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The map label for this gene is eutH

Identifier: 157155308

GI number: 157155308

Start: 2716810

End: 2718036

Strand: Reverse

Name: eutH

Synonym: EcE24377A_2729

Alternate gene names: 157155308

Gene position: 2718036-2716810 (Counterclockwise)

Preceding gene: 157154795

Following gene: 157159089

Centisome position: 54.58

GC content: 54.93

Gene sequence:

>1227_bases
ATGGGAATTAACGAAATCATCATGTACATCATGATGTTCTTTATGCTGATAGCTGCCGTAGACAGGATCCTGTCGCAGTT
CGGCGGTTCTGCTCGTTTCCTCGGTAAGTTCGGTAAAAGTATCGAAGGATCAGGCGGTCAGTTCGAAGAAGGCTTTATGG
CAATGGGCGCTCTGGGTCTGGCGATGGTCGGTATGACCGCGCTGGCACCGGTACTGGCTCACGTACTCGGGCCGGTAATT
ATCCCGGTTTACGAAATGCTCGGCGCAAACCCGTCAATGTTCGCCGGAACGCTGCTGGCGTGCGATATGGGCGGTTTCTT
CCTCGCCAAAGAGCTGGCGGGCGGCGACGTAGCAGCGTGGCTATACTCTGGGTTAATTCTTGGGTCGATGATGGGGCCAA
CGATTGTGTTTTCCATTCCGGTGGCGCTCGGCATTATCGAACCTTCTGACCGTCGTTATCTGGCGCTCGGCGTGCTGGCG
GGCATTGTGACCATTCCGATTGGCTGTATTGCTGGTGGTCTGGTTGCTATGTACTCCGGTGTGCAGATCAACGGTCAGCC
GGTGGAATTCACTTTCGCCCTGATCCTGATGAACATGATCCCGGTGATCATTGTCGCGATTCTGGTGGCGCTGGGGCTGA
AATTCATCCCGGAAAAAATGATCAACGGCTTCCAGATCTTCGCCAAATTCCTCGTTGCATTGATCACCCTCGGTCTTGCC
GCTGCGGTAGTGAAATTCCTGCTTGGCTGGGAACTGATCCCCGGTCTGGATCCTATCTTTATGGCCCCTGGCGATAAACC
CGGTGAAGTGATGCGCGCCATTGAAGTTATCGGTTCTATCTCCTGCGTGCTGTTAGGGGCGTATCCAATGGTGCTGCTGC
TGACTCGCTGGTTTGAAAAACCGCTGATGAGCGTCGGTAAAGTACTGAATATGAACAACATCGCGGCAGCCGGCATGGTG
GCAACGCTTGCCAACAACATCCCGATGTTCGGCATGATGAAGCAGATGGATACCCGCGGCAAAGTCATCAACTGCGCCTT
CGCCGTTTCCGCTGCTTTCGCCCTGGGCGACCACTTAGGCTTCGCCGCTGCCAACATGAACGCCATGATCTTCCCGATGA
TTGTCGGCAAGTTGATCGGCGGCGTAACGGCGATTGGCGTGGCGATGATGCTGGTGCCAAAAGAAGACGCGACCGCGACT
AAAACCGAAGCGGAGGCACAATCGTGA

Upstream 100 bases:

>100_bases
TTGCCGCGTCTGATCCGGCCTTCGGGATTGCACATGTAGGGCGGATAAGGCGTTTACGCCGCATCCGCCAATAAATAACA
ACTAACAGGGAGTAAAGGCG

Downstream 100 bases:

>100_bases
ACACTCGCCAGCTATTGAGCGTCGGTATCGATATCGGCACCACCACCACCCAGGTGATTTTCTCCCACCTGGAGCTGGTT
AACCGTGCGGCGGTGTCGCA

Product: ethanolamine utilization protein EutH

Products: NA

Alternate protein names: Putative ethanolamine transporter

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MGINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGSGGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVI
IPVYEMLGANPSMFAGTLLACDMGGFFLAKELAGGDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA
GIVTIPIGCIAGGLVAMYSGVQINGQPVEFTFALILMNMIPVIIVAILVALGLKFIPEKMINGFQIFAKFLVALITLGLA
AAVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEVIGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMV
ATLANNIPMFGMMKQMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLVPKEDATAT
KTEAEAQS

Sequences:

>Translated_408_residues
MGINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGSGGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVI
IPVYEMLGANPSMFAGTLLACDMGGFFLAKELAGGDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA
GIVTIPIGCIAGGLVAMYSGVQINGQPVEFTFALILMNMIPVIIVAILVALGLKFIPEKMINGFQIFAKFLVALITLGLA
AAVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEVIGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMV
ATLANNIPMFGMMKQMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLVPKEDATAT
KTEAEAQS
>Mature_407_residues
GINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGSGGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVII
PVYEMLGANPSMFAGTLLACDMGGFFLAKELAGGDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLAG
IVTIPIGCIAGGLVAMYSGVQINGQPVEFTFALILMNMIPVIIVAILVALGLKFIPEKMINGFQIFAKFLVALITLGLAA
AVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEVIGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMVA
TLANNIPMFGMMKQMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLVPKEDATATK
TEAEAQS

Specific function: Possibly involved in the transport of ethanolamine from the periplasm to the cytoplasm

COG id: COG3192

COG function: function code E; Ethanolamine utilization protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eutH family

Homologues:

Organism=Escherichia coli, GI1788794, Length=408, Percent_Identity=100, Blast_Score=796, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EUTH_ECOLI (P76552)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   C65020
- RefSeq:   AP_003037.1
- RefSeq:   NP_416947.1
- ProteinModelPortal:   P76552
- DIP:   DIP-9533N
- MINT:   MINT-1296863
- STRING:   P76552
- EnsemblBacteria:   EBESCT00000002312
- EnsemblBacteria:   EBESCT00000018423
- GeneID:   944979
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW2436
- KEGG:   eco:b2452
- EchoBASE:   EB3934
- EcoGene:   EG14182
- eggNOG:   COG3192
- GeneTree:   EBGT00050000010858
- HOGENOM:   HBG304744
- OMA:   FGDHLGF
- ProtClustDB:   PRK15086
- BioCyc:   EcoCyc:G7282-MONOMER
- Genevestigator:   P76552
- GO:   GO:0006810
- InterPro:   IPR007441

Pfam domain/function: PF04346 EutH

EC number: NA

Molecular weight: Translated: 42808; Mature: 42676

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1cc68600)-; HASH(0x1f8576a0)-; HASH(0x1f350068)-; HASH(0x1edc2c70)-; HASH(0x1f18e534)-; HASH(0x1d42f8e4)-; HASH(0x1f857808)-; HASH(0x1f4ff8bc)-; HASH(0x1f85851c)-; HASH(0x1f801158)-; HASH(0x1f385658)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
8.1 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
7.9 %Met     (Mature Protein)
8.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGSGGQFEEGFMAMGALGL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AMVGMTALAPVLAHVLGPVIIPVYEMLGANPSMFAGTLLACDMGGFFLAKELAGGDVAAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCHHHHH
LYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLAGIVTIPIGCIAGGLVAMYSG
HHHHHHHHHHCCCHHHEEHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
VQINGQPVEFTFALILMNMIPVIIVAILVALGLKFIPEKMINGFQIFAKFLVALITLGLA
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEVIGSISCVLLGAYPMVLLLTRWFEK
HHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLMSVGKVLNMNNIAAAGMVATLANNIPMFGMMKQMDTRGKVINCAFAVSAAFALGDHLG
HHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHH
FAAANMNAMIFPMIVGKLIGGVTAIGVAMMLVPKEDATATKTEAEAQS
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHCCCH
>Mature Secondary Structure 
GINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGSGGQFEEGFMAMGALGL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AMVGMTALAPVLAHVLGPVIIPVYEMLGANPSMFAGTLLACDMGGFFLAKELAGGDVAAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCHHHHH
LYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLAGIVTIPIGCIAGGLVAMYSG
HHHHHHHHHHCCCHHHEEHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
VQINGQPVEFTFALILMNMIPVIIVAILVALGLKFIPEKMINGFQIFAKFLVALITLGLA
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEVIGSISCVLLGAYPMVLLLTRWFEK
HHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLMSVGKVLNMNNIAAAGMVATLANNIPMFGMMKQMDTRGKVINCAFAVSAAFALGDHLG
HHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHH
FAAANMNAMIFPMIVGKLIGGVTAIGVAMMLVPKEDATATKTEAEAQS
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503