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The map label for this gene is yhcS [C]

Identifier: 157369242

GI number: 157369242

Start: 1102272

End: 1103180

Strand: Reverse

Name: yhcS [C]

Synonym: Spro_0999

Alternate gene names: 157369242

Gene position: 1103180-1102272 (Counterclockwise)

Preceding gene: 157369248

Following gene: 157369239

Centisome position: 20.25

GC content: 63.04

Gene sequence:

>909_bases
ATGTTCACTGATTTGAACGATCTGTTTTACTTCGCCGCCGTGGTCGATCACCAGGGATTCGCCCCCGCCAGCCGTGCACT
GGGCATTCCCAAGTCCAAACTGAGCCGCCGTGTGGCACTGCTGGAAGAACGTCTGGGCGTGCGCCTGATCCAACGCTCAA
CGCGGCGTTTCTCCGTCACCGACGTCGGCCAGAACTACTATGCACACTGTAAGGCCATGTTGGTGGAGGCCGATGCGGCG
CAGCAGGCGATCGAACAAACCCGTGCCGAACCCTGCGGCACGGTGCGCATGTCCTGCCCGGTGGCGATCCTGCATACCCG
TGTCGGCAGCATGGTGGCGGCCTTTATGGCCGATTATCCGAAAGTCACGGTACACCTGGACGCCACCAACCGCCGGGTAG
ATGTGGTGGGGGAAGGGCTGGATCTGGCGATCCGCGTGCGGCCACCGCCGCTGGAAGACAGCGATCTGGTGCTGAAGATC
CTGGCGCAGCGCACCTGGTGTATCGCCGCCAGCCCGGCACTGGTGCGCACCCTCGGTCCGGTGCAACGACCGGAGGATCT
GCATAAGTATCCCACGCTCGATCTCGGGCCTGCGCGCGCACAACACCTGTGGCAGTTGACCGGGCCGGACGGCGAAAAAG
TGGAATGGGAACACAGGCCACGACTGGTTACCGACGATATGCTGATGTTGCGTACCGCGGCGATTGCCGGCGCCGGTATT
GTGCAACTGCCGTCGATGATGATGCGCGACGACATGTTGCGCGGCGAGCTGGTGCAACTGTTACCCGGCTGGCAGCCACA
GGGCGGCGTGGTGCATGCGGTTTACCCGTCACGCCGTGGGCTATTGCCCGCGGTACGGCTGCTGCTCGACTATCTGGCGC
AGCAGTTCGCGACTATCGAAGAAGAGTGA

Upstream 100 bases:

>100_bases
ACCTTAGGTTGATGCCAGAAGTTTAATCCAACGCTATTTGCTGCAGTAGTAGGCAAGATGTACACTCAGCGTTCTATAAA
TGGAACGATAAGGACAGACG

Downstream 100 bases:

>100_bases
TCAACCGGTGATTTCGATGGCGTTACCGTCCGGATCGCGGATGATCGCTTCGTAAAAACCATCGCCGGTCCAGCGTGGCG
GCGCTTGCAGGATCCCCTCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MFTDLNDLFYFAAVVDHQGFAPASRALGIPKSKLSRRVALLEERLGVRLIQRSTRRFSVTDVGQNYYAHCKAMLVEADAA
QQAIEQTRAEPCGTVRMSCPVAILHTRVGSMVAAFMADYPKVTVHLDATNRRVDVVGEGLDLAIRVRPPPLEDSDLVLKI
LAQRTWCIAASPALVRTLGPVQRPEDLHKYPTLDLGPARAQHLWQLTGPDGEKVEWEHRPRLVTDDMLMLRTAAIAGAGI
VQLPSMMMRDDMLRGELVQLLPGWQPQGGVVHAVYPSRRGLLPAVRLLLDYLAQQFATIEEE

Sequences:

>Translated_302_residues
MFTDLNDLFYFAAVVDHQGFAPASRALGIPKSKLSRRVALLEERLGVRLIQRSTRRFSVTDVGQNYYAHCKAMLVEADAA
QQAIEQTRAEPCGTVRMSCPVAILHTRVGSMVAAFMADYPKVTVHLDATNRRVDVVGEGLDLAIRVRPPPLEDSDLVLKI
LAQRTWCIAASPALVRTLGPVQRPEDLHKYPTLDLGPARAQHLWQLTGPDGEKVEWEHRPRLVTDDMLMLRTAAIAGAGI
VQLPSMMMRDDMLRGELVQLLPGWQPQGGVVHAVYPSRRGLLPAVRLLLDYLAQQFATIEEE
>Mature_302_residues
MFTDLNDLFYFAAVVDHQGFAPASRALGIPKSKLSRRVALLEERLGVRLIQRSTRRFSVTDVGQNYYAHCKAMLVEADAA
QQAIEQTRAEPCGTVRMSCPVAILHTRVGSMVAAFMADYPKVTVHLDATNRRVDVVGEGLDLAIRVRPPPLEDSDLVLKI
LAQRTWCIAASPALVRTLGPVQRPEDLHKYPTLDLGPARAQHLWQLTGPDGEKVEWEHRPRLVTDDMLMLRTAAIAGAGI
VQLPSMMMRDDMLRGELVQLLPGWQPQGGVVHAVYPSRRGLLPAVRLLLDYLAQQFATIEEE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=29.8305084745763, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI145693193, Length=284, Percent_Identity=27.8169014084507, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=29.2929292929293, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787128, Length=293, Percent_Identity=25.938566552901, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=29.3918918918919, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=24.6575342465753, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787589, Length=297, Percent_Identity=25.9259259259259, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789173, Length=259, Percent_Identity=27.027027027027, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI157672245, Length=159, Percent_Identity=30.8176100628931, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790208, Length=210, Percent_Identity=28.0952380952381, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787601, Length=167, Percent_Identity=24.5508982035928, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33572; Mature: 33572

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTDLNDLFYFAAVVDHQGFAPASRALGIPKSKLSRRVALLEERLGVRLIQRSTRRFSVT
CCCCHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
DVGQNYYAHCKAMLVEADAAQQAIEQTRAEPCGTVRMSCPVAILHTRVGSMVAAFMADYP
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCC
KVTVHLDATNRRVDVVGEGLDLAIRVRPPPLEDSDLVLKILAQRTWCIAASPALVRTLGP
EEEEEEECCCCEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHEEECCHHHHHHHCC
VQRPEDLHKYPTLDLGPARAQHLWQLTGPDGEKVEWEHRPRLVTDDMLMLRTAAIAGAGI
CCCCHHHHHCCCCCCCHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCH
VQLPSMMMRDDMLRGELVQLLPGWQPQGGVVHAVYPSRRGLLPAVRLLLDYLAQQFATIE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
EE
CC
>Mature Secondary Structure
MFTDLNDLFYFAAVVDHQGFAPASRALGIPKSKLSRRVALLEERLGVRLIQRSTRRFSVT
CCCCHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
DVGQNYYAHCKAMLVEADAAQQAIEQTRAEPCGTVRMSCPVAILHTRVGSMVAAFMADYP
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCC
KVTVHLDATNRRVDVVGEGLDLAIRVRPPPLEDSDLVLKILAQRTWCIAASPALVRTLGP
EEEEEEECCCCEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHEEECCHHHHHHHCC
VQRPEDLHKYPTLDLGPARAQHLWQLTGPDGEKVEWEHRPRLVTDDMLMLRTAAIAGAGI
CCCCHHHHHCCCCCCCHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCH
VQLPSMMMRDDMLRGELVQLLPGWQPQGGVVHAVYPSRRGLLPAVRLLLDYLAQQFATIE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
EE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]