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The map label for this gene is yhcM [H]

Identifier: 157159011

GI number: 157159011

Start: 3708955

End: 3710082

Strand: Reverse

Name: yhcM [H]

Synonym: EcE24377A_3715

Alternate gene names: 157159011

Gene position: 3710082-3708955 (Counterclockwise)

Preceding gene: 157155698

Following gene: 157154937

Centisome position: 74.51

GC content: 51.86

Gene sequence:

>1128_bases
ATGCAAAGCGTTACCCCAACATCGCAATACCTGAAGGCGCTCAATGAAGGCAGCCATCAACCCGACGACGTTCAAAAAGA
GGCCGTCAGCCGCCTGGAAATTATTTATCAAGAACTCATCAATAGCAGGCCACCAGCCCCCAGGACGAGTGGGCTAATGG
CGCGGGTCGGTAAGCTGTGGGGTAAACGCGAAGACACAAAGCATACGCCAGTGCGTGGCTTATATATGTGGGGCGGTGTA
GGACGCGGGAAAACCTGGCTGATGGACCTTTTCTATCAAAGCCTGCTGGGAGAGCGGAAACAGCGCCTGCACTTTCACCG
TTTTATGCTGCGGGTGCACGAAGAGCTAACTGCCTTACAGGGGCAGACCGATCCGCTGGAAATTATTGCCGATCGCTTTA
AAGCCGAAACTGACGTGCTCTGTTTTGACGAATTTTTTGTTTCTGATATTACCGACGCCATGCTACTTGGCGGTCTGATG
AAAGCCCTGTTCGCTCGCGGAATAACGTTGGTCGCAACGTCAAATATTCCGCCGGACGAACTTTATCGAAATGGCTTGCA
ACGTGCACGTTTTTTGCCTGCAATCGATGCCATTAAACAGCATTGTGATGTAATGAACGTGGACGCTGGTGTTGATTATC
GACTGCGTACACTCACTCAGGCGCATCTGTGGCTTTCGCCACTCAACGATGAAACCCGGGCGCAGATGGATAAACTATGG
TTGGCGCTGGCGGGGGCGAAACGAGAAAATTCACCGACGTTAGAAATCAACCATCGGCCATTGGCGACAATGGGCGTCGA
GAACCAGACGCTGGCGGTCTCTTTTACTACGCTGTGCGTCGACGCCCGCAGTCAGCATGACTATATTGCGCTCTCACGTC
TCTTTCATACGGTCATGTTGTTTGATGTACCAGTTATGACGCGGTTGATGGAGAGCGAAGCGCGGCGCTTTATTGCGCTG
GTGGATGAGTTTTACGAGCGCCATGTCAAATTAGTGGTGAGTGCAGAAGTGCCGCTGTATGAAATTTATCAGGGCGATCG
GCTGAAGTTTGAGTTCCAGCGTTGCCTGTCACGTCTGCAAGAGATGCAAAGCGAAGAGTATCTGAAGCGCGAGCATTTGG
CGGGTTAA

Upstream 100 bases:

>100_bases
AAGTGGAATCCCGACTGCATATCGCGTAGTGTAGAACGGCCTTTTTTTCGTCAACCGTGAACAACGGCGCACCGATTATT
CAAGGAATAACAATAAGATC

Downstream 100 bases:

>100_bases
AACCTGTCACAAATCACAAAAAGGGGTCGATCTTTGACCCCGACTTCTCTATAATCCTGCGACCCCACGTTACAAGAAAG
TTTTTTTCCCAAAACTTTTT

Product: AFG1 family ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSRPPAPRTSGLMARVGKLWGKREDTKHTPVRGLYMWGGV
GRGKTWLMDLFYQSLLGERKQRLHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLM
KALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTLTQAHLWLSPLNDETRAQMDKLW
LALAGAKRENSPTLEINHRPLATMGVENQTLAVSFTTLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIAL
VDEFYERHVKLVVSAEVPLYEIYQGDRLKFEFQRCLSRLQEMQSEEYLKREHLAG

Sequences:

>Translated_375_residues
MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSRPPAPRTSGLMARVGKLWGKREDTKHTPVRGLYMWGGV
GRGKTWLMDLFYQSLLGERKQRLHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLM
KALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTLTQAHLWLSPLNDETRAQMDKLW
LALAGAKRENSPTLEINHRPLATMGVENQTLAVSFTTLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIAL
VDEFYERHVKLVVSAEVPLYEIYQGDRLKFEFQRCLSRLQEMQSEEYLKREHLAG
>Mature_375_residues
MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSRPPAPRTSGLMARVGKLWGKREDTKHTPVRGLYMWGGV
GRGKTWLMDLFYQSLLGERKQRLHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLM
KALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTLTQAHLWLSPLNDETRAQMDKLW
LALAGAKRENSPTLEINHRPLATMGVENQTLAVSFTTLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIAL
VDEFYERHVKLVVSAEVPLYEIYQGDRLKFEFQRCLSRLQEMQSEEYLKREHLAG

Specific function: Unknown

COG id: COG1485

COG function: function code R; Predicted ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AFG1 ATPase family [H]

Homologues:

Organism=Homo sapiens, GI21918872, Length=433, Percent_Identity=33.4872979214781, Blast_Score=223, Evalue=2e-58,
Organism=Escherichia coli, GI1789627, Length=375, Percent_Identity=98.9333333333333, Blast_Score=769, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17505769, Length=416, Percent_Identity=33.6538461538462, Blast_Score=241, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6320783, Length=393, Percent_Identity=29.7709923664122, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI20129913, Length=426, Percent_Identity=30.9859154929577, Blast_Score=192, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005654 [H]

Pfam domain/function: PF03969 AFG1_ATPase [H]

EC number: NA

Molecular weight: Translated: 43126; Mature: 43126

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSRPPAPRTSGLMARVGKLW
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
GKREDTKHTPVRGLYMWGGVGRGKTWLMDLFYQSLLGERKQRLHFHRFMLRVHEELTALQ
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLMKALFARGITLVATSNIPPDE
CCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHH
LYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTLTQAHLWLSPLNDETRAQMDKLW
HHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LALAGAKRENSPTLEINHRPLATMGVENQTLAVSFTTLCVDARSQHDYIALSRLFHTVML
HHHHCCCCCCCCEEEECCCCCEEECCCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHH
FDVPVMTRLMESEARRFIALVDEFYERHVKLVVSAEVPLYEIYQGDRLKFEFQRCLSRLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHCCCCHHHHHHHHHHHHH
EMQSEEYLKREHLAG
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSRPPAPRTSGLMARVGKLW
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
GKREDTKHTPVRGLYMWGGVGRGKTWLMDLFYQSLLGERKQRLHFHRFMLRVHEELTALQ
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLMKALFARGITLVATSNIPPDE
CCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHH
LYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTLTQAHLWLSPLNDETRAQMDKLW
HHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LALAGAKRENSPTLEINHRPLATMGVENQTLAVSFTTLCVDARSQHDYIALSRLFHTVML
HHHHCCCCCCCCEEEECCCCCEEECCCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHH
FDVPVMTRLMESEARRFIALVDEFYERHVKLVVSAEVPLYEIYQGDRLKFEFQRCLSRLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHCCCCHHHHHHHHHHHHH
EMQSEEYLKREHLAG
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]