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The map label for this gene is bglA [H]

Identifier: 157162361

GI number: 157162361

Start: 3071175

End: 3072614

Strand: Direct

Name: bglA [H]

Synonym: EcHS_A3060

Alternate gene names: 157162361

Gene position: 3071175-3072614 (Clockwise)

Preceding gene: 157162358

Following gene: 157162370

Centisome position: 66.14

GC content: 51.04

Gene sequence:

>1440_bases
ATGATAGTGAAAAAACTCACCTTACCGAAAGATTTCTTATGGGGCGGCGCAGTTGCCGCTCATCAGGTCGAAGGCGGCTG
GAACAAAGGCGGCAAAGGGCCGAGCATTTGTGACGTTCTGACCGGTGGCGCACACGGCGTGCCGCGCGAAATCACCAAAG
AAGTCTTGCCAGGCAAATACTATCCAAACCATGAAGCCGTTGATTTTTATGGTCACTACAAGGAAGACATCAAGCTATTT
GCCGAAATGGGCTTCAAATGTTTTCGGACTTCCATCGCCTGGACGCGTATTTTTCCAAAAGGTGATGAAGCTCAGCCAAA
CGAAGAAGGGCTGAAGTTCTACGATGATATGTTCGATGAACTGCTGAAATACAACATCGAACCGGTGATAACCCTCTCCC
ACTTTGAAATGCCGCTGCATCTGGTGCAGCAATACGGTAGCTGGACCAACCGTAAAGTCGTTGATTTCTTTGTCCGTTTC
GCGGAAGTGGTATTCGAACGCTACAAGCATAAAGTCAAATACTGGATGACCTTCAACGAAATAAACAACCAGCGTAACTG
GCGTGCGCCGCTGTTTGGTTACTGCTGCTCCGGCGTGGTGTATACCGAGCATGACAACCCGGAAGAGACGATGTACCAGG
TGCTGCATCACCAGTTTGTCGCCAGCGCCCTGGCAGTGAAAGCCGCGCGTCGCATTAACCCGGAGATGAAAGTCGGCTGT
ATGCTGGCGATGGTGCCGCTCTATCCCTACTCCTGTAACCCGGACGATGTGATGTTCGCTCAGGAGTCGATGCGCGAACG
CTACGTCTTTACCGATGTGCAGCTACGCGGCTATTACCCGTCCTATGTGTTGAACGAGTGGGAGCGTCGCGGATTTAACA
TCAAAATGGAAGATGGCGATCTGGATGTACTGCGTGAAGGCACCTGCGATTATCTTGGTTTCAGCTATTACATGACCAAC
GCAGTGAAGGCCGAAGGCGGCACCGGCGATGCGATCTCTGGTTTTGAAGGCAGCGTACCGAACCCGTATGTTAAAGCGTC
TGACTGGGGCTGGCAGATTGATCCAGTAGGTCTGCGCTATGCCCTTTGCGAACTGTATGAGCGTTATCAGAGGCCGCTGT
TTATTGTCGAAAACGGTTTTGGCGCTTACGACAAAGTGGAAGAAGATGGCAGCATCAACGACGACTACCGCATTGACTAC
CTGCGCGCCCATATTGAAGAGATGAAAAAAGCAGTGACTTACGATGGTGTGGATCTGATGGGCTACACACCGTGGGGCTG
CATCGACTGCGTGTCATTCACTACCGGGCAGTACAGCAAACGCTACGGCTTTATCTATGTGAATAAACATGACGACGGTA
CTGGCGATATGTCGCGTTCACGTAAGAAGAGCTTTAACTGGTACAAAGAGGTGATTGCCAGCAACGGCGAGAAGCTTTAA

Upstream 100 bases:

>100_bases
TTACGCCCAGCCAGAATGTCATCCTGGAAACGTTGAAAAAAAGTGATGTCGTTTGGCTGCATGGTACTATTTCCTGTAAG
AATTGACTCATCTGGAGCCT

Downstream 100 bases:

>100_bases
GTCGATGAAGTACCGGATGCAATACTTGTTGCATCCGGTCAGACAACTTCCCTGTTTTATTTCCCGCCCGCCAAATCGAT
AAAACTTCCCGTGACGTAAG

Product: 6-phospho-beta-glucosidase BglA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MIVKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHGVPREITKEVLPGKYYPNHEAVDFYGHYKEDIKLF
AEMGFKCFRTSIAWTRIFPKGDEAQPNEEGLKFYDDMFDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRF
AEVVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHDNPEETMYQVLHHQFVASALAVKAARRINPEMKVGC
MLAMVPLYPYSCNPDDVMFAQESMRERYVFTDVQLRGYYPSYVLNEWERRGFNIKMEDGDLDVLREGTCDYLGFSYYMTN
AVKAEGGTGDAISGFEGSVPNPYVKASDWGWQIDPVGLRYALCELYERYQRPLFIVENGFGAYDKVEEDGSINDDYRIDY
LRAHIEEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDDGTGDMSRSRKKSFNWYKEVIASNGEKL

Sequences:

>Translated_479_residues
MIVKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHGVPREITKEVLPGKYYPNHEAVDFYGHYKEDIKLF
AEMGFKCFRTSIAWTRIFPKGDEAQPNEEGLKFYDDMFDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRF
AEVVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHDNPEETMYQVLHHQFVASALAVKAARRINPEMKVGC
MLAMVPLYPYSCNPDDVMFAQESMRERYVFTDVQLRGYYPSYVLNEWERRGFNIKMEDGDLDVLREGTCDYLGFSYYMTN
AVKAEGGTGDAISGFEGSVPNPYVKASDWGWQIDPVGLRYALCELYERYQRPLFIVENGFGAYDKVEEDGSINDDYRIDY
LRAHIEEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDDGTGDMSRSRKKSFNWYKEVIASNGEKL
>Mature_479_residues
MIVKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHGVPREITKEVLPGKYYPNHEAVDFYGHYKEDIKLF
AEMGFKCFRTSIAWTRIFPKGDEAQPNEEGLKFYDDMFDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRF
AEVVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHDNPEETMYQVLHHQFVASALAVKAARRINPEMKVGC
MLAMVPLYPYSCNPDDVMFAQESMRERYVFTDVQLRGYYPSYVLNEWERRGFNIKMEDGDLDVLREGTCDYLGFSYYMTN
AVKAEGGTGDAISGFEGSVPNPYVKASDWGWQIDPVGLRYALCELYERYQRPLFIVENGFGAYDKVEEDGSINDDYRIDY
LRAHIEEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDDGTGDMSRSRKKSFNWYKEVIASNGEKL

Specific function: Unknown

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=503, Percent_Identity=30.2186878727634, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI32481206, Length=491, Percent_Identity=29.5315682281059, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI13273313, Length=491, Percent_Identity=26.4765784114053, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI24497614, Length=486, Percent_Identity=28.3950617283951, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI28376633, Length=484, Percent_Identity=26.8595041322314, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI190360571, Length=109, Percent_Identity=32.1100917431193, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367174, Length=479, Percent_Identity=99.7912317327766, Blast_Score=1001, Evalue=0.0,
Organism=Escherichia coli, GI1789070, Length=478, Percent_Identity=51.0460251046025, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI2367270, Length=474, Percent_Identity=50.8438818565401, Blast_Score=471, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI17552856, Length=483, Percent_Identity=28.9855072463768, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17539390, Length=488, Percent_Identity=27.2540983606557, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI21356577, Length=508, Percent_Identity=27.1653543307087, Blast_Score=162, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 55347; Mature: 55347

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHGVPREITKEVLPGKY
CCEECCCCCHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCC
YPNHEAVDFYGHYKEDIKLFAEMGFKCFRTSIAWTRIFPKGDEAQPNEEGLKFYDDMFDE
CCCCCCEEHHCCHHHHHHHHHHHCHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHH
LLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRFAEVVFERYKHKVKYWMTFNE
HHHCCCCEEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEHH
INNQRNWRAPLFGYCCSGVVYTEHDNPEETMYQVLHHQFVASALAVKAARRINPEMKVGC
HCCCCCCCCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
MLAMVPLYPYSCNPDDVMFAQESMRERYVFTDVQLRGYYPSYVLNEWERRGFNIKMEDGD
HHHHHHCCCCCCCCCHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHCCCEEEECCCC
LDVLREGTCDYLGFSYYMTNAVKAEGGTGDAISGFEGSVPNPYVKASDWGWQIDPVGLRY
HHHHHCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEECCCCEEECCHHHHH
ALCELYERYQRPLFIVENGFGAYDKVEEDGSINDDYRIDYLRAHIEEMKKAVTYDGVDLM
HHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEC
GYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDDGTGDMSRSRKKSFNWYKEVIASNGEKL
CCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIVKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHGVPREITKEVLPGKY
CCEECCCCCHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCC
YPNHEAVDFYGHYKEDIKLFAEMGFKCFRTSIAWTRIFPKGDEAQPNEEGLKFYDDMFDE
CCCCCCEEHHCCHHHHHHHHHHHCHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHH
LLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRFAEVVFERYKHKVKYWMTFNE
HHHCCCCEEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEHH
INNQRNWRAPLFGYCCSGVVYTEHDNPEETMYQVLHHQFVASALAVKAARRINPEMKVGC
HCCCCCCCCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
MLAMVPLYPYSCNPDDVMFAQESMRERYVFTDVQLRGYYPSYVLNEWERRGFNIKMEDGD
HHHHHHCCCCCCCCCHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHCCCEEEECCCC
LDVLREGTCDYLGFSYYMTNAVKAEGGTGDAISGFEGSVPNPYVKASDWGWQIDPVGLRY
HHHHHCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEECCCCEEECCHHHHH
ALCELYERYQRPLFIVENGFGAYDKVEEDGSINDDYRIDYLRAHIEEMKKAVTYDGVDLM
HHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEC
GYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDDGTGDMSRSRKKSFNWYKEVIASNGEKL
CCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]