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The map label for this gene is ompR [H]

Identifier: 157369278

GI number: 157369278

Start: 1137313

End: 1138053

Strand: Reverse

Name: ompR [H]

Synonym: Spro_1035

Alternate gene names: 157369278

Gene position: 1138053-1137313 (Counterclockwise)

Preceding gene: 157369282

Following gene: 157369271

Centisome position: 20.89

GC content: 62.35

Gene sequence:

>741_bases
ATGAAACCTGCCGTATTGATCGTCGACGACGATCCTGCCATTTGTGACCTGCTCTGCGACGTCCTCAACGAGCATGTGTT
TAGCGTGCATGCCTGCCACCGGGGCAGCGAGGCGTTAACCTTACTCAGCCAGCAACCGGATATTGCTCTGGTGCTGCTTG
ATCTGATCCTGCCGGACACCAACGGCCTGCTGGTGTTGCAGCAGATCCACCGTTTGCGCCCGGATCTGCCGGTGGTGATG
TTGACCGGCCTCGGCTCCGAGTCCGACGTGGTGGTCGGTCTGGAAATGGGGGCCGACGACTACATTGCCAAACCCTTTAA
CCCACGCGTGGTGGTCGCCCGCGCCAAGGCGGTGTTACGCCGTACCGGTGCGCTGGCGCTGGAGCCGGCCACCGCCGGTC
GGAACAAACCCGAAGGCTGGCAGTTCAACGGCTGGTGCCTGGATACTGCCCGCTGCACCCTACACAACCCGCAGCGACAA
CCGGTCGATCTGACCCAGGGCGAATACGGCCTGCTGCTGGCGCTGGTACAGCACGCGCGCAAAGTACTGACCCGCGATCG
CCTGCTTGAGCTGACCCACAGCGAAACGCTGGAGGTGTTCGATCGCACCATCGACGTGCTGATCATGCGGCTACGACGCA
AGATCGAGATTAATCCGCATCAACCCGAGTTGATCCGCACCATTCGCGGGCTGGGCTATGTTTTCGCCGCCGACGTCAGC
CAGCCGGTGGCTGCCGCCTGA

Upstream 100 bases:

>100_bases
CACACCGGCTACCGCTTATTAATTAGCCATCGGGTACACTGCATTTAACCAGTTAACTTGTTGATAACATTTTCCGCATC
CTAAAATCCGGAGAGCAGCG

Downstream 100 bases:

>100_bases
TATAATCCTGCAGTTCCGACAAGGGGCGTGCGCCATCGATCGCGTTGGCGCACAGTAGATTGAACCGCGCACAGGCATGC
GCCAATTGCAGCGTCTCTGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKPAVLIVDDDPAICDLLCDVLNEHVFSVHACHRGSEALTLLSQQPDIALVLLDLILPDTNGLLVLQQIHRLRPDLPVVM
LTGLGSESDVVVGLEMGADDYIAKPFNPRVVVARAKAVLRRTGALALEPATAGRNKPEGWQFNGWCLDTARCTLHNPQRQ
PVDLTQGEYGLLLALVQHARKVLTRDRLLELTHSETLEVFDRTIDVLIMRLRRKIEINPHQPELIRTIRGLGYVFAADVS
QPVAAA

Sequences:

>Translated_246_residues
MKPAVLIVDDDPAICDLLCDVLNEHVFSVHACHRGSEALTLLSQQPDIALVLLDLILPDTNGLLVLQQIHRLRPDLPVVM
LTGLGSESDVVVGLEMGADDYIAKPFNPRVVVARAKAVLRRTGALALEPATAGRNKPEGWQFNGWCLDTARCTLHNPQRQ
PVDLTQGEYGLLLALVQHARKVLTRDRLLELTHSETLEVFDRTIDVLIMRLRRKIEINPHQPELIRTIRGLGYVFAADVS
QPVAAA
>Mature_246_residues
MKPAVLIVDDDPAICDLLCDVLNEHVFSVHACHRGSEALTLLSQQPDIALVLLDLILPDTNGLLVLQQIHRLRPDLPVVM
LTGLGSESDVVVGLEMGADDYIAKPFNPRVVVARAKAVLRRTGALALEPATAGRNKPEGWQFNGWCLDTARCTLHNPQRQ
PVDLTQGEYGLLLALVQHARKVLTRDRLLELTHSETLEVFDRTIDVLIMRLRRKIEINPHQPELIRTIRGLGYVFAADVS
QPVAAA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=242, Percent_Identity=39.2561983471074, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1790863, Length=238, Percent_Identity=36.5546218487395, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1786599, Length=240, Percent_Identity=36.6666666666667, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788394, Length=244, Percent_Identity=37.2950819672131, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1787229, Length=241, Percent_Identity=36.0995850622407, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1790860, Length=240, Percent_Identity=34.5833333333333, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=38.135593220339, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=32.034632034632, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI145693140, Length=242, Percent_Identity=33.4710743801653, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082012, Length=235, Percent_Identity=31.063829787234, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=32.7586206896552, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786911, Length=235, Percent_Identity=32.7659574468085, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789402, Length=234, Percent_Identity=31.1965811965812, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790552, Length=243, Percent_Identity=30.8641975308642, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1788905, Length=107, Percent_Identity=33.6448598130841, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27213; Mature: 27213

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPAVLIVDDDPAICDLLCDVLNEHVFSVHACHRGSEALTLLSQQPDIALVLLDLILPDT
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHEEHHHCCCC
NGLLVLQQIHRLRPDLPVVMLTGLGSESDVVVGLEMGADDYIAKPFNPRVVVARAKAVLR
CCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCEEEHHHHHHHHH
RTGALALEPATAGRNKPEGWQFNGWCLDTARCTLHNPQRQPVDLTQGEYGLLLALVQHAR
HCCCEEECCCCCCCCCCCCCEECCEEEECCEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
KVLTRDRLLELTHSETLEVFDRTIDVLIMRLRRKIEINPHQPELIRTIRGLGYVFAADVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEECCC
QPVAAA
CCCCCC
>Mature Secondary Structure
MKPAVLIVDDDPAICDLLCDVLNEHVFSVHACHRGSEALTLLSQQPDIALVLLDLILPDT
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHEEHHHCCCC
NGLLVLQQIHRLRPDLPVVMLTGLGSESDVVVGLEMGADDYIAKPFNPRVVVARAKAVLR
CCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCEEEHHHHHHHHH
RTGALALEPATAGRNKPEGWQFNGWCLDTARCTLHNPQRQPVDLTQGEYGLLLALVQHAR
HCCCEEECCCCCCCCCCCCCEECCEEEECCEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
KVLTRDRLLELTHSETLEVFDRTIDVLIMRLRRKIEINPHQPELIRTIRGLGYVFAADVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEECCC
QPVAAA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]