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The map label for this gene is iucA [H]

Identifier: 157369167

GI number: 157369167

Start: 1022806

End: 1024551

Strand: Reverse

Name: iucA [H]

Synonym: Spro_0922

Alternate gene names: 157369167

Gene position: 1024551-1022806 (Counterclockwise)

Preceding gene: 157369170

Following gene: 157369166

Centisome position: 18.8

GC content: 59.62

Gene sequence:

>1746_bases
ATGACAATCCAGTTTGAAACCGCGACGACCGACGTGGCTGCACAATGTTTTCTCAACGCATTGATGCGTGAAACCCGGGA
CTGGCAAATCGTTCCGGCGGCCAGCCACCAACAGTATCCGCAACTGCACATTCCACTTTCGCCTTCTCAGGCTATTCGCA
TCGCTTTACGCCATACCTCCCCCACTCAGCATCACCAGTACCTGTTCCCCGCTTATCTGTATCAGCAGGATGACGGTGCA
GGGGTTGCGCTGAGCGTGGAACAGCTTATCTCCTTGCTGTTGGAAAAACCGGCGGTGAAAGGCGAATTGTCCGATGACGT
GGTGGCCCGTTTCCGCCAGCGTGTACTGGAAAGTCATGAAAATACCCAGCAGGCGATCAATATCCGTCTGGACTGGCCTG
CGCTGCGCGACAAGCCGCTGAACTTCGCCCAGGCGGAACAGGGGCTGCTGGTAGGGCACGCCTTTCACCCGGCACCGAAG
TCTCATGAGCCATTCAACCATCAGCAGGCGCACCGCTATCTGCCGGATTTTGCCGCCAGCTTCCCGCTGCGTTGGTTTGC
CGTCGATAAACGCCAACTGTGCGGTGACAGCCTGAATCTGACGCTGCAGCAGCGCCTGCAACGTTTTGCCGCCGAAAGTG
CCCCACAGCTGTTGGCACACTTTAGCGATAACGTCTGGCTGCTACCGATGCATCCGTGGCAGGCCGACCATTTACTGACG
CAGAACTGGTGCCAGGATCTGGTGACCCAGGGGCTGCTGCAGGATCTGGGCGAAGCCGGCGAACGCTGGCTGCCTACCAG
TTCTTCACGCTCGCTGTACAGCGCCAGTAACCGTGACATGATCAAATTCTCCCTCAGCGTGCGCCTGACCAACTCGGTGC
GCACCCTGTCGGTAAAAGAAGTGAAGCGCGGGATCCGTCTGGCACGTCTGGCGCAAACCCCGCGCTGGCAACAGTTGCAG
GCGCGCTATCCGACCTTCCGCGTAATGCAGGAAGACGGCTGGGCCGGTCTTCGCTCGGCAGACGGCACCGTCCAGGAAGA
AAGCCTGATGGCACTGCGCGATAACCTGCTGTTCGACCAGCCACAAAGCCAGACCAACGTGCTGGTGACCCTGACCCAGG
CCGCGCCGGATGGCGGCGACAGCCTGCTGGCTGCAGCGGTACGCCGTTTGGCCAGCCGCCTGAATCTGCCGTTGCAACAA
GCCGCCCACACCTGGCTGGATGCCTACTGCCAACAGGTGTTGCTGCCGCTGTTCAGTACCGAAGCCGATTACGGGCTGGT
GCTGCTGGCTCACCAGCAAAACATTCTGGTAGAGATGCAGCAGGACCTGCCGATCGGCATGCTGTATCGCGACTGTCAGG
GCAGTGGCTTTACCCGTGACGCCGGCCCCTGGCTGGAAGAAATTGGCGAAGCCGATGCGGAAAACCGCTTCAGCGAGCAA
CAGTTGCTGCGCTACTTCCCTTACTACCTGCTGGTGAACTCCAGCCTGGCAGTCACCGCCGCACTGGCTGCGGCCGGTTT
CGACAGTGAAGAGGCATTGATGGCCCGGGTACGCGACGCACTGAGCGGCCTGCGCGCCAACGCCAAAAACACCCTGTGCC
TGGACTACGTGCTCGACAGCAGCCACTGGAACTGCAAAGGCAACTTCTTCTGTTACCTGCACGACCATAACGAAAACACC
ATCGTTGATCCGGCGGTGATTTACTTTGATTTCGTTAACCCGCTGCGCCAGGGGGCTACCCAATGA

Upstream 100 bases:

>100_bases
TGTTCAATTCATTGAAAAATTGTATCATAGGATGATTGATAACAATAAATATTATTGATATAAGAATCATTCTCAATTGA
TTCAACAGTGAAATGGGATC

Downstream 100 bases:

>100_bases
TGCCGCACGCCAAACTGATGCATGCCAGCAGCGGTTTTCGTTGCGAACGGCTGGAACGGGAGTTGCAGCTAGGTCTCGGT
CTCGACGGTAGCGCCGTGCT

Product: IucA/IucC family protein

Products: ADP; phosphate; aerobactin

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MTIQFETATTDVAAQCFLNALMRETRDWQIVPAASHQQYPQLHIPLSPSQAIRIALRHTSPTQHHQYLFPAYLYQQDDGA
GVALSVEQLISLLLEKPAVKGELSDDVVARFRQRVLESHENTQQAINIRLDWPALRDKPLNFAQAEQGLLVGHAFHPAPK
SHEPFNHQQAHRYLPDFAASFPLRWFAVDKRQLCGDSLNLTLQQRLQRFAAESAPQLLAHFSDNVWLLPMHPWQADHLLT
QNWCQDLVTQGLLQDLGEAGERWLPTSSSRSLYSASNRDMIKFSLSVRLTNSVRTLSVKEVKRGIRLARLAQTPRWQQLQ
ARYPTFRVMQEDGWAGLRSADGTVQEESLMALRDNLLFDQPQSQTNVLVTLTQAAPDGGDSLLAAAVRRLASRLNLPLQQ
AAHTWLDAYCQQVLLPLFSTEADYGLVLLAHQQNILVEMQQDLPIGMLYRDCQGSGFTRDAGPWLEEIGEADAENRFSEQ
QLLRYFPYYLLVNSSLAVTAALAAAGFDSEEALMARVRDALSGLRANAKNTLCLDYVLDSSHWNCKGNFFCYLHDHNENT
IVDPAVIYFDFVNPLRQGATQ

Sequences:

>Translated_581_residues
MTIQFETATTDVAAQCFLNALMRETRDWQIVPAASHQQYPQLHIPLSPSQAIRIALRHTSPTQHHQYLFPAYLYQQDDGA
GVALSVEQLISLLLEKPAVKGELSDDVVARFRQRVLESHENTQQAINIRLDWPALRDKPLNFAQAEQGLLVGHAFHPAPK
SHEPFNHQQAHRYLPDFAASFPLRWFAVDKRQLCGDSLNLTLQQRLQRFAAESAPQLLAHFSDNVWLLPMHPWQADHLLT
QNWCQDLVTQGLLQDLGEAGERWLPTSSSRSLYSASNRDMIKFSLSVRLTNSVRTLSVKEVKRGIRLARLAQTPRWQQLQ
ARYPTFRVMQEDGWAGLRSADGTVQEESLMALRDNLLFDQPQSQTNVLVTLTQAAPDGGDSLLAAAVRRLASRLNLPLQQ
AAHTWLDAYCQQVLLPLFSTEADYGLVLLAHQQNILVEMQQDLPIGMLYRDCQGSGFTRDAGPWLEEIGEADAENRFSEQ
QLLRYFPYYLLVNSSLAVTAALAAAGFDSEEALMARVRDALSGLRANAKNTLCLDYVLDSSHWNCKGNFFCYLHDHNENT
IVDPAVIYFDFVNPLRQGATQ
>Mature_580_residues
TIQFETATTDVAAQCFLNALMRETRDWQIVPAASHQQYPQLHIPLSPSQAIRIALRHTSPTQHHQYLFPAYLYQQDDGAG
VALSVEQLISLLLEKPAVKGELSDDVVARFRQRVLESHENTQQAINIRLDWPALRDKPLNFAQAEQGLLVGHAFHPAPKS
HEPFNHQQAHRYLPDFAASFPLRWFAVDKRQLCGDSLNLTLQQRLQRFAAESAPQLLAHFSDNVWLLPMHPWQADHLLTQ
NWCQDLVTQGLLQDLGEAGERWLPTSSSRSLYSASNRDMIKFSLSVRLTNSVRTLSVKEVKRGIRLARLAQTPRWQQLQA
RYPTFRVMQEDGWAGLRSADGTVQEESLMALRDNLLFDQPQSQTNVLVTLTQAAPDGGDSLLAAAVRRLASRLNLPLQQA
AHTWLDAYCQQVLLPLFSTEADYGLVLLAHQQNILVEMQQDLPIGMLYRDCQGSGFTRDAGPWLEEIGEADAENRFSEQQ
LLRYFPYYLLVNSSLAVTAALAAAGFDSEEALMARVRDALSGLRANAKNTLCLDYVLDSSHWNCKGNFFCYLHDHNENTI
VDPAVIYFDFVNPLRQGATQ

Specific function: Unknown

COG id: COG4264

COG function: function code Q; Siderophore synthetase component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iucA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007310
- InterPro:   IPR022770 [H]

Pfam domain/function: PF06276 FhuF; PF04183 IucA_IucC [H]

EC number: 6.3.2.27

Molecular weight: Translated: 65619; Mature: 65488

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQFETATTDVAAQCFLNALMRETRDWQIVPAASHQQYPQLHIPLSPSQAIRIALRHTS
CEEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCCCCEEEEEEECCC
PTQHHQYLFPAYLYQQDDGAGVALSVEQLISLLLEKPAVKGELSDDVVARFRQRVLESHE
CCCCCCEECHHHEEECCCCCCEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
NTQQAINIRLDWPALRDKPLNFAQAEQGLLVGHAFHPAPKSHEPFNHQQAHRYLPDFAAS
CCCCEEEEEEECCCCCCCCCCHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHCHHHHHH
FPLRWFAVDKRQLCGDSLNLTLQQRLQRFAAESAPQLLAHFSDNVWLLPMHPWQADHLLT
CCEEEEEECHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
QNWCQDLVTQGLLQDLGEAGERWLPTSSSRSLYSASNRDMIKFSLSVRLTNSVRTLSVKE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEHHH
VKRGIRLARLAQTPRWQQLQARYPTFRVMQEDGWAGLRSADGTVQEESLMALRDNLLFDQ
HHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
PQSQTNVLVTLTQAAPDGGDSLLAAAVRRLASRLNLPLQQAAHTWLDAYCQQVLLPLFST
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
EADYGLVLLAHQQNILVEMQQDLPIGMLYRDCQGSGFTRDAGPWLEEIGEADAENRFSEQ
CCCCCEEEEEECCCEEHEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHCCCCHHHHCCHH
QLLRYFPYYLLVNSSLAVTAALAAAGFDSEEALMARVRDALSGLRANAKNTLCLDYVLDS
HHHHHCCHHHEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
SHWNCKGNFFCYLHDHNENTIVDPAVIYFDFVNPLRQGATQ
CCCCCCCCEEEEEEECCCCCEECHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TIQFETATTDVAAQCFLNALMRETRDWQIVPAASHQQYPQLHIPLSPSQAIRIALRHTS
EEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCCCCEEEEEEECCC
PTQHHQYLFPAYLYQQDDGAGVALSVEQLISLLLEKPAVKGELSDDVVARFRQRVLESHE
CCCCCCEECHHHEEECCCCCCEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
NTQQAINIRLDWPALRDKPLNFAQAEQGLLVGHAFHPAPKSHEPFNHQQAHRYLPDFAAS
CCCCEEEEEEECCCCCCCCCCHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHCHHHHHH
FPLRWFAVDKRQLCGDSLNLTLQQRLQRFAAESAPQLLAHFSDNVWLLPMHPWQADHLLT
CCEEEEEECHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
QNWCQDLVTQGLLQDLGEAGERWLPTSSSRSLYSASNRDMIKFSLSVRLTNSVRTLSVKE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEHHH
VKRGIRLARLAQTPRWQQLQARYPTFRVMQEDGWAGLRSADGTVQEESLMALRDNLLFDQ
HHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
PQSQTNVLVTLTQAAPDGGDSLLAAAVRRLASRLNLPLQQAAHTWLDAYCQQVLLPLFST
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
EADYGLVLLAHQQNILVEMQQDLPIGMLYRDCQGSGFTRDAGPWLEEIGEADAENRFSEQ
CCCCCEEEEEECCCEEHEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHCCCCHHHHCCHH
QLLRYFPYYLLVNSSLAVTAALAAAGFDSEEALMARVRDALSGLRANAKNTLCLDYVLDS
HHHHHCCHHHEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
SHWNCKGNFFCYLHDHNENTIVDPAVIYFDFVNPLRQGATQ
CCCCCCCCEEEEEEECCCCCEECHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; citrate; N6-acetyl-N6-hydroxylysine

Specific reaction: 4 ATP + citrate + N6-acetyl-N6-hydroxylysine = 4 ADP + 4 phosphate + aerobactin

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8003107 [H]