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The map label for this gene is ppaX [H]

Identifier: 157369940

GI number: 157369940

Start: 1857693

End: 1858388

Strand: Direct

Name: ppaX [H]

Synonym: Spro_1697

Alternate gene names: 157369940

Gene position: 1857693-1858388 (Clockwise)

Preceding gene: 157369939

Following gene: 157369941

Centisome position: 34.09

GC content: 54.45

Gene sequence:

>696_bases
ATGAAATCTGAACTCAGAGTCATTATGTTTGACCTTGACGGCACCCTGTTTGATACGGCGAGAGCGATAGTCTCTGCCTT
TCGTGCCACCTTTCAACAACTGCAATTACCACAGCCGGCCGAGGATGAGCTGATTCGTGAAACGATAGGCCTGCCGTTGG
AGCGTGCCTTTGCCCAATTGCTGTCTCAGGAGGCCGATAGCCGGACAGTAACCGACTGCGTGGCGGAGTATCAACGGCAG
TTTCAGACGCTGATTTTACCCATGGCGGCATCGCTGTTATTTCCTGGCGTCGCTGCGGGCCTGCAACAGTTGAAAGGAGC
GGGTTTTCATCTGGCGGTGACCACTAATAAGTTCGCACGCAGTGCAAATTCGCTATTGGCGGCGGCGGGCATTGCCCCAT
TGTTTGATGTGGTGGTTTGCGCTGACCAGGTAACGGAGAAAAAACCGGCGCCGGAGTCTGGCAACAAAATCCTGGATCAC
TATCAGGTCAGGGCGATCGATGCGGTGATGGTGGGGGATACTACGCACGACATATTGATGGCTCATCAGGTTGGCTGTCA
GGTGATCGCGGTGGATTATGGTATTCAAAATCGTCAGGTACTGGCCGCGGCCGAGCCCAGCATTATTGTAAGCTCTTTTG
CCGCCGTGGTTGACTGGTGCCGTCACAGAGACGTTAGTCGCGTAGCAGCAGGCTAG

Upstream 100 bases:

>100_bases
CCGATGACTGGCAGGCGCAGGTTTATCGCCCGGAAATAGAAAATAAAAAAGACTGTTTAATTAAAGTCCCTAATTACTGA
CCCTCAAGAAGGTGACATCT

Downstream 100 bases:

>100_bases
CAAAAGCAAAAGCATTACGGGTTATTCAGGGCCGCAGACAGCGCTATTTCTTAATGGTGAAAGTTTACGGGCGATAAATA
TCGCCATGCTTACGCCATTA

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKSELRVIMFDLDGTLFDTARAIVSAFRATFQQLQLPQPAEDELIRETIGLPLERAFAQLLSQEADSRTVTDCVAEYQRQ
FQTLILPMAASLLFPGVAAGLQQLKGAGFHLAVTTNKFARSANSLLAAAGIAPLFDVVVCADQVTEKKPAPESGNKILDH
YQVRAIDAVMVGDTTHDILMAHQVGCQVIAVDYGIQNRQVLAAAEPSIIVSSFAAVVDWCRHRDVSRVAAG

Sequences:

>Translated_231_residues
MKSELRVIMFDLDGTLFDTARAIVSAFRATFQQLQLPQPAEDELIRETIGLPLERAFAQLLSQEADSRTVTDCVAEYQRQ
FQTLILPMAASLLFPGVAAGLQQLKGAGFHLAVTTNKFARSANSLLAAAGIAPLFDVVVCADQVTEKKPAPESGNKILDH
YQVRAIDAVMVGDTTHDILMAHQVGCQVIAVDYGIQNRQVLAAAEPSIIVSSFAAVVDWCRHRDVSRVAAG
>Mature_231_residues
MKSELRVIMFDLDGTLFDTARAIVSAFRATFQQLQLPQPAEDELIRETIGLPLERAFAQLLSQEADSRTVTDCVAEYQRQ
FQTLILPMAASLLFPGVAAGLQQLKGAGFHLAVTTNKFARSANSLLAAAGIAPLFDVVVCADQVTEKKPAPESGNKILDH
YQVRAIDAVMVGDTTHDILMAHQVGCQVIAVDYGIQNRQVLAAAEPSIIVSSFAAVVDWCRHRDVSRVAAG

Specific function: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool [H]

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. PpaX family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=229, Percent_Identity=29.6943231441048, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 25007; Mature: 25007

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSELRVIMFDLDGTLFDTARAIVSAFRATFQQLQLPQPAEDELIRETIGLPLERAFAQL
CCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHH
LSQEADSRTVTDCVAEYQRQFQTLILPMAASLLFPGVAAGLQQLKGAGFHLAVTTNKFAR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHH
SANSLLAAAGIAPLFDVVVCADQVTEKKPAPESGNKILDHYQVRAIDAVMVGDTTHDILM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEEEEECCCHHHHHH
AHQVGCQVIAVDYGIQNRQVLAAAEPSIIVSSFAAVVDWCRHRDVSRVAAG
HHHHCCEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHCCC
>Mature Secondary Structure
MKSELRVIMFDLDGTLFDTARAIVSAFRATFQQLQLPQPAEDELIRETIGLPLERAFAQL
CCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHH
LSQEADSRTVTDCVAEYQRQFQTLILPMAASLLFPGVAAGLQQLKGAGFHLAVTTNKFAR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHH
SANSLLAAAGIAPLFDVVVCADQVTEKKPAPESGNKILDHYQVRAIDAVMVGDTTHDILM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEEEEECCCHHHHHH
AHQVGCQVIAVDYGIQNRQVLAAAEPSIIVSSFAAVVDWCRHRDVSRVAAG
HHHHCCEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]