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The map label for this gene is wzzE

Identifier: 157163259

GI number: 157163259

Start: 3997444

End: 3998490

Strand: Direct

Name: wzzE

Synonym: EcHS_A4002

Alternate gene names: 157163259

Gene position: 3997444-3998490 (Clockwise)

Preceding gene: 157163258

Following gene: 157163260

Centisome position: 86.09

GC content: 52.72

Gene sequence:

>1047_bases
ATGACACAACCAATGCCTGGGAAACCGGCCGAAGACGCTGAAAATGAACTGGATATTCGTGGGTTGTTTCGTACCTTGTG
GGCTGGGAAGCTATGGATTATTGGCATGGGGCTGGCGTTTGCGTTAATCGCGCTGGCGTATACGTTTTTTGCTCGTCAGG
AGTGGAGCTCGACGGCGATTACCGATCGTCCAACGGTGAATATGCTGGGGGGATATTACTCGCAGCAGCAATTTTTGCGT
AACCTGGATGTCCGTTCAAACATGGCTTCTGCCGACCAACCATCGGTCATGGACGAAGCCTATAAAGAGTTTGTTATGCA
ACTGGCCTCGTGGGATACCCGCAGAGAGTTCTGGCTGCAAACCGACTATTACAAACAGCGGATGGTGGGCAACAGCAAAG
CCGATGCGGCGTTGCTGGATGAAATGATTAACAACATCCAGTTTATCCCCGGAGACTTTACCCGCGCGGTCAATGACAGC
GTGAAGCTTATTGCCGAAACCGCGCCTGACGCTAATAACCTGTTACGTCAGTATGTTGCTTTTGCCAGCCAGCGTGCAGC
CAGCCATCTGAATGATGAGCTGAAAGGCGCATGGGCGGCGCGTACCATCCAGATGAAAGCTCAGGTGAAGCGTCAGGAAG
AGGTGGCGAAAGCCATCTACGACCGCCGGATGAACAGCATTGAGCAGGCGCTGAAAATTGCTGAGCAGCATAATATTTCG
CGCAGTGCGACAGATGTACCTGCCGAGGAATTACCTGATTCAGAAATGTTCCTGCTTGGGCGTCCAATGCTTCAGGCTCG
ACTGGAAAATTTACAGGCCGTCGGTCCGGCCTTTGATCTCGACTATGATCAGAATCGGGCCATGTTAAACACCCTGAATG
TTGGTCCAACCCTGGATCCGCGTTTTCAGACCTATCGCTATTTGCGTACGCCGGAAGAACCGGTAAAACGCGATAGCCCA
CGTCGTGCCTTCCTGATGATTATGTGGGGCATTGTCGGGGGGCTGATCGGGGCTGGTGTCGCATTAACCCGCCGTTGCTC
GAAATAG

Upstream 100 bases:

>100_bases
AGCGTGCCTGGAAAGTTGCTCGCTTTATTAAGCGCGTAAAACGCAGACTGCGTAGAAATCGTGGTGGCAGCCCCAATTTA
ACCAAATAAATGAGGATGTG

Downstream 100 bases:

>100_bases
CAACACTGCTGCGGTGAGCGCAAAGGCGCTCGCCGCTTATTCGAAGAGAATCGATGTGAAAGTACTGACTGTATTTGGTA
CGCGCCCGGAAGCCATCAAG

Product: lipopolysaccharide biosynthesis protein WzzE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MTQPMPGKPAEDAENELDIRGLFRTLWAGKLWIIGMGLAFALIALAYTFFARQEWSSTAITDRPTVNMLGGYYSQQQFLR
NLDVRSNMASADQPSVMDEAYKEFVMQLASWDTRREFWLQTDYYKQRMVGNSKADAALLDEMINNIQFIPGDFTRAVNDS
VKLIAETAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTIQMKAQVKRQEEVAKAIYDRRMNSIEQALKIAEQHNIS
RSATDVPAEELPDSEMFLLGRPMLQARLENLQAVGPAFDLDYDQNRAMLNTLNVGPTLDPRFQTYRYLRTPEEPVKRDSP
RRAFLMIMWGIVGGLIGAGVALTRRCSK

Sequences:

>Translated_348_residues
MTQPMPGKPAEDAENELDIRGLFRTLWAGKLWIIGMGLAFALIALAYTFFARQEWSSTAITDRPTVNMLGGYYSQQQFLR
NLDVRSNMASADQPSVMDEAYKEFVMQLASWDTRREFWLQTDYYKQRMVGNSKADAALLDEMINNIQFIPGDFTRAVNDS
VKLIAETAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTIQMKAQVKRQEEVAKAIYDRRMNSIEQALKIAEQHNIS
RSATDVPAEELPDSEMFLLGRPMLQARLENLQAVGPAFDLDYDQNRAMLNTLNVGPTLDPRFQTYRYLRTPEEPVKRDSP
RRAFLMIMWGIVGGLIGAGVALTRRCSK
>Mature_347_residues
TQPMPGKPAEDAENELDIRGLFRTLWAGKLWIIGMGLAFALIALAYTFFARQEWSSTAITDRPTVNMLGGYYSQQQFLRN
LDVRSNMASADQPSVMDEAYKEFVMQLASWDTRREFWLQTDYYKQRMVGNSKADAALLDEMINNIQFIPGDFTRAVNDSV
KLIAETAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTIQMKAQVKRQEEVAKAIYDRRMNSIEQALKIAEQHNISR
SATDVPAEELPDSEMFLLGRPMLQARLENLQAVGPAFDLDYDQNRAMLNTLNVGPTLDPRFQTYRYLRTPEEPVKRDSPR
RAFLMIMWGIVGGLIGAGVALTRRCSK

Specific function: Unknown

COG id: COG3765

COG function: function code M; Chain length determinant protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the wzzB/cld/rol family

Homologues:

Organism=Escherichia coli, GI87082332, Length=348, Percent_Identity=100, Blast_Score=717, Evalue=0.0,
Organism=Escherichia coli, GI87082029, Length=338, Percent_Identity=24.8520710059172, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786802, Length=363, Percent_Identity=22.038567493113, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WZZE_ECO57 (P0AG01)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   F91218
- PIR:   H86064
- RefSeq:   NP_290416.1
- RefSeq:   NP_312745.1
- PDB:   3B8O
- PDBsum:   3B8O
- ProteinModelPortal:   P0AG01
- SMR:   P0AG01
- DIP:   DIP-46395N
- EnsemblBacteria:   EBESCT00000027103
- EnsemblBacteria:   EBESCT00000056439
- GeneID:   915243
- GeneID:   960383
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z5296
- KEGG:   ecs:ECs4718
- GeneTree:   EBGT00050000009085
- HOGENOM:   HBG416084
- OMA:   YDTRREF
- ProtClustDB:   PRK11638
- BioCyc:   ECOL83334:ECS4718-MONOMER
- InterPro:   IPR003856

Pfam domain/function: PF02706 Wzz

EC number: NA

Molecular weight: Translated: 39490; Mature: 39358

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15112c54)-; HASH(0x187aac30)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPMPGKPAEDAENELDIRGLFRTLWAGKLWIIGMGLAFALIALAYTFFARQEWSSTAI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TDRPTVNMLGGYYSQQQFLRNLDVRSNMASADQPSVMDEAYKEFVMQLASWDTRREFWLQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
TDYYKQRMVGNSKADAALLDEMINNIQFIPGDFTRAVNDSVKLIAETAPDANNLLRQYVA
HHHHHHHHCCCCCHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FASQRAASHLNDELKGAWAARTIQMKAQVKRQEEVAKAIYDRRMNSIEQALKIAEQHNIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RSATDVPAEELPDSEMFLLGRPMLQARLENLQAVGPAFDLDYDQNRAMLNTLNVGPTLDP
CCCCCCCHHHCCCCCEEHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCC
RFQTYRYLRTPEEPVKRDSPRRAFLMIMWGIVGGLIGAGVALTRRCSK
HHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
TQPMPGKPAEDAENELDIRGLFRTLWAGKLWIIGMGLAFALIALAYTFFARQEWSSTAI
CCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TDRPTVNMLGGYYSQQQFLRNLDVRSNMASADQPSVMDEAYKEFVMQLASWDTRREFWLQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
TDYYKQRMVGNSKADAALLDEMINNIQFIPGDFTRAVNDSVKLIAETAPDANNLLRQYVA
HHHHHHHHCCCCCHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FASQRAASHLNDELKGAWAARTIQMKAQVKRQEEVAKAIYDRRMNSIEQALKIAEQHNIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RSATDVPAEELPDSEMFLLGRPMLQARLENLQAVGPAFDLDYDQNRAMLNTLNVGPTLDP
CCCCCCCHHHCCCCCEEHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCC
RFQTYRYLRTPEEPVKRDSPRRAFLMIMWGIVGGLIGAGVALTRRCSK
HHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796