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The map label for this gene is hipA [H]

Identifier: 157368813

GI number: 157368813

Start: 630242

End: 630592

Strand: Direct

Name: hipA [H]

Synonym: Spro_0568

Alternate gene names: 157368813

Gene position: 630242-630592 (Clockwise)

Preceding gene: 157368812

Following gene: 157368822

Centisome position: 11.57

GC content: 55.84

Gene sequence:

>351_bases
ATGGAAAAGTTACGCGTGGCGCTGAATGGCACTGTTGTTGGGACGCTGGAAAAGCATGCCGGCGGCGCGATGTCGTTTGT
TTACCAGGAAGAGTGGCTGGCACAAGCCGGCGCACGCGCCATATCGTTATCCCTGCCGTTACAGCCAGAGCCGTTCCGCG
GCGACATGGTGTATAACTTTTTCGACAACCTGCTGCCGGACAGCGAACTCATTCGCAGCCGCATACAGGCGCGCTTCAGA
ACGACAACCAAACAACCTTTTGATCTGCTGGCCAGCATTGGCAGCGACTGTGTGGGGGCGATCCAGCTTTACCCTGAACA
TGCTGAAGAAGTCCCGGTGAAGCTTAAATGA

Upstream 100 bases:

>100_bases
AGACGTTGTTTAAACTGCTTGCTGCGCTGGACCTGGAGCTACAGGTCACCCCGCGTGGTAAGCCGGTAGATCCCAAGACC
TGGGATCAGGAGTGGTAAGC

Downstream 100 bases:

>100_bases
AATTTCTGATGAAAAGTTAATGTAAACATCAGAAATTTCAATGATAATTTATGCTGGGGTTATGAAATTATCAAAATTTA
TATCGGGTTGACCTTGGCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MEKLRVALNGTVVGTLEKHAGGAMSFVYQEEWLAQAGARAISLSLPLQPEPFRGDMVYNFFDNLLPDSELIRSRIQARFR
TTTKQPFDLLASIGSDCVGAIQLYPEHAEEVPVKLK

Sequences:

>Translated_116_residues
MEKLRVALNGTVVGTLEKHAGGAMSFVYQEEWLAQAGARAISLSLPLQPEPFRGDMVYNFFDNLLPDSELIRSRIQARFR
TTTKQPFDLLASIGSDCVGAIQLYPEHAEEVPVKLK
>Mature_116_residues
MEKLRVALNGTVVGTLEKHAGGAMSFVYQEEWLAQAGARAISLSLPLQPEPFRGDMVYNFFDNLLPDSELIRSRIQARFR
TTTKQPFDLLASIGSDCVGAIQLYPEHAEEVPVKLK

Specific function: Unbalanced or excessive expression of hipA is toxic to the cell [H]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0665 [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=106, Percent_Identity=53.7735849056604, Blast_Score=114, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 12907; Mature: 12907

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLRVALNGTVVGTLEKHAGGAMSFVYQEEWLAQAGARAISLSLPLQPEPFRGDMVYNF
CCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHH
FDNLLPDSELIRSRIQARFRTTTKQPFDLLASIGSDCVGAIQLYPEHAEEVPVKLK
HHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MEKLRVALNGTVVGTLEKHAGGAMSFVYQEEWLAQAGARAISLSLPLQPEPFRGDMVYNF
CCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHH
FDNLLPDSELIRSRIQARFRTTTKQPFDLLASIGSDCVGAIQLYPEHAEEVPVKLK
HHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1715862; 9278503; 8021189 [H]