The gene/protein map for NC_009832 is currently unavailable.
Definition Serratia proteamaculans 568 chromosome, complete genome.
Accession NC_009832
Length 5,448,853

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The map label for this gene is serS

Identifier: 157369929

GI number: 157369929

Start: 1847661

End: 1848953

Strand: Direct

Name: serS

Synonym: Spro_1686

Alternate gene names: 157369929

Gene position: 1847661-1848953 (Clockwise)

Preceding gene: 157369928

Following gene: 157369930

Centisome position: 33.91

GC content: 55.76

Gene sequence:

>1293_bases
ATGCTCGATCCCAATCTGCTGCGTAATGAGCTAGACGCAGTCGCCGTCAAACTGGCTCGCCGAGGCTTTAAACTCGATCT
GGATCTGCTGCGTTCTCAAGAAGAGCGTCGTAAAGTTCTGCAGGTAGAAACCGAAACGCTGCAGGCAGAACGTAACTCCC
GATCGAAATCCATCGGCGCGGCTAAAGCGCGCGGGGAAGACATTGAGCCGCTGCGTCGCGAAGTAAACGAACTGGGTGAC
AAGCTGGACACGGCCAAGGCCGCGCTGGATCAGCTGCAGGCTGAAATCCGTGACTATGCGTTGGCGATCCCGAACCTGCC
TGACGATGAAGTACCAGACGGTAAAGACGACAGCGATAACCTGGAAGTCAGCCGCTGGGGCGAGCCGCGCCAGTATGATT
TCGCGGTACGCGATCACGTCGATCTGGGCGAAATGGCCGGTGGTCTGGACTTTGCCGCTGCGGTAAAACTGACCGGTTCA
CGCTTTGTGGTGATGAAAGGGCAAATTGCCCGTATGCACCGCGCGTTGTCCCAGTTCATGCTGGATCTGCATACCGAACA
ACACGGCTACCAGGAAACTTACGTTCCTTACCTGGTTAACCATGCCACACTGTTCGGTACCGGCCAGTTGCCGAAATTTG
GTGAAGACTTGTTCCACACCAAACCGCTGGAAGAAGAATCCGACAGCAGCAACTACGCACTGATCCCAACCGCAGAAGTG
CCATTGACCAACCTGGTGCGCGACGAGATCCTGGAAGAGGAATCTCTGCCACTGAAGATGACTGCGCATACGCCTTGTTT
CCGTGCCGAAGCCGGTTCTTATGGCCGTGACACCCGTGGTTTGATCCGCATGCACCAGTTCGACAAAGTTGAGATGGTGC
AGATCGTCCGTCCGGAAGACTCGATGACTACGCTGGAAGAGCTGACCGGTCATGCAGAGAAAGTGCTGCAGTTGCTGAAC
CTGCCATACCGTAAAATGTTGCTGTGTACCGGTGACATGGGCGCAGGCTCTTGCAAGACCTACGATCTGGAAGTGTGGCT
GCCGGCGCAGGACACTTACCGTGAGATCTCATCCTGCTCCAACATGTGGGATTACCAGGCACGCCGCATGCAGGCCCGTT
GCCGCAGCAAAACCGAGAAGAAGCCGCGCCTGGTGCATACGCTGAACGGTTCTGGTCTGGCAGTAGGTCGTACGCTGGTA
GCAGTGCTGGAAAACTACCAGCAGGCTGATGGCCGTATTCAGGTTCCGGAAGTATTACGCCCATATATGGGTGGCCTGGA
ATATATCGGTTAA

Upstream 100 bases:

>100_bases
GCGGTAAGGTTAGCGGGTATCACTCTTCCTTTATACGGCTATAAATTCAGCCGAATAAAACATCAAATTTTCTTTCAATA
ACAATAAGCACAGGATTAGC

Downstream 100 bases:

>100_bases
CGAGTTAGTTATGTTACGAAAAGCGCCTGCGGGCGCTTTTTTTATAAGAAAATTATTACCCCTTTGTTCGAAAGCCTTTT
TTCTTTCAGATACTTCCCCC

Product: seryl-tRNA synthetase

Products: NA

Alternate protein names: Serine--tRNA ligase; SerRS; Seryl-tRNA(Ser/Sec) synthetase

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MLDPNLLRNELDAVAVKLARRGFKLDLDLLRSQEERRKVLQVETETLQAERNSRSKSIGAAKARGEDIEPLRREVNELGD
KLDTAKAALDQLQAEIRDYALAIPNLPDDEVPDGKDDSDNLEVSRWGEPRQYDFAVRDHVDLGEMAGGLDFAAAVKLTGS
RFVVMKGQIARMHRALSQFMLDLHTEQHGYQETYVPYLVNHATLFGTGQLPKFGEDLFHTKPLEEESDSSNYALIPTAEV
PLTNLVRDEILEEESLPLKMTAHTPCFRAEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMTTLEELTGHAEKVLQLLN
LPYRKMLLCTGDMGAGSCKTYDLEVWLPAQDTYREISSCSNMWDYQARRMQARCRSKTEKKPRLVHTLNGSGLAVGRTLV
AVLENYQQADGRIQVPEVLRPYMGGLEYIG

Sequences:

>Translated_430_residues
MLDPNLLRNELDAVAVKLARRGFKLDLDLLRSQEERRKVLQVETETLQAERNSRSKSIGAAKARGEDIEPLRREVNELGD
KLDTAKAALDQLQAEIRDYALAIPNLPDDEVPDGKDDSDNLEVSRWGEPRQYDFAVRDHVDLGEMAGGLDFAAAVKLTGS
RFVVMKGQIARMHRALSQFMLDLHTEQHGYQETYVPYLVNHATLFGTGQLPKFGEDLFHTKPLEEESDSSNYALIPTAEV
PLTNLVRDEILEEESLPLKMTAHTPCFRAEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMTTLEELTGHAEKVLQLLN
LPYRKMLLCTGDMGAGSCKTYDLEVWLPAQDTYREISSCSNMWDYQARRMQARCRSKTEKKPRLVHTLNGSGLAVGRTLV
AVLENYQQADGRIQVPEVLRPYMGGLEYIG
>Mature_430_residues
MLDPNLLRNELDAVAVKLARRGFKLDLDLLRSQEERRKVLQVETETLQAERNSRSKSIGAAKARGEDIEPLRREVNELGD
KLDTAKAALDQLQAEIRDYALAIPNLPDDEVPDGKDDSDNLEVSRWGEPRQYDFAVRDHVDLGEMAGGLDFAAAVKLTGS
RFVVMKGQIARMHRALSQFMLDLHTEQHGYQETYVPYLVNHATLFGTGQLPKFGEDLFHTKPLEEESDSSNYALIPTAEV
PLTNLVRDEILEEESLPLKMTAHTPCFRAEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMTTLEELTGHAEKVLQLLN
LPYRKMLLCTGDMGAGSCKTYDLEVWLPAQDTYREISSCSNMWDYQARRMQARCRSKTEKKPRLVHTLNGSGLAVGRTLV
AVLENYQQADGRIQVPEVLRPYMGGLEYIG

Specific function: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)

COG id: COG0172

COG function: function code J; Seryl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily

Homologues:

Organism=Homo sapiens, GI16306548, Length=375, Percent_Identity=36, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI8923421, Length=418, Percent_Identity=28.2296650717703, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI225579074, Length=353, Percent_Identity=29.4617563739377, Blast_Score=152, Evalue=8e-37,
Organism=Escherichia coli, GI1787120, Length=430, Percent_Identity=84.6511627906977, Blast_Score=764, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539260, Length=334, Percent_Identity=33.8323353293413, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17542084, Length=334, Percent_Identity=29.0419161676647, Blast_Score=144, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6320226, Length=404, Percent_Identity=30.4455445544554, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6321799, Length=388, Percent_Identity=30.6701030927835, Blast_Score=186, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24581334, Length=343, Percent_Identity=34.402332361516, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI17737985, Length=370, Percent_Identity=32.7027027027027, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYS_SERP5 (A8GCF0)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477918.1
- ProteinModelPortal:   A8GCF0
- SMR:   A8GCF0
- STRING:   A8GCF0
- GeneID:   5604213
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_1686
- eggNOG:   COG0172
- HOGENOM:   HBG629391
- OMA:   AHWDLGP
- ProtClustDB:   PRK05431
- BioCyc:   SPRO399741:SPRO_1686-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00176
- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR002317
- InterPro:   IPR015866
- InterPro:   IPR010978
- Gene3D:   G3DSA:1.10.287.40
- PANTHER:   PTHR11778
- PIRSF:   PIRSF001529
- PRINTS:   PR00981
- TIGRFAMs:   TIGR00414

Pfam domain/function: PF02403 Seryl_tRNA_N; PF00587 tRNA-synt_2b; SSF46589 tRNA_binding_arm

EC number: =6.1.1.11

Molecular weight: Translated: 48580; Mature: 48580

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: BINDING 291-291 BINDING 391-391

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MLDPNLLRNELDAVAVKLARRGFKLDLDLLRSQEERRKVLQVETETLQAERNSRSKSIGA
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHCCC
AKARGEDIEPLRREVNELGDKLDTAKAALDQLQAEIRDYALAIPNLPDDEVPDGKDDSDN
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCC
LEVSRWGEPRQYDFAVRDHVDLGEMAGGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFM
CEEECCCCCCCCCCHHHCCCCHHHHCCCCCHHHHEEECCCEEEEECCHHHHHHHHHHHHH
LDLHTEQHGYQETYVPYLVNHATLFGTGQLPKFGEDLFHTKPLEEESDSSNYALIPTAEV
HHHHHHHCCCCHHHHHHHHHCEEEEECCCCCHHHHHHHCCCCCCCCCCCCCEEEEECCCC
PLTNLVRDEILEEESLPLKMTAHTPCFRAEAGSYGRDTRGLIRMHQFDKVEMVQIVRPED
CHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCC
SMTTLEELTGHAEKVLQLLNLPYRKMLLCTGDMGAGSCKTYDLEVWLPAQDTYREISSCS
HHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCCCEEEEEEEEECCHHHHHHHHHHH
NMWDYQARRMQARCRSKTEKKPRLVHTLNGSGLAVGRTLVAVLENYQQADGRIQVPEVLR
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCEECHHHHH
PYMGGLEYIG
HHHCCCCCCC
>Mature Secondary Structure
MLDPNLLRNELDAVAVKLARRGFKLDLDLLRSQEERRKVLQVETETLQAERNSRSKSIGA
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHCCC
AKARGEDIEPLRREVNELGDKLDTAKAALDQLQAEIRDYALAIPNLPDDEVPDGKDDSDN
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCC
LEVSRWGEPRQYDFAVRDHVDLGEMAGGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFM
CEEECCCCCCCCCCHHHCCCCHHHHCCCCCHHHHEEECCCEEEEECCHHHHHHHHHHHHH
LDLHTEQHGYQETYVPYLVNHATLFGTGQLPKFGEDLFHTKPLEEESDSSNYALIPTAEV
HHHHHHHCCCCHHHHHHHHHCEEEEECCCCCHHHHHHHCCCCCCCCCCCCCEEEEECCCC
PLTNLVRDEILEEESLPLKMTAHTPCFRAEAGSYGRDTRGLIRMHQFDKVEMVQIVRPED
CHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCC
SMTTLEELTGHAEKVLQLLNLPYRKMLLCTGDMGAGSCKTYDLEVWLPAQDTYREISSCS
HHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCCCEEEEEEEEECCHHHHHHHHHHH
NMWDYQARRMQARCRSKTEKKPRLVHTLNGSGLAVGRTLVAVLENYQQADGRIQVPEVLR
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCEECHHHHH
PYMGGLEYIG
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA