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The map label for this gene is phnO

Identifier: 157158056

GI number: 157158056

Start: 4646990

End: 4647424

Strand: Reverse

Name: phnO

Synonym: EcE24377A_4647

Alternate gene names: 157158056

Gene position: 4647424-4646990 (Counterclockwise)

Preceding gene: 157157976

Following gene: 157156446

Centisome position: 93.33

GC content: 57.7

Gene sequence:

>435_bases
ATGCCTGCTTGTGAGCTTCGCCCGGCCACGCAGTACGATACCGACGCGGTTTACGCGCTGATTTGTGAGCTAAAACAGGC
GGAGTTTGACCACCATGCGTTTCGCGTGGGCTTTAACGCCAACCTGCGCGACCCAAACATGCGCTACCATCTGGCGCTGC
TGGATGGCGAAGTTGTCGGCATGATCGGCCTGCATTTGCAGTTTCATCTGCATCATGTCAACTGGATCGGCGAAATTCAG
GAACTGGTGGTGATGCCGCAGGCGCGCGGTCTGAACGTCGGCAGTAAATTACTGGCATGGGCAGAAGAAGAAGCCCGCCA
GGCCGGGGCCGAAATGACCGAGCTTTCCACCAACGTGAAGCGCCACGACGCACACCGTTTTTACCTGCGTGAAGGCTACG
AGCAGAGCCACTTCCGCTTCACCAAGGCGCTGTAA

Upstream 100 bases:

>100_bases
CGCTATACTCCACAGGATTGCCATACGCTCAACAATGACGGCAGCCTGCGCCAGTCGGTCGACACGCTGCTGACGCTGAT
CCATCAGAAGGAGAAACACC

Downstream 100 bases:

>100_bases
CATGAGCCTGACCCTCACGCTCACCGGCACTGGCGGCGCACAGGGCGTTCCGGCATGGGGCTGCGAGTGCGCGGCCTGCG
CCAGAGCGCGGCGCTCGCCG

Product: aminoalkylphosphonic acid N-acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MPACELRPATQYDTDAVYALICELKQAEFDHHAFRVGFNANLRDPNMRYHLALLDGEVVGMIGLHLQFHLHHVNWIGEIQ
ELVVMPQARGLNVGSKLLAWAEEEARQAGAEMTELSTNVKRHDAHRFYLREGYEQSHFRFTKAL

Sequences:

>Translated_144_residues
MPACELRPATQYDTDAVYALICELKQAEFDHHAFRVGFNANLRDPNMRYHLALLDGEVVGMIGLHLQFHLHHVNWIGEIQ
ELVVMPQARGLNVGSKLLAWAEEEARQAGAEMTELSTNVKRHDAHRFYLREGYEQSHFRFTKAL
>Mature_143_residues
PACELRPATQYDTDAVYALICELKQAEFDHHAFRVGFNANLRDPNMRYHLALLDGEVVGMIGLHLQFHLHHVNWIGEIQE
LVVMPQARGLNVGSKLLAWAEEEARQAGAEMTELSTNVKRHDAHRFYLREGYEQSHFRFTKAL

Specific function: Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known

COG id: COG0454

COG function: function code KR; Histone acetyltransferase HPA2 and related acetyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain

Homologues:

Organism=Escherichia coli, GI1790531, Length=144, Percent_Identity=100, Blast_Score=301, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHNO_ECOLI (P16691)

Other databases:

- EMBL:   J05260
- EMBL:   D90227
- EMBL:   U14003
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   G35719
- RefSeq:   AP_004595.1
- RefSeq:   NP_418517.1
- ProteinModelPortal:   P16691
- SMR:   P16691
- STRING:   P16691
- EnsemblBacteria:   EBESCT00000005068
- EnsemblBacteria:   EBESCT00000015586
- GeneID:   948599
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW4054
- KEGG:   eco:b4093
- EchoBASE:   EB0718
- EcoGene:   EG10724
- eggNOG:   COG0454
- GeneTree:   EBGT00050000011821
- HOGENOM:   HBG678990
- OMA:   LPQMRGQ
- ProtClustDB:   PRK10146
- BioCyc:   EcoCyc:EG10724-MONOMER
- Genevestigator:   P16691
- InterPro:   IPR000182
- InterPro:   IPR016181
- Gene3D:   G3DSA:3.40.630.30

Pfam domain/function: PF00583 Acetyltransf_1; SSF55729 Acyl_CoA_acyltransferase

EC number: NA

Molecular weight: Translated: 16570; Mature: 16439

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS51186 GNAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPACELRPATQYDTDAVYALICELKQAEFDHHAFRVGFNANLRDPNMRYHLALLDGEVVG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEECCCEEE
MIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAEEEARQAGAEMTELSTNVK
EEEEEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCHH
RHDAHRFYLREGYEQSHFRFTKAL
HHHHHHHHHHCCCCCCCEEEECCC
>Mature Secondary Structure 
PACELRPATQYDTDAVYALICELKQAEFDHHAFRVGFNANLRDPNMRYHLALLDGEVVG
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEECCCEEE
MIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAEEEARQAGAEMTELSTNVK
EEEEEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCHH
RHDAHRFYLREGYEQSHFRFTKAL
HHHHHHHHHHCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155230; 1840580; 7610040; 9278503