Click here to switch to the map view.

The map label for this gene is chbC [H]

Identifier: 157157742

GI number: 157157742

Start: 1738259

End: 1739572

Strand: Reverse

Name: chbC [H]

Synonym: EcE24377A_1738

Alternate gene names: 157157742

Gene position: 1739572-1738259 (Counterclockwise)

Preceding gene: 157156827

Following gene: 157158588

Centisome position: 34.93

GC content: 42.77

Gene sequence:

>1314_bases
ATGGCCTCATTCGAACGTGGAATGGAACGTTTTCTTGTTCCAGTTGCTATCAAGTTAAACTCACAAAAACATGTTGCAGC
GGTGAGAGATGGATTCATTTTTACGTTTCCAATTATCATGGCAAGTTCATTAATTATATTAATTAACTTTGCCATATTAT
CGCCAGACGGTTTTATTGCCGGATTACTGCATCTGAATAGCATTTTCCCCAACCTTGAAAAAGCACAAGCTATTTTTACT
CCGGTAATGAATGGTTCTGTAAATATCATGTCAATTATGATTGCTTTCCTGGTCGCCAGGAATATGGCGATTAGCTATGA
GCAAGATGATCTTTTATGTGGATTAACGGCAATAGGAGCATTTTTTATTGTTTATACGCCATATCAGATGATAGATGGGC
AAGCATTCCTGACGACCAAATATCTCGGCGCGCAGGGGTTGTTTGTTGCTGTTATCGTTGCATTGATCACCAGTGAAATA
TTTTGTCGCTTAGCTCGAAACCCAAAAATCACCATAACGATGCCGGCAGCTGTACCGCCTGCGGTAGCGCGTTCATTTAA
AGTTTTATTGCCAATATTTTTTGTCATGGTGTTCTTTTCCGCACTTAATTATTGCCTGACACTGATATCCCCGGCAGGAC
TAAACGATCTTATTTACACATTAATCCAGACGCCGCTCAAACATATGGGAACGAATATCTTTGCGGTAATTATCCTGGGG
GCTGTGGATAATTTCCTGTGGGTGCTGGGGATCCACGGACCTAATACCACATCGGCAATTCGAGAAACCGTTTTTTCTGA
GGCTAATCTGGAGAATCTCTCCTGGGCCGCTCAACATGGCACTACCTGGGGCGCGCCATATCCGATTACCTGGACTTCTA
TTAATGATGCATTCGCCAACTGCGGCGGTTCAGGTATGACGTTGGGGTTATTGTTGGCTATTTTTATCGCTTCTAAGCGT
GCGGAATACCGTGATCTGGCAAAAATGTCATTTATCCCCGGTATTTTCAATATCAATGAACCGATAATGTTTGGCCTTCC
TATTGTACTTAACCCCATCATGATGGTGCCGTTTATTATGGTTCCCATTGTTAACTGTGCCATTGGTTACTTCTTTGTTT
CGATGGAAATTATTCCACCGGTTGCTTATGCCGTGCCCTGGACTACGCCCGGACCTTTAATTGCTTTCCTCGGAACCGGG
GGGAACTGGCTGGCTTTACTGGTTGGTTTTTTATGTTTAGGTGTGGCGACAATGATCTATTTACCTTTTGTTATTGCCGC
CAACAAAGTCAATAACATGACAACTAACGGATAA

Upstream 100 bases:

>100_bases
ACCTGAACTAACTTTTCACACATCATAAAATGGATATGGCATACATGCTTTATTGGGATGTATAAATATCCAAAACAACA
GGTATAAAAAAATGGGATTA

Downstream 100 bases:

>100_bases
TTCCATTTACCCAGGAAGGAGATTGTGATGTTTGCAGATGAAGAACTTGTTATGGAGTTACTGGTCAACGCGGGGCAGGC
ACGTTCTGACGCGATGGAAG

Product: PTS system lactose/cellobiose family IIC subunit

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Chb; PTS system N,N'-diacetylchitobiose-specific EIIC component [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MASFERGMERFLVPVAIKLNSQKHVAAVRDGFIFTFPIIMASSLIILINFAILSPDGFIAGLLHLNSIFPNLEKAQAIFT
PVMNGSVNIMSIMIAFLVARNMAISYEQDDLLCGLTAIGAFFIVYTPYQMIDGQAFLTTKYLGAQGLFVAVIVALITSEI
FCRLARNPKITITMPAAVPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQTPLKHMGTNIFAVIILG
AVDNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWGAPYPITWTSINDAFANCGGSGMTLGLLLAIFIASKR
AEYRDLAKMSFIPGIFNINEPIMFGLPIVLNPIMMVPFIMVPIVNCAIGYFFVSMEIIPPVAYAVPWTTPGPLIAFLGTG
GNWLALLVGFLCLGVATMIYLPFVIAANKVNNMTTNG

Sequences:

>Translated_437_residues
MASFERGMERFLVPVAIKLNSQKHVAAVRDGFIFTFPIIMASSLIILINFAILSPDGFIAGLLHLNSIFPNLEKAQAIFT
PVMNGSVNIMSIMIAFLVARNMAISYEQDDLLCGLTAIGAFFIVYTPYQMIDGQAFLTTKYLGAQGLFVAVIVALITSEI
FCRLARNPKITITMPAAVPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQTPLKHMGTNIFAVIILG
AVDNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWGAPYPITWTSINDAFANCGGSGMTLGLLLAIFIASKR
AEYRDLAKMSFIPGIFNINEPIMFGLPIVLNPIMMVPFIMVPIVNCAIGYFFVSMEIIPPVAYAVPWTTPGPLIAFLGTG
GNWLALLVGFLCLGVATMIYLPFVIAANKVNNMTTNG
>Mature_436_residues
ASFERGMERFLVPVAIKLNSQKHVAAVRDGFIFTFPIIMASSLIILINFAILSPDGFIAGLLHLNSIFPNLEKAQAIFTP
VMNGSVNIMSIMIAFLVARNMAISYEQDDLLCGLTAIGAFFIVYTPYQMIDGQAFLTTKYLGAQGLFVAVIVALITSEIF
CRLARNPKITITMPAAVPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQTPLKHMGTNIFAVIILGA
VDNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWGAPYPITWTSINDAFANCGGSGMTLGLLLAIFIASKRA
EYRDLAKMSFIPGIFNINEPIMFGLPIVLNPIMMVPFIMVPIVNCAIGYFFVSMEIIPPVAYAVPWTTPGPLIAFLGTGG
NWLALLVGFLCLGVATMIYLPFVIAANKVNNMTTNG

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=443, Percent_Identity=37.020316027088, Blast_Score=255, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 47520; Mature: 47389

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASFERGMERFLVPVAIKLNSQKHVAAVRDGFIFTFPIIMASSLIILINFAILSPDGFIA
CCCHHHHHHHHEEEEEEEECCCHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHCCCCHHHH
GLLHLNSIFPNLEKAQAIFTPVMNGSVNIMSIMIAFLVARNMAISYEQDDLLCGLTAIGA
HHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHH
FFIVYTPYQMIDGQAFLTTKYLGAQGLFVAVIVALITSEIFCRLARNPKITITMPAAVPP
HHHHCCCHHHHCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCH
AVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQTPLKHMGTNIFAVIILG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
AVDNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWGAPYPITWTSINDAFAN
HHHCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCEEECCCCHHHHC
CGGSGMTLGLLLAIFIASKRAEYRDLAKMSFIPGIFNINEPIMFGLPIVLNPIMMVPFIM
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHH
VPIVNCAIGYFFVSMEIIPPVAYAVPWTTPGPLIAFLGTGGNWLALLVGFLCLGVATMIY
HHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
LPFVIAANKVNNMTTNG
HHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ASFERGMERFLVPVAIKLNSQKHVAAVRDGFIFTFPIIMASSLIILINFAILSPDGFIA
CCHHHHHHHHEEEEEEEECCCHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHCCCCHHHH
GLLHLNSIFPNLEKAQAIFTPVMNGSVNIMSIMIAFLVARNMAISYEQDDLLCGLTAIGA
HHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHH
FFIVYTPYQMIDGQAFLTTKYLGAQGLFVAVIVALITSEIFCRLARNPKITITMPAAVPP
HHHHCCCHHHHCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCH
AVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQTPLKHMGTNIFAVIILG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
AVDNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWGAPYPITWTSINDAFAN
HHHCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCEEECCCCHHHHC
CGGSGMTLGLLLAIFIASKRAEYRDLAKMSFIPGIFNINEPIMFGLPIVLNPIMMVPFIM
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHH
VPIVNCAIGYFFVSMEIIPPVAYAVPWTTPGPLIAFLGTGGNWLALLVGFLCLGVATMIY
HHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
LPFVIAANKVNNMTTNG
HHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2179047; 9097039; 9278503; 2092358; 9405618; 10913117 [H]