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The map label for this gene is citG

Identifier: 157156539

GI number: 157156539

Start: 669304

End: 670182

Strand: Reverse

Name: citG

Synonym: EcE24377A_0635

Alternate gene names: 157156539

Gene position: 670182-669304 (Counterclockwise)

Preceding gene: 157154930

Following gene: 157155862

Centisome position: 13.46

GC content: 55.29

Gene sequence:

>879_bases
ATGTCGATGCCTGCAACGTCAACTAAAACCACAAAGCTTGCGACGTCATTAATCGATGAGTACGCCCTGCTGGGCTGGCG
CGCCATGCTGACTGAAGTCAATCTGTCACCGAAACCAGGCCTCGTGGATCGGATTAACTGCGGTGCGCATAAAGATATGG
CGCTGGAAGATTTCCACCGCAGCGCGCTGGCGATTCAGGGCTGGCTACCCCGTTTCATTGAATTTGGTGCCTGTAGTGCG
GAAATGGCACCAGAAGCGGTACTCCACGGATTACGCCCAATTGGTATGGCTTGCGAAGGTGATATGTTCCGCGCCACTGC
GGGCGTAAACACGCATAAAGGCAGCATTTTTTCTTTAGGGCTGCTATGTGCGGCAATTGGCCGTTTGCTTCAGCTCAACC
AGCCGGTAACGCCAACAACCGTTTGTTCTACGGCGGCAAGTTTCTGCCGTGGTCTGACCGATCGCGAACTGCGTACCAAT
AATTCACAACTGACGGCAGGTCAACGGTTGTACCAGCAGCTTGGCCTTACCGGCGCACGCGGTGAAGCCGAAGCGGGTTA
TCCACTAGTGCTCAACCACGCCCTGCCGCATTACCTCACTCTGCTGGATCAGGGGTTAGATCCTGAACTGGCATTGCTCG
ATACCTTGCTCCTACTGATGGCGATCAACGGCGATACCAACGTTGCATCGCGCGGTGGCGAGGGGGGCCTGCGCTGGCTA
CAGCGCGAGGCGCAAACATTATTGCAAAAAGGGGGCATTCGAACCCCCGCCGATCTCGATTATCTCCGGCAGTTCGACAG
GGAGTGTATCGAACGAAATCTCAGTCCAGGCGGCAGTGCCGACCTGCTGATCCTTACCTGGTTTTTAGCACAGATTTAA

Upstream 100 bases:

>100_bases
CGCAGCTGCCTGTTGTGCGAGCAAAGCGCAGCCGTCTGCGCGCGTGGAAAAACCCATCAACTGACCGATTTACTCAACCG
CATGGAGGCACTGCTGAACG

Downstream 100 bases:

>100_bases
TTATTTAAGCACTTGATAAATTTGGAAATATTAATTTTCGGAGAACCCGTATGTCTTTAGCAAAAGATAATATATGGAAA
CTATTGGCCCCACTGGTGGT

Product: triphosphoribosyl-dephospho-CoA synthase

Products: NA

Alternate protein names: 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSA
EMAPEAVLHGLRPIGMACEGDMFRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTN
NSQLTAGQRLYQQLGLTGARGEAEAGYPLVLNHALPHYLTLLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWL
QREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI

Sequences:

>Translated_292_residues
MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSA
EMAPEAVLHGLRPIGMACEGDMFRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTN
NSQLTAGQRLYQQLGLTGARGEAEAGYPLVLNHALPHYLTLLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWL
QREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI
>Mature_291_residues
SMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAE
MAPEAVLHGLRPIGMACEGDMFRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTNN
SQLTAGQRLYQQLGLTGARGEAEAGYPLVLNHALPHYLTLLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWLQ
REAQTLLQKGGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI

Specific function: Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A, the precursor of the prosthetic group of the holo-acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitG/MdcB family

Homologues:

Organism=Escherichia coli, GI1786830, Length=292, Percent_Identity=99.6575342465753, Blast_Score=593, Evalue=1e-171,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CITG_ECO24 (A7ZIZ9)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001461778.1
- ProteinModelPortal:   A7ZIZ9
- STRING:   A7ZIZ9
- EnsemblBacteria:   EBESCT00000022732
- GeneID:   5588447
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_0635
- NMPDR:   fig|331111.3.peg.3163
- eggNOG:   COG1767
- GeneTree:   EBGT00050000010972
- HOGENOM:   HBG305005
- OMA:   QQGGIRT
- ProtClustDB:   PRK10096
- BioCyc:   ECOL331111:ECE24377A_0635-MONOMER
- GO:   GO:0016310
- HAMAP:   MF_00397
- InterPro:   IPR002736
- InterPro:   IPR017551
- TIGRFAMs:   TIGR03125

Pfam domain/function: PF01874 CitG

EC number: =2.7.8.25

Molecular weight: Translated: 31645; Mature: 31514

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
SALAIQGWLPRFIEFGACSAEMAPEAVLHGLRPIGMACEGDMFRATAGVNTHKGSIFSLG
HHHHHHHHHHHHHHHCCCCHHCCHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHH
LLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTNNSQLTAGQRLYQQLGLTGAR
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCC
GEAEAGYPLVLNHALPHYLTLLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWL
CCCCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHH
QREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
SMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
SALAIQGWLPRFIEFGACSAEMAPEAVLHGLRPIGMACEGDMFRATAGVNTHKGSIFSLG
HHHHHHHHHHHHHHHCCCCHHCCHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHH
LLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTNNSQLTAGQRLYQQLGLTGAR
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCC
GEAEAGYPLVLNHALPHYLTLLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWL
CCCCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHH
QREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA