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The map label for this gene is yjdL

Identifier: 157163596

GI number: 157163596

Start: 4378976

End: 4380433

Strand: Reverse

Name: yjdL

Synonym: EcHS_A4371

Alternate gene names: 157163596

Gene position: 4380433-4378976 (Counterclockwise)

Preceding gene: 157163597

Following gene: 157163595

Centisome position: 94.33

GC content: 51.44

Gene sequence:

>1458_bases
ATGAAAACACCCTCACAGCCGCGCGCGATATACTATATCGTGGCGATCCAAATCTGGGAGTACTTCAGTTTTTACGGCAT
GCGTGCCTTACTCATTCTCTATCTCACCCATCAGCTTGGTTTTGATGATAACCATGCCATCAGCCTGTTCAGCGCATATG
CTTCTCTGGTTTACGTTACCCCTATTCTCGGCGGCTGGCTTGCCGACCGCCTGCTCGGCAACCGCACTGCAGTGATTGCC
GGCGCGCTGTTAATGACCCTTGGCCATGTGGTGCTGGGCATTGATACAAATTCAACCTTTAGCCTGTATCTGGCGCTGGC
AATCATTATTTGTGGCTACGGTTTATTCAAATCAAACATCAGCTGTTTGCTTGGCGAGCTCTACGACGAGAACGATCATC
GACGTGATGGCGGTTTTTCGCTGCTGTATGCTGCGGGCAATATCGGTTCTATCGCCGCCCCAATCGCCTGCGGCCTGGCT
GCTCAGTGGTATGGATGGCATGTTGGCTTTGCCCTTGCGGGTGGCGGCATGTTTATCGGTTTGTTGATTTTCTTAAGCGG
GCATCGTCATTTCCAGTCCACGCGTAGTATGGATAAAAAAGCGCTCACTAGCGTGAAATTTGCCTTACCAGTATGGAGCT
GGTTAGTGGTGATGCTCTGTTTAGCCCCAGTATTTTTTACCCTGCTGCTGGAGAACGACTGGTCCGGATATTTGCTGGCG
ATCGTTTGCCTCATTGCCGCACAAATCATTGCCCGCATGATGATCAAATTCCCCGAACACCGCCGTGCTCTTTGGCAAAT
TGTATTGTTGATGTTTGTCGGGACGTTGTTCTGGGTACTGGCACAACAGGGCGGCAGTACCATCAGCTTGTTTATCGATC
GCTTTGTGAATCGTCAGGCATTCAATATTGAAGTACCTACAGCACTATTCCAGTCGGTGAATGCAATTGCAGTGATGCTC
GCTGGGGTTGTGCTGGCCTGGCTGGCATCGCCAGAAAGCCGCGGCAACTCAACATTGCGCGTCTGGCTGAAGTTTGCCTT
TGGCTTACTGCTGATGGCTTGTGGCTTTATGTTGTTGGCATTTGATGCCCGACATGCAGCGGCTGACGGTCAAGCGTCAA
TGGGCGTGATGATATCCGGGTTGGCGCTAATGGGCTTTGCCGAACTCTTTATTGACCCGGTGGCGATTGCGCAAATCACG
CGTCTGAAAATGTCTGGCGTATTAACCGGTATTTATATGCTGGCAACAGGCGCGGTCGCCAACTGGCTGGCAGGCGTCGT
GGCACAGCAGACGACAGAGTCGCAAATTAGCGGTATGGCAATTGCAGCTTACCAGCGATTCTTTTCTCAGATGGGAGAGT
GGACGTTGGCTTGTGTCGCGATCATCGTCGTATTGGCCTTTGCTACCCGTTTTCTGTTTAGCACGCCGACGAATATGATA
CAGGAGAGCAACGATTAA

Upstream 100 bases:

>100_bases
CGCTATACCGTTAAGGTATTGAAAGAAGAAAGCAAAAAATAATTAGCTCGTACAAGGGAAGTGGCTTGCCACTTCCCTTT
TTTGCTCATAAGGAGAACAT

Downstream 100 bases:

>100_bases
CTGTCGTAAAAACAATTGGTTATGAATAAATTAACTTTCAGTTTATAACACTAGCAAATCTAGATTAATAAGTCATTTAA
ACCATTTTGATGGTTATTTA

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MKTPSQPRAIYYIVAIQIWEYFSFYGMRALLILYLTHQLGFDDNHAISLFSAYASLVYVTPILGGWLADRLLGNRTAVIA
GALLMTLGHVVLGIDTNSTFSLYLALAIIICGYGLFKSNISCLLGELYDENDHRRDGGFSLLYAAGNIGSIAAPIACGLA
AQWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKFALPVWSWLVVMLCLAPVFFTLLLENDWSGYLLA
IVCLIAAQIIARMMIKFPEHRRALWQIVLLMFVGTLFWVLAQQGGSTISLFIDRFVNRQAFNIEVPTALFQSVNAIAVML
AGVVLAWLASPESRGNSTLRVWLKFAFGLLLMACGFMLLAFDARHAAADGQASMGVMISGLALMGFAELFIDPVAIAQIT
RLKMSGVLTGIYMLATGAVANWLAGVVAQQTTESQISGMAIAAYQRFFSQMGEWTLACVAIIVVLAFATRFLFSTPTNMI
QESND

Sequences:

>Translated_485_residues
MKTPSQPRAIYYIVAIQIWEYFSFYGMRALLILYLTHQLGFDDNHAISLFSAYASLVYVTPILGGWLADRLLGNRTAVIA
GALLMTLGHVVLGIDTNSTFSLYLALAIIICGYGLFKSNISCLLGELYDENDHRRDGGFSLLYAAGNIGSIAAPIACGLA
AQWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKFALPVWSWLVVMLCLAPVFFTLLLENDWSGYLLA
IVCLIAAQIIARMMIKFPEHRRALWQIVLLMFVGTLFWVLAQQGGSTISLFIDRFVNRQAFNIEVPTALFQSVNAIAVML
AGVVLAWLASPESRGNSTLRVWLKFAFGLLLMACGFMLLAFDARHAAADGQASMGVMISGLALMGFAELFIDPVAIAQIT
RLKMSGVLTGIYMLATGAVANWLAGVVAQQTTESQISGMAIAAYQRFFSQMGEWTLACVAIIVVLAFATRFLFSTPTNMI
QESND
>Mature_485_residues
MKTPSQPRAIYYIVAIQIWEYFSFYGMRALLILYLTHQLGFDDNHAISLFSAYASLVYVTPILGGWLADRLLGNRTAVIA
GALLMTLGHVVLGIDTNSTFSLYLALAIIICGYGLFKSNISCLLGELYDENDHRRDGGFSLLYAAGNIGSIAAPIACGLA
AQWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKFALPVWSWLVVMLCLAPVFFTLLLENDWSGYLLA
IVCLIAAQIIARMMIKFPEHRRALWQIVLLMFVGTLFWVLAQQGGSTISLFIDRFVNRQAFNIEVPTALFQSVNAIAVML
AGVVLAWLASPESRGNSTLRVWLKFAFGLLLMACGFMLLAFDARHAAADGQASMGVMISGLALMGFAELFIDPVAIAQIT
RLKMSGVLTGIYMLATGAVANWLAGVVAQQTTESQISGMAIAAYQRFFSQMGEWTLACVAIIVVLAFATRFLFSTPTNMI
QESND

Specific function: Probable proton-dependent permease that transports di- and tripeptides. Shows significantly higher specificity towards dipeptides

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family

Homologues:

Organism=Homo sapiens, GI4827008, Length=232, Percent_Identity=27.1551724137931, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI226371746, Length=199, Percent_Identity=32.1608040201005, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI226371748, Length=191, Percent_Identity=29.8429319371728, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790572, Length=485, Percent_Identity=100, Blast_Score=978, Evalue=0.0,
Organism=Escherichia coli, GI1786927, Length=474, Percent_Identity=57.5949367088608, Blast_Score=533, Evalue=1e-153,
Organism=Escherichia coli, GI1787922, Length=469, Percent_Identity=28.997867803838, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1789911, Length=486, Percent_Identity=27.1604938271605, Blast_Score=167, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17569141, Length=385, Percent_Identity=23.1168831168831, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71987453, Length=186, Percent_Identity=28.494623655914, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24639585, Length=203, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24639583, Length=204, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24639581, Length=204, Percent_Identity=29.4117647058824, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28571098, Length=154, Percent_Identity=31.1688311688312, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28571102, Length=154, Percent_Identity=31.1688311688312, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571100, Length=154, Percent_Identity=31.1688311688312, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YJDL_ECOLI (P39276)

Other databases:

- EMBL:   U14003
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   S56359
- RefSeq:   AP_004632.1
- RefSeq:   NP_418554.1
- ProteinModelPortal:   P39276
- STRING:   P39276
- EnsemblBacteria:   EBESCT00000001463
- EnsemblBacteria:   EBESCT00000016117
- GeneID:   948644
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW4091
- KEGG:   eco:b4130
- EchoBASE:   EB2362
- EcoGene:   EG12469
- eggNOG:   COG3104
- GeneTree:   EBGT00050000010038
- HOGENOM:   HBG586603
- OMA:   FAARFLF
- ProtClustDB:   CLSK2393228
- BioCyc:   EcoCyc:YJDL-MONOMER
- Genevestigator:   P39276
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456
- PANTHER:   PTHR11654:SF6
- TIGRFAMs:   TIGR00924

Pfam domain/function: PF00854 PTR2; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 53055; Mature: 53055

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS50850 MFS; PS01022 PTR2_1; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x188e8c88)-; HASH(0x1947ac28)-; HASH(0x19537b04)-; HASH(0x18d67474)-; HASH(0x195644a4)-; HASH(0x191d7880)-; HASH(0x193038e0)-; HASH(0x18f790ac)-; HASH(0x40522b3c)-; HASH(0x404ed1e4)-; HASH(0x154fddb0)-; HASH(0x195419ac)-; HASH(0x19255330)-; HASH(0x190d4e78)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPSQPRAIYYIVAIQIWEYFSFYGMRALLILYLTHQLGFDDNHAISLFSAYASLVYVT
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
PILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSLYLALAIIICGYGLFKSNI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
SCLLGELYDENDHRRDGGFSLLYAAGNIGSIAAPIACGLAAQWYGWHVGFALAGGGMFIG
HHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LLIFLSGHRHFQSTRSMDKKALTSVKFALPVWSWLVVMLCLAPVFFTLLLENDWSGYLLA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IVCLIAAQIIARMMIKFPEHRRALWQIVLLMFVGTLFWVLAQQGGSTISLFIDRFVNRQA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCE
FNIEVPTALFQSVNAIAVMLAGVVLAWLASPESRGNSTLRVWLKFAFGLLLMACGFMLLA
EEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FDARHAAADGQASMGVMISGLALMGFAELFIDPVAIAQITRLKMSGVLTGIYMLATGAVA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NWLAGVVAQQTTESQISGMAIAAYQRFFSQMGEWTLACVAIIVVLAFATRFLFSTPTNMI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
QESND
CCCCH
>Mature Secondary Structure
MKTPSQPRAIYYIVAIQIWEYFSFYGMRALLILYLTHQLGFDDNHAISLFSAYASLVYVT
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
PILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSLYLALAIIICGYGLFKSNI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
SCLLGELYDENDHRRDGGFSLLYAAGNIGSIAAPIACGLAAQWYGWHVGFALAGGGMFIG
HHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LLIFLSGHRHFQSTRSMDKKALTSVKFALPVWSWLVVMLCLAPVFFTLLLENDWSGYLLA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IVCLIAAQIIARMMIKFPEHRRALWQIVLLMFVGTLFWVLAQQGGSTISLFIDRFVNRQA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCE
FNIEVPTALFQSVNAIAVMLAGVVLAWLASPESRGNSTLRVWLKFAFGLLLMACGFMLLA
EEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FDARHAAADGQASMGVMISGLALMGFAELFIDPVAIAQITRLKMSGVLTGIYMLATGAVA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NWLAGVVAQQTTESQISGMAIAAYQRFFSQMGEWTLACVAIIVVLAFATRFLFSTPTNMI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
QESND
CCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503