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The map label for this gene is gmuD [H]

Identifier: 157369081

GI number: 157369081

Start: 931630

End: 933015

Strand: Direct

Name: gmuD [H]

Synonym: Spro_0836

Alternate gene names: 157369081

Gene position: 931630-933015 (Clockwise)

Preceding gene: 157369080

Following gene: 157369082

Centisome position: 17.1

GC content: 52.45

Gene sequence:

>1386_bases
ATGAAATATCAATTTGCTGACGATTTCTGGTGGGGAAGCGCCACCTCGGCACCCCAGTCGGAAGGGGCTGCCGCACGGGA
TGGCAAAAGCCAGAACATCTTCGACTACTGGTATGAGATTGCACCAGAACGTTTTCATCATCAGGTCGGCCCGTCCGAGA
CCTCCACGTTTTATGACAACTTCCAGCAAGATATCCTGCTGTTAAAAAACCTTGGGCATAATAGCTTCAGAACCTCTATC
TCCTGGTCGCGGTTGATCCCGGATGGGGATGGCGAAGTGAATCCGAAAGCGGTGGCTTTCTATAATGCGCTGATCGACAG
CCTACTGGCTCAGGGCATCACGCCATTTATCAATCTTTACCATTTCGATATGCCGCTGTGCATGCAGCAACAAGGTGGCT
GGGAAAGCCGGACGGTGGTTGATGCCTACGCGCGTTATGCCAAAACCTGTTTCAGCCTGTTCGGCGACAGAGTCAGCCAT
TGGTTCACCTTTAATGAGCCGATTGTCCCGGTCGAAGCCGGGTATCTGAACGACCTGCATTATCCTTGTGTCATTGATTT
CAAAAGGGCAATTACAGTGGCTTACCACAGCGTGTTGGCCCATGCCAAAGCGGTGAGCGAGTTCAGGGCGCTGGGGAACC
AGGGTTCTATCGGCATTATTTTGAACCTGAGTCCGACCTATCCTCGTTCGGACAGCCAGGAAGATGGCGTGGCGGCTCAC
TATGCGGATCTGTTGCTGAATAAAAGCTTCCTCGATCCGGTGACCAAAGGGCGTTATCCGGACGATTTGGTGAATTTACT
GCGGGCCAATGATTTGTTGCCGCAGACAGCAGCGGAAGACGCGCAGCTGATTGCCGATGGGGTGGTGGATATTCTGGGCG
TCAATTACTACCAACCGCGCAGGGTCAAAGCAAAAGAAGGTTATCAGGCCAGCGACCCGGTAACCATGCCGGAAGACCTG
TTCAGCTATTACGCCATGCCGGGCCGCAAGATTAACCCGCACCGCGGCTGGGAAATCTATGAAAAAGGCCTGTATGACAT
CCTGATGGATCTGAAGGAAAACTACGGCAACATTCCCTGCTATATTTCAGAAAACGGTATGGGTGTGGAGGGCGAAGAGG
CCTTCATCGGTGCCAGTGGGCGGGTAGAGGACGATTATCGAATCGACTTTATTCGTGACCATCTGAAATGGTTGCATCAG
GCGTTGTCCGAGGGCTCCAACTGTAAGGGCTACCATCTATGGACCTTTATTGACTGCTGGTCCTGGCTCAATGCCTACAA
GAATCGCTACGGGTTAGTCCGGCTGGAGCGGGATAGCCAGCAACGTACGATTAAAAAGAGCGGCTATTGGTTTGCCGAGA
CGGCCAGGCAAAACGGTTTTGATTAA

Upstream 100 bases:

>100_bases
TGATCAGGCAACGGAAAGCGAAGAAGACATCGCCAAAGCGTTGAAATTCTAACTGCAGTCTGGGGCAGCGCTTGCTGCCC
CGGTTTTAGAGGGGCTTCTG

Downstream 100 bases:

>100_bases
TGGGAGCGCGCGCGGTGTCTGACAACCTGGTTTCGCTGAATACCAACGACGTTAAGCTGATTCGGGAGCAGGATTTTTTT
AACTGCAAAGATTTCCATCT

Product: beta-glucosidase

Products: NA

Alternate protein names: Aryl-phospho-beta-D-glucosidase BglD; Glucomannan utilization protein D [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MKYQFADDFWWGSATSAPQSEGAAARDGKSQNIFDYWYEIAPERFHHQVGPSETSTFYDNFQQDILLLKNLGHNSFRTSI
SWSRLIPDGDGEVNPKAVAFYNALIDSLLAQGITPFINLYHFDMPLCMQQQGGWESRTVVDAYARYAKTCFSLFGDRVSH
WFTFNEPIVPVEAGYLNDLHYPCVIDFKRAITVAYHSVLAHAKAVSEFRALGNQGSIGIILNLSPTYPRSDSQEDGVAAH
YADLLLNKSFLDPVTKGRYPDDLVNLLRANDLLPQTAAEDAQLIADGVVDILGVNYYQPRRVKAKEGYQASDPVTMPEDL
FSYYAMPGRKINPHRGWEIYEKGLYDILMDLKENYGNIPCYISENGMGVEGEEAFIGASGRVEDDYRIDFIRDHLKWLHQ
ALSEGSNCKGYHLWTFIDCWSWLNAYKNRYGLVRLERDSQQRTIKKSGYWFAETARQNGFD

Sequences:

>Translated_461_residues
MKYQFADDFWWGSATSAPQSEGAAARDGKSQNIFDYWYEIAPERFHHQVGPSETSTFYDNFQQDILLLKNLGHNSFRTSI
SWSRLIPDGDGEVNPKAVAFYNALIDSLLAQGITPFINLYHFDMPLCMQQQGGWESRTVVDAYARYAKTCFSLFGDRVSH
WFTFNEPIVPVEAGYLNDLHYPCVIDFKRAITVAYHSVLAHAKAVSEFRALGNQGSIGIILNLSPTYPRSDSQEDGVAAH
YADLLLNKSFLDPVTKGRYPDDLVNLLRANDLLPQTAAEDAQLIADGVVDILGVNYYQPRRVKAKEGYQASDPVTMPEDL
FSYYAMPGRKINPHRGWEIYEKGLYDILMDLKENYGNIPCYISENGMGVEGEEAFIGASGRVEDDYRIDFIRDHLKWLHQ
ALSEGSNCKGYHLWTFIDCWSWLNAYKNRYGLVRLERDSQQRTIKKSGYWFAETARQNGFD
>Mature_461_residues
MKYQFADDFWWGSATSAPQSEGAAARDGKSQNIFDYWYEIAPERFHHQVGPSETSTFYDNFQQDILLLKNLGHNSFRTSI
SWSRLIPDGDGEVNPKAVAFYNALIDSLLAQGITPFINLYHFDMPLCMQQQGGWESRTVVDAYARYAKTCFSLFGDRVSH
WFTFNEPIVPVEAGYLNDLHYPCVIDFKRAITVAYHSVLAHAKAVSEFRALGNQGSIGIILNLSPTYPRSDSQEDGVAAH
YADLLLNKSFLDPVTKGRYPDDLVNLLRANDLLPQTAAEDAQLIADGVVDILGVNYYQPRRVKAKEGYQASDPVTMPEDL
FSYYAMPGRKINPHRGWEIYEKGLYDILMDLKENYGNIPCYISENGMGVEGEEAFIGASGRVEDDYRIDFIRDHLKWLHQ
ALSEGSNCKGYHLWTFIDCWSWLNAYKNRYGLVRLERDSQQRTIKKSGYWFAETARQNGFD

Specific function: Phospho-beta-D-glucosidase that seems to be involved in the degradation of glucomannan. Is also capable of hydrolyzing aryl-phospho-beta-D-glucosides, although very weakly, and plays only a minor role, if any, in the degradation of these substrates in viv

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI13273313, Length=481, Percent_Identity=29.1060291060291, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI32481206, Length=487, Percent_Identity=31.6221765913758, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI110681710, Length=480, Percent_Identity=29.1666666666667, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI28376633, Length=469, Percent_Identity=27.9317697228145, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI24497614, Length=484, Percent_Identity=26.0330578512397, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI2367174, Length=490, Percent_Identity=30.6122448979592, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1789070, Length=489, Percent_Identity=30.879345603272, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI2367270, Length=474, Percent_Identity=29.3248945147679, Blast_Score=187, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI17552856, Length=480, Percent_Identity=31.0416666666667, Blast_Score=201, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17539390, Length=481, Percent_Identity=31.1850311850312, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI21356577, Length=483, Percent_Identity=28.7784679089027, Blast_Score=191, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 52570; Mature: 52570

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQFADDFWWGSATSAPQSEGAAARDGKSQNIFDYWYEIAPERFHHQVGPSETSTFYDN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHCCCCCHHHHHHHH
FQQDILLLKNLGHNSFRTSISWSRLIPDGDGEVNPKAVAFYNALIDSLLAQGITPFINLY
HHHHHHHHHHCCCCHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
HFDMPLCMQQQGGWESRTVVDAYARYAKTCFSLFGDRVSHWFTFNEPIVPVEAGYLNDLH
HCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCCCCCCCC
YPCVIDFKRAITVAYHSVLAHAKAVSEFRALGNQGSIGIILNLSPTYPRSDSQEDGVAAH
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHH
YADLLLNKSFLDPVTKGRYPDDLVNLLRANDLLPQTAAEDAQLIADGVVDILGVNYYQPR
HHHHHHHHHHHCHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
RVKAKEGYQASDPVTMPEDLFSYYAMPGRKINPHRGWEIYEKGLYDILMDLKENYGNIPC
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCE
YISENGMGVEGEEAFIGASGRVEDDYRIDFIRDHLKWLHQALSEGSNCKGYHLWTFIDCW
EECCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHH
SWLNAYKNRYGLVRLERDSQQRTIKKSGYWFAETARQNGFD
HHHHHHHCCCCEEEECCCCHHHHHHHCCCEEEEHHHCCCCC
>Mature Secondary Structure
MKYQFADDFWWGSATSAPQSEGAAARDGKSQNIFDYWYEIAPERFHHQVGPSETSTFYDN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHCCCCCHHHHHHHH
FQQDILLLKNLGHNSFRTSISWSRLIPDGDGEVNPKAVAFYNALIDSLLAQGITPFINLY
HHHHHHHHHHCCCCHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
HFDMPLCMQQQGGWESRTVVDAYARYAKTCFSLFGDRVSHWFTFNEPIVPVEAGYLNDLH
HCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCCCCCCCC
YPCVIDFKRAITVAYHSVLAHAKAVSEFRALGNQGSIGIILNLSPTYPRSDSQEDGVAAH
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHH
YADLLLNKSFLDPVTKGRYPDDLVNLLRANDLLPQTAAEDAQLIADGVVDILGVNYYQPR
HHHHHHHHHHHCHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
RVKAKEGYQASDPVTMPEDLFSYYAMPGRKINPHRGWEIYEKGLYDILMDLKENYGNIPC
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCE
YISENGMGVEGEEAFIGASGRVEDDYRIDFIRDHLKWLHQALSEGSNCKGYHLWTFIDCW
EECCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHH
SWLNAYKNRYGLVRLERDSQQRTIKKSGYWFAETARQNGFD
HHHHHHHCCCCEEEECCCCHHHHHHHCCCEEEEHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]