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The map label for this gene is mtnK

Identifier: 157369191

GI number: 157369191

Start: 1043623

End: 1044822

Strand: Direct

Name: mtnK

Synonym: Spro_0946

Alternate gene names: 157369191

Gene position: 1043623-1044822 (Clockwise)

Preceding gene: 157369189

Following gene: 157369195

Centisome position: 19.15

GC content: 56.0

Gene sequence:

>1200_bases
ATGTCACATTATCGTACGTTTACTGCTGCTGATGCCGTTGAATATGCTCGTCAATACGGGCAGTTAGCCGATCCACAGGC
GCTGGTAAGCGCTGACGAGATTGGTGACGGCAATCTGAACCTGGTGTTCAAGATCCGCGATCGTGACGGCGTTAGCCGGG
TGATCGTCAAACAGGCGCTGCCGTATGTACGTTGTGTGGGCGAATCCTGGCCGCTAACGCTTGATCGGGCGCGCATTGAA
GCGGAAACCCTGTTGATTCACGGCGGTTTTTGCCCAAGGCATACGGTAAAGGTACTCCATCACGATGCCGAATTGGCGGT
GATGGTGCAGGAAGATCTTTCGGATCATCACATCTGGCGAAGCGAATTGGTCAAGGGGCACTATTACCCCTTGGCGGCAG
GGCAACTGGCAGAATATTTGGCGCAAACCCTGTTCCATACTTCCGATTTTTATCAGACGGCGCAGGAGAAAAAGGCGGAA
GTTAGTCGCTTTAGCAACCCCGAACTGTGCCAGATCACCGAAGATCTGTTCTTTACCGATCCCTATATCGATCATGAGCG
TAATCAGTTTGATCCGGCGCTGTTGCCGCAGGTGCTTGAACTGCGTAACGATGCGGCACTCAGGCTGGCGGTCGCCGGGC
TGAAGCATCGTTTCCTGAGCAAGGCGGAAGCGTTGTTGCACGGGGATATTCACAGTGGTTCGGTTTTTGTTGCAGAAGGC
AAGCTGAAGGCGATCGACGCCGAGTTCGGCTTCTATGGCCCGATCGGTTTTGACGTCGGTACCGCGCTGGGTAATCTGTT
ATTGAATTACTGCGGTCTACCGGGCCTGTTCGGGCCGCGCGACGCCGCTGCCGGGCGTGAACAACGTCTGCAGGATGTGC
GCGAGCTGTGGTTGATTTTCGCCGATCGCTTCCTGGCATTGTGCCACCAACAGACCCGCGAAGCGGCACTGGCGGTGCCG
GGTTATGCCGAACAGTTCCTGCAGCAGGTGTGGACAGATGCCGTCGGCTACTGCGGCAGTGAGTTGATCCGCCGTACTAT
CGGTCTGGCGCACGTTGCCGATCTGGACAGTATCAGTGACGCCGAGATGCGTGCCGAATGTCAGCGTAATGCTTTGGGGT
TGGGCCGTGCGTTGATTGTGAATGCGCCGCAGATTGAGCATATCGATGCGTTGTTGGCGCGTATTCGCCAGAACGGTTAA

Upstream 100 bases:

>100_bases
TATTCTGCCAACATGACTTCCGGATGTATAGACGTCCAAATGCTTTTACGTCTAAAAAATATAATCGCTGGGTCAGTGAG
AAAGATTAAAGGGGTTGGGG

Downstream 100 bases:

>100_bases
ATCTCCTGGATACCGTGAAAAAAGGGTGCTCATGGATCCGTCGTCAACAACCAACAGGCGGGGTGAACCCCGCCGTTGGG
TTGCCTTACCCTTCGGTTTC

Product: methylthioribose kinase

Products: NA

Alternate protein names: MTR kinase

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSHYRTFTAADAVEYARQYGQLADPQALVSADEIGDGNLNLVFKIRDRDGVSRVIVKQALPYVRCVGESWPLTLDRARIE
AETLLIHGGFCPRHTVKVLHHDAELAVMVQEDLSDHHIWRSELVKGHYYPLAAGQLAEYLAQTLFHTSDFYQTAQEKKAE
VSRFSNPELCQITEDLFFTDPYIDHERNQFDPALLPQVLELRNDAALRLAVAGLKHRFLSKAEALLHGDIHSGSVFVAEG
KLKAIDAEFGFYGPIGFDVGTALGNLLLNYCGLPGLFGPRDAAAGREQRLQDVRELWLIFADRFLALCHQQTREAALAVP
GYAEQFLQQVWTDAVGYCGSELIRRTIGLAHVADLDSISDAEMRAECQRNALGLGRALIVNAPQIEHIDALLARIRQNG

Sequences:

>Translated_399_residues
MSHYRTFTAADAVEYARQYGQLADPQALVSADEIGDGNLNLVFKIRDRDGVSRVIVKQALPYVRCVGESWPLTLDRARIE
AETLLIHGGFCPRHTVKVLHHDAELAVMVQEDLSDHHIWRSELVKGHYYPLAAGQLAEYLAQTLFHTSDFYQTAQEKKAE
VSRFSNPELCQITEDLFFTDPYIDHERNQFDPALLPQVLELRNDAALRLAVAGLKHRFLSKAEALLHGDIHSGSVFVAEG
KLKAIDAEFGFYGPIGFDVGTALGNLLLNYCGLPGLFGPRDAAAGREQRLQDVRELWLIFADRFLALCHQQTREAALAVP
GYAEQFLQQVWTDAVGYCGSELIRRTIGLAHVADLDSISDAEMRAECQRNALGLGRALIVNAPQIEHIDALLARIRQNG
>Mature_398_residues
SHYRTFTAADAVEYARQYGQLADPQALVSADEIGDGNLNLVFKIRDRDGVSRVIVKQALPYVRCVGESWPLTLDRARIEA
ETLLIHGGFCPRHTVKVLHHDAELAVMVQEDLSDHHIWRSELVKGHYYPLAAGQLAEYLAQTLFHTSDFYQTAQEKKAEV
SRFSNPELCQITEDLFFTDPYIDHERNQFDPALLPQVLELRNDAALRLAVAGLKHRFLSKAEALLHGDIHSGSVFVAEGK
LKAIDAEFGFYGPIGFDVGTALGNLLLNYCGLPGLFGPRDAAAGREQRLQDVRELWLIFADRFLALCHQQTREAALAVPG
YAEQFLQQVWTDAVGYCGSELIRRTIGLAHVADLDSISDAEMRAECQRNALGLGRALIVNAPQIEHIDALLARIRQNG

Specific function: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate

COG id: COG4857

COG function: function code R; Predicted kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methylthioribose kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNK_SERP5 (A8GAB2)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477180.1
- ProteinModelPortal:   A8GAB2
- SMR:   A8GAB2
- STRING:   A8GAB2
- GeneID:   5603764
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0946
- eggNOG:   COG4857
- HOGENOM:   HBG305135
- OMA:   ALPYVRL
- ProtClustDB:   PRK09550
- BioCyc:   SPRO399741:SPRO_0946-MONOMER
- HAMAP:   MF_01683
- InterPro:   IPR002575
- InterPro:   IPR011009
- InterPro:   IPR009212
- PIRSF:   PIRSF031134
- TIGRFAMs:   TIGR01767

Pfam domain/function: PF01636 APH; SSF56112 Kinase_like

EC number: =2.7.1.100

Molecular weight: Translated: 44470; Mature: 44339

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: BINDING 40-40 BINDING 57-57 BINDING 229-229 BINDING 344-344

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHYRTFTAADAVEYARQYGQLADPQALVSADEIGDGNLNLVFKIRDRDGVSRVIVKQAL
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHC
PYVRCVGESWPLTLDRARIEAETLLIHGGFCPRHTVKVLHHDAELAVMVQEDLSDHHIWR
HHHHHCCCCCCCCHHHHHHCEEEEEEECCCCCHHHHHHHHCCCCEEEEEHHCCCHHHHHH
SELVKGHYYPLAAGQLAEYLAQTLFHTSDFYQTAQEKKAEVSRFSNPELCQITEDLFFTD
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PYIDHERNQFDPALLPQVLELRNDAALRLAVAGLKHRFLSKAEALLHGDIHSGSVFVAEG
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
KLKAIDAEFGFYGPIGFDVGTALGNLLLNYCGLPGLFGPRDAAAGREQRLQDVRELWLIF
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ADRFLALCHQQTREAALAVPGYAEQFLQQVWTDAVGYCGSELIRRTIGLAHVADLDSISD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
AEMRAECQRNALGLGRALIVNAPQIEHIDALLARIRQNG
HHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SHYRTFTAADAVEYARQYGQLADPQALVSADEIGDGNLNLVFKIRDRDGVSRVIVKQAL
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHC
PYVRCVGESWPLTLDRARIEAETLLIHGGFCPRHTVKVLHHDAELAVMVQEDLSDHHIWR
HHHHHCCCCCCCCHHHHHHCEEEEEEECCCCCHHHHHHHHCCCCEEEEEHHCCCHHHHHH
SELVKGHYYPLAAGQLAEYLAQTLFHTSDFYQTAQEKKAEVSRFSNPELCQITEDLFFTD
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PYIDHERNQFDPALLPQVLELRNDAALRLAVAGLKHRFLSKAEALLHGDIHSGSVFVAEG
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
KLKAIDAEFGFYGPIGFDVGTALGNLLLNYCGLPGLFGPRDAAAGREQRLQDVRELWLIF
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ADRFLALCHQQTREAALAVPGYAEQFLQQVWTDAVGYCGSELIRRTIGLAHVADLDSISD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
AEMRAECQRNALGLGRALIVNAPQIEHIDALLARIRQNG
HHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA