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The map label for this gene is fecD [C]

Identifier: 157369616

GI number: 157369616

Start: 1503860

End: 1504858

Strand: Direct

Name: fecD [C]

Synonym: Spro_1373

Alternate gene names: 157369616

Gene position: 1503860-1504858 (Clockwise)

Preceding gene: 157369615

Following gene: 157369617

Centisome position: 27.6

GC content: 60.86

Gene sequence:

>999_bases
ATGAAGCTGGGCTGGCTTATCCTGCTGACGTTGCTCTGCGCATTGCTGTCATTGGGCATTGGTCGCTACCCGGTCTCGGC
GACTCACAGCGTGATGATCCTGCTGGAGCCGCTGACCGGCCCGCACGGTGGCATTGATGAGGTACAACGTCAGGTGATCC
TTGGGGTGCGCGTGCCCAGGGTGTTGCTGGCGATGGGCGCCGGGGCGGCATTGGCCCTGTGCGGCGCGGCGCTGCAGGGC
GTGTTTCGCAACCCATTGGTGGATCCGCATATTATCGGCGTCTCCTCCGGTGCGGCATTTGGCGGCACGCTGGCGATATT
ACTCAGCCTGCCGATGGCGGCGCTGTTGCTGTCTGCTTTCGTGTTCGGCATGGCGGCCCTGCTGCTGATTTTTGCCATTA
CCAGCGCTATCGCCCGGCGCAATATTCTGTCGCTGGTGCTGGCCGGCGTGATCCTCAGTGGCTTTTTCTCCGCCTGCGTC
AGCCTGCTACAATATCTCGCCGATACCGAAGAGAAACTGCCGAGCATCGTGTTCTGGTTGCTGGGCAGCTTCGCGACCGC
CGACGATAACAAACTTTTGATGCTGTTCCTGCCGTTGCTGCTGGCCGGTGGGCTGCTGTTGGCATTGCGCTGGCGTATTA
ATTTGTTGTCGCTGGGGGATGAGGATGCTGCAGGATTGGGCATCAATGTCGAACGAACCCGCTGGCTGATTTTGACGCTG
TGTGCCGCCATCGTCGCGGCGCAGGTGGCGGTCAGTGGCAGCATTGGCTGGGTTGGGTTGGTGATACCGCATGTTGCCCG
GTTGCTGGTCGGCCCGGATCATCGTCGCCTGCTGCCTGCCTCTATGTGCCTTGGGGCGCTGTATATGGTGTTGATAGACG
ATTTGGCGCGTACCCTGAGCAGCAGCGAAATCCCATTGGGGATCCTGACTGCGCTGATTGGTGCGCCGCTGTTTGCGTTG
CTGTTGCGCCGGGCGCAACTGAGAGGTTGGCATGGCTGA

Upstream 100 bases:

>100_bases
AAAAGCTTTATCCGCAGCGGTTTAGCGACGTTAATTTACAACAGCGGGTGGACGCCTACTACCGGCAGTATTACCGCAGT
AGCTGCTGCCAGAGTGAGCA

Downstream 100 bases:

>100_bases
GACGCTATTGACGGTCAGGGATTTGAGCTTTGGCTGGCCCGGTCAGGCCCCGTTGTTTAACCGGTTGGATCTGCAGTTAC
AGCGCGGTGAGGTGCTGGCG

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKLGWLILLTLLCALLSLGIGRYPVSATHSVMILLEPLTGPHGGIDEVQRQVILGVRVPRVLLAMGAGAALALCGAALQG
VFRNPLVDPHIIGVSSGAAFGGTLAILLSLPMAALLLSAFVFGMAALLLIFAITSAIARRNILSLVLAGVILSGFFSACV
SLLQYLADTEEKLPSIVFWLLGSFATADDNKLLMLFLPLLLAGGLLLALRWRINLLSLGDEDAAGLGINVERTRWLILTL
CAAIVAAQVAVSGSIGWVGLVIPHVARLLVGPDHRRLLPASMCLGALYMVLIDDLARTLSSSEIPLGILTALIGAPLFAL
LLRRAQLRGWHG

Sequences:

>Translated_332_residues
MKLGWLILLTLLCALLSLGIGRYPVSATHSVMILLEPLTGPHGGIDEVQRQVILGVRVPRVLLAMGAGAALALCGAALQG
VFRNPLVDPHIIGVSSGAAFGGTLAILLSLPMAALLLSAFVFGMAALLLIFAITSAIARRNILSLVLAGVILSGFFSACV
SLLQYLADTEEKLPSIVFWLLGSFATADDNKLLMLFLPLLLAGGLLLALRWRINLLSLGDEDAAGLGINVERTRWLILTL
CAAIVAAQVAVSGSIGWVGLVIPHVARLLVGPDHRRLLPASMCLGALYMVLIDDLARTLSSSEIPLGILTALIGAPLFAL
LLRRAQLRGWHG
>Mature_332_residues
MKLGWLILLTLLCALLSLGIGRYPVSATHSVMILLEPLTGPHGGIDEVQRQVILGVRVPRVLLAMGAGAALALCGAALQG
VFRNPLVDPHIIGVSSGAAFGGTLAILLSLPMAALLLSAFVFGMAALLLIFAITSAIARRNILSLVLAGVILSGFFSACV
SLLQYLADTEEKLPSIVFWLLGSFATADDNKLLMLFLPLLLAGGLLLALRWRINLLSLGDEDAAGLGINVERTRWLILTL
CAAIVAAQVAVSGSIGWVGLVIPHVARLLVGPDHRRLLPASMCLGALYMVLIDDLARTLSSSEIPLGILTALIGAPLFAL
LLRRAQLRGWHG

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=339, Percent_Identity=38.9380530973451, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790741, Length=306, Percent_Identity=35.9477124183007, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788004, Length=278, Percent_Identity=37.0503597122302, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786805, Length=301, Percent_Identity=32.890365448505, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786347, Length=274, Percent_Identity=32.8467153284672, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1786804, Length=280, Percent_Identity=31.0714285714286, Blast_Score=84, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34973; Mature: 34973

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLGWLILLTLLCALLSLGIGRYPVSATHSVMILLEPLTGPHGGIDEVQRQVILGVRVPR
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
VLLAMGAGAALALCGAALQGVFRNPLVDPHIIGVSSGAAFGGTLAILLSLPMAALLLSAF
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
VFGMAALLLIFAITSAIARRNILSLVLAGVILSGFFSACVSLLQYLADTEEKLPSIVFWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSFATADDNKLLMLFLPLLLAGGLLLALRWRINLLSLGDEDAAGLGINVERTRWLILTL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHH
CAAIVAAQVAVSGSIGWVGLVIPHVARLLVGPDHRRLLPASMCLGALYMVLIDDLARTLS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSEIPLGILTALIGAPLFALLLRRAQLRGWHG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLGWLILLTLLCALLSLGIGRYPVSATHSVMILLEPLTGPHGGIDEVQRQVILGVRVPR
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
VLLAMGAGAALALCGAALQGVFRNPLVDPHIIGVSSGAAFGGTLAILLSLPMAALLLSAF
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
VFGMAALLLIFAITSAIARRNILSLVLAGVILSGFFSACVSLLQYLADTEEKLPSIVFWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSFATADDNKLLMLFLPLLLAGGLLLALRWRINLLSLGDEDAAGLGINVERTRWLILTL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHH
CAAIVAAQVAVSGSIGWVGLVIPHVARLLVGPDHRRLLPASMCLGALYMVLIDDLARTLS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSEIPLGILTALIGAPLFALLLRRAQLRGWHG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]