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The map label for this gene is ybhA [H]

Identifier: 157369549

GI number: 157369549

Start: 1435613

End: 1436437

Strand: Reverse

Name: ybhA [H]

Synonym: Spro_1306

Alternate gene names: 157369549

Gene position: 1436437-1435613 (Counterclockwise)

Preceding gene: 157369551

Following gene: 157369539

Centisome position: 26.36

GC content: 58.79

Gene sequence:

>825_bases
ATGAGCTACCGCGTCATTGCCCTCGATCTGGATGGCACCTTGCTGGACAACCAAAAACGCATTTTACCGCAGTCGCTGGC
AGCCCTGGCCCAGGCGCGTGCCGCCGGCGTCAAAGTAGTGGTAGTCACCGGTCGCCATCATGTGGCGATCCACCCGTTCT
ATCAGGCGCTGGAGATAGACACCCCGGCAATCTGCTGTAACGGCACCTATTTGTATGACTTCCAGCAGAAAAAAGTGCTG
GCGGCCGATCCGCTGGAAAAAGCTCAGGCCAAGCTGGTGTTGCAGATGCTGAAGCAAAGCGACATTCATGGCCTGATGTA
CGTGGACGACGCCATGCTGTATCAGGAGCCGAGCGGCCACGTCACCCGTTCATTGGCCTGGGCAGAAACCCTGCCGCCGG
CACAGCGCCCAACGCTGTTGCAGGTTAACAGCCTGGTTCAGGCAGCCGATGAGGCGCAGTCAATCTGGAAATTCGCCACC
TCGCACGCCGATATCCCTGCACTGCGCCGCTTCGCCGAAACGGTAGAAAAAGAGCTGGGGCTGGCCTGCGAATGGTCGTG
GCACGATCAGGTCGATATTGCCAAAGGCGGCAACAGCAAGGGGAAACGCCTGCAGCAATGGGTGGAGTCACAGGGTTTAA
GCATGAGCCAGGTGGTGGCCTTCGGGGATAACTACAACGATCTCAGCATGCTGGAAGCGGTTGGCCTGGGTGTCGCCATG
GGCAACGCCGATGACGCCATCAAACAACGCGCCGATCTGGTGATTGCCGATCACCTGCAGCCGGGTATTGCCGAAGTCAT
CCGCACTCGAGTCTTGGGTCAGTAA

Upstream 100 bases:

>100_bases
ACATCCGTGACGCGTTGCAGATGAAATCTGTGCGGTTTTATCCGTTGCTTATCCGGTGTACCATCAGTTTAATTTTGTTG
CTAACTATAATGAGATCCCT

Downstream 100 bases:

>100_bases
TGCCATTGCCCTCCCTGCCGGGAGGGCCGAATTCAACGTGCCTCGTGGCTGATTGACACGCTTTTGACCTGCGCATACAG
CCACTGCCCCGGCCGGATCG

Product: phosphotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSYRVIALDLDGTLLDNQKRILPQSLAALAQARAAGVKVVVVTGRHHVAIHPFYQALEIDTPAICCNGTYLYDFQQKKVL
AADPLEKAQAKLVLQMLKQSDIHGLMYVDDAMLYQEPSGHVTRSLAWAETLPPAQRPTLLQVNSLVQAADEAQSIWKFAT
SHADIPALRRFAETVEKELGLACEWSWHDQVDIAKGGNSKGKRLQQWVESQGLSMSQVVAFGDNYNDLSMLEAVGLGVAM
GNADDAIKQRADLVIADHLQPGIAEVIRTRVLGQ

Sequences:

>Translated_274_residues
MSYRVIALDLDGTLLDNQKRILPQSLAALAQARAAGVKVVVVTGRHHVAIHPFYQALEIDTPAICCNGTYLYDFQQKKVL
AADPLEKAQAKLVLQMLKQSDIHGLMYVDDAMLYQEPSGHVTRSLAWAETLPPAQRPTLLQVNSLVQAADEAQSIWKFAT
SHADIPALRRFAETVEKELGLACEWSWHDQVDIAKGGNSKGKRLQQWVESQGLSMSQVVAFGDNYNDLSMLEAVGLGVAM
GNADDAIKQRADLVIADHLQPGIAEVIRTRVLGQ
>Mature_273_residues
SYRVIALDLDGTLLDNQKRILPQSLAALAQARAAGVKVVVVTGRHHVAIHPFYQALEIDTPAICCNGTYLYDFQQKKVLA
ADPLEKAQAKLVLQMLKQSDIHGLMYVDDAMLYQEPSGHVTRSLAWAETLPPAQRPTLLQVNSLVQAADEAQSIWKFATS
HADIPALRRFAETVEKELGLACEWSWHDQVDIAKGGNSKGKRLQQWVESQGLSMSQVVAFGDNYNDLSMLEAVGLGVAMG
NADDAIKQRADLVIADHLQPGIAEVIRTRVLGQ

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates pyridoxalphosphate and erythrose 4-phosphate [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI1786982, Length=272, Percent_Identity=63.2352941176471, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI48994981, Length=256, Percent_Identity=26.953125, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87081741, Length=244, Percent_Identity=28.2786885245902, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001757
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR006380 [H]

Pfam domain/function: PF00702 Hydrolase; PF05116 S6PP [H]

EC number: NA

Molecular weight: Translated: 30078; Mature: 29947

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRVIALDLDGTLLDNQKRILPQSLAALAQARAAGVKVVVVTGRHHVAIHPFYQALEID
CCEEEEEEECCCCEECCCHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEECCHHHHHCCC
TPAICCNGTYLYDFQQKKVLAADPLEKAQAKLVLQMLKQSDIHGLMYVDDAMLYQEPSGH
CCEEEECCCEEEECCCCCEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHEEECCCCC
VTRSLAWAETLPPAQRPTLLQVNSLVQAADEAQSIWKFATSHADIPALRRFAETVEKELG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
LACEWSWHDQVDIAKGGNSKGKRLQQWVESQGLSMSQVVAFGDNYNDLSMLEAVGLGVAM
CEEEECCCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHEEECCCCCHHHHHHHHHHHEEE
GNADDAIKQRADLVIADHLQPGIAEVIRTRVLGQ
CCCHHHHHHHHCEEEEHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SYRVIALDLDGTLLDNQKRILPQSLAALAQARAAGVKVVVVTGRHHVAIHPFYQALEID
CEEEEEEECCCCEECCCHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEECCHHHHHCCC
TPAICCNGTYLYDFQQKKVLAADPLEKAQAKLVLQMLKQSDIHGLMYVDDAMLYQEPSGH
CCEEEECCCEEEECCCCCEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHEEECCCCC
VTRSLAWAETLPPAQRPTLLQVNSLVQAADEAQSIWKFATSHADIPALRRFAETVEKELG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
LACEWSWHDQVDIAKGGNSKGKRLQQWVESQGLSMSQVVAFGDNYNDLSMLEAVGLGVAM
CEEEECCCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHEEECCCCCHHHHHHHHHHHEEE
GNADDAIKQRADLVIADHLQPGIAEVIRTRVLGQ
CCCHHHHHHHHCEEEEHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665460; 8564363; 8905232; 9278503 [H]