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The map label for this gene is yehW [H]

Identifier: 157369691

GI number: 157369691

Start: 1581649

End: 1582431

Strand: Direct

Name: yehW [H]

Synonym: Spro_1448

Alternate gene names: 157369691

Gene position: 1581649-1582431 (Clockwise)

Preceding gene: 157369690

Following gene: 157369692

Centisome position: 29.03

GC content: 60.79

Gene sequence:

>783_bases
ATGAGTGCGCTTCGGGCCCTGCGCTGGCTGCGCGATCCGCTGCCCTGGACCTTTGCCCTGTTGTTGGCACTGGTGTTCGG
CATGAATCATTTACACGGCCTGTTTGCCGCCTGGTTTCCCGAACTGGAGCGGCCGGTGTATCAGCAGGACAGCTTTATCT
CACTGGTGTGGGCGCATCTGTTGCTGGTGGCGGTTTCCAGCCTGGTTGCCGTGGTGATTGGCGTCAGCGCCGGCGTCGCT
GTAACGCGCCGCGCCGGTAAGGAGTTCCGCTCATTGGTGGAAACCCTGGTGGCGGTGGGGCAGACATTTCCGCCGGTGGC
GGTACTGGCGATCGCAGTGCCGGTGATGGGCTTTAGTGAGCAGCCGGCGATCATCGCGCTGGTGCTGTACGGTTTACTGC
CGATCTTGCAGGGCACGCTGGCGGGGATTGAGTCTGTGCCCAGCGCTACCCGCGAGATTGCGCAGGGAGTAGGGATGAGC
CCCCGACAGATCCTGTGGCGCGTCGAACTGCCGCTGGCGGCGCCGGTGATCGTCGCCGGCATTCGTACCTCGGTGATCAT
TAATATTGGTACAGCGGCGATAGCTTCTACCGTTGGTACCAAAACCCTGGGATCGCCGATTATTATTGGCCTGAGCGGCT
TTAATACTGCCTATGTGATCCAGGGCGCGGTGGTGGTGGCCCTGTTGGCGATCATTACCGATATGCTGTTTGAGCGTTGG
GTACGCCATCTCACCGCCTGGCGTCAGCAAGCGCTGGTGACTTCTTCTTCTTCTGCCGGATAA

Upstream 100 bases:

>100_bases
TTGTGGCACGCGGCTGCGAATGTTTGCCGGTGACGGGTGAACAGGGCGAAGCGCTCGGGGTGCTGCATTTCAGCGATCTG
ATTGTCCAAAAGGCGCTGTC

Downstream 100 bases:

>100_bases
GGGAACATGATGCAGGTATCTTTACCGATGTACGGCGTGACACATCAACCGGCGGAAGCCTTCTGGCGGGTGCTGCGCGG
CAAGTTACTGCAACTGGGAT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MSALRALRWLRDPLPWTFALLLALVFGMNHLHGLFAAWFPELERPVYQQDSFISLVWAHLLLVAVSSLVAVVIGVSAGVA
VTRRAGKEFRSLVETLVAVGQTFPPVAVLAIAVPVMGFSEQPAIIALVLYGLLPILQGTLAGIESVPSATREIAQGVGMS
PRQILWRVELPLAAPVIVAGIRTSVIINIGTAAIASTVGTKTLGSPIIIGLSGFNTAYVIQGAVVVALLAIITDMLFERW
VRHLTAWRQQALVTSSSSAG

Sequences:

>Translated_260_residues
MSALRALRWLRDPLPWTFALLLALVFGMNHLHGLFAAWFPELERPVYQQDSFISLVWAHLLLVAVSSLVAVVIGVSAGVA
VTRRAGKEFRSLVETLVAVGQTFPPVAVLAIAVPVMGFSEQPAIIALVLYGLLPILQGTLAGIESVPSATREIAQGVGMS
PRQILWRVELPLAAPVIVAGIRTSVIINIGTAAIASTVGTKTLGSPIIIGLSGFNTAYVIQGAVVVALLAIITDMLFERW
VRHLTAWRQQALVTSSSSAG
>Mature_259_residues
SALRALRWLRDPLPWTFALLLALVFGMNHLHGLFAAWFPELERPVYQQDSFISLVWAHLLLVAVSSLVAVVIGVSAGVAV
TRRAGKEFRSLVETLVAVGQTFPPVAVLAIAVPVMGFSEQPAIIALVLYGLLPILQGTLAGIESVPSATREIAQGVGMSP
RQILWRVELPLAAPVIVAGIRTSVIINIGTAAIASTVGTKTLGSPIIIGLSGFNTAYVIQGAVVVALLAIITDMLFERWV
RHLTAWRQQALVTSSSSAG

Specific function: May be part of an ABC transporter complex involved in uptake of osmoprotectant molecules. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=239, Percent_Identity=66.9456066945607, Blast_Score=302, Evalue=1e-83,
Organism=Escherichia coli, GI1788451, Length=217, Percent_Identity=33.6405529953917, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789033, Length=171, Percent_Identity=32.1637426900585, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 27659; Mature: 27528

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALRALRWLRDPLPWTFALLLALVFGMNHLHGLFAAWFPELERPVYQQDSFISLVWAHL
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHH
LLVAVSSLVAVVIGVSAGVAVTRRAGKEFRSLVETLVAVGQTFPPVAVLAIAVPVMGFSE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
QPAIIALVLYGLLPILQGTLAGIESVPSATREIAQGVGMSPRQILWRVELPLAAPVIVAG
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHEEECCCHHHHHHHHH
IRTSVIINIGTAAIASTVGTKTLGSPIIIGLSGFNTAYVIQGAVVVALLAIITDMLFERW
HHHHHEEECHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VRHLTAWRQQALVTSSSSAG
HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SALRALRWLRDPLPWTFALLLALVFGMNHLHGLFAAWFPELERPVYQQDSFISLVWAHL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHH
LLVAVSSLVAVVIGVSAGVAVTRRAGKEFRSLVETLVAVGQTFPPVAVLAIAVPVMGFSE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
QPAIIALVLYGLLPILQGTLAGIESVPSATREIAQGVGMSPRQILWRVELPLAAPVIVAG
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHEEECCCHHHHHHHHH
IRTSVIINIGTAAIASTVGTKTLGSPIIIGLSGFNTAYVIQGAVVVALLAIITDMLFERW
HHHHHEEECHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VRHLTAWRQQALVTSSSSAG
HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]