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The map label for this gene is tycC [H]

Identifier: 157369941

GI number: 157369941

Start: 1858771

End: 1862607

Strand: Direct

Name: tycC [H]

Synonym: Spro_1698

Alternate gene names: 157369941

Gene position: 1858771-1862607 (Clockwise)

Preceding gene: 157369940

Following gene: 157369942

Centisome position: 34.11

GC content: 54.91

Gene sequence:

>3837_bases
ATGGATATTTCGGCGGGACTATTTGAACAGTTGGCTCAACACTACAGCCAGCAACCCGAAGCCATTGCGGTACAAGACGC
GGACAGCGTACTGAGTTATCGCGACTTCTGCCATCATGTTTTTAGTATTTCCTCCTGTTTGCGGCAGTGGATTAACACTG
ACAGAGTCTGTATCGGTTTATTCTGCGAGCCTTCCACTACTCTGGTAAGCGGTGCCTGGGGGATTTTGGCCAGCGGTTAT
GCTTATTTGCCGTTGGCGCCAGAATATCCCGATGAGCGGTTGCGTTATATGATTACCGACTCAGAGGTAAAAGTTATTCT
TTGCCAATATCATCTCAAAGAAAAATTGCAAACGCTGATCGGGCCAGATGTCACGATTATTACCGACAATGATATCCCTT
ATCTTTCTGATTTGCCCAAAGCGGTTTTTGACATTGCTGATTCTTCCGATGCCGCGCGGCTGGCTTATGTGATTTACACC
TCAGGCAGTTCGGGCAAACCGAAAGGCGTAATGGTCAGTTACCCTAATATTTCTCGTCATATGTATTACCTGTCCCATCG
TTTTGCTTTTGGCGCACAGAGTAAGATTTTGCAGAAAACGCCCATGAGTTTTGATGCGGCGCAGTGGGAGATCCTGGCGC
CGGCGATGGGATGTTCGCTGGTGATAGCACCGAAGGACTGCTACCGCGATCCGGATATGATGGTGGCGACCTTGCTGCGT
CATCAAATCACCAGCCTGCAATGCGTACCGACGCTGCTGCAAGCGCTGGTCGAGCAGCCACTGTTGCAGGATTGCCAGGC
GTTAACGCAGGTCTTTTGCGGTGGCGAAATATTGACGCGCAACCTGGCAAAGCAATTCTTTCAGTGCCTGCCGCAAGCTC
GCCTGATCAACCTGTATGGCCCAACGGAATGTACCATCAATGCGTCGGTGCATGAGGTTGAGAAAGAGGCTCTGGAACAG
TCACCTGACGCCGTTTCGATAGGTCGGCCGGTGGAGGATACCGCGTTTTATGTGCTTGATGCGCACCGTCAGCCGGTGGC
CGAGGGTGAAAAAGGCGAGCTGTACATCTCCGGTGTGCAGGTGGCCAATGGCTATTTGCTGCGTCCTGAGTTAACGGCTG
AACGGTTTCTGACGAATCCATTTAACTCTGCTGCGGAACATGCGCGCATGTATCGCACTGGCGATGTGGTTTACCGGGAT
AGCCTCGGCTGCTATCACTTTGCCGGCCGGGCAGATAACCAGATTAAACTGCGCGGTTACCGTATCGAGCTTGATGAAAT
TCGCCTGGCGATTGAGCGTCACCTCTGGGTGAAAAGGGCGGCGGTAATGGTCAATGAAGACGAGCGAACGCATTATCAAA
ACCTGATCGCCTGCGTCGAGTTGGACTCACAGCATGCGGCGTTGATGGATCAGGGGGTCCACGGCGAGCATCATCAGTCG
AAGGCCAGCAGGCAACAGGTCAAGGCGCAGCTGTCCAATGCGGGGTGCCGCAGCGAGGACGAGTGCCGGGCATTGCCCGC
AATCGCGCTTGCCGGCGCACAGGCTACGGCGCAGCAAAACTATCGGGCTTTCAGCCGCAAAAGTTACCGTTTCTTTGAAG
GGACGACGCGGGTTACCGAGGCGCAATTATTGTCAATTCTGGGGCGCAGCCCACGTGCCATGTTGGCGAGCGACCTGCAA
GCGCTGTCGGTGGAGGATTTTGGCGCACTGCTGCGTAACTTTGGCCAGTTCGCCAGTGAAAAACGATTGTTGCCCAAATA
CGCCTACGCATCACCGGGGGCGCTGTATTCGGTTCAGATGTATCTCGAGCTACACCGAATGTTTGGCTGGCCGGCGGGGA
TCTACTATTACCACCCTGTAAACCACCGCCTGTATTGCGTATGCGAACTGCCTGAACAGGCAACGGGCAGCCTTGAAATC
CACTTTATCGGCAAACGCGCGGCTATCGATCAGGTTTATCAGAACAATATTCAGGAGGTTCTGGAGATGGAGGCCGGTCA
TATGTTGGGGCTGTTCGATGAACTGCTGCCAGAATATGGTCTGCAGGCAGCCTCCGGCGCCCAGCCGGGGGCGTTGCCAC
AGTGGTATGACGGAGCCGCAACTGACTATTATTTCGGCGATTTTCGCATTCAGCCCGCCAATATGGAGGCCGTTGTCGAC
CACCCGGAATTTTTTGTCCAGGTTCATGCGCAGGGCGTCGCCGATATGTCTCCTGGGCTGTACCACTATCGCCAGGGCTC
GCTGCATTTTATGGATGAGGAGATCCTGGCACGCCACCACGTTATCGCTATCAACCAGCAAGTCTATCAGCGTGCGGGTT
TTGGCATCATGTTGGTGAACAACCATGCCGATGCTCAGGGGCATTACATTATGCTGGGGCGTGCGCTGCATCGTCTGCAA
GCCAATCCGCTGGGGCTGGGGATGATGTCGGCCGGCTATAGTTCGAAAAGCGGGCACGACTTGCCTGCTGCAAAGGCGAT
GCGGACGCTGTTGACCCGCCACGGGTTGCCGATGCAGAGCTGTTATTTCTGTATCGGCGGCCCGCTCAGCCAGTCGCAGC
TGTGTCATGACGGCATGGATGAGGATCGGGTGCATATGCAAGGGCCAACTGAAATGCTGAAAGCCGATTTAGCCGCGCAG
TTGCCACAATACATGATCCCGAACCGCGTGCTGGTCATGGACAAGCTGCCGCTGATGGCCAACGGTAAGGTCGACCAACA
AGCGCTTAATCGTATGTATGCTTGCCAACTGAATACCGAAAAGCCAATCGTGGTGCCGGAGGGCGAATTACAACAGCGTT
TGGCCGAAATCTGGTGCCGGGTCATGAAGTGGGAAAGGGTCTCTGCGGACGATGATTTCTTTGAGAGCGGGGGTAACTCA
CTCACCGCAGTCATGTTTATCAACCAGGTCAACAAAGCGCTCGATATTAAATTGCCGATGCAGATCCTGTTCCAAACGCC
GAACATCGTTGCTTTGGCCGACTGGATAGAACGCAATGCCTATCTCGCGCCACAGCTGTCGCGCTTGGTGCCCTTTAATC
GACAGCAGGCACCGGCGATTTTTTGCTGGCCAGGTCTGGGAGGCTATCCGCTAAGTCTGAAAGCGCTGGGAGAGAGTCTG
AGCCAGGCGCGTGCCTTTTATGGCGTGCAGGCGTTGGGCATTAACGAAGGGGAGCTGCCACTGGAGTCCATTCAGCAGAT
GGCGGCGGCAGATATCGCGCAAATCCGACGCTTGCAACCCCAGGGGCCCTATACGCTGTGGGGATACTCCTTCGGCGCAC
GCGTGGCTTTCGAGGCTGCCTACCAGCTGGAGGCCGAGGGGCAGGTGGTGGAGGAGCTGTACCTGATTGCTCCTGGTTCG
CCGAAAACGCAATTTGACCGAGAGCAAGAGGGTAACCAGCAGGTCAACTTCACCAATCCGGTGTTTGTGGCGATTTTATT
TTCCGTTTTTGCCCGCCAGGTGGAAGGGCCATTGCTTGAACGCTGTCTGGCAGAGTGCCGTGAAGAGGGGGACTTTGTGC
GTTTTATTTGCCGCTGTTTCCCACAGCTTCAGGTGGAACTGGTGGCGCGGATCATTGAGATCGTCAAGCAAACCTATGCC
TTCGGCTATAACTTCGAGGAACTGCAGCAACGCCAGGTTCGGGCGCCGGTGACCGTTATTAAAGCGGCCGGTGACCATTA
TTCCCAACTTGAAAATTCACCGGCCCTGCTGGCCAATCCGCTGCGGGTGATCTCGCTGGCGGTGGACCATTACCAATTGC
TGCTGCCTGAAGGTGTCGCGCAACTGCAAGCGGCCCTGTTTCCCTCTGTTTCCGTTAATGTGATAAGTGAGTCATGA

Upstream 100 bases:

>100_bases
TAAGGCCGGCATTTTCCCTGAATGGGGAGTGTTGCTAAAGCATGTCGTCATTACAACCCTACCGGGATCCTGGCAAATGT
GAGGCGTTCATAGAGTAAAA

Downstream 100 bases:

>100_bases
TGCAAGCTAATTTACTGCCTTTGGTTATTCATCCTGAAGTGAAGGCCGCCCTGGAAAGTCGCCACGCGGTGGTTGCGCTG
GAGTCAAACGTCATTACCCA

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Tyrocidine synthase III; ATP-dependent asparagine adenylase; AsnA; Asparagine activase; ATP-dependent glutamine adenylase; GlnA; Glutamine activase; ATP-dependent tyrosine adenylase; TyrA; Tyrosine activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 1278; Mature: 1278

Protein sequence:

>1278_residues
MDISAGLFEQLAQHYSQQPEAIAVQDADSVLSYRDFCHHVFSISSCLRQWINTDRVCIGLFCEPSTTLVSGAWGILASGY
AYLPLAPEYPDERLRYMITDSEVKVILCQYHLKEKLQTLIGPDVTIITDNDIPYLSDLPKAVFDIADSSDAARLAYVIYT
SGSSGKPKGVMVSYPNISRHMYYLSHRFAFGAQSKILQKTPMSFDAAQWEILAPAMGCSLVIAPKDCYRDPDMMVATLLR
HQITSLQCVPTLLQALVEQPLLQDCQALTQVFCGGEILTRNLAKQFFQCLPQARLINLYGPTECTINASVHEVEKEALEQ
SPDAVSIGRPVEDTAFYVLDAHRQPVAEGEKGELYISGVQVANGYLLRPELTAERFLTNPFNSAAEHARMYRTGDVVYRD
SLGCYHFAGRADNQIKLRGYRIELDEIRLAIERHLWVKRAAVMVNEDERTHYQNLIACVELDSQHAALMDQGVHGEHHQS
KASRQQVKAQLSNAGCRSEDECRALPAIALAGAQATAQQNYRAFSRKSYRFFEGTTRVTEAQLLSILGRSPRAMLASDLQ
ALSVEDFGALLRNFGQFASEKRLLPKYAYASPGALYSVQMYLELHRMFGWPAGIYYYHPVNHRLYCVCELPEQATGSLEI
HFIGKRAAIDQVYQNNIQEVLEMEAGHMLGLFDELLPEYGLQAASGAQPGALPQWYDGAATDYYFGDFRIQPANMEAVVD
HPEFFVQVHAQGVADMSPGLYHYRQGSLHFMDEEILARHHVIAINQQVYQRAGFGIMLVNNHADAQGHYIMLGRALHRLQ
ANPLGLGMMSAGYSSKSGHDLPAAKAMRTLLTRHGLPMQSCYFCIGGPLSQSQLCHDGMDEDRVHMQGPTEMLKADLAAQ
LPQYMIPNRVLVMDKLPLMANGKVDQQALNRMYACQLNTEKPIVVPEGELQQRLAEIWCRVMKWERVSADDDFFESGGNS
LTAVMFINQVNKALDIKLPMQILFQTPNIVALADWIERNAYLAPQLSRLVPFNRQQAPAIFCWPGLGGYPLSLKALGESL
SQARAFYGVQALGINEGELPLESIQQMAAADIAQIRRLQPQGPYTLWGYSFGARVAFEAAYQLEAEGQVVEELYLIAPGS
PKTQFDREQEGNQQVNFTNPVFVAILFSVFARQVEGPLLERCLAECREEGDFVRFICRCFPQLQVELVARIIEIVKQTYA
FGYNFEELQQRQVRAPVTVIKAAGDHYSQLENSPALLANPLRVISLAVDHYQLLLPEGVAQLQAALFPSVSVNVISES

Sequences:

>Translated_1278_residues
MDISAGLFEQLAQHYSQQPEAIAVQDADSVLSYRDFCHHVFSISSCLRQWINTDRVCIGLFCEPSTTLVSGAWGILASGY
AYLPLAPEYPDERLRYMITDSEVKVILCQYHLKEKLQTLIGPDVTIITDNDIPYLSDLPKAVFDIADSSDAARLAYVIYT
SGSSGKPKGVMVSYPNISRHMYYLSHRFAFGAQSKILQKTPMSFDAAQWEILAPAMGCSLVIAPKDCYRDPDMMVATLLR
HQITSLQCVPTLLQALVEQPLLQDCQALTQVFCGGEILTRNLAKQFFQCLPQARLINLYGPTECTINASVHEVEKEALEQ
SPDAVSIGRPVEDTAFYVLDAHRQPVAEGEKGELYISGVQVANGYLLRPELTAERFLTNPFNSAAEHARMYRTGDVVYRD
SLGCYHFAGRADNQIKLRGYRIELDEIRLAIERHLWVKRAAVMVNEDERTHYQNLIACVELDSQHAALMDQGVHGEHHQS
KASRQQVKAQLSNAGCRSEDECRALPAIALAGAQATAQQNYRAFSRKSYRFFEGTTRVTEAQLLSILGRSPRAMLASDLQ
ALSVEDFGALLRNFGQFASEKRLLPKYAYASPGALYSVQMYLELHRMFGWPAGIYYYHPVNHRLYCVCELPEQATGSLEI
HFIGKRAAIDQVYQNNIQEVLEMEAGHMLGLFDELLPEYGLQAASGAQPGALPQWYDGAATDYYFGDFRIQPANMEAVVD
HPEFFVQVHAQGVADMSPGLYHYRQGSLHFMDEEILARHHVIAINQQVYQRAGFGIMLVNNHADAQGHYIMLGRALHRLQ
ANPLGLGMMSAGYSSKSGHDLPAAKAMRTLLTRHGLPMQSCYFCIGGPLSQSQLCHDGMDEDRVHMQGPTEMLKADLAAQ
LPQYMIPNRVLVMDKLPLMANGKVDQQALNRMYACQLNTEKPIVVPEGELQQRLAEIWCRVMKWERVSADDDFFESGGNS
LTAVMFINQVNKALDIKLPMQILFQTPNIVALADWIERNAYLAPQLSRLVPFNRQQAPAIFCWPGLGGYPLSLKALGESL
SQARAFYGVQALGINEGELPLESIQQMAAADIAQIRRLQPQGPYTLWGYSFGARVAFEAAYQLEAEGQVVEELYLIAPGS
PKTQFDREQEGNQQVNFTNPVFVAILFSVFARQVEGPLLERCLAECREEGDFVRFICRCFPQLQVELVARIIEIVKQTYA
FGYNFEELQQRQVRAPVTVIKAAGDHYSQLENSPALLANPLRVISLAVDHYQLLLPEGVAQLQAALFPSVSVNVISES
>Mature_1278_residues
MDISAGLFEQLAQHYSQQPEAIAVQDADSVLSYRDFCHHVFSISSCLRQWINTDRVCIGLFCEPSTTLVSGAWGILASGY
AYLPLAPEYPDERLRYMITDSEVKVILCQYHLKEKLQTLIGPDVTIITDNDIPYLSDLPKAVFDIADSSDAARLAYVIYT
SGSSGKPKGVMVSYPNISRHMYYLSHRFAFGAQSKILQKTPMSFDAAQWEILAPAMGCSLVIAPKDCYRDPDMMVATLLR
HQITSLQCVPTLLQALVEQPLLQDCQALTQVFCGGEILTRNLAKQFFQCLPQARLINLYGPTECTINASVHEVEKEALEQ
SPDAVSIGRPVEDTAFYVLDAHRQPVAEGEKGELYISGVQVANGYLLRPELTAERFLTNPFNSAAEHARMYRTGDVVYRD
SLGCYHFAGRADNQIKLRGYRIELDEIRLAIERHLWVKRAAVMVNEDERTHYQNLIACVELDSQHAALMDQGVHGEHHQS
KASRQQVKAQLSNAGCRSEDECRALPAIALAGAQATAQQNYRAFSRKSYRFFEGTTRVTEAQLLSILGRSPRAMLASDLQ
ALSVEDFGALLRNFGQFASEKRLLPKYAYASPGALYSVQMYLELHRMFGWPAGIYYYHPVNHRLYCVCELPEQATGSLEI
HFIGKRAAIDQVYQNNIQEVLEMEAGHMLGLFDELLPEYGLQAASGAQPGALPQWYDGAATDYYFGDFRIQPANMEAVVD
HPEFFVQVHAQGVADMSPGLYHYRQGSLHFMDEEILARHHVIAINQQVYQRAGFGIMLVNNHADAQGHYIMLGRALHRLQ
ANPLGLGMMSAGYSSKSGHDLPAAKAMRTLLTRHGLPMQSCYFCIGGPLSQSQLCHDGMDEDRVHMQGPTEMLKADLAAQ
LPQYMIPNRVLVMDKLPLMANGKVDQQALNRMYACQLNTEKPIVVPEGELQQRLAEIWCRVMKWERVSADDDFFESGGNS
LTAVMFINQVNKALDIKLPMQILFQTPNIVALADWIERNAYLAPQLSRLVPFNRQQAPAIFCWPGLGGYPLSLKALGESL
SQARAFYGVQALGINEGELPLESIQQMAAADIAQIRRLQPQGPYTLWGYSFGARVAFEAAYQLEAEGQVVEELYLIAPGS
PKTQFDREQEGNQQVNFTNPVFVAILFSVFARQVEGPLLERCLAECREEGDFVRFICRCFPQLQVELVARIIEIVKQTYA
FGYNFEELQQRQVRAPVTVIKAAGDHYSQLENSPALLANPLRVISLAVDHYQLLLPEGVAQLQAALFPSVSVNVISES

Specific function: Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=438, Percent_Identity=25.3424657534247, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI187761345, Length=502, Percent_Identity=23.5059760956175, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI187761343, Length=502, Percent_Identity=23.5059760956175, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI38505220, Length=411, Percent_Identity=23.1143552311436, Blast_Score=79, Evalue=4e-14,
Organism=Escherichia coli, GI1786801, Length=435, Percent_Identity=35.632183908046, Blast_Score=253, Evalue=5e-68,
Organism=Escherichia coli, GI145693145, Length=506, Percent_Identity=24.5059288537549, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1788107, Length=489, Percent_Identity=22.4948875255624, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786810, Length=318, Percent_Identity=26.7295597484277, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17531443, Length=490, Percent_Identity=25.7142857142857, Blast_Score=104, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI32564422, Length=286, Percent_Identity=27.6223776223776, Blast_Score=85, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32564420, Length=286, Percent_Identity=27.6223776223776, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17556356, Length=429, Percent_Identity=26.1072261072261, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17550940, Length=276, Percent_Identity=23.9130434782609, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560308, Length=450, Percent_Identity=22.6666666666667, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560140, Length=471, Percent_Identity=21.2314225053079, Blast_Score=74, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319591, Length=316, Percent_Identity=26.8987341772152, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24648676, Length=426, Percent_Identity=31.2206572769953, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24582852, Length=323, Percent_Identity=26.0061919504644, Blast_Score=78, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24656500, Length=491, Percent_Identity=23.6252545824847, Blast_Score=77, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648260, Length=396, Percent_Identity=21.969696969697, Blast_Score=73, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 142901; Mature: 142901

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDISAGLFEQLAQHYSQQPEAIAVQDADSVLSYRDFCHHVFSISSCLRQWINTDRVCIGL
CCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
FCEPSTTLVSGAWGILASGYAYLPLAPEYPDERLRYMITDSEVKVILCQYHLKEKLQTLI
EECCCCHHHHCCHHHHHCCEEEECCCCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHHH
GPDVTIITDNDIPYLSDLPKAVFDIADSSDAARLAYVIYTSGSSGKPKGVMVSYPNISRH
CCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCHHH
MYYLSHRFAFGAQSKILQKTPMSFDAAQWEILAPAMGCSLVIAPKDCYRDPDMMVATLLR
HHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEECCCCCCEEEEECHHHCCCHHHHHHHHHH
HQITSLQCVPTLLQALVEQPLLQDCQALTQVFCGGEILTRNLAKQFFQCLPQARLINLYG
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEEEEC
PTECTINASVHEVEKEALEQSPDAVSIGRPVEDTAFYVLDAHRQPVAEGEKGELYISGVQ
CCEEEEECHHHHHHHHHHHCCCCCEECCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEE
VANGYLLRPELTAERFLTNPFNSAAEHARMYRTGDVVYRDSLGCYHFAGRADNQIKLRGY
EECCEEECCCCCHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCEEEEEEE
RIELDEIRLAIERHLWVKRAAVMVNEDERTHYQNLIACVELDSQHAALMDQGVHGEHHQS
EEEHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHEEEEECCHHHHHHHCCCCCCHHHH
KASRQQVKAQLSNAGCRSEDECRALPAIALAGAQATAQQNYRAFSRKSYRFFEGTTRVTE
HHHHHHHHHHHHCCCCCCCHHHHHCCHHHHCCCHHHHHHHHHHHHCCCCEEECCCCHHHH
AQLLSILGRSPRAMLASDLQALSVEDFGALLRNFGQFASEKRLLPKYAYASPGALYSVQM
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHH
YLELHRMFGWPAGIYYYHPVNHRLYCVCELPEQATGSLEIHFIGKRAAIDQVYQNNIQEV
HHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
LEMEAGHMLGLFDELLPEYGLQAASGAQPGALPQWYDGAATDYYFGDFRIQPANMEAVVD
HHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCEEECCCCCEEEEC
HPEFFVQVHAQGVADMSPGLYHYRQGSLHFMDEEILARHHVIAINQQVYQRAGFGIMLVN
CCHHEEEEECCCCCCCCCCCEEECCCCCEECCHHHHHHHHEEEECHHHHHHCCCEEEEEE
NHADAQGHYIMLGRALHRLQANPLGLGMMSAGYSSKSGHDLPAAKAMRTLLTRHGLPMQS
CCCCCCCCEEEHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHH
CYFCIGGPLSQSQLCHDGMDEDRVHMQGPTEMLKADLAAQLPQYMIPNRVLVMDKLPLMA
HHEEECCCCCHHHHHHCCCCCCCEEECCHHHHHHHHHHHHCHHHHCCCEEEEEECCCCCC
NGKVDQQALNRMYACQLNTEKPIVVPEGELQQRLAEIWCRVMKWERVSADDDFFESGGNS
CCCCCHHHHCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
LTAVMFINQVNKALDIKLPMQILFQTPNIVALADWIERNAYLAPQLSRLVPFNRQQAPAI
EEEEEEEHHHCHHEECCCCHHHHCCCCCEEEEHHHHHCCCCCCCHHHHHCCCCCCCCCEE
FCWPGLGGYPLSLKALGESLSQARAFYGVQALGINEGELPLESIQQMAAADIAQIRRLQP
EECCCCCCCCEEHHHHHHHHHHHHHHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCC
QGPYTLWGYSFGARVAFEAAYQLEAEGQVVEELYLIAPGSPKTQFDREQEGNQQVNFTNP
CCCEEEEEECCCCCEEEHHHHEECCCCCEEEEEEEECCCCCCCCCCHHHCCCCEECCCCH
VFVAILFSVFARQVEGPLLERCLAECREEGDFVRFICRCFPQLQVELVARIIEIVKQTYA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGYNFEELQQRQVRAPVTVIKAAGDHYSQLENSPALLANPLRVISLAVDHYQLLLPEGVA
CCCCHHHHHHHHHHCCEEEEEECCCHHHHHCCCCCHHHCHHHHHHHHHHHHHHHHHHHHH
QLQAALFPSVSVNVISES
HHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MDISAGLFEQLAQHYSQQPEAIAVQDADSVLSYRDFCHHVFSISSCLRQWINTDRVCIGL
CCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
FCEPSTTLVSGAWGILASGYAYLPLAPEYPDERLRYMITDSEVKVILCQYHLKEKLQTLI
EECCCCHHHHCCHHHHHCCEEEECCCCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHHH
GPDVTIITDNDIPYLSDLPKAVFDIADSSDAARLAYVIYTSGSSGKPKGVMVSYPNISRH
CCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCHHH
MYYLSHRFAFGAQSKILQKTPMSFDAAQWEILAPAMGCSLVIAPKDCYRDPDMMVATLLR
HHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEECCCCCCEEEEECHHHCCCHHHHHHHHHH
HQITSLQCVPTLLQALVEQPLLQDCQALTQVFCGGEILTRNLAKQFFQCLPQARLINLYG
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEEEEC
PTECTINASVHEVEKEALEQSPDAVSIGRPVEDTAFYVLDAHRQPVAEGEKGELYISGVQ
CCEEEEECHHHHHHHHHHHCCCCCEECCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEE
VANGYLLRPELTAERFLTNPFNSAAEHARMYRTGDVVYRDSLGCYHFAGRADNQIKLRGY
EECCEEECCCCCHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCEEEEEEE
RIELDEIRLAIERHLWVKRAAVMVNEDERTHYQNLIACVELDSQHAALMDQGVHGEHHQS
EEEHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHEEEEECCHHHHHHHCCCCCCHHHH
KASRQQVKAQLSNAGCRSEDECRALPAIALAGAQATAQQNYRAFSRKSYRFFEGTTRVTE
HHHHHHHHHHHHCCCCCCCHHHHHCCHHHHCCCHHHHHHHHHHHHCCCCEEECCCCHHHH
AQLLSILGRSPRAMLASDLQALSVEDFGALLRNFGQFASEKRLLPKYAYASPGALYSVQM
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHH
YLELHRMFGWPAGIYYYHPVNHRLYCVCELPEQATGSLEIHFIGKRAAIDQVYQNNIQEV
HHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
LEMEAGHMLGLFDELLPEYGLQAASGAQPGALPQWYDGAATDYYFGDFRIQPANMEAVVD
HHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCEEECCCCCEEEEC
HPEFFVQVHAQGVADMSPGLYHYRQGSLHFMDEEILARHHVIAINQQVYQRAGFGIMLVN
CCHHEEEEECCCCCCCCCCCEEECCCCCEECCHHHHHHHHEEEECHHHHHHCCCEEEEEE
NHADAQGHYIMLGRALHRLQANPLGLGMMSAGYSSKSGHDLPAAKAMRTLLTRHGLPMQS
CCCCCCCCEEEHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHH
CYFCIGGPLSQSQLCHDGMDEDRVHMQGPTEMLKADLAAQLPQYMIPNRVLVMDKLPLMA
HHEEECCCCCHHHHHHCCCCCCCEEECCHHHHHHHHHHHHCHHHHCCCEEEEEECCCCCC
NGKVDQQALNRMYACQLNTEKPIVVPEGELQQRLAEIWCRVMKWERVSADDDFFESGGNS
CCCCCHHHHCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
LTAVMFINQVNKALDIKLPMQILFQTPNIVALADWIERNAYLAPQLSRLVPFNRQQAPAI
EEEEEEEHHHCHHEECCCCHHHHCCCCCEEEEHHHHHCCCCCCCHHHHHCCCCCCCCCEE
FCWPGLGGYPLSLKALGESLSQARAFYGVQALGINEGELPLESIQQMAAADIAQIRRLQP
EECCCCCCCCEEHHHHHHHHHHHHHHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCC
QGPYTLWGYSFGARVAFEAAYQLEAEGQVVEELYLIAPGSPKTQFDREQEGNQQVNFTNP
CCCEEEEEECCCCCEEEHHHHEECCCCCEEEEEEEECCCCCCCCCCHHHCCCCEECCCCH
VFVAILFSVFARQVEGPLLERCLAECREEGDFVRFICRCFPQLQVELVARIIEIVKQTYA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGYNFEELQQRQVRAPVTVIKAAGDHYSQLENSPALLANPLRVISLAVDHYQLLLPEGVA
CCCCHHHHHHHHHHCCEEEEEECCCHHHHHCCCCCHHHCHHHHHHHHHHHHHHHHHHHHH
QLQAALFPSVSVNVISES
HHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352938; 10801488 [H]