Click here to switch to the map view.

The map label for this gene is yccK [H]

Identifier: 157368893

GI number: 157368893

Start: 713333

End: 714325

Strand: Direct

Name: yccK [H]

Synonym: Spro_0648

Alternate gene names: 157368893

Gene position: 713333-714325 (Clockwise)

Preceding gene: 157368891

Following gene: 157368895

Centisome position: 13.09

GC content: 59.42

Gene sequence:

>993_bases
ATGCAACAACGTCAATTAGGTCCCAATGGCCCGACCGTTTCCGCCCTGGGGCTGGGCTGCATGGGGATGAGTGATTTCTA
TTCGACGGCGCAGGACGAAAAAGAGGCCATCGCCACACTGCACCGGGCATTGGAACTGGGGGTCACCCTGCTCGATACCG
CCGACATGTACGGCCCGCACACCAACGAACGGTTGATTGGTAAAGCGATCAAGGGCAAACGGCAGCAGGTCTTCCTGGCC
ACCAAATTTGGCATCCTGCGCGATCCGGCCGATCCCGGCGCCCGGGGCGTCAGCAGTCGGCCGGAGTATATCCGTCGTTC
GGTAGAAGGCAGCCTGCAGCGGCTTGGGGTTGAGGTGATAGATCTTTATTACCAGCATCGCGTGGATCCAGAAGTGCCTA
TCGAAGAGGTGGTTGGCACCATGGCGGACCTGATCAGCGAAGGTAAAATCCGCTACATCGGGTTGAGCGAGGCTTCGGTC
GCTACGCTGGAGCGTGCGCACAAGGTGCATCCGATAACCGCGTTGCAGACCGAGTATTCACTGTGGACGCGTGATGCCGA
GCAAGGGGTATTGGCGGCCTGTGAGCATCTGGGCATCGGCTTTGTTCCTTACAGCCCGTTAGGGAGAGGTTTTCTGACCG
GAGCTATCCAACGGCCGGAAGATCTGGATGCCGACGACTTCCGCCGCAGCAACCCGCGTTTCCAGGGGGAAAACTTTGCC
CGCAATCTGGCGCTGGTGGAGAAAGTGAGCGAATTGGCCAAACAGAAAGGCGTAGCACCTTCACAGCTGGCATTGGCGTG
GGTATTGGCGCAGGGCGAGCATATTGTGCCGATCCCGGGGACCAAGCGCCGTCGTTATCTGGAAGAGAACATTGCGGCGG
TCGAACTGACGCTGAGCCAGGCGGAACTGGCGGCGATTGAGGCGGTGTTTCCGTTGCAGGCGGCGGCAGGCGCACGCTAT
GGCGCAGAGTCGATGACCTATATCAACGGATAA

Upstream 100 bases:

>100_bases
AACAGTGATGTGTAATCTGCATTATTTATCTTTACAGGGTAAACAACCAGACTCTGTTGTACCAGCACTCCGCTGATGAA
AACCGCATGAGGGCAACACA

Downstream 100 bases:

>100_bases
AAAAAGGGCGCGGCGTGTGAACGCTGCGCCCTGATCCCCGCTATTTGCGGGCGGCGTTACTTATTTCTTCTTCTTGGCAT
CGCGTGGTGCACGGGCAACG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MQQRQLGPNGPTVSALGLGCMGMSDFYSTAQDEKEAIATLHRALELGVTLLDTADMYGPHTNERLIGKAIKGKRQQVFLA
TKFGILRDPADPGARGVSSRPEYIRRSVEGSLQRLGVEVIDLYYQHRVDPEVPIEEVVGTMADLISEGKIRYIGLSEASV
ATLERAHKVHPITALQTEYSLWTRDAEQGVLAACEHLGIGFVPYSPLGRGFLTGAIQRPEDLDADDFRRSNPRFQGENFA
RNLALVEKVSELAKQKGVAPSQLALAWVLAQGEHIVPIPGTKRRRYLEENIAAVELTLSQAELAAIEAVFPLQAAAGARY
GAESMTYING

Sequences:

>Translated_330_residues
MQQRQLGPNGPTVSALGLGCMGMSDFYSTAQDEKEAIATLHRALELGVTLLDTADMYGPHTNERLIGKAIKGKRQQVFLA
TKFGILRDPADPGARGVSSRPEYIRRSVEGSLQRLGVEVIDLYYQHRVDPEVPIEEVVGTMADLISEGKIRYIGLSEASV
ATLERAHKVHPITALQTEYSLWTRDAEQGVLAACEHLGIGFVPYSPLGRGFLTGAIQRPEDLDADDFRRSNPRFQGENFA
RNLALVEKVSELAKQKGVAPSQLALAWVLAQGEHIVPIPGTKRRRYLEENIAAVELTLSQAELAAIEAVFPLQAAAGARY
GAESMTYING
>Mature_330_residues
MQQRQLGPNGPTVSALGLGCMGMSDFYSTAQDEKEAIATLHRALELGVTLLDTADMYGPHTNERLIGKAIKGKRQQVFLA
TKFGILRDPADPGARGVSSRPEYIRRSVEGSLQRLGVEVIDLYYQHRVDPEVPIEEVVGTMADLISEGKIRYIGLSEASV
ATLERAHKVHPITALQTEYSLWTRDAEQGVLAACEHLGIGFVPYSPLGRGFLTGAIQRPEDLDADDFRRSNPRFQGENFA
RNLALVEKVSELAKQKGVAPSQLALAWVLAQGEHIVPIPGTKRRRYLEENIAAVELTLSQAELAAIEAVFPLQAAAGARY
GAESMTYING

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436971, Length=283, Percent_Identity=31.4487632508834, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI27436964, Length=311, Percent_Identity=30.2250803858521, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI27436966, Length=311, Percent_Identity=30.2250803858521, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI27436962, Length=311, Percent_Identity=30.2250803858521, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI27436969, Length=327, Percent_Identity=28.7461773700306, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI4504825, Length=324, Percent_Identity=28.7037037037037, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI223718702, Length=293, Percent_Identity=31.3993174061433, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI41327764, Length=281, Percent_Identity=33.0960854092527, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI41152114, Length=225, Percent_Identity=30.2222222222222, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87081735, Length=333, Percent_Identity=30.6306306306306, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788070, Length=315, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1789375, Length=327, Percent_Identity=30.5810397553517, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1787674, Length=307, Percent_Identity=28.9902280130293, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788081, Length=321, Percent_Identity=27.7258566978193, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789199, Length=350, Percent_Identity=29.1428571428571, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI48994888, Length=178, Percent_Identity=28.6516853932584, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17564128, Length=306, Percent_Identity=23.202614379085, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=345, Percent_Identity=28.1159420289855, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6325384, Length=318, Percent_Identity=28.9308176100629, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323998, Length=325, Percent_Identity=25.2307692307692, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319958, Length=297, Percent_Identity=23.2323232323232, Blast_Score=102, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6322615, Length=252, Percent_Identity=24.6031746031746, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319951, Length=308, Percent_Identity=24.025974025974, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320079, Length=309, Percent_Identity=23.9482200647249, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646155, Length=313, Percent_Identity=26.517571884984, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646159, Length=303, Percent_Identity=25.0825082508251, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI45553081, Length=327, Percent_Identity=26.605504587156, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640980, Length=342, Percent_Identity=23.9766081871345, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45549126, Length=342, Percent_Identity=23.9766081871345, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644950, Length=336, Percent_Identity=25.297619047619, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36036; Mature: 36036

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQRQLGPNGPTVSALGLGCMGMSDFYSTAQDEKEAIATLHRALELGVTLLDTADMYGPH
CCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
TNERLIGKAIKGKRQQVFLATKFGILRDPADPGARGVSSRPEYIRRSVEGSLQRLGVEVI
CCHHHHHHHHCCCCCEEEEEECCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLYYQHRVDPEVPIEEVVGTMADLISEGKIRYIGLSEASVATLERAHKVHPITALQTEYS
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHH
LWTRDAEQGVLAACEHLGIGFVPYSPLGRGFLTGAIQRPEDLDADDFRRSNPRFQGENFA
HHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHCCCCCCCCHHHH
RNLALVEKVSELAKQKGVAPSQLALAWVLAQGEHIVPIPGTKRRRYLEENIAAVELTLSQ
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHCCEEEEEEHHH
AELAAIEAVFPLQAAAGARYGAESMTYING
HHHHHHHHHHHHHHHHCCCCCCCCCCEECC
>Mature Secondary Structure
MQQRQLGPNGPTVSALGLGCMGMSDFYSTAQDEKEAIATLHRALELGVTLLDTADMYGPH
CCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
TNERLIGKAIKGKRQQVFLATKFGILRDPADPGARGVSSRPEYIRRSVEGSLQRLGVEVI
CCHHHHHHHHCCCCCEEEEEECCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLYYQHRVDPEVPIEEVVGTMADLISEGKIRYIGLSEASVATLERAHKVHPITALQTEYS
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHH
LWTRDAEQGVLAACEHLGIGFVPYSPLGRGFLTGAIQRPEDLDADDFRRSNPRFQGENFA
HHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHCCCCCCCCHHHH
RNLALVEKVSELAKQKGVAPSQLALAWVLAQGEHIVPIPGTKRRRYLEENIAAVELTLSQ
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHCCEEEEEEHHH
AELAAIEAVFPLQAAAGARYGAESMTYING
HHHHHHHHHHHHHHHHCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]