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The map label for this gene is xerC [H]

Identifier: 157368433

GI number: 157368433

Start: 207437

End: 208348

Strand: Direct

Name: xerC [H]

Synonym: Spro_0184

Alternate gene names: 157368433

Gene position: 207437-208348 (Clockwise)

Preceding gene: 157368432

Following gene: 157368434

Centisome position: 3.81

GC content: 60.2

Gene sequence:

>912_bases
ATGATCCCGCTGGCGGCCAGCCTGCAACAGCCGGTGGACGCTTTTTTGCGCTATCTGAAGGTCGAGCGCCAGCTCAGCCC
GCTCACCCAACTGAGTTATTCGCGTCAACTGCAGGCGCTGATGGCGCTGGCGCAGGAAATTGGCGTCACGGAGTGGCCGT
TGCTGGACGCCGCCAAAGTCCGTCAGCTTGCGGCGCGCAGTAAACGTGCCGGATTACAGTCTTCCAGCCTCGCGCTGCGC
CTGTCGGCGTTGCGCAGTTTTCTCGACTGGCAGGTCAGCCAGGGTATGCTGATTGCCAACCCGGCCAAAGGGATCCGAAC
GCCACGCAGCGGCCGTCATCTGCCGAAAAACATAGACGTTGATGAAATGAATCAGCTGCTGAATATCGATCTTAACGATC
CTTTGGCGGTGCGCGATCGCGCCATGCTTGAAGTCATGTACGGTGCCGGGCTGCGTCTTTCGGAACTGGTGGGGCTGGAC
TGTCGCCATGTCGATCTGGCCGCCGGTGAAATCTGGGTGTTGGGTAAGGGCAGCAAGGAACGCAAACTGCCGGTGGGCCG
CACTGCGGTGACCTGGCTTGAACACTGGCTGGCGATGCGCGATCTGTTCGGGCCGTCAGACGACGCGATGTTCCTGTCCA
ACCAGGGCAAGCGCATCTCGACCCGCAACGTGCAAAAGCGTTTTGCCGAGTGGGGCGTCAAACAGGGCGTTAACAGCCAT
ATCCATCCGCACAAGCTGCGCCACTCGTTTGCCACCCATATGCTGGAGTCGAGCGGCGATCTGCGTGCGGTGCAGGAACT
GCTCGGCCACGCCAATCTGACCACCACTCAAATCTACACCCACCTCGACTTTCAACATCTGGCGAACGTGTACGATGCTG
CGCATCCACGCGCCAAACGGGGGAAATCCTGA

Upstream 100 bases:

>100_bases
GCCGCGATACGCAACACTATCAGCAGGGCATGGGCACCGTGATGCTCAATCAACTGGCGCGCATGCTGCCGGAACTGCTG
GAACGCTGGGTCGAACGCGC

Downstream 100 bases:

>100_bases
TGCATTTTTATCGTCCGCTGCGACCGCTGGCGGCGCTGACTTTTGATCTGGACGACACGCTGTATGACAATCGGCCGGTG
ATCAAACAGACCGAGCTGCA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MIPLAASLQQPVDAFLRYLKVERQLSPLTQLSYSRQLQALMALAQEIGVTEWPLLDAAKVRQLAARSKRAGLQSSSLALR
LSALRSFLDWQVSQGMLIANPAKGIRTPRSGRHLPKNIDVDEMNQLLNIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLD
CRHVDLAAGEIWVLGKGSKERKLPVGRTAVTWLEHWLAMRDLFGPSDDAMFLSNQGKRISTRNVQKRFAEWGVKQGVNSH
IHPHKLRHSFATHMLESSGDLRAVQELLGHANLTTTQIYTHLDFQHLANVYDAAHPRAKRGKS

Sequences:

>Translated_303_residues
MIPLAASLQQPVDAFLRYLKVERQLSPLTQLSYSRQLQALMALAQEIGVTEWPLLDAAKVRQLAARSKRAGLQSSSLALR
LSALRSFLDWQVSQGMLIANPAKGIRTPRSGRHLPKNIDVDEMNQLLNIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLD
CRHVDLAAGEIWVLGKGSKERKLPVGRTAVTWLEHWLAMRDLFGPSDDAMFLSNQGKRISTRNVQKRFAEWGVKQGVNSH
IHPHKLRHSFATHMLESSGDLRAVQELLGHANLTTTQIYTHLDFQHLANVYDAAHPRAKRGKS
>Mature_303_residues
MIPLAASLQQPVDAFLRYLKVERQLSPLTQLSYSRQLQALMALAQEIGVTEWPLLDAAKVRQLAARSKRAGLQSSSLALR
LSALRSFLDWQVSQGMLIANPAKGIRTPRSGRHLPKNIDVDEMNQLLNIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLD
CRHVDLAAGEIWVLGKGSKERKLPVGRTAVTWLEHWLAMRDLFGPSDDAMFLSNQGKRISTRNVQKRFAEWGVKQGVNSH
IHPHKLRHSFATHMLESSGDLRAVQELLGHANLTTTQIYTHLDFQHLANVYDAAHPRAKRGKS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerD binding sites by a short central region, forming

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=73.8983050847458, Blast_Score=466, Evalue=1e-133,
Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=36.6438356164384, Blast_Score=174, Evalue=4e-45,
Organism=Escherichia coli, GI1790768, Length=167, Percent_Identity=28.7425149700599, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790767, Length=182, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33938; Mature: 33938

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPLAASLQQPVDAFLRYLKVERQLSPLTQLSYSRQLQALMALAQEIGVTEWPLLDAAKV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
RQLAARSKRAGLQSSSLALRLSALRSFLDWQVSQGMLIANPAKGIRTPRSGRHLPKNIDV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCHHCCCCCCCCCCCCCCCCH
DEMNQLLNIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLDCRHVDLAAGEIWVLGKGSKE
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCCEEEEECCCCC
RKLPVGRTAVTWLEHWLAMRDLFGPSDDAMFLSNQGKRISTRNVQKRFAEWGVKQGVNSH
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCC
IHPHKLRHSFATHMLESSGDLRAVQELLGHANLTTTQIYTHLDFQHLANVYDAAHPRAKR
CCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHCCCCHHC
GKS
CCC
>Mature Secondary Structure
MIPLAASLQQPVDAFLRYLKVERQLSPLTQLSYSRQLQALMALAQEIGVTEWPLLDAAKV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
RQLAARSKRAGLQSSSLALRLSALRSFLDWQVSQGMLIANPAKGIRTPRSGRHLPKNIDV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCHHCCCCCCCCCCCCCCCCH
DEMNQLLNIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLDCRHVDLAAGEIWVLGKGSKE
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCCEEEEECCCCC
RKLPVGRTAVTWLEHWLAMRDLFGPSDDAMFLSNQGKRISTRNVQKRFAEWGVKQGVNSH
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCC
IHPHKLRHSFATHMLESSGDLRAVQELLGHANLTTTQIYTHLDFQHLANVYDAAHPRAKR
CCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHCCCCHHC
GKS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9555916 [H]