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The map label for this gene is wecD [H]

Identifier: 157163264

GI number: 157163264

Start: 4003009

End: 4003554

Strand: Direct

Name: wecD [H]

Synonym: EcHS_A4007

Alternate gene names: 157163264

Gene position: 4003009-4003554 (Clockwise)

Preceding gene: 157163263

Following gene: 157163265

Centisome position: 86.21

GC content: 54.58

Gene sequence:

>546_bases
GTGCAGGCCAAAATTGCGGCATCAAATACGGGTGAACTGGATGCCCTGCAACAGCTGGGATTCTCCCTGGTAGAAGGTGA
AGTTGATTTGGCGCTACCCGTGAACAATGCCAGTGATAGCGGTGCTGTAGTGGCACAAGAGACCGATATTCCCGCATTAC
GTCAGTTAGCCAGCGCCGCATTTGCGCAAAGCCGTTTTCGTGCGCCGTGGTATGCGCCTGACGCCAGCAGTCGCTTTTAT
GCACAGTGGATTGAAAATGCCGTGCGCGGCACCTTTGATCATCAATGTCTGATTTTACGTGCGGCGTCCGGCGATATTCG
CGGCTATGTCTCTTTACGGGAACTCAATGCGACAGATGCGCGAATTGGCCTGCTGGCTGGACGCGGTGCAGGTGCTGAGC
TGATGCAAACGGCGCTAAACTGGGCGTATGCTCGCGGTAAAACAACTTTGCGGGTGGCGACCCAGATGGGCAACACCGCC
GCGCTTAAACGATACATACAAAGTGGTGCGAATGTAGAAAGCACCGCGTACTGGTTATACAGGTGA

Upstream 100 bases:

>100_bases
AACCTGGGAAAACGCCTTCTTTGGTGTTAACAGCGCCATCGTGCGCATTACGTCTGAAGCACCGCTCCTGACGCCAGACG
CGTTAGCGCCGTGGTCACGG

Downstream 100 bases:

>100_bases
TCACATGATTCCATTTAACGCACCGCCGGTGGTGGGAACCGAACTCGACTATATGCAGTCGGCAATGGGTAGCGGCAAAC
TGTGTGGCGATGGCGGTTTT

Product: TDP-fucosamine acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MQAKIAASNTGELDALQQLGFSLVEGEVDLALPVNNASDSGAVVAQETDIPALRQLASAAFAQSRFRAPWYAPDASSRFY
AQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNATDARIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTA
ALKRYIQSGANVESTAYWLYR

Sequences:

>Translated_181_residues
MQAKIAASNTGELDALQQLGFSLVEGEVDLALPVNNASDSGAVVAQETDIPALRQLASAAFAQSRFRAPWYAPDASSRFY
AQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNATDARIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTA
ALKRYIQSGANVESTAYWLYR
>Mature_181_residues
MQAKIAASNTGELDALQQLGFSLVEGEVDLALPVNNASDSGAVVAQETDIPALRQLASAAFAQSRFRAPWYAPDASSRFY
AQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNATDARIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTA
ALKRYIQSGANVESTAYWLYR

Specific function: Transaminase converting thymidine diphosphate(TDP)-4- keto-6-deoxy-D-glucose to TDP-4-amino-4,6-dideoxy-D-galactose, the immediate precursor of the ECA sugar TDP-Fuc4NAc [H]

COG id: COG0454

COG function: function code KR; Histone acetyltransferase HPA2 and related acetyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI145693203, Length=181, Percent_Identity=99.4475138121547, Blast_Score=363, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR012752
- InterPro:   IPR016181
- InterPro:   IPR002110
- InterPro:   IPR020683 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: NA

Molecular weight: Translated: 19545; Mature: 19545

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS50088 ANK_REPEAT ; PS50297 ANK_REP_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAKIAASNTGELDALQQLGFSLVEGEVDLALPVNNASDSGAVVAQETDIPALRQLASAA
CCCEECCCCCCCHHHHHHCCHHEECCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHH
FAQSRFRAPWYAPDASSRFYAQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNATDA
HHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEEECCCCCC
RIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVESTAYWLY
EEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEE
R
C
>Mature Secondary Structure
MQAKIAASNTGELDALQQLGFSLVEGEVDLALPVNNASDSGAVVAQETDIPALRQLASAA
CCCEECCCCCCCHHHHHHCCHHEECCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHH
FAQSRFRAPWYAPDASSRFYAQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNATDA
HHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEEECCCCCC
RIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVESTAYWLY
EEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEE
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503; 8366065 [H]