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The map label for this gene is surE

Identifier: 157369074

GI number: 157369074

Start: 922695

End: 923456

Strand: Direct

Name: surE

Synonym: Spro_0829

Alternate gene names: 157369074

Gene position: 922695-923456 (Clockwise)

Preceding gene: 157369073

Following gene: 157369075

Centisome position: 16.93

GC content: 58.14

Gene sequence:

>762_bases
ATGCGGATATTGCTGAGTAATGACGACGGCGTGACCGCCCCGGGCATCCAGGTGCTGGCGGCGGCATTGAGAGAGTTCGC
CGAAGTGCAAGTTGTGGCACCCGATCGTAACCGCAGTGGTTCTTCCAATGCGCTGACGCTGGAATCTCCATTGCGCACCC
TGACGATGCCCAATGGAGATATCGCCGTACAGCAGGGAACGCCGACAGACTGCGTGTACCTGGGAGTGAATGCCCTGATG
CAGCCTGCGCCGGATATTGTGGTTTCCGGCATCAATGCGGGCCCCAATCTGGGCGATGACGTTATCTATTCCGGCACCGT
AGCGGCTGCTATGGAAGGGCGTCATTTGGGATTGCCTGCGCTGGCCGTGTCGTTGAACGGCCATCAGCATTATGCGACCG
CCGCGGCGATCACCTGCCGGGTGCTGCGTGCGTTACAGCGCGAACCGTTGCGCACCGGTAAAATTCTGAATATCAACGTG
CCGGATTTGCCGCTGGACCAGATTAAGGGCATTCGTGTGACCCGCTGCGGTAGTCGCCATCCGGCTGACAAAGTGTTCTG
CCAACAAGATCCGCGTGGGCAAAATCTCTATTGGATTGGGCCGCCTGGTGATAAGTTTGATGCCGGGCCGGACACGGATT
TCGCTGCGGTAGAACAGGGTTATGTGGCCATCACGCCACTGCAGGTGGATTTAACCGCTTATGCAGCCCAGGACGTGGTA
AAAACGTGGTTAACCAAAGCAGGGGTTGGCGGGGAATGGTGA

Upstream 100 bases:

>100_bases
CTGGTTAAGTCCCTCCTTTTGGGCGTTGATTTCGAGTATTTAAATACCAGGCCGCGTTAAAGGCGTTCTGATTGAGAGAT
AAAAAAGAAGACAATCTTTT

Downstream 100 bases:

>100_bases
ACAAGCGTATGCAAACATTGCTGACGCAGCTGCGTCAACAGGGGATCCGGGACGAACGGTTGCTACAGGCGATCGAAGCA
GTGCCGCGTGAACGCTTTGT

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: 5'/3'-nucleotidase; Nucleoside monophosphate phosphohydrolase; Exopolyphosphatase

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MRILLSNDDGVTAPGIQVLAAALREFAEVQVVAPDRNRSGSSNALTLESPLRTLTMPNGDIAVQQGTPTDCVYLGVNALM
QPAPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGLPALAVSLNGHQHYATAAAITCRVLRALQREPLRTGKILNINV
PDLPLDQIKGIRVTRCGSRHPADKVFCQQDPRGQNLYWIGPPGDKFDAGPDTDFAAVEQGYVAITPLQVDLTAYAAQDVV
KTWLTKAGVGGEW

Sequences:

>Translated_253_residues
MRILLSNDDGVTAPGIQVLAAALREFAEVQVVAPDRNRSGSSNALTLESPLRTLTMPNGDIAVQQGTPTDCVYLGVNALM
QPAPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGLPALAVSLNGHQHYATAAAITCRVLRALQREPLRTGKILNINV
PDLPLDQIKGIRVTRCGSRHPADKVFCQQDPRGQNLYWIGPPGDKFDAGPDTDFAAVEQGYVAITPLQVDLTAYAAQDVV
KTWLTKAGVGGEW
>Mature_253_residues
MRILLSNDDGVTAPGIQVLAAALREFAEVQVVAPDRNRSGSSNALTLESPLRTLTMPNGDIAVQQGTPTDCVYLGVNALM
QPAPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGLPALAVSLNGHQHYATAAAITCRVLRALQREPLRTGKILNINV
PDLPLDQIKGIRVTRCGSRHPADKVFCQQDPRGQNLYWIGPPGDKFDAGPDTDFAAVEQGYVAITPLQVDLTAYAAQDVV
KTWLTKAGVGGEW

Specific function: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'- monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase acti

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=253, Percent_Identity=82.2134387351779, Blast_Score=429, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_SERP5 (A8G9Z5)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477063.1
- ProteinModelPortal:   A8G9Z5
- SMR:   A8G9Z5
- STRING:   A8G9Z5
- GeneID:   5603034
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0829
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   DCVKMGI
- ProtClustDB:   PRK00346
- BioCyc:   SPRO399741:SPRO_0829-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5; =3.1.3.6; =3.6.1.11

Molecular weight: Translated: 26842; Mature: 26842

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLSNDDGVTAPGIQVLAAALREFAEVQVVAPDRNRSGSSNALTLESPLRTLTMPNGD
CEEEEECCCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEECCCCEEEECCCCC
IAVQQGTPTDCVYLGVNALMQPAPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGLPA
EEEECCCCCCEEEECHHHHHCCCCCEEEECCCCCCCCCCCEEECCEEEEEECCCCCCCCE
LAVSLNGHQHYATAAAITCRVLRALQREPLRTGKILNINVPDLPLDQIKGIRVTRCGSRH
EEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHCCEEEEECCCCC
PADKVFCQQDPRGQNLYWIGPPGDKFDAGPDTDFAAVEQGYVAITPLQVDLTAYAAQDVV
CCCCCEECCCCCCCEEEEECCCCCCCCCCCCCCHHHHHCCEEEEEEEEEEHHHHHHHHHH
KTWLTKAGVGGEW
HHHHHHCCCCCCC
>Mature Secondary Structure
MRILLSNDDGVTAPGIQVLAAALREFAEVQVVAPDRNRSGSSNALTLESPLRTLTMPNGD
CEEEEECCCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEECCCCEEEECCCCC
IAVQQGTPTDCVYLGVNALMQPAPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGLPA
EEEECCCCCCEEEECHHHHHCCCCCEEEECCCCCCCCCCCEEECCEEEEEECCCCCCCCE
LAVSLNGHQHYATAAAITCRVLRALQREPLRTGKILNINVPDLPLDQIKGIRVTRCGSRH
EEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHCCEEEEECCCCC
PADKVFCQQDPRGQNLYWIGPPGDKFDAGPDTDFAAVEQGYVAITPLQVDLTAYAAQDVV
CCCCCEECCCCCCCEEEEECCCCCCCCCCCCCCHHHHHCCEEEEEEEEEEHHHHHHHHHH
KTWLTKAGVGGEW
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA