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The map label for this gene is ytfL [H]

Identifier: 157368704

GI number: 157368704

Start: 505347

End: 506690

Strand: Reverse

Name: ytfL [H]

Synonym: Spro_0457

Alternate gene names: 157368704

Gene position: 506690-505347 (Counterclockwise)

Preceding gene: 157368705

Following gene: 157368702

Centisome position: 9.3

GC content: 53.57

Gene sequence:

>1344_bases
ATGTTAAACAGTATTTTACTGATTCTTTTTCTGATCGCAGTGAGTGCGTTCTTCTCACTGTCGGAAATATCTCTGGCCGC
GTCACGCAAGATTAAACTGAAAATGATGGCTGACGAAGGTAACGTCAATGCCGCCAAAGTCCTCAAACTGCAAGAAACCC
CGGGGCTGTATTTTACCGTGGTACAGATTGGCCTGAACGCCGTGGCCATTCTCGGCGGTATCGTCGGCGATGCAGCCTTT
TCTCCTACATTCCAACCGTTGTTCGACCGCTTTTTATCACCTGAACTGGCAGAGCAGGCCAGCTTCGTCTGTTCGTTCGT
ACTGGTAACCAGCCTGTTTATCCTGTTTGCAGATTTGACCCCGAAGCGCATCGGTATGATTGCACCAGAGACGTTTGCCG
TCCGGATCATCAACCCGATGCGTTTCTCGATCATGATTTTCCGGCCGCTGGTGTGGTTCTTCAACGGCATGGCAAACCTG
ATCTTCCGCCTGTTCAAACTGCCGATGGTGCGCAAAGACGACATCACCTCCGACGATATCTACGCGGTGGTAGAAGCCGG
TGCCCTGGCGGGTGTGCTGCGCAAACAGGAACATGAGCTGATCGAAAACGTGTTCGAACTGGAGTCTCGCACCGTACCTT
CGTCGATGACCTCGCGTGAAAGCGTGGTTTACTTCGACCTGCGTGAGACCGAAGAAAGCATTATCGAGAAGGTCTCGACC
CATCCGCACTCCAAGTTCCTAGTCTGTGATGGCAATATCGATCAAGTCGTCGGCTACGTGGACTCCAAAGACCTGTTGAA
CCGCGTGCTGGGCAATCAGAGCCTGGTGCTGAGCAGCGGCGTGCAGATCCGCTCGGCGCTGATCGTGCCGGATACCCTGA
CGCTGTCCGAAGCGCTGGAAAGCTTTAAAACCGCCGGTGAAGACTTTGCGGTTATTCTCAATGAATATGCGTTGGTCGTG
GGTATCATCACACTCAATGACGTGATGACCACGCTGATGGGCGATCTGGTAGGCCAGGGCCAGGAAGAGCAGATCGTGGC
GCGTGATGAAAGCTCATGGCTGATTGAGGGCGGGACGCCGATCGACGATGTAATGCGCGTGCTGCACATTGATGAGTTCC
CGCAGGCGGGCAACTACGAAACCATCGGCGGCTTTATGATGTATATGCTGCGCAAGATCCCAAAACGGACCGACTTCGTC
AAATACGCCGGCTACAAGTTTGAAGTGGTGGATATCGACAGCTACAAGATTGACCAGCTGTTGGTAACCAGGCTGAGCGA
CAAACCGGCATCGGTACTGCCGAAGGCACCGGAAGAAAACCCCGCGCCTGATCTCCATCGATAA

Upstream 100 bases:

>100_bases
GGCCCGATAACCTTCTTTCTGGTTGTTATCGCTACTTTTTTTACAATGTACTACCCTTCCTCAAGAGCGCCGTCATCCCG
TCGGCACGTATGGATAGATT

Downstream 100 bases:

>100_bases
AAACGTCAGCGGCCCCAAACGGGGCCGCGATTATTTTAGCTTTTGCAGGTGCTCTAACTATTACCCTATGAATTTCGAGT
TGCAGCTAGGCGGCCAGCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MLNSILLILFLIAVSAFFSLSEISLAASRKIKLKMMADEGNVNAAKVLKLQETPGLYFTVVQIGLNAVAILGGIVGDAAF
SPTFQPLFDRFLSPELAEQASFVCSFVLVTSLFILFADLTPKRIGMIAPETFAVRIINPMRFSIMIFRPLVWFFNGMANL
IFRLFKLPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTSRESVVYFDLRETEESIIEKVST
HPHSKFLVCDGNIDQVVGYVDSKDLLNRVLGNQSLVLSSGVQIRSALIVPDTLTLSEALESFKTAGEDFAVILNEYALVV
GIITLNDVMTTLMGDLVGQGQEEQIVARDESSWLIEGGTPIDDVMRVLHIDEFPQAGNYETIGGFMMYMLRKIPKRTDFV
KYAGYKFEVVDIDSYKIDQLLVTRLSDKPASVLPKAPEENPAPDLHR

Sequences:

>Translated_447_residues
MLNSILLILFLIAVSAFFSLSEISLAASRKIKLKMMADEGNVNAAKVLKLQETPGLYFTVVQIGLNAVAILGGIVGDAAF
SPTFQPLFDRFLSPELAEQASFVCSFVLVTSLFILFADLTPKRIGMIAPETFAVRIINPMRFSIMIFRPLVWFFNGMANL
IFRLFKLPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTSRESVVYFDLRETEESIIEKVST
HPHSKFLVCDGNIDQVVGYVDSKDLLNRVLGNQSLVLSSGVQIRSALIVPDTLTLSEALESFKTAGEDFAVILNEYALVV
GIITLNDVMTTLMGDLVGQGQEEQIVARDESSWLIEGGTPIDDVMRVLHIDEFPQAGNYETIGGFMMYMLRKIPKRTDFV
KYAGYKFEVVDIDSYKIDQLLVTRLSDKPASVLPKAPEENPAPDLHR
>Mature_447_residues
MLNSILLILFLIAVSAFFSLSEISLAASRKIKLKMMADEGNVNAAKVLKLQETPGLYFTVVQIGLNAVAILGGIVGDAAF
SPTFQPLFDRFLSPELAEQASFVCSFVLVTSLFILFADLTPKRIGMIAPETFAVRIINPMRFSIMIFRPLVWFFNGMANL
IFRLFKLPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTSRESVVYFDLRETEESIIEKVST
HPHSKFLVCDGNIDQVVGYVDSKDLLNRVLGNQSLVLSSGVQIRSALIVPDTLTLSEALESFKTAGEDFAVILNEYALVV
GIITLNDVMTTLMGDLVGQGQEEQIVARDESSWLIEGGTPIDDVMRVLHIDEFPQAGNYETIGGFMMYMLRKIPKRTDFV
KYAGYKFEVVDIDSYKIDQLLVTRLSDKPASVLPKAPEENPAPDLHR

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=380, Percent_Identity=24.4736842105263, Blast_Score=151, Evalue=1e-36,
Organism=Escherichia coli, GI1790664, Length=438, Percent_Identity=81.0502283105023, Blast_Score=741, Evalue=0.0,
Organism=Escherichia coli, GI87082033, Length=238, Percent_Identity=33.1932773109244, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI145693175, Length=418, Percent_Identity=22.0095693779904, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788119, Length=246, Percent_Identity=26.4227642276423, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1786879, Length=275, Percent_Identity=21.8181818181818, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49697; Mature: 49697

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSILLILFLIAVSAFFSLSEISLAASRKIKLKMMADEGNVNAAKVLKLQETPGLYFTV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHEEEEECCCCEEEEH
VQIGLNAVAILGGIVGDAAFSPTFQPLFDRFLSPELAEQASFVCSFVLVTSLFILFADLT
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PKRIGMIAPETFAVRIINPMRFSIMIFRPLVWFFNGMANLIFRLFKLPMVRKDDITSDDI
HHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
YAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTSRESVVYFDLRETEESIIEKVST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHC
HPHSKFLVCDGNIDQVVGYVDSKDLLNRVLGNQSLVLSSGVQIRSALIVPDTLTLSEALE
CCCCEEEEECCCHHHHHHCCCCHHHHHHHHCCCCEEEECCCEEEEEEECCCCHHHHHHHH
SFKTAGEDFAVILNEYALVVGIITLNDVMTTLMGDLVGQGQEEQIVARDESSWLIEGGTP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCC
IDDVMRVLHIDEFPQAGNYETIGGFMMYMLRKIPKRTDFVKYAGYKFEVVDIDSYKIDQL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHEECCEEEEEEECCCHHHHHH
LVTRLSDKPASVLPKAPEENPAPDLHR
HHHHHCCCCHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLNSILLILFLIAVSAFFSLSEISLAASRKIKLKMMADEGNVNAAKVLKLQETPGLYFTV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHEEEEECCCCEEEEH
VQIGLNAVAILGGIVGDAAFSPTFQPLFDRFLSPELAEQASFVCSFVLVTSLFILFADLT
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PKRIGMIAPETFAVRIINPMRFSIMIFRPLVWFFNGMANLIFRLFKLPMVRKDDITSDDI
HHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
YAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTSRESVVYFDLRETEESIIEKVST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHC
HPHSKFLVCDGNIDQVVGYVDSKDLLNRVLGNQSLVLSSGVQIRSALIVPDTLTLSEALE
CCCCEEEEECCCHHHHHHCCCCHHHHHHHHCCCCEEEECCCEEEEEEECCCCHHHHHHHH
SFKTAGEDFAVILNEYALVVGIITLNDVMTTLMGDLVGQGQEEQIVARDESSWLIEGGTP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCC
IDDVMRVLHIDEFPQAGNYETIGGFMMYMLRKIPKRTDFVKYAGYKFEVVDIDSYKIDQL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHEECCEEEEEEECCCHHHHHH
LVTRLSDKPASVLPKAPEENPAPDLHR
HHHHHCCCCHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]