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The map label for this gene is sorE [H]

Identifier: 157158379

GI number: 157158379

Start: 3283002

End: 3284279

Strand: Reverse

Name: sorE [H]

Synonym: EcE24377A_3266

Alternate gene names: 157158379

Gene position: 3284279-3283002 (Counterclockwise)

Preceding gene: 157155472

Following gene: 157158644

Centisome position: 65.95

GC content: 51.25

Gene sequence:

>1278_bases
ATGAAAACCAAAGTTGCTGCTATTTATGGCAAGCGGGATGTCCGTCTGCGCGAATTTGAACTGCCAGAAATTACCGATAA
TGAACTGTTAGTGAGTGTAATTTCTGACAGCGTCTGTTTATCGACCTGGAAAGCGGCGTTACTCGGTAGTGAACATAAAC
GCGTACCCGACGATTTAGAAAATCATCCGGTCATTACCGGGCATGAATGTGCCGGGGTTATTGTCGAAGTGGGTAAAAAT
CTCACTGGCAAATATAAAAAAGGCCAGCGTTTTGTATTGCAACCGGCGATGGGGTTACCAAGCGGATATTCAGCAGGCTA
CAGCTACGAATATTTTGGCGGTAACGCCACCTATATGATTATTCCCGAAATCGCCATTAATTTGGGCTGCGTATTACCGT
ATCACGGCTCTTATTTTGCTGCGGCGTCGCTGGCAGAGCCTATGTGCTGCATTATTGGTGCTTATCATGCCAATTATCAC
ACCACGCAATATGTTTATGAGCATCGCATGGGCGTCAAACCTGGCGGCAATATTGCACTGCTGGCGTGTGCGGGTCCGAT
GGGCATTGGCGCTATCGATTACGCCATTAACGGTGGCATACAACCGTCACGGGTGGTGGTGGTCGATATCGACGACAAAC
GCCTGGCGCAGGTGCAGAAGCTGCTGCCGGTGGATCTGGCGGCCAGTAAAGGCATTGAGCTGGTGTATGTGAATACCAAA
GGGATGAGCGATCCGGTCCAGACGCTGCGGGCGCTGACAGGAGATGTCGGGTTCGATGACATTTTTGTTTATGCGGCGGT
GCCTGCTGTCGTTGAGATGGCTGACGAATTACTGGCGGAAGATGGCTGTCTGAACTTCTTTGCCGGGCCGACGGATAAAA
ACTTCAAAGTGCCGTTTAATTTCTACAACGTCCATTACAACAGCACGCACGTAGTCGGTACATCCGGCGGTTCAACGGAC
GACATGAAAGAGGCGATTGCGTTAAGCGCCACGGGGCAGTTGCAGCCGTCCTTTATGGTCACGCATATCGGTGGGCTGGA
TGCGGTGCCAGATACCGTGCTCAATCTGCCGGATATCCCTGGCGGTAAAAAACTCATTTATAACGGCGTGACCATGCCGC
TCACTGCCATTGCCGATTTTGCCGAAAAAGGCAAAACCGATCCGCTGTTTAAAGAGTTGGCGCGGCTGGTTGAGGAAACG
CACGGCATCTGGAATGAACAGGCCGAGAAATATCTGCTGGCACAATTTGGCGTTGATATCGGGGAGGCCGCGCAATGA

Upstream 100 bases:

>100_bases
AACCGCTGATATTGATTAATAACTATATTGGCGATCCAAAACTCGACACTTTATTTAATCAATTAACCGCCGAACATAAA
CACTGATTACAGAGGTAAAA

Downstream 100 bases:

>100_bases
TGTCCCTGGCGTGGCCATTATTTCGCGTTACGGAACAGGCAGCGTTGGCTGCCTGGCCGCAAACCGGATGTGGCGACAAA
AATAAAATTGATGGCCTGGC

Product: L-sorbose 1-phosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MKTKVAAIYGKRDVRLREFELPEITDNELLVSVISDSVCLSTWKAALLGSEHKRVPDDLENHPVITGHECAGVIVEVGKN
LTGKYKKGQRFVLQPAMGLPSGYSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYH
TTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQVQKLLPVDLAASKGIELVYVNTK
GMSDPVQTLRALTGDVGFDDIFVYAAVPAVVEMADELLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHVVGTSGGSTD
DMKEAIALSATGQLQPSFMVTHIGGLDAVPDTVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKELARLVEET
HGIWNEQAEKYLLAQFGVDIGEAAQ

Sequences:

>Translated_425_residues
MKTKVAAIYGKRDVRLREFELPEITDNELLVSVISDSVCLSTWKAALLGSEHKRVPDDLENHPVITGHECAGVIVEVGKN
LTGKYKKGQRFVLQPAMGLPSGYSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYH
TTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQVQKLLPVDLAASKGIELVYVNTK
GMSDPVQTLRALTGDVGFDDIFVYAAVPAVVEMADELLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHVVGTSGGSTD
DMKEAIALSATGQLQPSFMVTHIGGLDAVPDTVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKELARLVEET
HGIWNEQAEKYLLAQFGVDIGEAAQ
>Mature_425_residues
MKTKVAAIYGKRDVRLREFELPEITDNELLVSVISDSVCLSTWKAALLGSEHKRVPDDLENHPVITGHECAGVIVEVGKN
LTGKYKKGQRFVLQPAMGLPSGYSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYH
TTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQVQKLLPVDLAASKGIELVYVNTK
GMSDPVQTLRALTGDVGFDDIFVYAAVPAVVEMADELLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHVVGTSGGSTD
DMKEAIALSATGQLQPSFMVTHIGGLDAVPDTVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKELARLVEET
HGIWNEQAEKYLLAQFGVDIGEAAQ

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae sorE [H]

Homologues:

Organism=Escherichia coli, GI48994910, Length=425, Percent_Identity=98.8235294117647, Blast_Score=865, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 45818; Mature: 45818

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKVAAIYGKRDVRLREFELPEITDNELLVSVISDSVCLSTWKAALLGSEHKRVPDDLE
CCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCC
NHPVITGHECAGVIVEVGKNLTGKYKKGQRFVLQPAMGLPSGYSAGYSYEYFGGNATYMI
CCCEEECCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCEEEEE
IPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYHTTQYVYEHRMGVKPGGNIAL
ECCCEECEEEEECCCCCCHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHHCCCCCCCCEEE
LACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQVQKLLPVDLAASKGIELVYVNTK
EEECCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCHHHCCCCEEEEEEECC
GMSDPVQTLRALTGDVGFDDIFVYAAVPAVVEMADELLAEDGCLNFFAGPTDKNFKVPFN
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEE
FYNVHYNSTHVVGTSGGSTDDMKEAIALSATGQLQPSFMVTHIGGLDAVPDTVLNLPDIP
EEEEEECCEEEEECCCCCCHHHHHHHEEECCCCCCCCEEEEECCCCCCCCHHHHCCCCCC
GGKKLIYNGVTMPLTAIADFAEKGKTDPLFKELARLVEETHGIWNEQAEKYLLAQFGVDI
CCCEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
GEAAQ
CCCCC
>Mature Secondary Structure
MKTKVAAIYGKRDVRLREFELPEITDNELLVSVISDSVCLSTWKAALLGSEHKRVPDDLE
CCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCC
NHPVITGHECAGVIVEVGKNLTGKYKKGQRFVLQPAMGLPSGYSAGYSYEYFGGNATYMI
CCCEEECCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCEEEEE
IPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYHTTQYVYEHRMGVKPGGNIAL
ECCCEECEEEEECCCCCCHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHHCCCCCCCCEEE
LACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQVQKLLPVDLAASKGIELVYVNTK
EEECCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCHHHCCCCEEEEEEECC
GMSDPVQTLRALTGDVGFDDIFVYAAVPAVVEMADELLAEDGCLNFFAGPTDKNFKVPFN
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEE
FYNVHYNSTHVVGTSGGSTDDMKEAIALSATGQLQPSFMVTHIGGLDAVPDTVLNLPDIP
EEEEEECCEEEEECCCCCCHHHHHHHEEECCCCCCCCEEEEECCCCCCCCHHHHCCCCCC
GGKKLIYNGVTMPLTAIADFAEKGKTDPLFKELARLVEETHGIWNEQAEKYLLAQFGVDI
CCCEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
GEAAQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]