Click here to switch to the map view.

The map label for this gene is dinG [H]

Identifier: 157369704

GI number: 157369704

Start: 1592292

End: 1594490

Strand: Direct

Name: dinG [H]

Synonym: Spro_1461

Alternate gene names: 157369704

Gene position: 1592292-1594490 (Clockwise)

Preceding gene: 157369703

Following gene: 157369706

Centisome position: 29.22

GC content: 56.93

Gene sequence:

>2199_bases
ATGGCGCTCTCCCCCGCAGTTAAAGATCAGATTGGCCAGTGGTACAAAGCCCTGCAGCAGCAAATACCGGATTTTATTTC
CCGTGCACCGCAACGGCAGATGATCGCCGAAGTGGCAAAAACGCTGGCCGGTGATTACCCGCGCCATCTGGCGATTGAGG
CTCCGACCGGCGTAGGTAAAACCTTGTCATACCTGATCCCGGGGATCGCCGTCGGCCGCGCAGAGAGTAAACCTCTGGTG
GTCAGCACCGCCAACGTGGCATTGCAGGATCAGATCTATAGCAAGGATTTGCCGCTGCTGAAGAAGATCATTCCCGATCT
GAAATTTACCGGTGCCTTTGGCCGCGGGCGCTATGTTTGCCCGCGTAACCTGGCGGCGCTCTGCACTGATGTCAGCGAGC
AGGGCGACCTGATGCTGTTTCTGGGTGACGAACTTGCGCCTTCGAGCGGTGAAGAACAGGCGCTGTGCCAGAAGCTAAGC
AAGGCGCTCAGCCGCCATGAGTGGGACGGGCTGCGCGACCATTATCAACTGTCGATTGACGATCCGCTGTGGATCAAACT
GAGCACCGATAAAGCCAACTGCCTGGGCCGTAACTGCCATTACATTCGTGAATGCCCGTTTTATATCGCGCGTAAAGAGA
TTGAAACCGCCGACGTGGTGGTGGCTAACCATGCGTTGGTGATGGCGGCGCTGGAAACCGAGTCGGTACTGCCGAACCCG
AAAGAGCTGCTGCTGGTGCTGGACGAAGGGCATCATCTGCCGGAGGTAGCGCGTGACGCGCTGGAGATTGAAGGTGAAAT
CACCGCCTTATCGACCAATCTGCAGTTGGACATGATCGTGCGCCAGGTTGAGCTGTGCATGACGCAATACCGGCCGAAAA
GTCCGCCGGGGTTGGCAAACGACGAACGTTTGAAGAACCACTGTGAAGAACTGCGCGAACTGATCCAAATCTTCGAGCAT
CAGGTCAGCGCCTATCTGCCGACCGATACGGTCATCGCCGAACATCGATTTGAAATGGGGGAACTGCCGACGGATATGGT
AGAAACCTGCGCACGATTATTCAAGCTTACCGACGCCTTGCGCGGGCTGGCGGAGTTTATCGTCAACGATCTCAGCGAAC
AGACCGGCAAGCACGACATTGTGCGGCTGCATCGTTCGATCATTCAGATGAGCCGCACCCTGGGCTATCTGGAGGCGATG
AGTAAACTGTGGCGGCTGGCCGCGCTGGATAAATCTTCCAACGCACCGATCTCCAAATGGGTCACGCGCGATCTGCGTGA
TAACGTGACCCACCTGTACCTGCATTGTGTGGGCATTCGCGTCAGCGATCAGTTGGAAAAGCTGCTATGGCGTAAGGTGC
CGCACGTGGTGATCACCTCGGCGACGCTGCGCTCGCTGAACAGCTTTGCGCGGCTGCAGGAAATGAGCGGCCTGAGTGAA
AAGGCCGGCGATCGCTTTGAATCCCTGTCTTCCCCCTTCAATCATGTGGAACAGGGCAAAATTGTTATTCCGAATATGCG
CTTTGAGCCGTCGATGGCCAATGAAGCCGAACATCTGGAAGAGATGGCGCGCTTTTTCCGCGCCGAGCAGGCCACTGGCA
AGCACAAAGGGATGCTGATCCTGTTCAGCAGCCACCGGGCGATGCAGACCTTCCTCAGCTATGTGACCGATCTGCGCCTG
ATGCTGCTGGTACAGGGCGATCAGCCACGCTATCGGCTGGTGGAAGAACACCGTAAACGGGTCGAAAAGGGCACGGCCAG
CGTGTTAATCGGCCTGCAGTCGTTTGCCGAAGGGCTGGATCTAAAAGGTGAGCTGCTGACCCAGGTGCATATCCACAAAA
TCGCTTTCCCGCCCATCGACAGCCCGGTGATCCTGACCGAGGGGGAATGGCTAAAATCGCTGAAGCGTTATCCGTTTGAA
GTGCAGAGCCTGCCAAGCGCCTCGTTCAACCTGATCCAACAGGTGGGGCGACTGATCCGCAGTAATGAATGCCACGGCGA
GATCGTGATTTACGATCGCCGCCTGCTGACCAAAAGCTACGGTTCGCGTTTGCTGGCGTCACTGCCGGTATTTCCTATCG
AACAGCGGGAAGTGCCAGAGGCCGACAAGGCACACCTGGCCGCCATTAAATCTGCCGCTGCGGCGGAGAAAAAAGACAAA
AAGCGCAAGAGTCCGTTCGCCCGCCGACGTACGCGTTAA

Upstream 100 bases:

>100_bases
CGTTCAGTGCGGGACGCGCCTCAATGATTGAAGGCCAGGCTGACGTAGCCGACGGTCTGTGGGACAATAGCGCCATCATT
TCGTAGAGATATAGAGTTGA

Downstream 100 bases:

>100_bases
TCAAAGCAGCGGGGGCAGGCGGCGCTTCACCGGCGTGGTTTTGACGATGGAAGTGTTGCTCTGCGCGCGCTCGGCCAGCC
GATCGAGGATCTGGTCGAGT

Product: ATP-dependent DNA helicase DinG

Products: NA

Alternate protein names: DNA-damage-inducible protein G [H]

Number of amino acids: Translated: 732; Mature: 731

Protein sequence:

>732_residues
MALSPAVKDQIGQWYKALQQQIPDFISRAPQRQMIAEVAKTLAGDYPRHLAIEAPTGVGKTLSYLIPGIAVGRAESKPLV
VSTANVALQDQIYSKDLPLLKKIIPDLKFTGAFGRGRYVCPRNLAALCTDVSEQGDLMLFLGDELAPSSGEEQALCQKLS
KALSRHEWDGLRDHYQLSIDDPLWIKLSTDKANCLGRNCHYIRECPFYIARKEIETADVVVANHALVMAALETESVLPNP
KELLLVLDEGHHLPEVARDALEIEGEITALSTNLQLDMIVRQVELCMTQYRPKSPPGLANDERLKNHCEELRELIQIFEH
QVSAYLPTDTVIAEHRFEMGELPTDMVETCARLFKLTDALRGLAEFIVNDLSEQTGKHDIVRLHRSIIQMSRTLGYLEAM
SKLWRLAALDKSSNAPISKWVTRDLRDNVTHLYLHCVGIRVSDQLEKLLWRKVPHVVITSATLRSLNSFARLQEMSGLSE
KAGDRFESLSSPFNHVEQGKIVIPNMRFEPSMANEAEHLEEMARFFRAEQATGKHKGMLILFSSHRAMQTFLSYVTDLRL
MLLVQGDQPRYRLVEEHRKRVEKGTASVLIGLQSFAEGLDLKGELLTQVHIHKIAFPPIDSPVILTEGEWLKSLKRYPFE
VQSLPSASFNLIQQVGRLIRSNECHGEIVIYDRRLLTKSYGSRLLASLPVFPIEQREVPEADKAHLAAIKSAAAAEKKDK
KRKSPFARRRTR

Sequences:

>Translated_732_residues
MALSPAVKDQIGQWYKALQQQIPDFISRAPQRQMIAEVAKTLAGDYPRHLAIEAPTGVGKTLSYLIPGIAVGRAESKPLV
VSTANVALQDQIYSKDLPLLKKIIPDLKFTGAFGRGRYVCPRNLAALCTDVSEQGDLMLFLGDELAPSSGEEQALCQKLS
KALSRHEWDGLRDHYQLSIDDPLWIKLSTDKANCLGRNCHYIRECPFYIARKEIETADVVVANHALVMAALETESVLPNP
KELLLVLDEGHHLPEVARDALEIEGEITALSTNLQLDMIVRQVELCMTQYRPKSPPGLANDERLKNHCEELRELIQIFEH
QVSAYLPTDTVIAEHRFEMGELPTDMVETCARLFKLTDALRGLAEFIVNDLSEQTGKHDIVRLHRSIIQMSRTLGYLEAM
SKLWRLAALDKSSNAPISKWVTRDLRDNVTHLYLHCVGIRVSDQLEKLLWRKVPHVVITSATLRSLNSFARLQEMSGLSE
KAGDRFESLSSPFNHVEQGKIVIPNMRFEPSMANEAEHLEEMARFFRAEQATGKHKGMLILFSSHRAMQTFLSYVTDLRL
MLLVQGDQPRYRLVEEHRKRVEKGTASVLIGLQSFAEGLDLKGELLTQVHIHKIAFPPIDSPVILTEGEWLKSLKRYPFE
VQSLPSASFNLIQQVGRLIRSNECHGEIVIYDRRLLTKSYGSRLLASLPVFPIEQREVPEADKAHLAAIKSAAAAEKKDK
KRKSPFARRRTR
>Mature_731_residues
ALSPAVKDQIGQWYKALQQQIPDFISRAPQRQMIAEVAKTLAGDYPRHLAIEAPTGVGKTLSYLIPGIAVGRAESKPLVV
STANVALQDQIYSKDLPLLKKIIPDLKFTGAFGRGRYVCPRNLAALCTDVSEQGDLMLFLGDELAPSSGEEQALCQKLSK
ALSRHEWDGLRDHYQLSIDDPLWIKLSTDKANCLGRNCHYIRECPFYIARKEIETADVVVANHALVMAALETESVLPNPK
ELLLVLDEGHHLPEVARDALEIEGEITALSTNLQLDMIVRQVELCMTQYRPKSPPGLANDERLKNHCEELRELIQIFEHQ
VSAYLPTDTVIAEHRFEMGELPTDMVETCARLFKLTDALRGLAEFIVNDLSEQTGKHDIVRLHRSIIQMSRTLGYLEAMS
KLWRLAALDKSSNAPISKWVTRDLRDNVTHLYLHCVGIRVSDQLEKLLWRKVPHVVITSATLRSLNSFARLQEMSGLSEK
AGDRFESLSSPFNHVEQGKIVIPNMRFEPSMANEAEHLEEMARFFRAEQATGKHKGMLILFSSHRAMQTFLSYVTDLRLM
LLVQGDQPRYRLVEEHRKRVEKGTASVLIGLQSFAEGLDLKGELLTQVHIHKIAFPPIDSPVILTEGEWLKSLKRYPFEV
QSLPSASFNLIQQVGRLIRSNECHGEIVIYDRRLLTKSYGSRLLASLPVFPIEQREVPEADKAHLAAIKSAAAAEKKDKK
RKSPFARRRTR

Specific function: Probable helicase involved in DNA repair and perhaps also replication [H]

COG id: COG1199

COG function: function code KL; Rad3-related DNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787018, Length=730, Percent_Identity=70.2739726027397, Blast_Score=1051, Evalue=0.0,
Organism=Escherichia coli, GI1788110, Length=704, Percent_Identity=29.5454545454545, Blast_Score=191, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR010614
- InterPro:   IPR011545
- InterPro:   IPR014013
- InterPro:   IPR006555
- InterPro:   IPR001650 [H]

Pfam domain/function: PF00270 DEAD; PF06733 DEAD_2 [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 82625; Mature: 82493

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSPAVKDQIGQWYKALQQQIPDFISRAPQRQMIAEVAKTLAGDYPRHLAIEAPTGVGK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHH
TLSYLIPGIAVGRAESKPLVVSTANVALQDQIYSKDLPLLKKIIPDLKFTGAFGRGRYVC
HHHHHHCCCEECCCCCCCEEEEECCHHHHHHHHHCCCHHHHHHCCCCEECCCCCCCCCCC
PRNLAALCTDVSEQGDLMLFLGDELAPSSGEEQALCQKLSKALSRHEWDGLRDHYQLSID
CCHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
DPLWIKLSTDKANCLGRNCHYIRECPFYIARKEIETADVVVANHALVMAALETESVLPNP
CCEEEEEECCCHHHCCCCCHHHHHCCHHHHHHHCCHHHEEEECCCEEEEEHHHHHCCCCH
KELLLVLDEGHHLPEVARDALEIEGEITALSTNLQLDMIVRQVELCMTQYRPKSPPGLAN
HHEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCC
DERLKNHCEELRELIQIFEHQVSAYLPTDTVIAEHRFEMGELPTDMVETCARLFKLTDAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
RGLAEFIVNDLSEQTGKHDIVRLHRSIIQMSRTLGYLEAMSKLWRLAALDKSSNAPISKW
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VTRDLRDNVTHLYLHCVGIRVSDQLEKLLWRKVPHVVITSATLRSLNSFARLQEMSGLSE
HHHHHHHHHHEEHHHHCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCHH
KAGDRFESLSSPFNHVEQGKIVIPNMRFEPSMANEAEHLEEMARFFRAEQATGKHKGMLI
HHHHHHHHHCCCHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEE
LFSSHRAMQTFLSYVTDLRLMLLVQGDQPRYRLVEEHRKRVEKGTASVLIGLQSFAEGLD
EECCCHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCC
LKGELLTQVHIHKIAFPPIDSPVILTEGEWLKSLKRYPFEVQSLPSASFNLIQQVGRLIR
CCHHHHHHHHHHHEECCCCCCCEEEECCHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHH
SNECHGEIVIYDRRLLTKSYGSRLLASLPVFPIEQREVPEADKAHLAAIKSAAAAEKKDK
CCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KRKSPFARRRTR
HHCCCHHHCCCC
>Mature Secondary Structure 
ALSPAVKDQIGQWYKALQQQIPDFISRAPQRQMIAEVAKTLAGDYPRHLAIEAPTGVGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHH
TLSYLIPGIAVGRAESKPLVVSTANVALQDQIYSKDLPLLKKIIPDLKFTGAFGRGRYVC
HHHHHHCCCEECCCCCCCEEEEECCHHHHHHHHHCCCHHHHHHCCCCEECCCCCCCCCCC
PRNLAALCTDVSEQGDLMLFLGDELAPSSGEEQALCQKLSKALSRHEWDGLRDHYQLSID
CCHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
DPLWIKLSTDKANCLGRNCHYIRECPFYIARKEIETADVVVANHALVMAALETESVLPNP
CCEEEEEECCCHHHCCCCCHHHHHCCHHHHHHHCCHHHEEEECCCEEEEEHHHHHCCCCH
KELLLVLDEGHHLPEVARDALEIEGEITALSTNLQLDMIVRQVELCMTQYRPKSPPGLAN
HHEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCC
DERLKNHCEELRELIQIFEHQVSAYLPTDTVIAEHRFEMGELPTDMVETCARLFKLTDAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
RGLAEFIVNDLSEQTGKHDIVRLHRSIIQMSRTLGYLEAMSKLWRLAALDKSSNAPISKW
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VTRDLRDNVTHLYLHCVGIRVSDQLEKLLWRKVPHVVITSATLRSLNSFARLQEMSGLSE
HHHHHHHHHHEEHHHHCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCHH
KAGDRFESLSSPFNHVEQGKIVIPNMRFEPSMANEAEHLEEMARFFRAEQATGKHKGMLI
HHHHHHHHHCCCHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEE
LFSSHRAMQTFLSYVTDLRLMLLVQGDQPRYRLVEEHRKRVEKGTASVLIGLQSFAEGLD
EECCCHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCC
LKGELLTQVHIHKIAFPPIDSPVILTEGEWLKSLKRYPFEVQSLPSASFNLIQQVGRLIR
CCHHHHHHHHHHHEECCCCCCCEEEECCHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHH
SNECHGEIVIYDRRLLTKSYGSRLLASLPVFPIEQREVPEADKAHLAAIKSAAAAEKKDK
CCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KRKSPFARRRTR
HHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]