BacMap

Definition	Escherichia coli E24377A, complete genome.
Accession	NC_009801
Length	4,979,619

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The map label for this gene is yeaE [H]

Identifier: 157155366

GI number: 157155366

Start: 1990407

End: 1991261

Strand: Reverse

Name: yeaE [H]

Synonym: EcE24377A_2005

Alternate gene names: 157155366

Gene position: 1991261-1990407 (Counterclockwise)

Preceding gene: 157156122

Following gene: 157156280

Centisome position: 39.99

GC content: 50.53

Gene sequence:

>855_bases
ATGCAACAAAAAATGATTCAATTTAGTGGCGATGTCTCACTGCCAGTCATAGGGCAGGGAACATGGTATATGGGCGAAGA
TGCCAGTCAGCGCAAAACAGAAGTTGCTGCACTACGCGCGGGCATTGAACTCGGTTTAACCCTCATTGATACCGCCGAAA
TGTATGCCGATGGCGGTGCCGAAAAGGTGGTTGGGGAAGCATTAACCGGTCTGCGCGATAACGTCTTTCTCGTCTCTAAA
GTCTATCCGTGGAATGCTGGCGGGCAAAAAGCGATAAATGCATGCGAAGCCAGTTTACGCCGTCTCAATACTGATTATCT
CGATCTCTACTTATTACACTGGTCTGGCAGTTTCGCTTTTGAAGAGACTGTTGCAGCGATGGAAAAATTGAGCGCCCAGG
GAAAAATCCGCCGCTGGGGCGTTTCTAACCTTGATTATGCTGATATGCAGGAACTCTGGCAGCTGCCGGGGGGAAATCAG
TGTGCCACTAATCAGGTGCTTTACCATCTCGGTTCACGAGGGATTGAGTACGATCTACTCCCCTGGTGCCAGCAACAGCA
GATGCCGGTGATGGCTTACAGTCCATTAGCCCAGGCCGGGCGGTTGCGCAATGGACTGTTAAAAAACGCGGTAGTCAACG
AAATTGCACATGCTCACAATATCAGCGCGGCACAAGTATTGTTGGCGTGGGTAATCAGCCATCAGGGTGTGATGGCGATT
CCAAAAGCGGCCACGATTGCCCATGTCCAACAAAATGCAGCTGCGCTTGAGGTCGAACTTTCGTCAGCGGAATTAGCTAT
GCTGGATAAGGCATATCCGGCACCAAAAGGAAAAACTGCGCTGGATATGGTGTGA

Upstream 100 bases:

>100_bases
ACAAATTCTGATAATGCATCTTTCCAGGGCATTTTGTGCATAAAAACAGGGCGTCACGCCCTGTTTTGCATTACGGTGGT
GCAATACCTGGGAGGAAACA

Downstream 100 bases:

>100_bases
TGTTGATACGTGCCGGATGCATCGCACCCGGCACACAACATTAACGCAAATTAACGTTTCGCAACGCGAATGGATTGCGC
CAGATGTGCAGGTTTCTCTT

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MQQKMIQFSGDVSLPVIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLRDNVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAFEETVAAMEKLSAQGKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
PKAATIAHVQQNAAALEVELSSAELAMLDKAYPAPKGKTALDMV

Sequences:

>Translated_284_residues
MQQKMIQFSGDVSLPVIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLRDNVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAFEETVAAMEKLSAQGKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
PKAATIAHVQQNAAALEVELSSAELAMLDKAYPAPKGKTALDMV
>Mature_284_residues
MQQKMIQFSGDVSLPVIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLRDNVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAFEETVAAMEKLSAQGKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
PKAATIAHVQQNAAALEVELSSAELAMLDKAYPAPKGKTALDMV

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI223468663, Length=297, Percent_Identity=29.2929292929293, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI291291012, Length=265, Percent_Identity=30.188679245283, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI5174695, Length=302, Percent_Identity=27.4834437086093, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI93277124, Length=305, Percent_Identity=26.5573770491803, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI24497577, Length=290, Percent_Identity=28.2758620689655, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI5174391, Length=290, Percent_Identity=28.2758620689655, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI300116273, Length=285, Percent_Identity=28.4210526315789, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI310109922, Length=275, Percent_Identity=28.7272727272727, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI300116271, Length=281, Percent_Identity=27.7580071174377, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI4502049, Length=291, Percent_Identity=29.2096219931272, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI24497585, Length=290, Percent_Identity=27.5862068965517, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI45446745, Length=295, Percent_Identity=27.1186440677966, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4503285, Length=295, Percent_Identity=27.1186440677966, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI310109920, Length=295, Percent_Identity=27.1186440677966, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5453543, Length=295, Percent_Identity=26.7796610169492, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI24497583, Length=291, Percent_Identity=26.8041237113402, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI223718702, Length=182, Percent_Identity=32.4175824175824, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1788081, Length=284, Percent_Identity=97.887323943662, Blast_Score=573, Evalue=1e-165,
Organism=Escherichia coli, GI1786400, Length=269, Percent_Identity=28.996282527881, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87081735, Length=301, Percent_Identity=28.9036544850498, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1788070, Length=313, Percent_Identity=27.4760383386581, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082198, Length=262, Percent_Identity=28.2442748091603, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789199, Length=351, Percent_Identity=28.2051282051282, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789375, Length=323, Percent_Identity=24.4582043343653, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787674, Length=259, Percent_Identity=23.9382239382239, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994888, Length=235, Percent_Identity=30.6382978723404, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17561298, Length=280, Percent_Identity=31.0714285714286, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17552492, Length=273, Percent_Identity=29.6703296703297, Blast_Score=113, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI71998625, Length=277, Percent_Identity=29.9638989169675, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17564128, Length=307, Percent_Identity=27.3615635179153, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17537077, Length=297, Percent_Identity=28.6195286195286, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17538386, Length=290, Percent_Identity=29.3103448275862, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17537075, Length=297, Percent_Identity=28.6195286195286, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17561300, Length=293, Percent_Identity=27.9863481228669, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17566692, Length=299, Percent_Identity=25.0836120401338, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17550248, Length=297, Percent_Identity=24.2424242424242, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17537079, Length=302, Percent_Identity=21.523178807947, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324694, Length=293, Percent_Identity=27.6450511945392, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320079, Length=273, Percent_Identity=28.2051282051282, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6322556, Length=283, Percent_Identity=26.8551236749117, Blast_Score=83, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323998, Length=305, Percent_Identity=25.2459016393443, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6319958, Length=294, Percent_Identity=24.8299319727891, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644950, Length=312, Percent_Identity=32.0512820512821, Blast_Score=120, Evalue=8e-28,
Organism=Drosophila melanogaster, GI221378297, Length=332, Percent_Identity=30.7228915662651, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI45553081, Length=290, Percent_Identity=24.4827586206897, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24657054, Length=286, Percent_Identity=25.8741258741259, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24663317, Length=299, Percent_Identity=23.0769230769231, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24662789, Length=309, Percent_Identity=26.2135922330097, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281366140, Length=252, Percent_Identity=25.3968253968254, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI20129731, Length=297, Percent_Identity=24.9158249158249, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356425, Length=287, Percent_Identity=24.390243902439, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24662781, Length=288, Percent_Identity=25.6944444444444, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 30947; Mature: 30947

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQKMIQFSGDVSLPVIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGA
CCCCEEEECCCCCCEEECCCCEECCCCCHHHHHHHHHHHHHHHHCEEEEEHHHHHHCCCH
EKVVGEALTGLRDNVFLVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAF
HHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH
EETVAAMEKLSAQGKIRRWGVSNLDYADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLL
HHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCC
PWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEC
PKAATIAHVQQNAAALEVELSSAELAMLDKAYPAPKGKTALDMV
CCHHHHHHHHHCCEEEEEEECCHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQQKMIQFSGDVSLPVIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGA
CCCCEEEECCCCCCEEECCCCEECCCCCHHHHHHHHHHHHHHHHCEEEEEHHHHHHCCCH
EKVVGEALTGLRDNVFLVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAF
HHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH
EETVAAMEKLSAQGKIRRWGVSNLDYADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLL
HHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCC
PWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEC
PKAATIAHVQQNAAALEVELSSAELAMLDKAYPAPKGKTALDMV
CCHHHHHHHHHCCEEEEEEECCHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]