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The map label for this gene is dcuC [H]

Identifier: 157369822

GI number: 157369822

Start: 1721807

End: 1723165

Strand: Direct

Name: dcuC [H]

Synonym: Spro_1579

Alternate gene names: 157369822

Gene position: 1721807-1723165 (Clockwise)

Preceding gene: 157369821

Following gene: 157369824

Centisome position: 31.6

GC content: 55.63

Gene sequence:

>1359_bases
ATGATAGAGCTTCTGATCGGGGCAGTCGTCGCGGCAGGCGTTGGCCGTTATATCATCAAAGGTTACTCCGCCACTGGCGT
ATTGATGGTAGGTGGCCTGTTACTGTTGGCCATCAGTGCCCTGATGGGCAAAAGTTTGTTGCCTGCCAGCGCCACATCTA
CCGGCTGGCGCGCGACCGACATCATTGAATACGTCAAAATTCTGCTGATGAGCCGTGGTGGCGATCTTGGCATGATGATT
ATGATGCTGTGCGGATTTGCGGCCTATATGACGCACATTGGCGCCAATGATGTGGTGGTCAAGCTGGCATCCCGTCCGCT
ACAAATGATCAATTCCCCCTACCTTTTGATGGTGGCGGCCTATTTTGTTGCCTGTCTGATGTCACTGGCCGTCTCGTCTG
CCACTGGCCTGGGCGTATTGCTGATGGCTACGCTCTTCCCGCTGATGGTCAACGTGGGTATCAGCCGTGGTGCGGCAGCG
GCGATTTGTGCTTCACCCGCGGCGATTATTCTGGCACCAACCTCGGGTGACGTGGTGCTGGCCGCCAAGGCGGCGGAAAT
GCCATTGGTTGATTTCGCCTTTAAAACTACGTTACCCATCTCGATTGCGGCGATTGTCTGCATGGCGGTTGCGCATTTCT
TTTGGCAGCGTTACCTCGACAAGAAGGCCAATGAACAGCATCACATTATGGATGTGAGTGAAATCACCACTCATGCGCCG
GGCTTTTACGCGGTGCTGCCGTTTACCCCTATCCTTGGCGTGCTGGTGTTTGATGGTAAATGGGGGCCGGAACTGCATAT
TATCACCGTGTTGGTTGGCTGTATGCTGCTGGCGGCGGTAATTGAATTCCTGCGCAGCTTCAGCGCCAAACAGGTATTTA
CCGGTCTGGAAGTCGCTTATCGCGGTATGGCGGATGCTTTTGCCAGCGTAGTGATGCTGCTGGTAGCTGCCGGCGTGTTC
GCCCAGGGGCTGAGCACCGTCGGGTTTATCAGCGGGCTGATCAGCCTGGCGCAGTCATTCGGTACCGGCGGCATCATCAT
GATGCTGGTGCTGGTGGTGATTACCATGCTGGCGGCGATGACTACCGGTTCAGGCAACGCTCCGTTCTATGCTTTCGTAG
AGCTGATTCCTAAACTGGCGGCGCAGATGGGGGTTAATCCGGCGTATCTGGTGATCCCGATGCTGCAGGCTTCGAATCTG
GGACGCACTCTGTCGCCGGTTTCCGGGGTGGTGGTGGCGGTATCCGGCATGGCAAAAATCTCGCCGTTCGAAGTGGTGAA
ACGTACTTCGGTACCGGTGATTGTTGGGTTGATCGTGGTGATTGTGGCGACGGAGTTACTGGTTCCCCAGCATTTATAA

Upstream 100 bases:

>100_bases
ATATCATGACGTCTGTGCCTGAGTTTGTGCAGAGTGTGCGCAGTTAAGCGATTTATACGCTTTGGTACGGTCAAAAACGA
AAATGATAAGTTGAGGGAAT

Downstream 100 bases:

>100_bases
TAGCGGCCGAGCGATGCCCGGCCCCGGTTTAAACCTCGTAGTCTGGTTCTGGTACCGACAACGGGGTGATTTTTACCTTC
AAAATACGGTGGCTACTGAC

Product: C4-dicarboxylate transporter DcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MIELLIGAVVAAGVGRYIIKGYSATGVLMVGGLLLLAISALMGKSLLPASATSTGWRATDIIEYVKILLMSRGGDLGMMI
MMLCGFAAYMTHIGANDVVVKLASRPLQMINSPYLLMVAAYFVACLMSLAVSSATGLGVLLMATLFPLMVNVGISRGAAA
AICASPAAIILAPTSGDVVLAAKAAEMPLVDFAFKTTLPISIAAIVCMAVAHFFWQRYLDKKANEQHHIMDVSEITTHAP
GFYAVLPFTPILGVLVFDGKWGPELHIITVLVGCMLLAAVIEFLRSFSAKQVFTGLEVAYRGMADAFASVVMLLVAAGVF
AQGLSTVGFISGLISLAQSFGTGGIIMMLVLVVITMLAAMTTGSGNAPFYAFVELIPKLAAQMGVNPAYLVIPMLQASNL
GRTLSPVSGVVVAVSGMAKISPFEVVKRTSVPVIVGLIVVIVATELLVPQHL

Sequences:

>Translated_452_residues
MIELLIGAVVAAGVGRYIIKGYSATGVLMVGGLLLLAISALMGKSLLPASATSTGWRATDIIEYVKILLMSRGGDLGMMI
MMLCGFAAYMTHIGANDVVVKLASRPLQMINSPYLLMVAAYFVACLMSLAVSSATGLGVLLMATLFPLMVNVGISRGAAA
AICASPAAIILAPTSGDVVLAAKAAEMPLVDFAFKTTLPISIAAIVCMAVAHFFWQRYLDKKANEQHHIMDVSEITTHAP
GFYAVLPFTPILGVLVFDGKWGPELHIITVLVGCMLLAAVIEFLRSFSAKQVFTGLEVAYRGMADAFASVVMLLVAAGVF
AQGLSTVGFISGLISLAQSFGTGGIIMMLVLVVITMLAAMTTGSGNAPFYAFVELIPKLAAQMGVNPAYLVIPMLQASNL
GRTLSPVSGVVVAVSGMAKISPFEVVKRTSVPVIVGLIVVIVATELLVPQHL
>Mature_452_residues
MIELLIGAVVAAGVGRYIIKGYSATGVLMVGGLLLLAISALMGKSLLPASATSTGWRATDIIEYVKILLMSRGGDLGMMI
MMLCGFAAYMTHIGANDVVVKLASRPLQMINSPYLLMVAAYFVACLMSLAVSSATGLGVLLMATLFPLMVNVGISRGAAA
AICASPAAIILAPTSGDVVLAAKAAEMPLVDFAFKTTLPISIAAIVCMAVAHFFWQRYLDKKANEQHHIMDVSEITTHAP
GFYAVLPFTPILGVLVFDGKWGPELHIITVLVGCMLLAAVIEFLRSFSAKQVFTGLEVAYRGMADAFASVVMLLVAAGVF
AQGLSTVGFISGLISLAQSFGTGGIIMMLVLVVITMLAAMTTGSGNAPFYAFVELIPKLAAQMGVNPAYLVIPMLQASNL
GRTLSPVSGVVVAVSGMAKISPFEVVKRTSVPVIVGLIVVIVATELLVPQHL

Specific function: Responsible for the transport of C4-dicarboxylates during anaerobic growth [H]

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1786839, Length=434, Percent_Identity=83.4101382488479, Blast_Score=635, Evalue=0.0,
Organism=Escherichia coli, GI1789622, Length=450, Percent_Identity=36, Blast_Score=281, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 47232; Mature: 47232

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELLIGAVVAAGVGRYIIKGYSATGVLMVGGLLLLAISALMGKSLLPASATSTGWRATD
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
IIEYVKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDVVVKLASRPLQMINSPYLLMVAA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHH
YFVACLMSLAVSSATGLGVLLMATLFPLMVNVGISRGAAAAICASPAAIILAPTSGDVVL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCCEEE
AAKAAEMPLVDFAFKTTLPISIAAIVCMAVAHFFWQRYLDKKANEQHHIMDVSEITTHAP
EECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCEEHHHHHCCCC
GFYAVLPFTPILGVLVFDGKWGPELHIITVLVGCMLLAAVIEFLRSFSAKQVFTGLEVAY
CCEEHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RGMADAFASVVMLLVAAGVFAQGLSTVGFISGLISLAQSFGTGGIIMMLVLVVITMLAAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TTGSGNAPFYAFVELIPKLAAQMGVNPAYLVIPMLQASNLGRTLSPVSGVVVAVSGMAKI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHCCCCCCC
SPFEVVKRTSVPVIVGLIVVIVATELLVPQHL
CHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIELLIGAVVAAGVGRYIIKGYSATGVLMVGGLLLLAISALMGKSLLPASATSTGWRATD
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
IIEYVKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDVVVKLASRPLQMINSPYLLMVAA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHH
YFVACLMSLAVSSATGLGVLLMATLFPLMVNVGISRGAAAAICASPAAIILAPTSGDVVL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCCEEE
AAKAAEMPLVDFAFKTTLPISIAAIVCMAVAHFFWQRYLDKKANEQHHIMDVSEITTHAP
EECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCEEHHHHHCCCC
GFYAVLPFTPILGVLVFDGKWGPELHIITVLVGCMLLAAVIEFLRSFSAKQVFTGLEVAY
CCEEHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RGMADAFASVVMLLVAAGVFAQGLSTVGFISGLISLAQSFGTGGIIMMLVLVVITMLAAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TTGSGNAPFYAFVELIPKLAAQMGVNPAYLVIPMLQASNLGRTLSPVSGVVVAVSGMAKI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHCCCCCCC
SPFEVVKRTSVPVIVGLIVVIVATELLVPQHL
CHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]