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The map label for this gene is mqo

Identifier: 157157678

GI number: 157157678

Start: 2491457

End: 2493103

Strand: Reverse

Name: mqo

Synonym: EcE24377A_2509

Alternate gene names: 157157678

Gene position: 2493103-2491457 (Counterclockwise)

Preceding gene: 157157028

Following gene: 157159007

Centisome position: 50.07

GC content: 54.22

Gene sequence:

>1647_bases
ATGAAAAAAGTGACTGCCATGCTCTTCTCGATGGCCGTGGGGCTTAATGCCGTTTCGATGGCGGCAAAAGCGAAAGCGTC
CGAGGAGCAGGAAACTGATGTACTGTTGATTGGCGGCGGCATTATGAGCGCCACGTTGGGGACCTATTTACGCGAGCTGG
AGCCTGAATGGTCGATGACCATGGTGGAGCGCCTGGAGGGTGTCGCGCAGGAGAGTTCGAACGGCTGGAATAACGCCGGA
ACCGGGCATTCTGCACTGATGGAACTGAACTACACCCCGCAAAACGCCGATGGCAGCATCAGTATTGAAAAAGCAGTCGC
CATTAACGAAGCATTTCAGATTTCCCGCCAGTTCTGGGCGCACCAGGTTGAGCGCGGCGTGCTGCGTACTCCGCGTTCAT
TTATCAATACCGTTCCGCATATGAGCTTTGTCTGGGGCGAGGATAACGTTAATTTCCTGCGCGCCCGTTACGCCGCGTTG
CAACAAAGCTCGCTGTTTCGCGGTATGCGTTACTCTGAAGATCACGCGCAGATCAAAGAGTGGGCACCGTTAGTGATGGA
AGGGCGCGATCCGCAACAGAAAGTGGCAGCCACGCGTACGGAAATTGGTACCGATGTGAACTACGGCGAGATCACCCGCC
AGTTAATTGCTTCCTTGCAGAAGAAATCTAACTTCTCGCTGCAACTCAGCAGCGAAGTCCGCGCCCTAAAGCGTAATGAC
GATAACACCTGGACCGTTACCGTTGCCGATCTGAAAAACGGCACTGCACAGAACATCCGCGCCAAATTTGTCTTTATCGG
CGCGGGCGGTGCGGCGCTGAAGCTATTACAGGAATCGGGGATTCCGGAAGCGAAAGACTACGCCGGTTTCCCGGTGGGCG
GACAGTTCCTTGTTTCGGAAAACCCGGACGTGGTTAATCACCATCTGGCGAAGGTTTACGGTAAAGCATCCGTTGGCGCA
CCACCGATGTCGGTTCCGCATATCGATACCCGCGTTCTGGACGGTAAACGCGTAGTGCTGTTTGGGCCATTTGCCACCTT
CTCAACCAAATTCCTCAAAAACGGTTCATTGTGGGATCTGATGAGTTCCACCACCACCTCTAACGTGATGCCGATGATGC
ACGTCGGGCTGGATAATTTCGATCTGGTGAAATATCTGGTGAGTCAGGTGATGTTGAGTGAAGAGGATCGTTTTGAAGCG
TTGAAAGAGTACTATCCGCAGGCAAAAAAAGAGGACTGGCGTTTGTGGCAAGCGGGGCAGCGCGTGCAGATTATCAAGCG
TGATGCCGAGAAAGGTGGCGTACTGCGTCTGGGTACTGAAGTGGTCAGTGACCAGCAAGGGACCATTGCCGCGCTGCTGG
GGGCATCGCCAGGGGCGTCAACCGCCGCGCCGATTATGTTGGATCTGCTGGAAAAAGTATTTGGCGATCGCGTTTCCAGC
CCGCAATGGCAGGCTACGTTGAAAGCGATCGTTCCGTCTTATGGACGCAAGCTGAACGGTGATGTAGCGGCAACAGAACG
CGAGTTGCAGTACACCAGCGAAGTGCTGGGGCTGAAATACGACAAGCCGCAGGCAGCAGATAGTACGCCAAAACCGCAGT
TGAAACCGCAACCCGTTCAAAAAGAAGTGGCGGATATTGCGTTGTAA

Upstream 100 bases:

>100_bases
AATTTATAAACATTATTTAAATGTTGTTACTTAAGTGTTACCGTTGATGCCGCGCAAATCTCACCTGCAATAAAGCGACT
AAAAGTAAGGCATTAACAAG

Downstream 100 bases:

>100_bases
TGATGTGCCACATCCGGCATGGTATGCCGGATGTGGCGTATGCTGATAAGACGCGCCAGCGTCGCATCAGGCACCGGCTC
GGGCGTTAGATGTCGGATGC

Product: malate:quinone oxidoreductase

Products: NA

Alternate protein names: MQO; Malate dehydrogenase [quinone]

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAG
TGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAAL
QQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRND
DNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGA
PPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEA
LKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLDLLEKVFGDRVSS
PQWQATLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL

Sequences:

>Translated_548_residues
MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAG
TGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAAL
QQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRND
DNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGA
PPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEA
LKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLDLLEKVFGDRVSS
PQWQATLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL
>Mature_548_residues
MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAG
TGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAAL
QQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRND
DNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGA
PPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEA
LKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLDLLEKVFGDRVSS
PQWQATLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family

Homologues:

Organism=Escherichia coli, GI1788539, Length=548, Percent_Identity=99.6350364963504, Blast_Score=1125, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MQO_ECO24 (A7ZP32)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001463561.1
- ProteinModelPortal:   A7ZP32
- STRING:   A7ZP32
- EnsemblBacteria:   EBESCT00000018971
- GeneID:   5588173
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_2509
- eggNOG:   COG0579
- GeneTree:   EBGT00050000010864
- HOGENOM:   HBG289663
- OMA:   NALKEYF
- ProtClustDB:   PRK05257
- BioCyc:   ECOL331111:ECE24377A_2509-MONOMER
- HAMAP:   MF_00212
- InterPro:   IPR006231
- TIGRFAMs:   TIGR01320

Pfam domain/function: PF06039 Mqo

EC number: =1.1.5.4

Molecular weight: Translated: 60245; Mature: 60245

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMT
CHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHH
MVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWA
HHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
HQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAALQQSSLFRGMRYSEDHAQIKE
HHHHHHHHCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
WAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRND
CCCCEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCC
DNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSE
CCEEEEEEEECCCCCCCCEEEEEEEEECCHHHHHHHHHCCCCCCHHCCCCCCCCEEEECC
NPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDL
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCEEEEEECHHHHHHHHHCCCCHHHH
MSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEALKEYYPQAKKEDWRLWQAGQ
HHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHCCC
RVQIIKRDAEKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLDLLEKVFGDRVSS
EEEEEHHHCCCCCEEEECHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCC
PQWQATLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQ
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
KEVADIAL
HHHHHHCC
>Mature Secondary Structure
MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMT
CHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHH
MVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWA
HHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
HQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAALQQSSLFRGMRYSEDHAQIKE
HHHHHHHHCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
WAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRND
CCCCEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCC
DNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSE
CCEEEEEEEECCCCCCCCEEEEEEEEECCHHHHHHHHHCCCCCCHHCCCCCCCCEEEECC
NPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDL
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCEEEEEECHHHHHHHHHCCCCHHHH
MSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEALKEYYPQAKKEDWRLWQAGQ
HHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHCCC
RVQIIKRDAEKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLDLLEKVFGDRVSS
EEEEEHHHCCCCCEEEECHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCC
PQWQATLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQ
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
KEVADIAL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA