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The map label for this gene is cscK [H]

Identifier: 157158692

GI number: 157158692

Start: 2638666

End: 2639580

Strand: Reverse

Name: cscK [H]

Synonym: EcE24377A_2647

Alternate gene names: 157158692

Gene position: 2639580-2638666 (Counterclockwise)

Preceding gene: 157156023

Following gene: 157154895

Centisome position: 53.01

GC content: 52.02

Gene sequence:

>915_bases
ATGTCAGCCAAAGTATGGGTTTTAGGGGATGCGGTCGTAGATCTCTTGCCAGAATCAGACGGGCGGCTACTGCCTTGTCC
TGGCGGCGCGCCAGCTAACGTTGCGGTGGGAATCGCCAGATTAGGCGGAATAAGTGGGTTTATAGGTCGGGTCGGTGATG
ATCCTTTTGGGGCGTTAATGCAAAGAACGCTGCTAACTGAGGGAGTCGATATCACGTATCTGAAGCAAGATGAATGGCAC
CGGACATCCACGGTGCTTGTCGATCTGAACGATCAAGGGGAACGTTCATTTACGTTTATGGTCCGCCCCAGTGCCGATCT
TTTTTTAGAGACGACAGACTTGCCCTGCTGGCGACATGGCGAATGGTTACATCTCTGTTCAATTGCGTTGTCTGCCGAGC
CTTCGCGTACCAGCGCATTTACTGCGATGACGGCGATCCGGCATGCCGGAGGTTTTGTCAGCTTCGATCCTAATATTCGT
GAAGATCTATGGCAAGACGAGCATTTGCTCCGCTTGTGTTTGCGGCAGGCGCTACAACTGGCGGATGTCGTCAAGCTCTC
GGAAGAAGAATGGCGACTTATCAGTGGAAAAACACAGAACGATCGGGATATATGCGCCCTGGCAAAAGAGTATGAGATCG
CCATGCTGTTGGTGACTAAAGGTGCAGAAGGTGTGGTGGTCTGTTATCGAGGACAAGTTCACCATTTTGCTGGAATGTCT
GTGAATTGTGTCGATAGCACGGGGGCGGGAGATGCGTTCGTTGCCGGGTTACTCACAGGTCTGTCCTCTACGGGATTATC
TACAGATGAGAGAGAAATGCGACGAATTATCGATCTCGCTCAACGTTGCGGAGCGCTTGCAGTAACGGCGAAAGGGGCAA
TGACAGCGCTGCCATGTCGACAAGAACTGGAATAG

Upstream 100 bases:

>100_bases
CGTTTTGTGATCGAATATGCATGTTTTAGTAAATCCATGACGATTTTGCGAAAAAGAGGTTTATCACTATGCGTAAGTCA
GATGAATTTAAGGGAAAAAA

Downstream 100 bases:

>100_bases
TGAGAAGTAAACGGCGAAGTCGCTCTTATCTCTAAATAGGACGTGAATTTTTTAACGACAGGCAGGTAATTATGGCACTG
AATATTCCATTCAGAAATGC

Product: aminoimidazole riboside kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGISGFIGRVGDDPFGALMQRTLLTEGVDITYLKQDEWH
RTSTVLVDLNDQGERSFTFMVRPSADLFLETTDLPCWRHGEWLHLCSIALSAEPSRTSAFTAMTAIRHAGGFVSFDPNIR
EDLWQDEHLLRLCLRQALQLADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLVTKGAEGVVVCYRGQVHHFAGMS
VNCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRIIDLAQRCGALAVTAKGAMTALPCRQELE

Sequences:

>Translated_304_residues
MSAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGISGFIGRVGDDPFGALMQRTLLTEGVDITYLKQDEWH
RTSTVLVDLNDQGERSFTFMVRPSADLFLETTDLPCWRHGEWLHLCSIALSAEPSRTSAFTAMTAIRHAGGFVSFDPNIR
EDLWQDEHLLRLCLRQALQLADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLVTKGAEGVVVCYRGQVHHFAGMS
VNCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRIIDLAQRCGALAVTAKGAMTALPCRQELE
>Mature_303_residues
SAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGISGFIGRVGDDPFGALMQRTLLTEGVDITYLKQDEWHR
TSTVLVDLNDQGERSFTFMVRPSADLFLETTDLPCWRHGEWLHLCSIALSAEPSRTSAFTAMTAIRHAGGFVSFDPNIRE
DLWQDEHLLRLCLRQALQLADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLVTKGAEGVVVCYRGQVHHFAGMSV
NCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRIIDLAQRCGALAVTAKGAMTALPCRQELE

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=294, Percent_Identity=26.8707482993197, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1790193, Length=281, Percent_Identity=26.6903914590747, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI87082281, Length=273, Percent_Identity=25.2747252747253, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082343, Length=303, Percent_Identity=27.0627062706271, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=284, Percent_Identity=27.4647887323944, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.4 [H]

Molecular weight: Translated: 33061; Mature: 32930

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGISGFIGRVGDDPFGALM
CCCEEEEECHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHH
QRTLLTEGVDITYLKQDEWHRTSTVLVDLNDQGERSFTFMVRPSADLFLETTDLPCWRHG
HHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCEEEEEECCCCCEEEEECCCCCCCCC
EWLHLCSIALSAEPSRTSAFTAMTAIRHAGGFVSFDPNIREDLWQDEHLLRLCLRQALQL
CCEEEEEEHCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHH
ADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLVTKGAEGVVVCYRGQVHHFAGMS
HHHHHCCCCCEEEECCCCCCCCHHHHHHHCCEEEEEEEECCCCEEEEEEECCEEEECCCE
VNCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRIIDLAQRCGALAVTAKGAMTALPCR
EEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCEEECCCH
QELE
HHCC
>Mature Secondary Structure 
SAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGISGFIGRVGDDPFGALM
CCEEEEECHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHH
QRTLLTEGVDITYLKQDEWHRTSTVLVDLNDQGERSFTFMVRPSADLFLETTDLPCWRHG
HHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCEEEEEECCCCCEEEEECCCCCCCCC
EWLHLCSIALSAEPSRTSAFTAMTAIRHAGGFVSFDPNIREDLWQDEHLLRLCLRQALQL
CCEEEEEEHCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHH
ADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLVTKGAEGVVVCYRGQVHHFAGMS
HHHHHCCCCCEEEECCCCCCCCHHHHHHHCCEEEEEEEECCCCEEEEEEECCEEEECCCE
VNCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRIIDLAQRCGALAVTAKGAMTALPCR
EEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCEEECCCH
QELE
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA