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The map label for this gene is ycbL [H]

Identifier: 157369971

GI number: 157369971

Start: 1901091

End: 1901738

Strand: Direct

Name: ycbL [H]

Synonym: Spro_1728

Alternate gene names: 157369971

Gene position: 1901091-1901738 (Clockwise)

Preceding gene: 157369970

Following gene: 157369977

Centisome position: 34.89

GC content: 56.64

Gene sequence:

>648_bases
ATGAAATACCACATTATTCCCGTTACCGCTTTTAGTCAGAACTGCAGCCTGATCTGGTGTGAGAGCACCCAGCAGGCGGC
GTTGGTCGATCCCGGCGGTGAACCTGAAAAACTGAAGGCCGAAATAGCCAGGCAGGGCGTAACCGTTACGCAGATCCTGC
TGACGCATGGTCATCTCGATCACGTTGGCGCGGCCGCTGAGTTGGCAGAGTTTTATCAGGTACCGATCTACGGCCCGGAT
AAGAGGGATGCTTTCTGGCTCGATGGCCTGCCTGCGCAGAGCCGCATGTTTGGGCTGGAAGAGTGCGCACCGCTGACGCC
AACCCAGTGGCTGGAAGAAGGGGATAGCGTGCAGGTGGGCGAAATGACGCTCAAGGTGCTGCATTGCCCTGGCCACACTC
CTGGCCATATCGTGTTTATTAATGATCAGGCGCGATTGGCGCTGGTGGGCGACGTGCTGTTTAACGGCGGCGTCGGGCGC
AGTGATTTCCCTCAAGGCGATCATCAGGCGTTGATTAACTCTATCCGCACCAAGTTATTGCCGCAGGGTGATGACATGGC
GTTTATTCCAGGTCATGGGCCAATGTCGACCTTCGGTCAAGAACGTGAAACCAACCCGTTCCTGCGTGAAGAGCCGGCCA
TCTGGTAA

Upstream 100 bases:

>100_bases
ACACATCGATACCGGCCCGGTGCGGACCTGGTAATCGCTGTGCACCACAAGTGAGTAGCGCCAGCCCGGCAGGGTGTGGC
GCCGTTGTCGTTGGAGCCTT

Downstream 100 bases:

>100_bases
GTTATTTCCGGCAGAAATAACTAAGGGGCGCTTTGAGCGCCCCTTTTGCTATGTGTCGCGCGACGGTTTTACAGCACGGC
GACGATGGCTTCGCACAGCG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKYHIIPVTAFSQNCSLIWCESTQQAALVDPGGEPEKLKAEIARQGVTVTQILLTHGHLDHVGAAAELAEFYQVPIYGPD
KRDAFWLDGLPAQSRMFGLEECAPLTPTQWLEEGDSVQVGEMTLKVLHCPGHTPGHIVFINDQARLALVGDVLFNGGVGR
SDFPQGDHQALINSIRTKLLPQGDDMAFIPGHGPMSTFGQERETNPFLREEPAIW

Sequences:

>Translated_215_residues
MKYHIIPVTAFSQNCSLIWCESTQQAALVDPGGEPEKLKAEIARQGVTVTQILLTHGHLDHVGAAAELAEFYQVPIYGPD
KRDAFWLDGLPAQSRMFGLEECAPLTPTQWLEEGDSVQVGEMTLKVLHCPGHTPGHIVFINDQARLALVGDVLFNGGVGR
SDFPQGDHQALINSIRTKLLPQGDDMAFIPGHGPMSTFGQERETNPFLREEPAIW
>Mature_215_residues
MKYHIIPVTAFSQNCSLIWCESTQQAALVDPGGEPEKLKAEIARQGVTVTQILLTHGHLDHVGAAAELAEFYQVPIYGPD
KRDAFWLDGLPAQSRMFGLEECAPLTPTQWLEEGDSVQVGEMTLKVLHCPGHTPGHIVFINDQARLALVGDVLFNGGVGR
SDFPQGDHQALINSIRTKLLPQGDDMAFIPGHGPMSTFGQERETNPFLREEPAIW

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI116642887, Length=248, Percent_Identity=28.6290322580645, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI21703352, Length=248, Percent_Identity=28.6290322580645, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI41327741, Length=197, Percent_Identity=27.9187817258883, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1787158, Length=215, Percent_Identity=69.7674418604651, Blast_Score=329, Evalue=8e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23621; Mature: 23621

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYHIIPVTAFSQNCSLIWCESTQQAALVDPGGEPEKLKAEIARQGVTVTQILLTHGHLD
CEEEEEEEEEECCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHCCCEEEHHHHHCCCHH
HVGAAAELAEFYQVPIYGPDKRDAFWLDGLPAQSRMFGLEECAPLTPTQWLEEGDSVQVG
HHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHCCHHHCCCCCHHHHHHCCCCEEEE
EMTLKVLHCPGHTPGHIVFINDQARLALVGDVLFNGGVGRSDFPQGDHQALINSIRTKLL
EEEEEEEECCCCCCCEEEEECCCCEEEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
PQGDDMAFIPGHGPMSTFGQERETNPFLREEPAIW
CCCCCEEEECCCCCHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKYHIIPVTAFSQNCSLIWCESTQQAALVDPGGEPEKLKAEIARQGVTVTQILLTHGHLD
CEEEEEEEEEECCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHCCCEEEHHHHHCCCHH
HVGAAAELAEFYQVPIYGPDKRDAFWLDGLPAQSRMFGLEECAPLTPTQWLEEGDSVQVG
HHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHCCHHHCCCCCHHHHHHCCCCEEEE
EMTLKVLHCPGHTPGHIVFINDQARLALVGDVLFNGGVGRSDFPQGDHQALINSIRTKLL
EEEEEEEECCCCCCCEEEEECCCCEEEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
PQGDDMAFIPGHGPMSTFGQERETNPFLREEPAIW
CCCCCEEEECCCCCHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]