Click here to switch to the map view.

The map label for this gene is udk

Identifier: 157369819

GI number: 157369819

Start: 1718381

End: 1719022

Strand: Direct

Name: udk

Synonym: Spro_1576

Alternate gene names: 157369819

Gene position: 1718381-1719022 (Clockwise)

Preceding gene: 157369817

Following gene: 157369820

Centisome position: 31.54

GC content: 47.98

Gene sequence:

>642_bases
ATGACTGACAAGCCGCATCAGTGCGTCATTATTGGTATAGCTGGCGCATCTGCCTCCGGAAAAAGCCTTATCGCCAGTAC
GTTGTATCGTGAACTTCGCGATCAGGTTGGCGATGAACATATCGGCGTTATTCCTGAAGACAGTTACTACAAAGACCAGA
CTCACTTGACCATGGAAGAAAGGGTCAAGACAAACTATGACCACCCAAGCGCCATGGACCACAACCTGCTGTTTCAGCAT
CTGCAGATGCTGAAATCAGGCAAGGCGATAGAGTTACCCTTGTACAGTTACACCGAGCACACGCGTAAGAAAGAGACTAT
TCACCTTGAACCGAAAAAGGTGATTATTCTTGAGGGGATCCTGCTGTTGACGGATATCCGTCTGCGTCAGGAAATGAATT
TCTCGATCTTTGTTGATACGCCGCTGGATATTTGCCTGATGCGCCGTATGAAGCGTGATGTGAATGAACGTGGTCGCTCG
ATGGATTCGGTAATGGCGCAATATCAGAAAACCGTCCGCCCGATGTTCCTGCAGTTTATCGATCCTTCCAAACAATACGC
CGACATTATCGTCCCACGCGGGGGTAAAAACCGCATTGCGATCGATATTCTGAAAGCCAAAATCAGCCAGTTCTTTGAGT
AA

Upstream 100 bases:

>100_bases
TGGCGGTGACAATATAGTCTGGCGCTAAGGGCACTAACTCCCTATAATTGACGCGTTTTAGTTCCCCCCCTTCACACTAC
GAAATCAGGTCTTCAATTTT

Downstream 100 bases:

>100_bases
TGCCGTTCAATGGCCGGAAAACCCGTGTTTCCGGCCGGCGGGCAACTATTTACGCCGCGGCGTAGACCTTTCGCCCGTTG
TGTGGCAATTTTTGTTTTAG

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTDKPHQCVIIGIAGASASGKSLIASTLYRELRDQVGDEHIGVIPEDSYYKDQTHLTMEERVKTNYDHPSAMDHNLLFQH
LQMLKSGKAIELPLYSYTEHTRKKETIHLEPKKVIILEGILLLTDIRLRQEMNFSIFVDTPLDICLMRRMKRDVNERGRS
MDSVMAQYQKTVRPMFLQFIDPSKQYADIIVPRGGKNRIAIDILKAKISQFFE

Sequences:

>Translated_213_residues
MTDKPHQCVIIGIAGASASGKSLIASTLYRELRDQVGDEHIGVIPEDSYYKDQTHLTMEERVKTNYDHPSAMDHNLLFQH
LQMLKSGKAIELPLYSYTEHTRKKETIHLEPKKVIILEGILLLTDIRLRQEMNFSIFVDTPLDICLMRRMKRDVNERGRS
MDSVMAQYQKTVRPMFLQFIDPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
>Mature_212_residues
TDKPHQCVIIGIAGASASGKSLIASTLYRELRDQVGDEHIGVIPEDSYYKDQTHLTMEERVKTNYDHPSAMDHNLLFQHL
QMLKSGKAIELPLYSYTEHTRKKETIHLEPKKVIILEGILLLTDIRLRQEMNFSIFVDTPLDICLMRRMKRDVNERGRSM
DSVMAQYQKTVRPMFLQFIDPSKQYADIIVPRGGKNRIAIDILKAKISQFFE

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family

Homologues:

Organism=Homo sapiens, GI57863312, Length=200, Percent_Identity=40.5, Blast_Score=158, Evalue=3e-39,
Organism=Homo sapiens, GI301129207, Length=200, Percent_Identity=40.5, Blast_Score=158, Evalue=3e-39,
Organism=Homo sapiens, GI18699734, Length=203, Percent_Identity=35.9605911330049, Blast_Score=154, Evalue=4e-38,
Organism=Homo sapiens, GI13899253, Length=213, Percent_Identity=37.0892018779343, Blast_Score=144, Evalue=7e-35,
Organism=Homo sapiens, GI209863022, Length=160, Percent_Identity=35, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI87082034, Length=213, Percent_Identity=88.7323943661972, Blast_Score=398, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17539894, Length=207, Percent_Identity=37.6811594202899, Blast_Score=150, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17539892, Length=207, Percent_Identity=37.6811594202899, Blast_Score=150, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI71981181, Length=216, Percent_Identity=32.8703703703704, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324339, Length=177, Percent_Identity=32.7683615819209, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI221458995, Length=219, Percent_Identity=35.6164383561644, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24649624, Length=210, Percent_Identity=36.1904761904762, Blast_Score=147, Evalue=4e-36,
Organism=Drosophila melanogaster, GI28573516, Length=197, Percent_Identity=37.5634517766497, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28573514, Length=197, Percent_Identity=37.5634517766497, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28573512, Length=197, Percent_Identity=37.5634517766497, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI45550449, Length=197, Percent_Identity=37.5634517766497, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URK_SERP5 (A8GC40)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477808.1
- ProteinModelPortal:   A8GC40
- STRING:   A8GC40
- GeneID:   5602922
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_1576
- eggNOG:   COG0572
- HOGENOM:   HBG527126
- OMA:   DQIGVIA
- ProtClustDB:   PRK05480
- BioCyc:   SPRO399741:SPRO_1576-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00551
- InterPro:   IPR006083
- InterPro:   IPR000764
- PANTHER:   PTHR10285:SF6
- PRINTS:   PR00988
- TIGRFAMs:   TIGR00235

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.48

Molecular weight: Translated: 24622; Mature: 24491

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKPHQCVIIGIAGASASGKSLIASTLYRELRDQVGDEHIGVIPEDSYYKDQTHLTMEE
CCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHH
RVKTNYDHPSAMDHNLLFQHLQMLKSGKAIELPLYSYTEHTRKKETIHLEPKKVIILEGI
HHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCEEEECCCEEEEEHHH
LLLTDIRLRQEMNFSIFVDTPLDICLMRRMKRDVNERGRSMDSVMAQYQKTVRPMFLQFI
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
DPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
CCCCHHHEEEEECCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDKPHQCVIIGIAGASASGKSLIASTLYRELRDQVGDEHIGVIPEDSYYKDQTHLTMEE
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHH
RVKTNYDHPSAMDHNLLFQHLQMLKSGKAIELPLYSYTEHTRKKETIHLEPKKVIILEGI
HHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCEEEECCCEEEEEHHH
LLLTDIRLRQEMNFSIFVDTPLDICLMRRMKRDVNERGRSMDSVMAQYQKTVRPMFLQFI
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
DPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
CCCCHHHEEEEECCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA