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The map label for this gene is ylaB [H]

Identifier: 157158408

GI number: 157158408

Start: 512214

End: 513770

Strand: Reverse

Name: ylaB [H]

Synonym: EcE24377A_0492

Alternate gene names: 157158408

Gene position: 513770-512214 (Counterclockwise)

Preceding gene: 157156260

Following gene: 157157382

Centisome position: 10.32

GC content: 48.04

Gene sequence:

>1557_bases
ATGCTGGTGAGAACACGACATCTGGTCGGCCTTATTTCGGGAGTACTGATTCTTTCAGTATTGCTGCCTGTCGGCTTAAG
CATCTGGCTGGCCCATCAGCAGGTAGAAACATCGTTTATTGAAGAGCTGGATACCTATTCCTCCCGCGTCGCTATTCGGG
CCAATAAGGTGGCGACACAAGGGAAAGATGCGCTGCAAGAGCTGGAAAGATGGCAAGGCGCTGCCTGTAGCGAAGCCCAT
CTCATGGAAATGCGTCGGGTATCTTACAGTTATCGCTATATTCAGGAAGTGGTTTATATCGATAACAACGTTCCCCAGTG
TTCGTCTCTGGAGCATGAAAGTCCGCCCGATACCTTCCCCGAGCCAGGTAAAATTTCGAAAGATGGTTATCGTGTCTGGT
TAACATCGCATAACGATTTAGGCATTATCCGTTACATGGTCGCCATGGGAACGGCACATTATGTCGTCATGATCGACCCC
GCTTCCTTTATTGATGTCATTCCCTATAGCTCATGGCAAATTGATGCCGCCATTATTGGCAATGCCCATAACGTTGTCAT
AACCAGCAGCGATGAAATTGCTCAGGGAATTATTACCAGGCTACAAAAAACACCCGGTGAGCATATCGAAAATAATGGAA
TCATTTACGATATCCTGCCCTTCCCGGAGATGAATATTTCGATCATCACCTGGGCTTCAACGAAAATGTTGCAGAAAGGC
TGGCATCGGCAAGTCTTTATTTGGTTACCGCTCGGGTTGGTGATTGGCCTGCTGGCAGCGATGTTTGTGCTGCGTATTTT
GCGCCGTATCCAGTCACCGCATCATCGGCTGCAGGATGCTATCGAAAATCGTGATATTTGCGTGCACTATCAGCCGATTG
TCTCCTTAGCCAATGGCAAAATTGTCGGTGCTGAGGCACTGGCGCGCTGGCCGCAGACAGACGGTAGTTGGTTGTCACCA
GATAGTTTTATTCCGCTGGCACAGCAAACGGGCCTTTCTGAGCCATTGACGCTACTGATTATAAGAAGCGTCTTTGAAGA
TATGGGCGACTGGCTGCGTCAGCATCCACAGCAGCATATTTCGATCAATCTTGAATCCACCGTGCTCACCTCGGAAAAAA
TCCCGCAATTGCTGCGTGAAATGATCAATCACTATCAGGTTAATCCCAGACAGATCGCGCTTGAACTCACTGAACGCGAG
TTTGCCGATCCGAAAACCAGCGCCCCGATAATTTCTCGCTACCGGGAGGCGGGCCATGAAATTTATCTTGATGATTTTGG
TACGGGATATTCAAGTTTAAGTTATTTACAGGATCTGGATGTCGACATTCTGAAGATCGATAAATCTTTCGTTGATGCGC
TGGAATATAAAAATGTCACGCCGCATATCATCGAAATGGCAAAAACACTGAAACTGAAAATGGTAGCGGAGGGAATCGAA
ACCAGTAAACAAGAAGAGTGGCTACGCCAGCATGGCGTGCACTACGGTCAGGGCTGGCTCTACAGCAAGGCATTACCGAA
AGAAGATTTCTTACGCTGGGCCGAGCAACATTTGTGA

Upstream 100 bases:

>100_bases
TCCACCCATCACTTCATGAAATACCAGCTCTACCTCCTTATCTCCTGCCAGCCTTTTTCCACAATCAGATATACTTTCCC
TACACTGTGTTAATAAGGAT

Downstream 100 bases:

>100_bases
ATTTTTGGGCTGACGGCACGCCGCACAGCCCGTCACGCTACCTATTCGTCGATGATTGACTCGAATCCGCCATAGATCAT
TCGCTTGCCGTCAAACGGCA

Product: cyclic diguanylate phosphodiesterase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MLVRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQGKDALQELERWQGAACSEAH
LMEMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDP
ASFIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPFPEMNISIITWASTKMLQKG
WHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSP
DSFIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIALELTERE
FADPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIE
TSKQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL

Sequences:

>Translated_518_residues
MLVRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQGKDALQELERWQGAACSEAH
LMEMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDP
ASFIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPFPEMNISIITWASTKMLQKG
WHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSP
DSFIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIALELTERE
FADPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIE
TSKQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL
>Mature_518_residues
MLVRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQGKDALQELERWQGAACSEAH
LMEMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDP
ASFIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPFPEMNISIITWASTKMLQKG
WHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSP
DSFIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIALELTERE
FADPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIE
TSKQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL

Specific function: Unknown

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI87081743, Length=516, Percent_Identity=99.031007751938, Blast_Score=1051, Evalue=0.0,
Organism=Escherichia coli, GI1790496, Length=528, Percent_Identity=33.7121212121212, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI87081845, Length=293, Percent_Identity=34.4709897610922, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI226510982, Length=237, Percent_Identity=35.8649789029536, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788502, Length=270, Percent_Identity=31.4814814814815, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1787541, Length=247, Percent_Identity=30.3643724696356, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI87081980, Length=236, Percent_Identity=36.4406779661017, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786507, Length=245, Percent_Identity=33.0612244897959, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1788849, Length=263, Percent_Identity=30.4182509505703, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI87081921, Length=245, Percent_Identity=33.469387755102, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI87082096, Length=242, Percent_Identity=30.9917355371901, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1787055, Length=241, Percent_Identity=26.9709543568465, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 59014; Mature: 59014

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHC
GKDALQELERWQGAACSEAHLMEMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFP
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
EPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPASFIDVIPYSSWQIDAAIIG
CCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCEEEEEEEC
NAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPFPEMNISIITWASTKMLQKG
CCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEEECHHHHHHCC
WHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGK
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEHHHHHHCCCC
IVGAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHI
EECHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHE
SINLESTVLTSEKIPQLLREMINHYQVNPRQIALELTEREFADPKTSAPIISRYREAGHE
EEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEHHHHCCCCCCCCHHHHHHHHCCCE
IYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIE
EEEECCCCCHHHHHHHHHCCCHHEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TSKQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL
CCHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLVRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHC
GKDALQELERWQGAACSEAHLMEMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFP
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
EPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPASFIDVIPYSSWQIDAAIIG
CCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCEEEEEEEC
NAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPFPEMNISIITWASTKMLQKG
CCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEEECHHHHHHCC
WHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGK
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEHHHHHHCCCC
IVGAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHI
EECHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHE
SINLESTVLTSEKIPQLLREMINHYQVNPRQIALELTEREFADPKTSAPIISRYREAGHE
EEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEHHHHCCCCCCCCHHHHHHHHCCCE
IYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIE
EEEECCCCCHHHHHHHHHCCCHHEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TSKQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL
CCHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]