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The map label for this gene is tdcD [H]

Identifier: 157156881

GI number: 157156881

Start: 3597329

End: 3598537

Strand: Reverse

Name: tdcD [H]

Synonym: EcE24377A_3589

Alternate gene names: 157156881

Gene position: 3598537-3597329 (Counterclockwise)

Preceding gene: 157154888

Following gene: 157155072

Centisome position: 72.27

GC content: 48.06

Gene sequence:

>1209_bases
ATGAATGAATTTCCGGTTGTTTTGGTTATTAACTGTGGTTCGTCTTCGATTAAGTTTTCCGTACTCGATGCCAGCGACTG
TGAAGTATTAATGTCAGGTATTGCCGACGGTATTAACTCGGAAAATGCATTCTTATCCGTAAATGGGGGAGAGCCAGCAC
CGCTGGCTCACCACAGCTACGAAGGTGCATTGAAGGCAATTGCATTTGAACTGGAAAAACGGAATTTAAATGACAGTGTG
GCCTTAATTGGCCACCGCATCGCTCACGGCGGCAGTATTTTTACCGAGTCCGCCATTATTACCGATGAAGTCATTGATAA
TATCCGTCGCGTTTCTCCACTGGCACCCCTGCATAATTACGCCAATTTAAGTGGTATTGAATCGGCGCAGCAATTATTTC
CGGGCGTAACTCAGGTGGCGGTATTTGATACCAGTTTCCACCAGACGATGGCTCCGAAAGCTTATTTATACGGCCTGCCG
TGGAAATATTATGAAGAGTTAGGTGTACGCCGTTATGGTTTCCACGGCACGTCGCACCGCTATGTTTCCCAGCGCGCACA
TTCGCTGCTGAATCTGGCGGAAGATGACTCCGGCCTGGTTGTGGCGCATCTTGGCAATGGCGCGTCAATCTGCGCGGTTC
GCAACGGTCAGAGTGTTGATACTTCAATGGGAATGACGCCGCTGGAAGGCTTGATGATGGGTACCCGCAGTGGCGATGTC
GACTTTGGTGCGATGTCCTGGGTCGCCAGCCAAACCAACCAGAGCCTGGGTGACCTGGAACGCGTAGTGAATAAAGAGTC
GGGATTATTAGGTATTTCCGGTCTTTCTTCGGATTTACGTGTTCTGGAAAAAGCCTGGCATGAAGGTCACGAACGCGCGC
AACTGGCAATTAAAACCTTTGTTCACCGAATTGCCCGTCATATTGCCGGACACGCAGCTTCATTACGTCGCCTGGATGGA
ATTATATTCACCGGTGGAATAGGAGAGAATTCAAGCTTAATTCGTCGTCTGGTCATGGAACATTTGGCTGTATTAGGCGT
AGAGATTGATACAGAAATGAATAATCGCTCTAACTCCTGTGGTGAGCGAATTGTTTCCAGTGAAAATGCGCGTGTCATTT
GCGCTGTTATTCCGACTAACGAAGAAAAAATGATTGCTTTGGATGCCATTCATTTAGGCAAAGTTAACGCGCCCGCAGAA
TTTGCATAA

Upstream 100 bases:

>100_bases
GGTCGTCTGGATAACGTGTTTGTTACCGTGATTGGTCTGCTGACCATCCTGAACATCGTATACAAACTGTTTTAATCCGT
AACTCAGGATGAGAAAAGAG

Downstream 100 bases:

>100_bases
TTTAGTTGAAGTATTGTAGAGAGATTATTTTTCATGAAGGTAGATATTGATACCAGCGATAAGCTGTACGCCGACGCATG
GCTTGGCTTTAAAGGTACGG

Product: propionate/acetate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSV
ALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPKAYLYGLP
WKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDV
DFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDG
IIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAE
FA

Sequences:

>Translated_402_residues
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSV
ALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPKAYLYGLP
WKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDV
DFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDG
IIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAE
FA
>Mature_402_residues
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSV
ALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPKAYLYGLP
WKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDV
DFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDG
IIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAE
FA

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family. TdcD subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=402, Percent_Identity=99.5024875621891, Blast_Score=819, Evalue=0.0,
Organism=Escherichia coli, GI1788633, Length=396, Percent_Identity=43.6868686868687, Blast_Score=313, Evalue=9e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.15 [H]

Molecular weight: Translated: 43370; Mature: 43370

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2 ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSY
CCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCH
EGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNY
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCCHHHHH
ANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPKAYLYGLPWKYYEELGVRRYGFHGTSHR
CCCCHHHHHHHHCCCCEEEEEEECHHHHHHCCCCEEECCCHHHHHHCCCEEECCCCCCHH
YVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDV
HHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCHHHHHEECCCCCCC
DFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTF
CCHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHH
VHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSC
HHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCHH
GERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
HHHHHCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSY
CCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCH
EGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNY
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCCHHHHH
ANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPKAYLYGLPWKYYEELGVRRYGFHGTSHR
CCCCHHHHHHHHCCCCEEEEEEECHHHHHHCCCCEEECCCHHHHHHCCCEEECCCCCCHH
YVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDV
HHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCHHHHHEECCCCCCC
DFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTF
CCHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHH
VHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSC
HHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCHH
GERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
HHHHHCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA