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The map label for this gene is ugpQ [H]

Identifier: 157157691

GI number: 157157691

Start: 3904425

End: 3905168

Strand: Reverse

Name: ugpQ [H]

Synonym: EcE24377A_3926

Alternate gene names: 157157691

Gene position: 3905168-3904425 (Counterclockwise)

Preceding gene: 157158729

Following gene: 157158386

Centisome position: 78.42

GC content: 56.72

Gene sequence:

>744_bases
ATGAGTAACTGGCCTTATCCCCGCATCGTCGCTCATCGTGGCGGCGGTAAGCTGGCCCCGGAAAACACCCTGGCGGCAAT
CGACGTCGGGGCAAAATACGGTCATAAGATGATCGAATTTGACGCGAAGTTATCGAAAGATGGCGAGATCTTCCTGCTCC
ATGACGACAATCTCGAACGCACCAGCAACGGCTGGGGCGTCGCGGGTGAACTGAACTGGCAGGATTTACTGCGCGTGGAT
GCGGGCAGTTGGTACAGCAAAGCGTTTAAAGGTGAGCCGCTGCCGTTGCTTTCGCAGGTGGCGGAACGCTGTCGCGAACA
CGGGATGATGGCGAATATCGAAATCAAACCCACCACTGGCACTGGACCATTAACGGGCAAAATGGTGGCGCTGGCGGCAC
GCCAACTGTGGGCCGGTATGACGCCGCCGCTGCTGTCATCGTTTGAGATTGATGCTTTAGAAGCCGCACAATTGGCGGCA
CCGGAACTGCCGCGTGGTTTATTGCTGGATGAGTGGCGCGACGACTGGCGCGAACTGACCATGCGGCTGGGCTGCGTCTC
TCTTCATCTCAATCATAAGTTGCTCGATAAAGCGCGAGTGATGCAGTTGAAAGACGCCGGACTGCGGATTCTGGTGTATA
CCGTCAACAAACCCCAGCGCGCGGCAGAGTTGCTGCGCTGGGGCGTGGATTGCATCTGTACCGATGCGATTGATGTAATT
GGTCCGAACTTTACGGCCCAATAG

Upstream 100 bases:

>100_bases
GACTGGCGCATCAGGAGCGCCCGACGGCAGGCAGCACGCTGTGGCTGCATCTGGCGGAAAATCAGCTGCATCTTTTTGAT
GGTGAAACAGGACAACGAGT

Downstream 100 bases:

>100_bases
TTTTCAACGGAATGTCAGGCTGCGGCGTGCTGGGCTGATTCAGCATGTCGCCGTTTCTCCTCTCCGGCAGCATATGCTGC
TGATTCAACGAACTATCCGG

Product: cytoplasmic glycerophosphodiester phosphodiesterase

Products: NA

Alternate protein names: Glycerophosphodiester phosphodiesterase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVD
AGSWYSKAFKGEPLPLLSQVAERCREHGMMANIEIKPTTGTGPLTGKMVALAARQLWAGMTPPLLSSFEIDALEAAQLAA
PELPRGLLLDEWRDDWRELTMRLGCVSLHLNHKLLDKARVMQLKDAGLRILVYTVNKPQRAAELLRWGVDCICTDAIDVI
GPNFTAQ

Sequences:

>Translated_247_residues
MSNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVD
AGSWYSKAFKGEPLPLLSQVAERCREHGMMANIEIKPTTGTGPLTGKMVALAARQLWAGMTPPLLSSFEIDALEAAQLAA
PELPRGLLLDEWRDDWRELTMRLGCVSLHLNHKLLDKARVMQLKDAGLRILVYTVNKPQRAAELLRWGVDCICTDAIDVI
GPNFTAQ
>Mature_246_residues
SNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVDA
GSWYSKAFKGEPLPLLSQVAERCREHGMMANIEIKPTTGTGPLTGKMVALAARQLWAGMTPPLLSSFEIDALEAAQLAAP
ELPRGLLLDEWRDDWRELTMRLGCVSLHLNHKLLDKARVMQLKDAGLRILVYTVNKPQRAAELLRWGVDCICTDAIDVIG
PNFTAQ

Specific function: Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols [H]

COG id: COG0584

COG function: function code C; Glycerophosphoryl diester phosphodiesterase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycerophosphoryl diester phosphodiesterase family [H]

Homologues:

Organism=Homo sapiens, GI284055245, Length=89, Percent_Identity=40.4494382022472, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI284055240, Length=89, Percent_Identity=40.4494382022472, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7706617, Length=116, Percent_Identity=34.4827586206897, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI284055242, Length=89, Percent_Identity=40.4494382022472, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI21361649, Length=89, Percent_Identity=40.4494382022472, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1789858, Length=247, Percent_Identity=97.165991902834, Blast_Score=496, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004129
- InterPro:   IPR017946 [H]

Pfam domain/function: PF03009 GDPD [H]

EC number: =3.1.4.46 [H]

Molecular weight: Translated: 27379; Mature: 27248

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKLSKDGEIFLLHDDNLER
CCCCCCCEEEEECCCCCCCCCCCEEEEECCHHHCCEEEEECCCCCCCCCEEEEECCCCCC
TSNGWGVAGELNWQDLLRVDAGSWYSKAFKGEPLPLLSQVAERCREHGMMANIEIKPTTG
CCCCCCEEEECCHHHHHEECCCCHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEEECCC
TGPLTGKMVALAARQLWAGMTPPLLSSFEIDALEAAQLAAPELPRGLLLDEWRDDWRELT
CCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
MRLGCVSLHLNHKLLDKARVMQLKDAGLRILVYTVNKPQRAAELLRWGVDCICTDAIDVI
HHHHHEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCEEEHHHHHHH
GPNFTAQ
CCCCCCC
>Mature Secondary Structure 
SNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKLSKDGEIFLLHDDNLER
CCCCCCEEEEECCCCCCCCCCCEEEEECCHHHCCEEEEECCCCCCCCCEEEEECCCCCC
TSNGWGVAGELNWQDLLRVDAGSWYSKAFKGEPLPLLSQVAERCREHGMMANIEIKPTTG
CCCCCCEEEECCHHHHHEECCCCHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEEECCC
TGPLTGKMVALAARQLWAGMTPPLLSSFEIDALEAAQLAAPELPRGLLLDEWRDDWRELT
CCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
MRLGCVSLHLNHKLLDKARVMQLKDAGLRILVYTVNKPQRAAELLRWGVDCICTDAIDVI
HHHHHEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCEEEHHHHHHH
GPNFTAQ
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2541415; 1851953; 8041620; 9278503; 3062310 [H]