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The map label for this gene is kdpA

Identifier: 157369491

GI number: 157369491

Start: 1374317

End: 1376005

Strand: Reverse

Name: kdpA

Synonym: Spro_1248

Alternate gene names: 157369491

Gene position: 1376005-1374317 (Counterclockwise)

Preceding gene: 157369492

Following gene: 157369490

Centisome position: 25.25

GC content: 60.09

Gene sequence:

>1689_bases
ATGGCAGCTTCAGCCTTTTTATTGATTGCCAGCTTTATGCTGGTGCTTTTGCTGCTGGCCCGGCCGTTAGGCAGTTTCCT
GGCGCGCCTGATCGAAGGTGAACCTTTACCCGCGCTGCGTCGGGTGGAGGCCGCCGTCTGGCGTTGCTGTGGCAATACCA
CCGCTGAAATGAACTGGTGGCAGTACGCGCTGGCAATCTTGTGGTTCAACCTGCTCGGCCTGGCGCTGTTGTTTGCGCTG
CTGATGACGCAAGGCTCGTTGCCGCTAAACCCGCAGGGTTTCCCTGGCCTGTCATGGGATTTGGCGTTCAATACTGCCGT
CAGCTTTGTCACCAACACCAACTGGCAGGCCTACAGCGGTGAAAGCACCCTCAGCTACCTCAGCCAGATGGCCGGGCTGG
CAGTGCAGAACTTCCTGTCTGCCGCTACCGGTATCGCCGTGGCCTTTGCGTTGATTCGCGCCTTCACCCGCCGTTCCAGC
GCCACCATAGGTAATGCCTGGATCGACGTGTTCCGTATAACGCTGTACGTGTTGCTGCCGATCTCGCTGCTGATCGCGCT
GTTCTTCGTCAGCCAGGGCACGCTGCAAAACTTCCTGCCTTACCTGCATATCAGCACGCTGGAAGGCGCGCAGCAGACGC
TGCCAATGGGGCCGGTTGCCTCTCAGGAAGCGATCAAGATGCTCGGCACCAACGGCGGCGGCTTCTTCGGCGTCAACTCG
GCTCATCCGTTCGAAAACCCGACCGTACTGACCAACTTTGTGCAGATGTTGGCGATCTTCCTGATCCCTTGTGCGCTGTG
CTTTTCCTTCGGCCAGGTGGCCGGTGAGAACCGTCAGGGCCATGCGCTGATCTGGGCGATGTCGCTGATCTTCGTGGTGG
CCGTCGTAGTGGTGATGTACGCCGAGCTGGCGGGTAACCCGCATCTGAGCGAATTGGGCAGTGCCAGCAACATCAATATG
GAAGGCAAGGAATCGCGCTTTGGCATTCTCGCCACCAGCATGTTCTCGGTGGTCACCACCGCAGCGTCCTGTGGGGCCGT
CAACGCCATGCATGACTCCTTCACCGCGCTGGGCGGCATGGTGCCCATGTGGCTGATGCAGATTGGTGAAGTGGTGTTCG
GCGGCGTCGGTTCCGGCCTGTACGGCATGCTGCTGTTCGTGCTGCTGACGGTGTTTATCGCTGGGTTGATGATTGGGCGT
ACCCCGGAATATCTGGGCAAAAAAATCGACGTCTATGACATGAAAATGACCGCGCTGGCGATCCTGGTCACGCCGACCCT
GGTGTTGCTGGGCAGCGCACTGGCCATATCTACCGACGTAGGCCGCGCCGGCATTCTTAACCCGGGTGCGCACGGTTTCA
GCGAAGTGCTGTATGCCCTGTCCTCCGCCGCCAATAACAACGGCAGCGCCTTTGGTGGGCTGAGCGTCAACACGCCGTTC
TACAACCTGCTGTTGGCCTTTGCCATGTTCGTCGGCCGCTTCGGGGTGATCCTGCCGGTGCTGGCAATCGCCGGTTCGCT
GTGCGCCAAGAAACGCCAGCCTGCGGGCAACGGGACCTTGCCAACCTACGGGCCGTTGTTTATCGGCCTGCTGGTCGGCA
CCGTGCTGCTGGTGGGCGCATTAACCTTCGTGCCTGCGCTGGCGCTGGGACCGGTGGCTGAGCATTTGCAACTTTGGCTG
ACCAAATAA

Upstream 100 bases:

>100_bases
GGAGGTGTCCTGTGAGTATCAGCGTTATTGGTGGTGCGCTGTTGGTCCTGCTGCTGTTGGGCTATCTGGTTTATGCCCTG
TTCAATGCGGAGGATTTCTG

Downstream 100 bases:

>100_bases
TCGACGTCATAGAGAGAGAATAAAAGATGACTCGCAAACAACGCGCGCTGTTTGAACCGGCACTGGTCCGTACCGCGCTG
ATCGATGCGCTGAAAAAGCT

Product: potassium-transporting ATPase subunit A

Products: NA

Alternate protein names: ATP phosphohydrolase [potassium-transporting] A chain; Potassium-binding and translocating subunit A; Potassium-translocating ATPase A chain

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MAASAFLLIASFMLVLLLLARPLGSFLARLIEGEPLPALRRVEAAVWRCCGNTTAEMNWWQYALAILWFNLLGLALLFAL
LMTQGSLPLNPQGFPGLSWDLAFNTAVSFVTNTNWQAYSGESTLSYLSQMAGLAVQNFLSAATGIAVAFALIRAFTRRSS
ATIGNAWIDVFRITLYVLLPISLLIALFFVSQGTLQNFLPYLHISTLEGAQQTLPMGPVASQEAIKMLGTNGGGFFGVNS
AHPFENPTVLTNFVQMLAIFLIPCALCFSFGQVAGENRQGHALIWAMSLIFVVAVVVVMYAELAGNPHLSELGSASNINM
EGKESRFGILATSMFSVVTTAASCGAVNAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMLLFVLLTVFIAGLMIGR
TPEYLGKKIDVYDMKMTALAILVTPTLVLLGSALAISTDVGRAGILNPGAHGFSEVLYALSSAANNNGSAFGGLSVNTPF
YNLLLAFAMFVGRFGVILPVLAIAGSLCAKKRQPAGNGTLPTYGPLFIGLLVGTVLLVGALTFVPALALGPVAEHLQLWL
TK

Sequences:

>Translated_562_residues
MAASAFLLIASFMLVLLLLARPLGSFLARLIEGEPLPALRRVEAAVWRCCGNTTAEMNWWQYALAILWFNLLGLALLFAL
LMTQGSLPLNPQGFPGLSWDLAFNTAVSFVTNTNWQAYSGESTLSYLSQMAGLAVQNFLSAATGIAVAFALIRAFTRRSS
ATIGNAWIDVFRITLYVLLPISLLIALFFVSQGTLQNFLPYLHISTLEGAQQTLPMGPVASQEAIKMLGTNGGGFFGVNS
AHPFENPTVLTNFVQMLAIFLIPCALCFSFGQVAGENRQGHALIWAMSLIFVVAVVVVMYAELAGNPHLSELGSASNINM
EGKESRFGILATSMFSVVTTAASCGAVNAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMLLFVLLTVFIAGLMIGR
TPEYLGKKIDVYDMKMTALAILVTPTLVLLGSALAISTDVGRAGILNPGAHGFSEVLYALSSAANNNGSAFGGLSVNTPF
YNLLLAFAMFVGRFGVILPVLAIAGSLCAKKRQPAGNGTLPTYGPLFIGLLVGTVLLVGALTFVPALALGPVAEHLQLWL
TK
>Mature_561_residues
AASAFLLIASFMLVLLLLARPLGSFLARLIEGEPLPALRRVEAAVWRCCGNTTAEMNWWQYALAILWFNLLGLALLFALL
MTQGSLPLNPQGFPGLSWDLAFNTAVSFVTNTNWQAYSGESTLSYLSQMAGLAVQNFLSAATGIAVAFALIRAFTRRSSA
TIGNAWIDVFRITLYVLLPISLLIALFFVSQGTLQNFLPYLHISTLEGAQQTLPMGPVASQEAIKMLGTNGGGFFGVNSA
HPFENPTVLTNFVQMLAIFLIPCALCFSFGQVAGENRQGHALIWAMSLIFVVAVVVVMYAELAGNPHLSELGSASNINME
GKESRFGILATSMFSVVTTAASCGAVNAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMLLFVLLTVFIAGLMIGRT
PEYLGKKIDVYDMKMTALAILVTPTLVLLGSALAISTDVGRAGILNPGAHGFSEVLYALSSAANNNGSAFGGLSVNTPFY
NLLLAFAMFVGRFGVILPVLAIAGSLCAKKRQPAGNGTLPTYGPLFIGLLVGTVLLVGALTFVPALALGPVAEHLQLWLT
K

Specific function: One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions

COG id: COG2060

COG function: function code P; K+-transporting ATPase, A chain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdpA family

Homologues:

Organism=Escherichia coli, GI1786915, Length=556, Percent_Identity=76.4388489208633, Blast_Score=854, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATKA_SERP5 (A8GB62)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477480.1
- STRING:   A8GB62
- GeneID:   5604266
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_1248
- eggNOG:   COG2060
- HOGENOM:   HBG291815
- OMA:   MSYLTQM
- ProtClustDB:   PRK05482
- BioCyc:   SPRO399741:SPRO_1248-MONOMER
- HAMAP:   MF_00275
- InterPro:   IPR004623
- PIRSF:   PIRSF001294
- TIGRFAMs:   TIGR00680

Pfam domain/function: PF03814 KdpA

EC number: =3.6.3.12

Molecular weight: Translated: 59633; Mature: 59502

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x23606cc0)-; HASH(0x218c2e60)-; HASH(0x206f1e0c)-; HASH(0x218e339c)-; HASH(0x238286f8)-; HASH(0x22f6d4f0)-; HASH(0x1f433f48)-; HASH(0x215656dc)-; HASH(0x2260a45c)-; HASH(0x23614fe4)-; HASH(0x2361f634)-; HASH(0x2383d5d8)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASAFLLIASFMLVLLLLARPLGSFLARLIEGEPLPALRRVEAAVWRCCGNTTAEMNWW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
QYALAILWFNLLGLALLFALLMTQGSLPLNPQGFPGLSWDLAFNTAVSFVTNTNWQAYSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCEECC
ESTLSYLSQMAGLAVQNFLSAATGIAVAFALIRAFTRRSSATIGNAWIDVFRITLYVLLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ISLLIALFFVSQGTLQNFLPYLHISTLEGAQQTLPMGPVASQEAIKMLGTNGGGFFGVNS
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCC
AHPFENPTVLTNFVQMLAIFLIPCALCFSFGQVAGENRQGHALIWAMSLIFVVAVVVVMY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
AELAGNPHLSELGSASNINMEGKESRFGILATSMFSVVTTAASCGAVNAMHDSFTALGGM
HHHCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VPMWLMQIGEVVFGGVGSGLYGMLLFVLLTVFIAGLMIGRTPEYLGKKIDVYDMKMTALA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEHHHHHHHH
ILVTPTLVLLGSALAISTDVGRAGILNPGAHGFSEVLYALSSAANNNGSAFGGLSVNTPF
HHHHHHHHHHCCHHHEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCCCCHH
YNLLLAFAMFVGRFGVILPVLAIAGSLCAKKRQPAGNGTLPTYGPLFIGLLVGTVLLVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LTFVPALALGPVAEHLQLWLTK
HHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
AASAFLLIASFMLVLLLLARPLGSFLARLIEGEPLPALRRVEAAVWRCCGNTTAEMNWW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
QYALAILWFNLLGLALLFALLMTQGSLPLNPQGFPGLSWDLAFNTAVSFVTNTNWQAYSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCEECC
ESTLSYLSQMAGLAVQNFLSAATGIAVAFALIRAFTRRSSATIGNAWIDVFRITLYVLLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ISLLIALFFVSQGTLQNFLPYLHISTLEGAQQTLPMGPVASQEAIKMLGTNGGGFFGVNS
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCC
AHPFENPTVLTNFVQMLAIFLIPCALCFSFGQVAGENRQGHALIWAMSLIFVVAVVVVMY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
AELAGNPHLSELGSASNINMEGKESRFGILATSMFSVVTTAASCGAVNAMHDSFTALGGM
HHHCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VPMWLMQIGEVVFGGVGSGLYGMLLFVLLTVFIAGLMIGRTPEYLGKKIDVYDMKMTALA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEHHHHHHHH
ILVTPTLVLLGSALAISTDVGRAGILNPGAHGFSEVLYALSSAANNNGSAFGGLSVNTPF
HHHHHHHHHHCCHHHEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCCCCHH
YNLLLAFAMFVGRFGVILPVLAIAGSLCAKKRQPAGNGTLPTYGPLFIGLLVGTVLLVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LTFVPALALGPVAEHLQLWLTK
HHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA