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The map label for this gene is pcbC [H]

Identifier: 157369868

GI number: 157369868

Start: 1779598

End: 1780617

Strand: Direct

Name: pcbC [H]

Synonym: Spro_1625

Alternate gene names: 157369868

Gene position: 1779598-1780617 (Clockwise)

Preceding gene: 157369863

Following gene: 157369871

Centisome position: 32.66

GC content: 61.08

Gene sequence:

>1020_bases
ATGACGCCACCACTGACGTTGAAGACGCTGCCGCAACTGAGTCTTTCGCAGCTTGACGGCGACCGGCGACAGCGGCAGGC
ATTTCTTGACGGGTTGCGTGAGGCCGCCCGTGACGTAGGTTTTTTCTATCTGCGCGGACACGGCGTGGATAACAGGTTGA
ATGCTCAACTGCAGCAGCATGCCCGGCAGTTTTTTGCGCTGCCGGAAGCCGACAAACTGGCGGTGCAGATGGTGCATTCG
CCGCATTTCCGCGGTTATAACCGAGCGGCGGCCGAACTGACGCGCGGACAGCCGGACTGGCGCGAACAGTTCGATATCGG
CGCGGAGCGTCCTGCGTTGCAACTGGCCAATGAGACTCCGCGATGGGCGCGTTTACAGGGGCCGAATCAATGGCCTGAGG
CGCTACCCGCACTCAAACCGCTGCTGTTGCAGTGGCAGCAGGCGATGACCGCCATGTCGCTGCGACTGTTGCGCGCCTTC
GCGCTGGCGCTTTCGTTGCCGGAGCAGGCATTTGACTCGCTCTACGGCGATAAACCCAATGAACATATCAAACTGATCCG
TTACCCGGGGCGGGATGCTACCGACAGCGGGCAAGGGGTGGGCGCCCATAAAGACTCCGGTTTTCTCAGTTTTTTGCTGC
AGGACCGGCAGAAAGGCCTGCAGGTTGAAGTTGACGAAGGGCGCTGGGTTGACGCCGAACCGCTTGAAGACAGTTTTGTA
GTCAACATCGGTGAACTGCTGGAGTTGGCAACCAACGGCTATCTGCGTGCCACGGTGCACCGGGTAGAGACGCCGCCGGC
GGGCAGCGAGCGCCTGTCGATTGCCTTCTTCCTCGGGGCACGGCTGGACGCCGTGGTGCCGCTGTATCAGCTCCCTGCGC
ATCTGGCGGCCGAGGCGCGTGGTCCAGCCAGCGATCCGCATAATCCGCTGTTGCGTGACGTGGGCTTTAACTACCTGAAA
GGACGCATTCGCTCACATCCCGACGTGGCGCAGCGCTATTATCAGGACGTTGTCGCCTAA

Upstream 100 bases:

>100_bases
AACTATAGGGCTAATGCACTGGCCATCCAGGAGTTAACGATGCTGATCATTCGCCTTTATAGCGGTCCGGTTTTTGTCGG
AGATGAAGAGGAACAGGATA

Downstream 100 bases:

>100_bases
TGGAAGGGGGCGCCGCATGCAGCGCCCAATGGGTTAAATCGGGTCGAACATGTTCGACCCCTACGGTTTTACATCAGGGC
TGCGATTACTCCGCCAGCGC

Product: 2OG-Fe(II) oxygenase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTPPLTLKTLPQLSLSQLDGDRRQRQAFLDGLREAARDVGFFYLRGHGVDNRLNAQLQQHARQFFALPEADKLAVQMVHS
PHFRGYNRAAAELTRGQPDWREQFDIGAERPALQLANETPRWARLQGPNQWPEALPALKPLLLQWQQAMTAMSLRLLRAF
ALALSLPEQAFDSLYGDKPNEHIKLIRYPGRDATDSGQGVGAHKDSGFLSFLLQDRQKGLQVEVDEGRWVDAEPLEDSFV
VNIGELLELATNGYLRATVHRVETPPAGSERLSIAFFLGARLDAVVPLYQLPAHLAAEARGPASDPHNPLLRDVGFNYLK
GRIRSHPDVAQRYYQDVVA

Sequences:

>Translated_339_residues
MTPPLTLKTLPQLSLSQLDGDRRQRQAFLDGLREAARDVGFFYLRGHGVDNRLNAQLQQHARQFFALPEADKLAVQMVHS
PHFRGYNRAAAELTRGQPDWREQFDIGAERPALQLANETPRWARLQGPNQWPEALPALKPLLLQWQQAMTAMSLRLLRAF
ALALSLPEQAFDSLYGDKPNEHIKLIRYPGRDATDSGQGVGAHKDSGFLSFLLQDRQKGLQVEVDEGRWVDAEPLEDSFV
VNIGELLELATNGYLRATVHRVETPPAGSERLSIAFFLGARLDAVVPLYQLPAHLAAEARGPASDPHNPLLRDVGFNYLK
GRIRSHPDVAQRYYQDVVA
>Mature_338_residues
TPPLTLKTLPQLSLSQLDGDRRQRQAFLDGLREAARDVGFFYLRGHGVDNRLNAQLQQHARQFFALPEADKLAVQMVHSP
HFRGYNRAAAELTRGQPDWREQFDIGAERPALQLANETPRWARLQGPNQWPEALPALKPLLLQWQQAMTAMSLRLLRAFA
LALSLPEQAFDSLYGDKPNEHIKLIRYPGRDATDSGQGVGAHKDSGFLSFLLQDRQKGLQVEVDEGRWVDAEPLEDSFVV
NIGELLELATNGYLRATVHRVETPPAGSERLSIAFFLGARLDAVVPLYQLPAHLAAEARGPASDPHNPLLRDVGFNYLKG
RIRSHPDVAQRYYQDVVA

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 38031; Mature: 37899

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPLTLKTLPQLSLSQLDGDRRQRQAFLDGLREAARDVGFFYLRGHGVDNRLNAQLQQH
CCCCCCHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHH
ARQFFALPEADKLAVQMVHSPHFRGYNRAAAELTRGQPDWREQFDIGAERPALQLANETP
HHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCHHHHCCCCC
RWARLQGPNQWPEALPALKPLLLQWQQAMTAMSLRLLRAFALALSLPEQAFDSLYGDKPN
CEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
EHIKLIRYPGRDATDSGQGVGAHKDSGFLSFLLQDRQKGLQVEVDEGRWVDAEPLEDSFV
CCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHH
VNIGELLELATNGYLRATVHRVETPPAGSERLSIAFFLGARLDAVVPLYQLPAHLAAEAR
CCHHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCC
GPASDPHNPLLRDVGFNYLKGRIRSHPDVAQRYYQDVVA
CCCCCCCCHHHHHHCHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TPPLTLKTLPQLSLSQLDGDRRQRQAFLDGLREAARDVGFFYLRGHGVDNRLNAQLQQH
CCCCCHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHH
ARQFFALPEADKLAVQMVHSPHFRGYNRAAAELTRGQPDWREQFDIGAERPALQLANETP
HHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCHHHHCCCCC
RWARLQGPNQWPEALPALKPLLLQWQQAMTAMSLRLLRAFALALSLPEQAFDSLYGDKPN
CEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
EHIKLIRYPGRDATDSGQGVGAHKDSGFLSFLLQDRQKGLQVEVDEGRWVDAEPLEDSFV
CCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHH
VNIGELLELATNGYLRATVHRVETPPAGSERLSIAFFLGARLDAVVPLYQLPAHLAAEAR
CCHHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCC
GPASDPHNPLLRDVGFNYLKGRIRSHPDVAQRYYQDVVA
CCCCCCCCHHHHHHCHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3130293 [H]