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The map label for this gene is atpD [H]

Identifier: 157368257

GI number: 157368257

Start: 5664

End: 7046

Strand: Direct

Name: atpD [H]

Synonym: Spro_0008

Alternate gene names: 157368257

Gene position: 5664-7046 (Clockwise)

Preceding gene: 157368256

Following gene: 157368258

Centisome position: 0.1

GC content: 53.72

Gene sequence:

>1383_bases
ATGGCTACTGGAAAGATTATCCAGGTAATCGGCGCCGTAGTGGACGTCGAGTTCCCTCAGGATGCCGTACCAAAAGTGTA
CAACGCTCTTGAGGTAGAAAACGGTGCCAATAAGCTGGTGCTGGAAGTTCAGCAACAGTTGGGCGGTGGCGTGGTTCGCT
GTATCGCAATGGGGACCTCTGATGGTCTGCGTCGCGGTCTGAAAGTCACTGACCTGGACCACCCAATTGAAGTACCGGTA
GGTAAAGCTACCCTGGGCCGTATCATGAACGTATTGGGTGAACCAATCGACATGAAGGGCGATATCGGCGAAGAAGAACG
TTGGGCGATTCACCGTCCGGCGCCAAGCTACGAAGATTTGGCCAACTCCCAGGATCTGCTGGAAACCGGTATCAAGGTAA
TGGACCTGATCTGCCCGTTCGCCAAGGGTGGTAAAGTCGGTCTGTTCGGTGGTGCGGGTGTTGGTAAAACCGTAAACATG
ATGGAGCTGATCCGTAACATCGCGATCGAGCACTCCGGTTATTCTGTGTTTGCGGGCGTGGGTGAGCGTACTCGTGAGGG
TAACGACTTCTACCACGAAATGAACGACTCCAACGTACTGGATAAAGTATCCCTGGTTTACGGCCAGATGAACGAGCCAC
CGGGTAACCGTCTGCGCGTTGCTCTGACCGGTCTGACCATGGCGGAGAAATTCCGTGACGAAGGCCGTGACGTTCTGCTG
TTCGTTGATAACATCTACCGTTATACCCTGGCCGGTACCGAAGTGTCCGCACTTCTGGGCCGTATGCCATCGGCGGTAGG
TTATCAGCCAACGCTGGCGGAAGAGATGGGTGTTCTGCAAGAACGTATCACCTCTACCAAGACCGGTTCAATCACCTCCG
TACAGGCCGTTTACGTCCCTGCGGATGACTTGACTGACCCGTCACCAGCCACCACCTTTGCTCACTTGGATGCAACTGTG
GTACTGAGCCGTAATATCGCTTCTCTGGGTATCTACCCGGCCGTTGACCCGCTGGATTCTACCAGCCGTCAGCTGGATCC
GCTGGTAGTTGGCCAGGAGCACTACGATGTAGCGCGTGGCGTGCAGTCCATTCTGCAACGCTATCAGGAACTGAAAGATA
TTATCGCAATCCTGGGTATGGACGAGCTGTCTGAAGAAGACAAACTGGTCGTATCCCGTGCGCGTAAAATCCAACGCTTC
CTGTCTCAGCCGTTCTTCGTGGCAGAAGTCTTCACCGGTTCTCCGGGCAAGTTCGTATCGCTGAAAGACACCATTCGTGG
TTTCAAAGGCATTATGGACGGCGACTATGACCACCTGCCTGAACAAGCGTTCTACATGGTTGGCACCATTGAAGAAGCAG
TGGAAAAAGCCAAGAAACTGTAA

Upstream 100 bases:

>100_bases
ACAAGGCTCGTCAGGCCAGCATCACTCAGGAACTCACCGAGATCGTTTCGGGAGCCTCCGCGGTTTAAGCTAGGTTTACG
AATTACGTAGAGGATTCAAG

Downstream 100 bases:

>100_bases
CGTCTTGAGAGGAGGGTGATATGGCTATGACTTACCATCTGGATGTAGTCAGCGCGGAAAAACATATGTTTTCCGGCCTG
GTGCAAAAGATCCAGGTGAC

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MATGKIIQVIGAVVDVEFPQDAVPKVYNALEVENGANKLVLEVQQQLGGGVVRCIAMGTSDGLRRGLKVTDLDHPIEVPV
GKATLGRIMNVLGEPIDMKGDIGEEERWAIHRPAPSYEDLANSQDLLETGIKVMDLICPFAKGGKVGLFGGAGVGKTVNM
MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMNDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLL
FVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATV
VLSRNIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARGVQSILQRYQELKDIIAILGMDELSEEDKLVVSRARKIQRF
LSQPFFVAEVFTGSPGKFVSLKDTIRGFKGIMDGDYDHLPEQAFYMVGTIEEAVEKAKKL

Sequences:

>Translated_460_residues
MATGKIIQVIGAVVDVEFPQDAVPKVYNALEVENGANKLVLEVQQQLGGGVVRCIAMGTSDGLRRGLKVTDLDHPIEVPV
GKATLGRIMNVLGEPIDMKGDIGEEERWAIHRPAPSYEDLANSQDLLETGIKVMDLICPFAKGGKVGLFGGAGVGKTVNM
MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMNDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLL
FVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATV
VLSRNIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARGVQSILQRYQELKDIIAILGMDELSEEDKLVVSRARKIQRF
LSQPFFVAEVFTGSPGKFVSLKDTIRGFKGIMDGDYDHLPEQAFYMVGTIEEAVEKAKKL
>Mature_459_residues
ATGKIIQVIGAVVDVEFPQDAVPKVYNALEVENGANKLVLEVQQQLGGGVVRCIAMGTSDGLRRGLKVTDLDHPIEVPVG
KATLGRIMNVLGEPIDMKGDIGEEERWAIHRPAPSYEDLANSQDLLETGIKVMDLICPFAKGGKVGLFGGAGVGKTVNMM
ELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMNDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLF
VDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVV
LSRNIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARGVQSILQRYQELKDIIAILGMDELSEEDKLVVSRARKIQRFL
SQPFFVAEVFTGSPGKFVSLKDTIRGFKGIMDGDYDHLPEQAFYMVGTIEEAVEKAKKL

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=466, Percent_Identity=70.8154506437768, Blast_Score=655, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=321, Percent_Identity=28.0373831775701, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI19913428, Length=356, Percent_Identity=23.876404494382, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI19913426, Length=356, Percent_Identity=23.314606741573, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI50345984, Length=395, Percent_Identity=24.0506329113924, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4757810, Length=395, Percent_Identity=24.0506329113924, Blast_Score=96, Evalue=5e-20,
Organism=Escherichia coli, GI1790170, Length=460, Percent_Identity=93.4782608695652, Blast_Score=887, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=303, Percent_Identity=30.03300330033, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1790172, Length=420, Percent_Identity=25, Blast_Score=113, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=466, Percent_Identity=69.0987124463519, Blast_Score=642, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=321, Percent_Identity=28.9719626168224, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17510931, Length=349, Percent_Identity=24.9283667621776, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17570191, Length=418, Percent_Identity=23.9234449760766, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71988080, Length=367, Percent_Identity=23.9782016348774, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988063, Length=367, Percent_Identity=23.9782016348774, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71988074, Length=373, Percent_Identity=23.5924932975871, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322581, Length=458, Percent_Identity=68.1222707423581, Blast_Score=628, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=349, Percent_Identity=25.7879656160458, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319370, Length=368, Percent_Identity=24.7282608695652, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320016, Length=233, Percent_Identity=27.8969957081545, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24638766, Length=465, Percent_Identity=69.8924731182796, Blast_Score=646, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=465, Percent_Identity=64.9462365591398, Blast_Score=596, Evalue=1e-170,
Organism=Drosophila melanogaster, GI24583992, Length=321, Percent_Identity=27.7258566978193, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24583988, Length=351, Percent_Identity=26.7806267806268, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24583986, Length=351, Percent_Identity=26.7806267806268, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24583984, Length=351, Percent_Identity=26.7806267806268, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI20129479, Length=331, Percent_Identity=28.0966767371601, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24638768, Length=92, Percent_Identity=57.6086956521739, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281361666, Length=349, Percent_Identity=24.3553008595989, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24646341, Length=349, Percent_Identity=24.3553008595989, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17136796, Length=349, Percent_Identity=24.3553008595989, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24658560, Length=367, Percent_Identity=23.9782016348774, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 50165; Mature: 50034

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGKIIQVIGAVVDVEFPQDAVPKVYNALEVENGANKLVLEVQQQLGGGVVRCIAMGTS
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEECCC
DGLRRGLKVTDLDHPIEVPVGKATLGRIMNVLGEPIDMKGDIGEEERWAIHRPAPSYEDL
HHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHH
ANSQDLLETGIKVMDLICPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGV
CCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECC
GERTREGNDFYHEMNDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLL
CCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHCCCEEEE
FVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVP
EEECCEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEC
ADDLTDPSPATTFAHLDATVVLSRNIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARG
CCCCCCCCCCCEEHHCCEEEEEECCHHHCCCCCCCCCCCCCHHHCCCEEECCHHHHHHHH
VQSILQRYQELKDIIAILGMDELSEEDKLVVSRARKIQRFLSQPFFVAEVFTGSPGKFVS
HHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEE
LKDTIRGFKGIMDGDYDHLPEQAFYMVGTIEEAVEKAKKL
HHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATGKIIQVIGAVVDVEFPQDAVPKVYNALEVENGANKLVLEVQQQLGGGVVRCIAMGTS
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEECCC
DGLRRGLKVTDLDHPIEVPVGKATLGRIMNVLGEPIDMKGDIGEEERWAIHRPAPSYEDL
HHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHH
ANSQDLLETGIKVMDLICPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGV
CCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECC
GERTREGNDFYHEMNDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLL
CCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHCCCEEEE
FVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVP
EEECCEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEC
ADDLTDPSPATTFAHLDATVVLSRNIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARG
CCCCCCCCCCCEEHHCCEEEEEECCHHHCCCCCCCCCCCCCHHHCCCEEECCHHHHHHHH
VQSILQRYQELKDIIAILGMDELSEEDKLVVSRARKIQRFLSQPFFVAEVFTGSPGKFVS
HHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEE
LKDTIRGFKGIMDGDYDHLPEQAFYMVGTIEEAVEKAKKL
HHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA