Click here to switch to the map view.

The map label for this gene is ttuB [H]

Identifier: 157368307

GI number: 157368307

Start: 57838

End: 59106

Strand: Reverse

Name: ttuB [H]

Synonym: Spro_0058

Alternate gene names: 157368307

Gene position: 59106-57838 (Counterclockwise)

Preceding gene: 157368308

Following gene: 157368306

Centisome position: 1.08

GC content: 57.21

Gene sequence:

>1269_bases
ATGAACAAAGCGACTATCGCGGCTAAACGCTGGTGGTACATCATGCCCATCGTGTTTATCACCTACAGCCTGGCCTATCT
CGACCGCGCCAACTTCAGCTTTGCTTCGGCCGCCGGCATTAATGACGATCTGGGCATCACCAAGGGCATGTCCTCACTGC
TGGGCGCGCTGTTTTTCCTCGGCTATTTCTTTTTCCAGATCCCCGGCGCTATCTATGCCGAACGCCGCAGCGTTAAAAAA
CTGATTTTCTGGTGCCTGATCCTGTGGGGGGCCTGCGCCTCACTGACCGGCATGGTCAGTAATATCCCCATGCTGGCCGC
TATCCGCTTTATCCTCGGCGTGGTGGAAGCCGCGGTCATGCCGGCGATGCTGATTTACATCAGCAACTGGTTCACCAAAT
CAGAACGCTCACGCGCCAATACCTTCCTGATCCTCGGCAACCCGGTCACGGTGCTGTGGATGTCGGTGGTTTCCGGCTAC
CTGATCCACGCCTACGGCTGGCGTGAAATGTTCATCTTTGAAGGCATTCCGGCGGTGATCTGGGCCTTCTGCTGGTGGGT
GCTGGCCAAAGATAAACCCGCCCAGGCCAAATGGCTGAGCGACGGCGAAAAACTGGCGTTGCAGCAGCAGCTGGAAGAAG
AACAGAAAGGCATTAAAGCGGTGCGTAACTACGGTGAAGCCTTCCGTTCACGCAACGTTATTCTGCTGTGCGCACAGTAC
TTTGCCTGGAGTATCGGCGTGTATGGCTTCGTGCTGTGGTTGCCTTCCATCCTGCGCAGCGGCATGCAGATGGGTATGGT
GGAAGCTGGCTGGCTGTCGGCGGTGCCTTACCTGGCGGCGACTATCGCCATGATCCTGGTGTCCTGGGCCTCCGACAAAA
TGCAAAACCGTAAGCTGTTCGTCTGGCCACTGTTGCTGATTGGCGCGCTGGCTTTCTTCGGCTCTTACGCCGTCGGCGCC
AACCATTTCTGGGTCTCTTACACCCTGTTGGTGATTGCCGGTGCCGCTATGTATGCCCCTTATGGGCCTTTCTTCGCCAT
CATTCCTGAAATGCTGCCGAAAAACGTTGCCGGTGGCGCTATGGCACTGATCAACAGCATGGGTGCACTGGGTTCCTTCT
TCGGCTCGTGGTTTGTCGGTTACCTGAACGGCGCAACCGGTAGCCCGGCGGCTTCTTATATGTTTATGGCTATTGCCCTG
CTGGCGGCGGTGGTGCTGACGCTGGTCGTCAAACCCGCTCGCAACGAGGCCCAGCCACAACTGGCCTGA

Upstream 100 bases:

>100_bases
TAAATATAACAAACATAATCGGTTAACCGACTTCTCCACATGACGTGTACCTCTGGCCCTACAACCAGGACGCGTTGAGA
GAACACTGAGGAATCTGAAC

Downstream 100 bases:

>100_bases
TCTACCTGAATGACCGGGGTGACGGGCGCTGCGCCCTTCACCCTTTTTGCTTTATGTTATGTTGGATCCCCAACGTCCTA
ATCGTTAGCTTGCTGGAGTT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MNKATIAAKRWWYIMPIVFITYSLAYLDRANFSFASAAGINDDLGITKGMSSLLGALFFLGYFFFQIPGAIYAERRSVKK
LIFWCLILWGACASLTGMVSNIPMLAAIRFILGVVEAAVMPAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGY
LIHAYGWREMFIFEGIPAVIWAFCWWVLAKDKPAQAKWLSDGEKLALQQQLEEEQKGIKAVRNYGEAFRSRNVILLCAQY
FAWSIGVYGFVLWLPSILRSGMQMGMVEAGWLSAVPYLAATIAMILVSWASDKMQNRKLFVWPLLLIGALAFFGSYAVGA
NHFWVSYTLLVIAGAAMYAPYGPFFAIIPEMLPKNVAGGAMALINSMGALGSFFGSWFVGYLNGATGSPAASYMFMAIAL
LAAVVLTLVVKPARNEAQPQLA

Sequences:

>Translated_422_residues
MNKATIAAKRWWYIMPIVFITYSLAYLDRANFSFASAAGINDDLGITKGMSSLLGALFFLGYFFFQIPGAIYAERRSVKK
LIFWCLILWGACASLTGMVSNIPMLAAIRFILGVVEAAVMPAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGY
LIHAYGWREMFIFEGIPAVIWAFCWWVLAKDKPAQAKWLSDGEKLALQQQLEEEQKGIKAVRNYGEAFRSRNVILLCAQY
FAWSIGVYGFVLWLPSILRSGMQMGMVEAGWLSAVPYLAATIAMILVSWASDKMQNRKLFVWPLLLIGALAFFGSYAVGA
NHFWVSYTLLVIAGAAMYAPYGPFFAIIPEMLPKNVAGGAMALINSMGALGSFFGSWFVGYLNGATGSPAASYMFMAIAL
LAAVVLTLVVKPARNEAQPQLA
>Mature_422_residues
MNKATIAAKRWWYIMPIVFITYSLAYLDRANFSFASAAGINDDLGITKGMSSLLGALFFLGYFFFQIPGAIYAERRSVKK
LIFWCLILWGACASLTGMVSNIPMLAAIRFILGVVEAAVMPAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGY
LIHAYGWREMFIFEGIPAVIWAFCWWVLAKDKPAQAKWLSDGEKLALQQQLEEEQKGIKAVRNYGEAFRSRNVILLCAQY
FAWSIGVYGFVLWLPSILRSGMQMGMVEAGWLSAVPYLAATIAMILVSWASDKMQNRKLFVWPLLLIGALAFFGSYAVGA
NHFWVSYTLLVIAGAAMYAPYGPFFAIIPEMLPKNVAGGAMALINSMGALGSFFGSWFVGYLNGATGSPAASYMFMAIAL
LAAVVLTLVVKPARNEAQPQLA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=247, Percent_Identity=25.1012145748988, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI9966811, Length=381, Percent_Identity=22.5721784776903, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI87082071, Length=428, Percent_Identity=24.7663551401869, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI87082320, Length=424, Percent_Identity=23.8207547169811, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789152, Length=436, Percent_Identity=24.5412844036697, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI2367379, Length=278, Percent_Identity=22.3021582733813, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789515, Length=435, Percent_Identity=24.367816091954, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI2367193, Length=420, Percent_Identity=24.5238095238095, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87082404, Length=387, Percent_Identity=24.5478036175711, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI86561091, Length=252, Percent_Identity=26.5873015873016, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25141318, Length=252, Percent_Identity=26.5873015873016, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25141316, Length=252, Percent_Identity=26.5873015873016, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115533556, Length=343, Percent_Identity=26.2390670553936, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115533554, Length=362, Percent_Identity=25.414364640884, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25141341, Length=200, Percent_Identity=27, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17535049, Length=434, Percent_Identity=24.8847926267281, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI32565916, Length=196, Percent_Identity=24.4897959183673, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI32565914, Length=196, Percent_Identity=24.4897959183673, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17552542, Length=321, Percent_Identity=24.6105919003115, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193205400, Length=194, Percent_Identity=25.7731958762887, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560030, Length=253, Percent_Identity=20.1581027667984, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322612, Length=220, Percent_Identity=24.5454545454545, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322973, Length=130, Percent_Identity=28.4615384615385, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550460, Length=408, Percent_Identity=23.5294117647059, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24580790, Length=349, Percent_Identity=23.4957020057307, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24655255, Length=370, Percent_Identity=23.5135135135135, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24648416, Length=278, Percent_Identity=26.978417266187, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356189, Length=278, Percent_Identity=26.978417266187, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573708, Length=343, Percent_Identity=24.198250728863, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28573707, Length=343, Percent_Identity=24.198250728863, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24583789, Length=363, Percent_Identity=22.3140495867769, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24655271, Length=400, Percent_Identity=23, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI20130135, Length=393, Percent_Identity=23.1552162849873, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24653727, Length=389, Percent_Identity=24.9357326478149, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573299, Length=307, Percent_Identity=22.1498371335505, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24584153, Length=378, Percent_Identity=21.1640211640212, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24641682, Length=372, Percent_Identity=23.1182795698925, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24658674, Length=285, Percent_Identity=21.4035087719298, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46616; Mature: 46616

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKATIAAKRWWYIMPIVFITYSLAYLDRANFSFASAAGINDDLGITKGMSSLLGALFFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHH
GYFFFQIPGAIYAERRSVKKLIFWCLILWGACASLTGMVSNIPMLAAIRFILGVVEAAVM
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
PAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGYLIHAYGWREMFIFEGIPAVI
HHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHH
WAFCWWVLAKDKPAQAKWLSDGEKLALQQQLEEEQKGIKAVRNYGEAFRSRNVILLCAQY
HHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHH
FAWSIGVYGFVLWLPSILRSGMQMGMVEAGWLSAVPYLAATIAMILVSWASDKMQNRKLF
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VWPLLLIGALAFFGSYAVGANHFWVSYTLLVIAGAAMYAPYGPFFAIIPEMLPKNVAGGA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHH
MALINSMGALGSFFGSWFVGYLNGATGSPAASYMFMAIALLAAVVLTLVVKPARNEAQPQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LA
CC
>Mature Secondary Structure
MNKATIAAKRWWYIMPIVFITYSLAYLDRANFSFASAAGINDDLGITKGMSSLLGALFFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHH
GYFFFQIPGAIYAERRSVKKLIFWCLILWGACASLTGMVSNIPMLAAIRFILGVVEAAVM
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
PAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGYLIHAYGWREMFIFEGIPAVI
HHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHH
WAFCWWVLAKDKPAQAKWLSDGEKLALQQQLEEEQKGIKAVRNYGEAFRSRNVILLCAQY
HHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHH
FAWSIGVYGFVLWLPSILRSGMQMGMVEAGWLSAVPYLAATIAMILVSWASDKMQNRKLF
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VWPLLLIGALAFFGSYAVGANHFWVSYTLLVIAGAAMYAPYGPFFAIIPEMLPKNVAGGA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHH
MALINSMGALGSFFGSWFVGYLNGATGSPAASYMFMAIALLAAVVLTLVVKPARNEAQPQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]