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The map label for this gene is ppiC [H]

Identifier: 157368404

GI number: 157368404

Start: 174168

End: 174503

Strand: Reverse

Name: ppiC [H]

Synonym: Spro_0155

Alternate gene names: 157368404

Gene position: 174503-174168 (Counterclockwise)

Preceding gene: 157368406

Following gene: 157368394

Centisome position: 3.2

GC content: 52.08

Gene sequence:

>336_bases
ATGAGATTTAACGGGTATAATCAGCGCAATTTCTGTATCGATAAAGGCAATACCATGGCAAAGACGGCGTGCGCCCTGCA
CATTCTGGTAGATAACGAAAAACTGGCCGATGAACTGCTGGCCAAGCTTAAACGCGGCGTCAGTTTCGACACCCTGGCGC
GCAAATACTCAACTTGCCCATCAAAACGCAATGGCGGTTCTTTGGGCGAGTTCAACAAGGGCACCATGGTGGCCGCCTTC
GATAAAGCGGTGTTCAGCATTCCGCTGCTCAAGCCCTACGGCCCGGTCAAAACCCAGTTCGGCTACCACATCATCAAAGT
GCTGTATCGCAGCTGA

Upstream 100 bases:

>100_bases
GGTAACGAATTCGACGGCTTGTTGTTGGCTGGGATTTAATCGCATGGCGCTTTATTGCTCGACTTTATAACGTAGGAGGG
GATTGTAGCAGAAAGCGTCG

Downstream 100 bases:

>100_bases
TTGAGGGGGCAAGCGCCCCCTCTATTCTTACTGTGCGCTGGTCTCCGGCGCTGGAGCGGTATCGGTAGGTTTAACTTCTT
CCGATACCACGGCAGGTGCC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase C; Parvulin; Rotamase C [H]

Number of amino acids: Translated: 111; Mature: 111

Protein sequence:

>111_residues
MRFNGYNQRNFCIDKGNTMAKTACALHILVDNEKLADELLAKLKRGVSFDTLARKYSTCPSKRNGGSLGEFNKGTMVAAF
DKAVFSIPLLKPYGPVKTQFGYHIIKVLYRS

Sequences:

>Translated_111_residues
MRFNGYNQRNFCIDKGNTMAKTACALHILVDNEKLADELLAKLKRGVSFDTLARKYSTCPSKRNGGSLGEFNKGTMVAAF
DKAVFSIPLLKPYGPVKTQFGYHIIKVLYRS
>Mature_111_residues
MRFNGYNQRNFCIDKGNTMAKTACALHILVDNEKLADELLAKLKRGVSFDTLARKYSTCPSKRNGGSLGEFNKGTMVAAF
DKAVFSIPLLKPYGPVKTQFGYHIIKVLYRS

Specific function: PPIases accelerate the folding of proteins. It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=93, Percent_Identity=65.5913978494624, Blast_Score=128, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 12411; Mature: 12411

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFNGYNQRNFCIDKGNTMAKTACALHILVDNEKLADELLAKLKRGVSFDTLARKYSTCP
CCCCCCCCCCEEEECCCCHHHHEEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHCCC
SKRNGGSLGEFNKGTMVAAFDKAVFSIPLLKPYGPVKTQFGYHIIKVLYRS
CCCCCCCCCCCCCCCEEEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFNGYNQRNFCIDKGNTMAKTACALHILVDNEKLADELLAKLKRGVSFDTLARKYSTCP
CCCCCCCCCCEEEECCCCHHHHEEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHCCC
SKRNGGSLGEFNKGTMVAAFDKAVFSIPLLKPYGPVKTQFGYHIIKVLYRS
CCCCCCCCCCCCCCCEEEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]