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The map label for this gene is ygeV [H]

Identifier: 157155317

GI number: 157155317

Start: 3207650

End: 3209428

Strand: Reverse

Name: ygeV [H]

Synonym: EcE24377A_3194

Alternate gene names: 157155317

Gene position: 3209428-3207650 (Counterclockwise)

Preceding gene: 157155346

Following gene: 157158148

Centisome position: 64.45

GC content: 45.53

Gene sequence:

>1779_bases
ATGGAGCTTGCTACTACGCAGTCAGTATTGATGCAAATTCAACCGACAATTCAGCGTTTTGCCAGAATGCTTGCCAGCGT
TTTGCAGCTTGAGGTTGAGATCGTTGATGAAAACTTGTGTCGCGTCGCCGGAACGGGCGCGTATGGGAAGTTTCTTGGTC
GCCAGTTGAGCGGCAACTCACGCCTGCTCCGCCACGTCCTGGAAACGAAAACTGAAAAAGTTGTGACACAGTCTCGCTTC
GATCCCCTTTGCGAAGGTTGCGATAGTAAAGAAAATTGCCGTGAAAAAGCATTTCTGGGTACGCCTGTCATTTTACAGGA
TCGTTGTGTTGGGGTGATAAGTTTGATTGCCGTTATCCACGAGCAACAAGAGCATATCAGTGATAATTTACGCGAATTTT
CTGATTATGTTCGCCATATATCCACCATTTTTGTTTCGAAACTTCTGGAGGATCAGGGGCCAGGAGATAACATCAGTAAA
ATATTCGCGACCATGATCGATAATATGGATCAGGGCGTATTAGTTGTTGATGATGAAAGTCGGGTTCAGTTTGTTAATCA
GACTGCCTTAAAAACACTTGGTGTTGTACAAAATAATATTATTGGGAAACCTATCCGTTTCAGACCATTAACATTTGAGA
GTAATTTTACTCATGGACATATGCAGCATATTGTTTCGTGGGACGATAAAAGTGAATTAATCATTGGTCAATTGCATAAC
ATTCAGGGCCGACAATTATTTTTAATGGCATTTCACCAATCGCATACCAGTTTTTCTGTAGCAAATGCACCTGATGAACC
ACATATTGAACAATTGGTTGGCGAGTGCCGTGTTATGCGGCAATTAAAACGACTCATTAGCCGTATTGCACCCAGCCCAT
CCAGCGTTATGGTGGTTGGTGAAAGCGGCACGGGTAAAGAAGTCGTCGCCCGAGCAATCCATAAGTTGAGCGGAAGACGG
AATAAACCCTTTATTGCTATCAACTGTGCCGCGATTCCGGAGCAGCTTCTGGAAAGCGAACTGTTCGGTTATGTTAAAGG
CGCATTTACTGGCGCTTCTGCCAACGGTAAAACAGGGTTGATTCAGGTGGCGAATACGGGCACGCTGTTTCTCGATGAAA
TAGGTGATATGCCATTAATGTTGCAGGCTAAATTACTGCGCGCTATTGAGGCGCGTGAAATTCTGCCGATTGGTGCCAGT
AGCCCAATACAAGTCGACATTCGCATCATTTCTGCAACTAATCAGAATTTGGCCCAGTTCATTGCCGAAGGTAAATTCCG
CGAAGATCTCTTCTACCGACTTAATGTTATCCCGATAACTCTGCCACCGCTGCGTGAACGTCAGGAAGATATTGAACTAT
TGGTGCATTACTTTTTACATCTGCATACCCGTCGTCTGGGATCGGTTTATCCTGGCATTGCTCCCGATGTCGTCGAAATA
TTGCGTAAGCATCGTTGGCCCGGAAACCTGCGCGAGTTAAGCAATTTGATGGAATATCTGGTTAACGTAGTTCCTTCAGG
TGAAGTTATCGACAGCACGCTATTGCCGCCAAATCTGCTGAATAATGGCACAACGGAGCAAAGTGATGTAACAGAGGTCA
GTGAGGCGCACCTGTCACTCGATGATGCGGGCGGCACGGCGCTGGAGGAGATGGAAAAGCAAATGATCCGCGAGGCGCTT
TCACGTCATAACAGCAAGAAGCAAGTTGCTGATGAACTGGGCATCGGCATTGCTACGCTCTATCGCAAGATTAAGAAATA
TGAGTTGTTAAACATATAA

Upstream 100 bases:

>100_bases
TTTTATCAAAGCCAATTTCGCCTGAGTTAATATCATCATGATCTGTGAACCATCAACGTCTTCAATGATCGACTTTTAAG
TAAGTCTGGAAGGTAAAGCT

Downstream 100 bases:

>100_bases
CCTCAGTGAATCCGGCCTGAATTCAGGCCGGATATCCTTTTACTTCGTTTTCTCGCAATCCAGAACTGTATTTACAATCA
TCTGATACCCCGTGCAGCGA

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLCRVAGTGAYGKFLGRQLSGNSRLLRHVLETKTEKVVTQSRF
DPLCEGCDSKENCREKAFLGTPVILQDRCVGVISLIAVIHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISK
IFATMIDNMDQGVLVVDDESRVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTHGHMQHIVSWDDKSELIIGQLHN
IQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGECRVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRR
NKPFIAINCAAIPEQLLESELFGYVKGAFTGASANGKTGLIQVANTGTLFLDEIGDMPLMLQAKLLRAIEAREILPIGAS
SPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEI
LRKHRWPGNLRELSNLMEYLVNVVPSGEVIDSTLLPPNLLNNGTTEQSDVTEVSEAHLSLDDAGGTALEEMEKQMIREAL
SRHNSKKQVADELGIGIATLYRKIKKYELLNI

Sequences:

>Translated_592_residues
MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLCRVAGTGAYGKFLGRQLSGNSRLLRHVLETKTEKVVTQSRF
DPLCEGCDSKENCREKAFLGTPVILQDRCVGVISLIAVIHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISK
IFATMIDNMDQGVLVVDDESRVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTHGHMQHIVSWDDKSELIIGQLHN
IQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGECRVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRR
NKPFIAINCAAIPEQLLESELFGYVKGAFTGASANGKTGLIQVANTGTLFLDEIGDMPLMLQAKLLRAIEAREILPIGAS
SPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEI
LRKHRWPGNLRELSNLMEYLVNVVPSGEVIDSTLLPPNLLNNGTTEQSDVTEVSEAHLSLDDAGGTALEEMEKQMIREAL
SRHNSKKQVADELGIGIATLYRKIKKYELLNI
>Mature_592_residues
MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLCRVAGTGAYGKFLGRQLSGNSRLLRHVLETKTEKVVTQSRF
DPLCEGCDSKENCREKAFLGTPVILQDRCVGVISLIAVIHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISK
IFATMIDNMDQGVLVVDDESRVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTHGHMQHIVSWDDKSELIIGQLHN
IQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGECRVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRR
NKPFIAINCAAIPEQLLESELFGYVKGAFTGASANGKTGLIQVANTGTLFLDEIGDMPLMLQAKLLRAIEAREILPIGAS
SPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEI
LRKHRWPGNLRELSNLMEYLVNVVPSGEVIDSTLLPPNLLNNGTTEQSDVTEVSEAHLSLDDAGGTALEEMEKQMIREAL
SRHNSKKQVADELGIGIATLYRKIKKYELLNI

Specific function: Unknown

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=591, Percent_Identity=99.492385786802, Blast_Score=1209, Evalue=0.0,
Organism=Escherichia coli, GI1788550, Length=306, Percent_Identity=47.7124183006536, Blast_Score=251, Evalue=8e-68,
Organism=Escherichia coli, GI1790299, Length=329, Percent_Identity=43.4650455927052, Blast_Score=248, Evalue=1e-66,
Organism=Escherichia coli, GI87082117, Length=328, Percent_Identity=42.3780487804878, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1789087, Length=321, Percent_Identity=42.3676012461059, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1790437, Length=318, Percent_Identity=42.4528301886792, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1788905, Length=252, Percent_Identity=48.015873015873, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1786524, Length=330, Percent_Identity=38.4848484848485, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI87082152, Length=322, Percent_Identity=38.8198757763975, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87081872, Length=232, Percent_Identity=44.8275862068966, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI1787583, Length=349, Percent_Identity=32.6647564469914, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1789828, Length=264, Percent_Identity=35.6060606060606, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI87081858, Length=450, Percent_Identity=28.8888888888889, Blast_Score=146, Evalue=4e-36,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR000014
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 66122; Mature: 66122

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLCRVAGTGAYGKFLGRQLSGNS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCH
RLLRHVLETKTEKVVTQSRFDPLCEGCDSKENCREKAFLGTPVILQDRCVGVISLIAVIH
HHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
EQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISKIFATMIDNMDQGVLVVDDES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECCH
RVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTHGHMQHIVSWDDKSELIIGQLHN
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCEEHHHHCC
IQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGECRVMRQLKRLISRIAPSPSSVMVVG
CCCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
ESGTGKEVVARAIHKLSGRRNKPFIAINCAAIPEQLLESELFGYVKGAFTGASANGKTGL
CCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
IQVANTGTLFLDEIGDMPLMLQAKLLRAIEAREILPIGASSPIQVDIRIISATNQNLAQF
EEEECCCEEEHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEEECCCHHHHHH
IAEGKFREDLFYRLNVIPITLPPLRERQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEI
HHCCCHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LRKHRWPGNLRELSNLMEYLVNVVPSGEVIDSTLLPPNLLNNGTTEQSDVTEVSEAHLSL
HHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHCC
DDAGGTALEEMEKQMIREALSRHNSKKQVADELGIGIATLYRKIKKYELLNI
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLCRVAGTGAYGKFLGRQLSGNS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCH
RLLRHVLETKTEKVVTQSRFDPLCEGCDSKENCREKAFLGTPVILQDRCVGVISLIAVIH
HHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
EQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISKIFATMIDNMDQGVLVVDDES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECCH
RVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTHGHMQHIVSWDDKSELIIGQLHN
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCEEHHHHCC
IQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGECRVMRQLKRLISRIAPSPSSVMVVG
CCCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
ESGTGKEVVARAIHKLSGRRNKPFIAINCAAIPEQLLESELFGYVKGAFTGASANGKTGL
CCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
IQVANTGTLFLDEIGDMPLMLQAKLLRAIEAREILPIGASSPIQVDIRIISATNQNLAQF
EEEECCCEEEHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEEECCCHHHHHH
IAEGKFREDLFYRLNVIPITLPPLRERQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEI
HHCCCHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LRKHRWPGNLRELSNLMEYLVNVVPSGEVIDSTLLPPNLLNNGTTEQSDVTEVSEAHLSL
HHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHCC
DDAGGTALEEMEKQMIREALSRHNSKKQVADELGIGIATLYRKIKKYELLNI
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]