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The map label for this gene is ddpB

Identifier: 157156157

GI number: 157156157

Start: 1669751

End: 1670773

Strand: Reverse

Name: ddpB

Synonym: EcE24377A_1675

Alternate gene names: 157156157

Gene position: 1670773-1669751 (Counterclockwise)

Preceding gene: 157156046

Following gene: 157155791

Centisome position: 33.55

GC content: 55.03

Gene sequence:

>1023_bases
GTGACCTTCTGGAGTATTTTACGCCAACGCTGCTGGGGGCTGGTGCTCGTGGTGGCGGGCGTCTGCGTGATTACGTTTAT
TATCTCGCATCTGATCCCTGGCGATCCGGCGCGGTTACTGGCGGGTGACCGCGCCAGCGATGCTATCGTGGAAAATATTC
GCCAGCAACTGGGACTGGACCAGCCACTGTATGTACAGTTTTACCGCTACGTCAGCGACCTGTTTCATGGTGACCTGGGA
ACATCCATTCGTACCGGGCGTCCGGTGCTGGAAGAGTTGCGTATATTTTTCCCGGCGACGCTGGAGCTGGCTTTTGGTGC
CCTGCTGCTGGCACTCCTGATTGGCATCCCGCTGGGCATACTCTCTGCAGTCTGGCGAAATCGCTGGCTGGATCATCTGG
TGCGAATAATGGCCATTACCGGAATCTCCACACCTGCGTTCTGGCTTGGGCTGGGCGTCATTGTGCTGTTTTATGGTCAT
CTGCAAATTCTTCCCGGCGGCGGAAGGCTTGATGACTGGCTGGATCCACCAACGCACGTTACCGGCTTTTATCTGCTCGA
TGCGCTGCTTGAAGGCAACGGTGAAGTCTTCTTCAATGCGTTGCAACATCTCATCTTACCGGCATTAACGCTGGCGTTCG
TTCACCTGGGAATTGTCGCTCGCCAGATCCGCTCAGCGATGCTGGAACAATTGAGTGAAGACTACATTCGTACCGCCCGG
GCCAGCGGCTTGCCCGGCTGGTATATCGTTTTATGTTATGCGCTACCCAATGCGTTGATCCCATCGATTACCGTATTGGG
TTTGGCGCTGGGCGATTTGTTGTATGGCGCAGTGCTCACCGAAACCGTTTTTGCCTGGCCCGGAATGGGTGCATGGGTAG
TAACATCAATACAGGCGCTCGACTTCCCGGCAGTGATGGGCTTTGCCGTCGTGGTTTCATTTGCTTATGTGCTGGTCAAC
CTGGTGGTGGATTTGCTCTATTTGTGGATTGATCCGCGTATCGGACGTGGAGGTGGTGAATGA

Upstream 100 bases:

>100_bases
CAGAAAAACTACCAACTGGCGATGAACAAAGAGGTGAAAGGCTTTGTGTTCAATCCCATGCTGGAACAGGTCTTCAATAT
CAATACCATGAGTAAATAAC

Downstream 100 bases:

>100_bases
TGCTAAGCGAGGAAACGTCCGCCGTACGCCCACAAAAACAAACGCGATTTAACGGTGCAAAACTGGTATGGATGCTGAAA
GGCAGTCCGCTCACCGTGAC

Product: inner membrane ABC transporter permease protein yddR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTFWSILRQRCWGLVLVVAGVCVITFIISHLIPGDPARLLAGDRASDAIVENIRQQLGLDQPLYVQFYRYVSDLFHGDLG
TSIRTGRPVLEELRIFFPATLELAFGALLLALLIGIPLGILSAVWRNRWLDHLVRIMAITGISTPAFWLGLGVIVLFYGH
LQILPGGGRLDDWLDPPTHVTGFYLLDALLEGNGEVFFNALQHLILPALTLAFVHLGIVARQIRSAMLEQLSEDYIRTAR
ASGLPGWYIVLCYALPNALIPSITVLGLALGDLLYGAVLTETVFAWPGMGAWVVTSIQALDFPAVMGFAVVVSFAYVLVN
LVVDLLYLWIDPRIGRGGGE

Sequences:

>Translated_340_residues
MTFWSILRQRCWGLVLVVAGVCVITFIISHLIPGDPARLLAGDRASDAIVENIRQQLGLDQPLYVQFYRYVSDLFHGDLG
TSIRTGRPVLEELRIFFPATLELAFGALLLALLIGIPLGILSAVWRNRWLDHLVRIMAITGISTPAFWLGLGVIVLFYGH
LQILPGGGRLDDWLDPPTHVTGFYLLDALLEGNGEVFFNALQHLILPALTLAFVHLGIVARQIRSAMLEQLSEDYIRTAR
ASGLPGWYIVLCYALPNALIPSITVLGLALGDLLYGAVLTETVFAWPGMGAWVVTSIQALDFPAVMGFAVVVSFAYVLVN
LVVDLLYLWIDPRIGRGGGE
>Mature_339_residues
TFWSILRQRCWGLVLVVAGVCVITFIISHLIPGDPARLLAGDRASDAIVENIRQQLGLDQPLYVQFYRYVSDLFHGDLGT
SIRTGRPVLEELRIFFPATLELAFGALLLALLIGIPLGILSAVWRNRWLDHLVRIMAITGISTPAFWLGLGVIVLFYGHL
QILPGGGRLDDWLDPPTHVTGFYLLDALLEGNGEVFFNALQHLILPALTLAFVHLGIVARQIRSAMLEQLSEDYIRTARA
SGLPGWYIVLCYALPNALIPSITVLGLALGDLLYGAVLTETVFAWPGMGAWVVTSIQALDFPAVMGFAVVVSFAYVLVNL
VVDLLYLWIDPRIGRGGGE

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport. Probably responsible for the translocation of the substrate across the membrane

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1787761, Length=340, Percent_Identity=100, Blast_Score=668, Evalue=0.0,
Organism=Escherichia coli, GI1789965, Length=318, Percent_Identity=44.0251572327044, Blast_Score=267, Evalue=9e-73,
Organism=Escherichia coli, GI1787053, Length=326, Percent_Identity=41.1042944785276, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI1789888, Length=334, Percent_Identity=36.2275449101796, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1787550, Length=266, Percent_Identity=35.3383458646617, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1787497, Length=328, Percent_Identity=30.4878048780488, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1788504, Length=302, Percent_Identity=24.1721854304636, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DDPB_ECOLI (P77308)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   A64902
- RefSeq:   AP_002109.1
- RefSeq:   NP_416003.1
- ProteinModelPortal:   P77308
- DIP:   DIP-11671N
- STRING:   P77308
- EnsemblBacteria:   EBESCT00000003090
- EnsemblBacteria:   EBESCT00000016931
- GeneID:   946044
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1481
- KEGG:   eco:b1486
- EchoBASE:   EB3550
- EcoGene:   EG13789
- eggNOG:   COG0601
- GeneTree:   EBGT00050000009815
- HOGENOM:   HBG724229
- OMA:   GVVARQI
- ProtClustDB:   CLSK880043
- BioCyc:   EcoCyc:YDDR-MONOMER
- Genevestigator:   P77308
- InterPro:   IPR000515

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 37346; Mature: 37214

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1da415e0)-; HASH(0x1dbab8e0)-; HASH(0x1d899274)-; HASH(0x1d43fab0)-; HASH(0x1dc21884)-; HASH(0x1db90ad0)-; HASH(0x1db75a1c)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFWSILRQRCWGLVLVVAGVCVITFIISHLIPGDPARLLAGDRASDAIVENIRQQLGLD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHCCC
QPLYVQFYRYVSDLFHGDLGTSIRTGRPVLEELRIFFPATLELAFGALLLALLIGIPLGI
CHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAVWRNRWLDHLVRIMAITGISTPAFWLGLGVIVLFYGHLQILPGGGRLDDWLDPPTHV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHH
TGFYLLDALLEGNGEVFFNALQHLILPALTLAFVHLGIVARQIRSAMLEQLSEDYIRTAR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGLPGWYIVLCYALPNALIPSITVLGLALGDLLYGAVLTETVFAWPGMGAWVVTSIQAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
DFPAVMGFAVVVSFAYVLVNLVVDLLYLWIDPRIGRGGGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
>Mature Secondary Structure 
TFWSILRQRCWGLVLVVAGVCVITFIISHLIPGDPARLLAGDRASDAIVENIRQQLGLD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHCCC
QPLYVQFYRYVSDLFHGDLGTSIRTGRPVLEELRIFFPATLELAFGALLLALLIGIPLGI
CHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAVWRNRWLDHLVRIMAITGISTPAFWLGLGVIVLFYGHLQILPGGGRLDDWLDPPTHV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHH
TGFYLLDALLEGNGEVFFNALQHLILPALTLAFVHLGIVARQIRSAMLEQLSEDYIRTAR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGLPGWYIVLCYALPNALIPSITVLGLALGDLLYGAVLTETVFAWPGMGAWVVTSIQAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
DFPAVMGFAVVVSFAYVLVNLVVDLLYLWIDPRIGRGGGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644