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The map label for this gene is yagR [H]

Identifier: 157156885

GI number: 157156885

Start: 322257

End: 324455

Strand: Reverse

Name: yagR [H]

Synonym: EcE24377A_0295

Alternate gene names: 157156885

Gene position: 324455-322257 (Counterclockwise)

Preceding gene: 157156073

Following gene: 157154740

Centisome position: 6.52

GC content: 59.35

Gene sequence:

>2199_bases
ATGAAATTTGATAAACCCGCAGGGGAAAACCCGATCGATCAGCTGAAGGTTGTCGGTCGTCCCCATGACCGCATCGACGG
ACCGCTGAAAACTACCGGCACGGCACGCTACGCCTACGAATGGCATGAAGAAGCCCCCAACGCCGCCTATGGCTATATCG
TCGGTTCCGCCATTGCCAAAGGACGCCTCACCGCCCTTGATACGGACGCCGCGCAAAAAGCGCCGGGCGTACTGGCTGTC
ATTACCGCCAGTAACGCCGGGGCACTCGGCAAAGGCGACAAAAACACCGCCAGACTGTTAGGCGGCCCCACTATTGAGCA
CTATCATCAGGCCATTGCGCTGGTAGTGGCCGAGACCTTCGAACAGGCGCGAGCGGCGGCCTCGCTGGTGCAGGCACACT
ATCGCCGTAATAAAGGAGCTTACTCCCTGGCGGACGAAAAACAGGCCGTCAATCAGCCGCCGGAAGACACGCCCGACAAA
AACGTCGGTGACTTTGACGGGGCTTTCACCTCCGCTGCGGTGAAGATTGATGCTACCTACACGACCCCGGACCAGAGCCA
TATGGCGATGGAGCCGCATGCCTCGATGGCCGTCTGGGATGGAAATAAGCTTACCCTCTGGACCTCAAATCAGATGATTG
ACTGGTGCCGCACCGATCTGGCAAAAACGCTGAAAGTTCCCGTGGAGAATGTGCGTATTATCTCCCCGTATATCGGCGGA
GGGTTTGGCGGCAAGCTGTTCCTGAGAAGCGATGCGCTGCTGGCGGCCCTCGCCGCCCGAGCGGTGAAACGTCCGGTTAA
AGTGATGCTCCCCCGCCCCTCTATTCCCAATAACACCACGCACCGCCCCGCCACCCTTCAGCACTTGCGTATCGGTGCCG
ACCAGAGCGGGAAAATCACCGCTATCTCACATGAAAGCTGGTCTGGAAACCTGCCCGGCGGCACGCCGGAAACGGCGGTA
CAGCAAAGCGAATTACTCTACGCCGGGGCGAATCGTCATACCGGCCTGCGGCTCGCCACGCTTGATTTGCCGGAAGGGAA
CGCCATGCGTGCGCCCGGCGAAGCCCCCGGTCTGATGGCGCTCGAAATCGCGATCGACGAACTGGCGGAAAAAGCGGGCA
TCGATCCCGTCGAGTTTCGCATCCTGAATGACACTCAGGTTGACCCCGCCGACCCGACGCGCTGCTTCTCTCGCCGTCAG
CTTATCGAGTGCTTGCGCACCGGAGCGGATAAATTTGGCTGGAAGCAGCGCAACGCCACACCCGGACAGGTGCGCGACGG
GGAGTGGCTAGTCGGCCACGGTGTTGCGGCGGGCTTTCGCAATAATCTGCTGGAAAAATCGGGTGCTCGGGTTCACCTCG
AACAAAACGGCACCGTTACCGTAGAAACGGACATGACCGACATTGGCACCGGCAGCTACACCATTCTGGCCCAGACGGCA
GCGGAAATGCTTGGCGTACCGCTGGAGCAGGTTGCGGTTCACCTCGGCGATTCCAGTTTCCCGGTTTCTGCGGGTTCTGG
TGGACAATGGGGCGCGAATACCTCCACCTCCGGCGTTTACGCCGCCTGTATGAAGCTTCGCGAAATGATTGCCTCGGCAG
TCGGGTTTGATCCTGAGCAGTCGCAGTTTGCCGACGGCAAGATTACCAACGGTACCCGAAGCGCCACGCTACATGAAGCC
ACCGCAGGCGGCAGACTGACAGCGGAAGAGAGCATTGAATTCGGAACACTGAGCAAAGAGTACCAGCAGTCGACCTTTGC
CGGGCATTTTGTGGAGGTCGGCGTGCATAGCGCGACGGGAGAAGTTCGGGTCCGGCGTATGCTCGCTGTGTGTGCTGCAG
GACGCATCCTGAATCCGAAAACTGCGCGCAGCCAGGTCATTGGCGCAATGACTATGGGCATGGGTGCGGCACTGATGGAG
GAGCTGGCGGTGGATGACCGTTTGGGCTACTTCGTTAATCACGATATGGCGGGGTATGAGGTGCCGGTCCATGCGGATAT
CCCAAAACAGGAGGTGATTTTCCTGGATGATACCGACCCCATATCCTCCCCGATGAAGGCCAAAGGTGTCGGTGAGCTGG
GCCTGTGCGGCGTGAGCGCGGCTATCGCCAACGCGGTGTATAACGCCACCGGTATTCGGGTACGGGATTATCCCATCACT
CTGGATAAGCTGCTCGATAAGCTGCCGGATGTAGTTTAA

Upstream 100 bases:

>100_bases
CGCTGTTCGCCAGCGCCCATCCCACCGCTGAAAATACCTTTAAACTCCTGTTGGCGAAGCGAACGCTTGCCTCCGTACTG
GCTGAAGCGAGGGCACAGGC

Downstream 100 bases:

>100_bases
GGAGAAACAATGTCATACCCGCTTTTTGATAAAGACGAACACTGGCATAAGCCAGAGCAGGCGTTTCTCACCGATGACCA
CCGTACCATTCTGCGCTTCG

Product: xanthine dehydrogenase family protein, molybdopterin-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 732; Mature: 732

Protein sequence:

>732_residues
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEEAPNAAYGYIVGSAIAKGRLTALDTDAAQKAPGVLAV
ITASNAGALGKGDKNTARLLGGPTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVNQPPEDTPDK
NVGDFDGAFTSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIPNNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAV
QQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQVDPADPTRCFSRRQ
LIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEQNGTVTVETDMTDIGTGSYTILAQTA
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACMKLREMIASAVGFDPEQSQFADGKITNGTRSATLHEA
TAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAGRILNPKTARSQVIGAMTMGMGAALME
ELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
LDKLLDKLPDVV

Sequences:

>Translated_732_residues
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEEAPNAAYGYIVGSAIAKGRLTALDTDAAQKAPGVLAV
ITASNAGALGKGDKNTARLLGGPTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVNQPPEDTPDK
NVGDFDGAFTSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIPNNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAV
QQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQVDPADPTRCFSRRQ
LIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEQNGTVTVETDMTDIGTGSYTILAQTA
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACMKLREMIASAVGFDPEQSQFADGKITNGTRSATLHEA
TAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAGRILNPKTARSQVIGAMTMGMGAALME
ELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
LDKLLDKLPDVV
>Mature_732_residues
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEEAPNAAYGYIVGSAIAKGRLTALDTDAAQKAPGVLAV
ITASNAGALGKGDKNTARLLGGPTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVNQPPEDTPDK
NVGDFDGAFTSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIPNNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAV
QQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQVDPADPTRCFSRRQ
LIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEQNGTVTVETDMTDIGTGSYTILAQTA
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACMKLREMIASAVGFDPEQSQFADGKITNGTRSATLHEA
TAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAGRILNPKTARSQVIGAMTMGMGAALME
ELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
LDKLLDKLPDVV

Specific function: Unknown

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=747, Percent_Identity=25.5689424364123, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI71773480, Length=741, Percent_Identity=24.5614035087719, Blast_Score=135, Evalue=2e-31,
Organism=Escherichia coli, GI1786478, Length=732, Percent_Identity=100, Blast_Score=1508, Evalue=0.0,
Organism=Escherichia coli, GI1789230, Length=763, Percent_Identity=29.0956749672346, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1789246, Length=807, Percent_Identity=25.6505576208178, Blast_Score=191, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17540638, Length=724, Percent_Identity=25.5524861878453, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32566215, Length=568, Percent_Identity=23.4154929577465, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17539860, Length=731, Percent_Identity=21.3406292749658, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24647199, Length=719, Percent_Identity=23.7830319888734, Blast_Score=127, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24647195, Length=743, Percent_Identity=24.4952893674293, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24647197, Length=734, Percent_Identity=24.5231607629428, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24647193, Length=727, Percent_Identity=24.3466299862448, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI17737937, Length=732, Percent_Identity=24.7267759562842, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24647201, Length=724, Percent_Identity=24.4475138121547, Blast_Score=112, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 78089; Mature: 78089

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEEAPNAAYGYIVGSAIAK
CCCCCCCCCCHHHHHEECCCCCHHCCCCCCCCCCEEEEEEHHHCCCCCEEHHHHHHHHHC
GRLTALDTDAAQKAPGVLAVITASNAGALGKGDKNTARLLGGPTIEHYHQAIALVVAETF
CCEEEECCCHHHHCCCEEEEEEECCCCCCCCCCCCCHHEECCCCHHHHHHHHHHHHHHHH
EQARAAASLVQAHYRRNKGAYSLADEKQAVNQPPEDTPDKNVGDFDGAFTSAAVKIDATY
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEEE
TTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
CCCCCCCEEECCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCC
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIPNNTTHRPATLQHLRIGADQSGKIT
CCCCEEEEECHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHEEECCCCCCCEE
AISHESWSGNLPGGTPETAVQQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMA
EEECCCCCCCCCCCCCHHHHHHHHEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCEEE
LEIAIDELAEKAGIDPVEFRILNDTQVDPADPTRCFSRRQLIECLRTGADKFGWKQRNAT
EHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCCC
PGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEQNGTVTVETDMTDIGTGSYTILAQTA
CCCCCCCCEEEECCHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCEEEHHHHH
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACMKLREMIASAVGFDPEQ
HHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
SQFADGKITNGTRSATLHEATAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATG
CCCCCCCCCCCCCCCEEEECCCCCEEEHHCCCCCCCCCHHHHHHHHCCEEEEEECCCCCH
EVRVRRMLAVCAAGRILNPKTARSQVIGAMTMGMGAALMEELAVDDRLGYFVNHDMAGYE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCE
VPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
EEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCC
LDKLLDKLPDVV
HHHHHHHCCCCC
>Mature Secondary Structure
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEEAPNAAYGYIVGSAIAK
CCCCCCCCCCHHHHHEECCCCCHHCCCCCCCCCCEEEEEEHHHCCCCCEEHHHHHHHHHC
GRLTALDTDAAQKAPGVLAVITASNAGALGKGDKNTARLLGGPTIEHYHQAIALVVAETF
CCEEEECCCHHHHCCCEEEEEEECCCCCCCCCCCCCHHEECCCCHHHHHHHHHHHHHHHH
EQARAAASLVQAHYRRNKGAYSLADEKQAVNQPPEDTPDKNVGDFDGAFTSAAVKIDATY
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEEE
TTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
CCCCCCCEEECCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCC
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIPNNTTHRPATLQHLRIGADQSGKIT
CCCCEEEEECHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHEEECCCCCCCEE
AISHESWSGNLPGGTPETAVQQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMA
EEECCCCCCCCCCCCCHHHHHHHHEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCEEE
LEIAIDELAEKAGIDPVEFRILNDTQVDPADPTRCFSRRQLIECLRTGADKFGWKQRNAT
EHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCCC
PGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEQNGTVTVETDMTDIGTGSYTILAQTA
CCCCCCCCEEEECCHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCEEEHHHHH
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACMKLREMIASAVGFDPEQ
HHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
SQFADGKITNGTRSATLHEATAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATG
CCCCCCCCCCCCCCCEEEECCCCCEEEHHCCCCCCCCCHHHHHHHHCCEEEEEECCCCCH
EVRVRRMLAVCAAGRILNPKTARSQVIGAMTMGMGAALMEELAVDDRLGYFVNHDMAGYE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCE
VPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
EEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCC
LDKLLDKLPDVV
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]