKLYQSEMPGPFKEERLTPRLADTSKNLWLIYLGLGLACTVAFRIAGMQWFDALCHGISTVSLGGFSTRNESLGFYDSS
AVEMVGGIFSILAAVNFTLYFVVVGRRSLKPLYRNPELRFFLLVLSIIVAIVCFELYRSGMYGAKDSFVHGFFLTSSMMT
DNGLATADYAKMPSHTIMLLLAASFFGGCVGSTCGGIKALRFLIMYKQSRHEINQLVHPNAIFTIKVGNAPIQDRVLRSV
WSFFFLYVFFSCFFVWLLNLMGYDLVTSFATVAACINNMGLGFGETAAGFGTLSDAAKWLMCSAMLLGRLEIYPMLILCS
RAFWRF
>Mature_486_residues
MVKNKQILVVIHLCSFLVFLYSLSMIPPLLVALLYKEKSVFSFFYTLVIAGSLGGLGWFSTRQSRVQLRTQDGFLIIVLF
WLLFSMVSALPLWMDDTLNISLTDAMFEGVSGITTTGASVLNDVSGLPKSFLYYRSQLNFIGGLGVIVLAVAVLPLLGIG
GAKLYQSEMPGPFKEERLTPRLADTSKNLWLIYLGLGLACTVAFRIAGMQWFDALCHGISTVSLGGFSTRNESLGFYDSS
AVEMVGGIFSILAAVNFTLYFVVVGRRSLKPLYRNPELRFFLLVLSIIVAIVCFELYRSGMYGAKDSFVHGFFLTSSMMT
DNGLATADYAKMPSHTIMLLLAASFFGGCVGSTCGGIKALRFLIMYKQSRHEINQLVHPNAIFTIKVGNAPIQDRVLRSV
WSFFFLYVFFSCFFVWLLNLMGYDLVTSFATVAACINNMGLGFGETAAGFGTLSDAAKWLMCSAMLLGRLEIYPMLILCS
RAFWRF

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA. TrkE increases the affinity of the system [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=484, Percent_Identity=65.0826446280992, Blast_Score=661, Evalue=0.0,
Organism=Escherichia coli, GI48994987, Length=479, Percent_Identity=41.544885177453, Blast_Score=362, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53777; Mature: 53777

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKNKQILVVIHLCSFLVFLYSLSMIPPLLVALLYKEKSVFSFFYTLVIAGSLGGLGWFS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
TRQSRVQLRTQDGFLIIVLFWLLFSMVSALPLWMDDTLNISLTDAMFEGVSGITTTGASV
CCHHHEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHCCCCCHHHHHHH
LNDVSGLPKSFLYYRSQLNFIGGLGVIVLAVAVLPLLGIGGAKLYQSEMPGPFKEERLTP
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHCCCC
RLADTSKNLWLIYLGLGLACTVAFRIAGMQWFDALCHGISTVSLGGFSTRNESLGFYDSS
CHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCH
AVEMVGGIFSILAAVNFTLYFVVVGRRSLKPLYRNPELRFFLLVLSIIVAIVCFELYRSG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
MYGAKDSFVHGFFLTSSMMTDNGLATADYAKMPSHTIMLLLAASFFGGCVGSTCGGIKAL
CCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
RFLIMYKQSRHEINQLVHPNAIFTIKVGNAPIQDRVLRSVWSFFFLYVFFSCFFVWLLNL
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGYDLVTSFATVAACINNMGLGFGETAAGFGTLSDAAKWLMCSAMLLGRLEIYPMLILCS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAFWRF
HHHHCC
>Mature Secondary Structure
MVKNKQILVVIHLCSFLVFLYSLSMIPPLLVALLYKEKSVFSFFYTLVIAGSLGGLGWFS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
TRQSRVQLRTQDGFLIIVLFWLLFSMVSALPLWMDDTLNISLTDAMFEGVSGITTTGASV
CCHHHEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHCCCCCHHHHHHH
LNDVSGLPKSFLYYRSQLNFIGGLGVIVLAVAVLPLLGIGGAKLYQSEMPGPFKEERLTP
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHCCCC
RLADTSKNLWLIYLGLGLACTVAFRIAGMQWFDALCHGISTVSLGGFSTRNESLGFYDSS
CHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCH
AVEMVGGIFSILAAVNFTLYFVVVGRRSLKPLYRNPELRFFLLVLSIIVAIVCFELYRSG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
MYGAKDSFVHGFFLTSSMMTDNGLATADYAKMPSHTIMLLLAASFFGGCVGSTCGGIKAL
CCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
RFLIMYKQSRHEINQLVHPNAIFTIKVGNAPIQDRVLRSVWSFFFLYVFFSCFFVWLLNL
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGYDLVTSFATVAACINNMGLGFGETAAGFGTLSDAAKWLMCSAMLLGRLEIYPMLILCS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAFWRF
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2022616; 9097039; 9278503 [H]