Click here to switch to the map view.

The map label for this gene is glgP

Identifier: 157157318

GI number: 157157318

Start: 3881974

End: 3884421

Strand: Reverse

Name: glgP

Synonym: EcE24377A_3907

Alternate gene names: 157157318

Gene position: 3884421-3881974 (Counterclockwise)

Preceding gene: 157158992

Following gene: 157157817

Centisome position: 78.01

GC content: 50.94

Gene sequence:

>2448_bases
ATGAATGCTCCGTTTACATATTCATCGCCCACGCTTAGCGTAGAAGCTCTTAAGCACTCTATCGCTTACAAGCTGATGTT
TACGATTGGAAAGGACCCGGTCGTCGCCAATAAACATGAATGGCTGAACGCAACGTTATTTGCTGTGCGCGATCGTCTCG
TGGAGCGCTGGTTACGTTCAAACCGTGCCCAGTTGTCGCAAGAAACTCGTCAGGTTTACTACCTGTCGATGGAGTTTTTG
ATTGGCCGTACGCTCTCCAACGCCATGTTGTCGCTAGGAATTTACGAAGATGTACAGGGCGCACTGGAAGCGATGGGGTT
AAATCTCGAAGAGCTGATTGATGAAGAAAATGATCCGGGCCTCGGTAACGGTGGCCTGGGACGTCTGGCGGCTTGCTTCC
TTGATTCTCTGGCGACGTTAGGGTTGCCGGGGCGCGGTTACGGCATCCGCTATGACTACGGTATGTTCAAGCAGAACATC
GTTAACGGTAGCCAGAAAGAGTCGCCAGACTACTGGCTGGAATACGGTAACCCGTGGGAATTCAAACGCCACAACACGCG
CTATAAAGTCCGTTTTGGTGGTCGCATTCAGCAGGAAGGTAAAAAAACGCGCTGGATTGAAACCGAAGAGATTCTGGGAG
TCGCTTACGATCAGATAATCCCTGGTTACGATACCGACGCGACCAACACGTTGCGTTTGTGGAGTGCGCAAGCCAGTAGC
GAAATTAACCTCGGTAAATTCAACCAGGGTGACTACTTCGCGGCAGTGGAAGATAAAAACCACTCCGAGAACGTATCTCG
CGTACTGTATCCGGATGACTCCACCTACTCCGGGCGTGAGCTGCGCCTGCGTCAGGAATACTTCCTGGTTTCCTCGACCA
TTCAGGACATTTTAAGCCGCCATTATCAGTTGCATAAAACCTACGATAACCTGGCGGATAAAATCGCGATTCATCTCAAT
GATACCCATCCGGTACTGTCGATTCCTGAGATGATGCGTCTGCTGATCGATGAGCACCAATTTAGCTGGGACGACGCGTT
TGAGGTGTGTTGTCAGGTCTTCTCCTACACTAACCACACGCTGATGAGCGAGGCGCTGGAAACCTGGCCGGTTGATATGC
TGGGTAAAATTCTGCCGCGTCACCTGCAGATCATCTTTGAAATCAACGACTATTTCCTGAAAACCTTGCAGGAACAGTAT
CCGAACGATACCGATCTGCTGGGACGGGCGTCGATCATTGATGAATCCAACGGTCGTCGTGTGCGTATGGCCTGGCTGGC
GGTTGTTGTGAGCCACAAAGTTAACGGTGTATCGGAACTGCACTCTAATCTGATGGTGCAATCGTTGTTTGCCGACTTTG
CGAAAATCTTCCCGGGTCGTTTCACCAACGTCACCAACGGTGTGACGCCGCGTCGCTGGCTAGCGGTAGCGAACCCATCG
CTTTCAGCCGTGCTGGACGAACACCTGGGCCGTAACTGGCGCACCGACCTTAGCCTGCTTAATGAGCTGCAACAACACTG
TGATTTCCCAATGGTTAATCACGCTGTGCATCAGGCGAAGCTGGAGAACAAAAAGCGTCTGGCAGAGTATATCGCCCAGC
AGCTGAATGTGGTGGTGAATCCAAAGGCGTTGTTCGATGTACAAATCAAACGTATTCACGAATACAAACGTCAATTGATG
AATGTGTTGCATGTGATTACCCGCTATAACCGCATCAAGGCCGACCCGGATGCGAAGTGGGTACCGCGCGTGAATATTTT
TGGCGGTAAGGCGGCTTCGGCCTATTACATGGCGAAGCACATTATTCATTTGATCAATGACGTAGCGAAAGTGATCAACA
ACGATCCGCAGATTGGCGACAAGCTGAAAGTCGTGTTCATCCCGAACTACAGCGTTAGCCTGGCGCAGTTGATCATTCCG
GCGGCCGATCTGTCTGAACAGATTTCGCTGGCGGGGACGGAAGCTTCCGGCACCAGTAACATGAAGTTTGCGCTTAACGG
TGCGCTGACTATCGGTACGTTGGACGGTGCGAATGTCGAGATGCTGGATCATGTCGGTGCTGACAATATCTTTATCTTTG
GTAACACTGCGGAAGAAGTGGAAGAACTGCGTCGTCAGGGCTACAAACCGCGTGAATACTACGAGAAAGATGAGGAGCTG
CATCAGGTGCTGACGCAAATCGGCAGCGGTGTATTCAGTCCGGAAGATCCGGGTCGCTATCGCGATCTGGTTGATTCGCT
GATCAACTTCGGCGATCACTATCAGGTTCTGGCGGATTATCGCAGCTATGTCGATTGTCAGGATAAAGTCGACGAACTCT
ACGAGCTTCAGGAAGAGTGGACCGCAAAAGCGATGCTGAACATTGCCAATATGGGCTACTTCTCTTCTGACCGTACTATC
AAAGAGTACGCCGATCATATCTGGCATATTGATCCGGTGAGATTGTAA

Upstream 100 bases:

>100_bases
GCAACGTCAGGCTATGGCAATGGATTTTAGCTGGCAGGTCGCGGCGAAGTCGTACCGTGAGCTTTACTATCGCTTGAAAT
AGTTTTCAGGAAACGCCTAT

Downstream 100 bases:

>100_bases
TTTCACTAATAAATAGAACGGGGCCAAAGGGTCCCGTTTTTTTCGCCATCATTTCGGAAAAGTGTCCAGAAGGGGCAAGG
GGACTCGGGGAGTATAATTT

Product: glycogen phosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 815; Mature: 815

Protein sequence:

>815_residues
MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNATLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFL
IGRTLSNAMLSLGIYEDVQGALEAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
VNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQIIPGYDTDATNTLRLWSAQASS
EINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLN
DTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYFLKTLQEQY
PNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLFADFAKIFPGRFTNVTNGVTPRRWLAVANPS
LSAVLDEHLGRNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLM
NVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIP
AADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEMLDHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEEL
HQVLTQIGSGVFSPEDPGRYRDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYELQEEWTAKAMLNIANMGYFSSDRTI
KEYADHIWHIDPVRL

Sequences:

>Translated_815_residues
MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNATLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFL
IGRTLSNAMLSLGIYEDVQGALEAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
VNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQIIPGYDTDATNTLRLWSAQASS
EINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLN
DTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYFLKTLQEQY
PNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLFADFAKIFPGRFTNVTNGVTPRRWLAVANPS
LSAVLDEHLGRNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLM
NVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIP
AADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEMLDHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEEL
HQVLTQIGSGVFSPEDPGRYRDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYELQEEWTAKAMLNIANMGYFSSDRTI
KEYADHIWHIDPVRL
>Mature_815_residues
MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNATLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFL
IGRTLSNAMLSLGIYEDVQGALEAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
VNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQIIPGYDTDATNTLRLWSAQASS
EINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLN
DTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYFLKTLQEQY
PNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLFADFAKIFPGRFTNVTNGVTPRRWLAVANPS
LSAVLDEHLGRNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLM
NVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIP
AADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEMLDHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEEL
HQVLTQIGSGVFSPEDPGRYRDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYELQEEWTAKAMLNIANMGYFSSDRTI
KEYADHIWHIDPVRL

Specific function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties

COG id: COG0058

COG function: function code G; Glucan phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycogen phosphorylase family

Homologues:

Organism=Homo sapiens, GI71037379, Length=812, Percent_Identity=50, Blast_Score=800, Evalue=0.0,
Organism=Homo sapiens, GI21361370, Length=810, Percent_Identity=50.1234567901235, Blast_Score=799, Evalue=0.0,
Organism=Homo sapiens, GI5032009, Length=810, Percent_Identity=49.0123456790123, Blast_Score=795, Evalue=0.0,
Organism=Homo sapiens, GI255653002, Length=812, Percent_Identity=48.5221674876847, Blast_Score=754, Evalue=0.0,
Organism=Homo sapiens, GI257900462, Length=665, Percent_Identity=49.0225563909774, Blast_Score=691, Evalue=0.0,
Organism=Escherichia coli, GI2367228, Length=815, Percent_Identity=100, Blast_Score=1696, Evalue=0.0,
Organism=Escherichia coli, GI48994936, Length=766, Percent_Identity=47.7806788511749, Blast_Score=731, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17564550, Length=810, Percent_Identity=50.2469135802469, Blast_Score=828, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32566204, Length=810, Percent_Identity=50.2469135802469, Blast_Score=827, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325418, Length=811, Percent_Identity=47.2256473489519, Blast_Score=725, Evalue=0.0,
Organism=Drosophila melanogaster, GI78706832, Length=809, Percent_Identity=49.4437577255871, Blast_Score=815, Evalue=0.0,
Organism=Drosophila melanogaster, GI24581010, Length=809, Percent_Identity=49.4437577255871, Blast_Score=815, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHSG_ECOLI (P0AC86)

Other databases:

- EMBL:   X16931
- EMBL:   J03966
- EMBL:   U18997
- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   M22368
- EMBL:   D00425
- EMBL:   J02616
- PIR:   G65138
- RefSeq:   AP_004363.1
- RefSeq:   NP_417886.1
- ProteinModelPortal:   P0AC86
- SMR:   P0AC86
- DIP:   DIP-47899N
- MINT:   MINT-1307808
- STRING:   P0AC86
- EnsemblBacteria:   EBESCT00000003797
- EnsemblBacteria:   EBESCT00000003798
- EnsemblBacteria:   EBESCT00000003799
- EnsemblBacteria:   EBESCT00000015041
- GeneID:   947931
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW3391
- KEGG:   eco:b3428
- EchoBASE:   EB0375
- EcoGene:   EG10380
- eggNOG:   COG0058
- GeneTree:   EBGT00050000009895
- HOGENOM:   HBG444050
- OMA:   DEHIGRT
- ProtClustDB:   PRK14986
- BioCyc:   EcoCyc:GLYCOPHOSPHORYL-MONOMER
- BioCyc:   MetaCyc:GLYCOPHOSPHORYL-MONOMER
- Genevestigator:   P0AC86
- GO:   GO:0005737
- InterPro:   IPR011833
- InterPro:   IPR000811
- PANTHER:   PTHR11468
- PIRSF:   PIRSF000460
- TIGRFAMs:   TIGR02093

Pfam domain/function: PF00343 Phosphorylase

EC number: =2.4.1.1

Molecular weight: Translated: 93174; Mature: 93174

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00102 PHOSPHORYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNATLFAVRDRLVERWLRS
CCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NRAQLSQETRQVYYLSMEFLIGRTLSNAMLSLGIYEDVQGALEAMGLNLEELIDEENDPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHCCCCCCC
LGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNIVNGSQKESPDYWLEYGNPWE
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHCCCCCCCCCCCEEECCCCCC
FKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQIIPGYDTDATNTLRLWSAQASS
CCCCCCEEEEEECCEEHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC
EINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSSTIQDILSR
CCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
HYQLHKTYDNLADKIAIHLNDTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHT
HHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHH
LMSEALETWPVDMLGKILPRHLQIIFEINDYFLKTLQEQYPNDTDLLGRASIIDESNGRR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHEECCCCCE
VRMAWLAVVVSHKVNGVSELHSNLMVQSLFADFAKIFPGRFTNVTNGVTPRRWLAVANPS
EHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEECCCC
LSAVLDEHLGRNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVVVN
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
PKALFDVQIKRIHEYKRQLMNVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHH
IIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSN
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHCHHHHHHHHHCCCCCCCCCCC
MKFALNGALTIGTLDGANVEMLDHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEEL
EEEEEECEEEEEECCCCCHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCCHHHHCCHHHH
HQVLTQIGSGVFSPEDPGRYRDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYELQEEW
HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TAKAMLNIANMGYFSSDRTIKEYADHIWHIDPVRL
HHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNATLFAVRDRLVERWLRS
CCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NRAQLSQETRQVYYLSMEFLIGRTLSNAMLSLGIYEDVQGALEAMGLNLEELIDEENDPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHCCCCCCC
LGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNIVNGSQKESPDYWLEYGNPWE
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHCCCCCCCCCCCEEECCCCCC
FKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQIIPGYDTDATNTLRLWSAQASS
CCCCCCEEEEEECCEEHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC
EINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSSTIQDILSR
CCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
HYQLHKTYDNLADKIAIHLNDTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHT
HHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHH
LMSEALETWPVDMLGKILPRHLQIIFEINDYFLKTLQEQYPNDTDLLGRASIIDESNGRR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHEECCCCCE
VRMAWLAVVVSHKVNGVSELHSNLMVQSLFADFAKIFPGRFTNVTNGVTPRRWLAVANPS
EHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEECCCC
LSAVLDEHLGRNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVVVN
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
PKALFDVQIKRIHEYKRQLMNVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHH
IIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSN
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHCHHHHHHHHHCCCCCCCCCCC
MKFALNGALTIGTLDGANVEMLDHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEEL
EEEEEECEEEEEECCCCCHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCCHHHHCCHHHH
HQVLTQIGSGVFSPEDPGRYRDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYELQEEW
HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TAKAMLNIANMGYFSSDRTIKEYADHIWHIDPVRL
HHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2645169; 3047129; 9278503; 2975249; 3097003